NO883554D0 - Fremgangsmaate til isolering av basiske proteiner fra proteinblandinger som inneholder slike basiske proteiner. - Google Patents

Fremgangsmaate til isolering av basiske proteiner fra proteinblandinger som inneholder slike basiske proteiner.

Info

Publication number
NO883554D0
NO883554D0 NO883554A NO883554A NO883554D0 NO 883554 D0 NO883554 D0 NO 883554D0 NO 883554 A NO883554 A NO 883554A NO 883554 A NO883554 A NO 883554A NO 883554 D0 NO883554 D0 NO 883554D0
Authority
NO
Norway
Prior art keywords
basic proteins
isolation
procedure
ingredients containing
protein ingredients
Prior art date
Application number
NO883554A
Other languages
English (en)
Other versions
NO883554L (no
NO175004C (no
NO175004B (no
Inventor
Michael Dorschug
Rainer Obermeier
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO883554D0 publication Critical patent/NO883554D0/no
Publication of NO883554L publication Critical patent/NO883554L/no
Publication of NO175004B publication Critical patent/NO175004B/no
Publication of NO175004C publication Critical patent/NO175004C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO883554A 1987-08-11 1988-08-10 Fremgangsmåte til isolering av basiske insuliner fra proteinblandinger som inneholder slike basiske insuliner NO175004C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873726655 DE3726655A1 (de) 1987-08-11 1987-08-11 Verfahren zur isolierung basischer proteine aus proteingemischen, welche solche basischen proteine enthalten

Publications (4)

Publication Number Publication Date
NO883554D0 true NO883554D0 (no) 1988-08-10
NO883554L NO883554L (no) 1989-02-13
NO175004B NO175004B (no) 1994-05-09
NO175004C NO175004C (no) 1994-08-17

Family

ID=6333496

Family Applications (1)

Application Number Title Priority Date Filing Date
NO883554A NO175004C (no) 1987-08-11 1988-08-10 Fremgangsmåte til isolering av basiske insuliner fra proteinblandinger som inneholder slike basiske insuliner

Country Status (19)

Country Link
US (1) US5101013A (no)
EP (1) EP0305760B1 (no)
JP (1) JP2587867B2 (no)
KR (1) KR0129539B1 (no)
AT (1) ATE96447T1 (no)
AU (1) AU609170B2 (no)
CA (1) CA1340237C (no)
DE (2) DE3726655A1 (no)
DK (1) DK173502B1 (no)
ES (1) ES2047007T3 (no)
FI (1) FI91875C (no)
HU (1) HU198218B (no)
IE (1) IE61557B1 (no)
IL (1) IL87385A (no)
NO (1) NO175004C (no)
NZ (1) NZ225746A (no)
PH (1) PH26874A (no)
PT (1) PT88230B (no)
ZA (1) ZA885871B (no)

Families Citing this family (31)

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Publication number Priority date Publication date Assignee Title
EP0600372B1 (de) * 1992-12-02 1997-02-05 Hoechst Aktiengesellschaft Verfahren zur Gewinnung von Proinsulin mit korrekt verbundenen Cystinbrücken
DK0821006T3 (da) 1996-07-26 2004-08-16 Aventis Pharma Gmbh Insulinderivater med öget zinkbinding
DE19652713C2 (de) * 1996-12-18 2001-11-22 Aventis Pharma Gmbh Verfahren zur Reinigung von Insulin und Insulinderivaten durch Chromatographie an stark saurem Kationenaustauscher
KR100341297B1 (ko) * 1997-03-29 2002-11-16 주식회사종근당 재조합활성형프로인슐린의분리.정제방법
DE19726167B4 (de) 1997-06-20 2008-01-24 Sanofi-Aventis Deutschland Gmbh Insulin, Verfahren zu seiner Herstellung und es enthaltende pharmazeutische Zubereitung
DE19825447A1 (de) 1998-06-06 1999-12-09 Hoechst Marion Roussel De Gmbh Neue Insulinanaloga mit erhöhter Zinkbildung
US6444788B1 (en) * 1999-03-15 2002-09-03 Novo Nordisk A/S Ion exchange chromatography of GLP-1, analogs and derivatives thereof
US6451987B1 (en) * 1999-03-15 2002-09-17 Novo Nordisk A/S Ion exchange chromatography of proteins and peptides
ATE509028T1 (de) * 1999-03-15 2011-05-15 Novo Nordisk As Ionen-austausch-chromatographische trennung von glp-1 und verwandten peptiden
DE10114178A1 (de) 2001-03-23 2002-10-10 Aventis Pharma Gmbh Zinkfreie und zinkarme Insulinzubereitungen mit verbesserter Stabilität
DE10227232A1 (de) * 2002-06-18 2004-01-15 Aventis Pharma Deutschland Gmbh Saure Insulinzubereitungen mit verbesserter Stabilität
DE10235168A1 (de) * 2002-08-01 2004-02-12 Aventis Pharma Deutschland Gmbh Verfahren zur Reinigung von Preproinsulin
US7193035B2 (en) * 2002-10-29 2007-03-20 Sanofi-Aventis Deutschland Gmbh Crystals of insulin analogs and processes for their preparation
SE0300791D0 (sv) * 2003-03-20 2003-03-20 Amersham Biosciences Ab Use of ph-responsive polymers
EP1664108B1 (en) * 2003-08-21 2009-10-14 Novo Nordisk A/S Separation of polypeptides comprising a racemized amino acid
EP1958879B1 (en) * 2005-08-04 2012-07-11 Toyo Seikan Kaisha, Ltd. Method for sterilization of plastic bottle
KR101820024B1 (ko) 2008-10-17 2018-01-18 사노피-아벤티스 도이칠란트 게엠베하 인슐린과 ｇｌｐ－1 효능제의 병용물
FR2947818B1 (fr) * 2009-07-09 2011-07-29 Inst Superieur Des Sciences Agronomiques Agroalimentaires Horticoles Et Du Paysage Agro Campus Ouest Utilisation d'un coproduit issu d'un procede d'extraction du lysozyme a partir de blanc d'oeuf, pour l'obtention d'au moins une proteine basique de blanc d'oeuf
HUE037735T2 (hu) 2009-11-13 2018-09-28 Sanofi Aventis Deutschland DesPro36exendin-4(1-39)-Lys6-NH2-t és metionint tartalmazó gyógyszerkészítmény
ES2534191T3 (es) 2009-11-13 2015-04-20 Sanofi-Aventis Deutschland Gmbh Composición farmacéutica que comprende un agonista de GLP-1, una insulina y metionina
BR112013004756B1 (pt) 2010-08-30 2020-04-28 Sanofi Aventis Deutschland uso de ave0010 para a fabricação de um medicamento para o tratamento da diabetes melito tipo 2
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
RU2650616C2 (ru) 2011-08-29 2018-04-16 Санофи-Авентис Дойчланд Гмбх Фармацевтическая комбинация для применения при гликемическом контроле у пациентов с сахарным диабетом 2 типа
TWI559929B (en) 2011-09-01 2016-12-01 Sanofi Aventis Deutschland Pharmaceutical composition for use in the treatment of a neurodegenerative disease
JP6093364B2 (ja) * 2011-09-30 2017-03-08 ジーイー・ヘルスケア・バイオプロセス・アールアンドディ・アクチボラグ 生体分子の精製方法
US10421795B2 (en) * 2012-12-17 2019-09-24 Merck Sharp & Dohme Corp. Process for purifying insulin and analogues thereof
WO2015138548A1 (en) 2014-03-14 2015-09-17 Merck Sharp & Dohme Corp. Purifying insulin using cation exchange and reverse phase chromatography in the presence of an organic modifier and elevated temperature
JP6970615B2 (ja) 2014-12-12 2021-11-24 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング インスリングラルギン／リキシセナチド固定比処方
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患之治療
EP3783009A1 (en) * 2017-02-10 2021-02-24 Mitsubishi Chemical Corporation Separating agent for human insulin purification and human insulin purification method

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2629568C3 (de) * 1976-07-01 1981-09-10 Hoechst Ag, 6000 Frankfurt Verfahren zur Reinigung von Insulin, seinen Analogen und Derivaten
NL7713966A (nl) * 1976-12-27 1978-06-29 Univ Minnesota Werkwijze voor het behandelen van insuline.
DK311477A (da) * 1977-07-08 1979-01-09 Leo Lab Fremgangsmaade ved fremstilling af rent insulin
US4459226A (en) * 1982-02-26 1984-07-10 Eli Lilly And Company Process for recovering insulin
DD247684A1 (de) * 1983-04-14 1987-07-15 Ulrich Krabiell Verfahren zur isolierung von insulinderivaten
DE3486216T2 (de) * 1983-04-25 1994-02-17 Chiron Corp Hybrid-DNS-Synthesis von reifen insulinähnlichen Wachstumsfaktoren.
DE3440988A1 (de) * 1984-11-09 1986-07-10 Hoechst Ag, 6230 Frankfurt Verfahren zur spaltung von peptiden und proteinen an der methionyl-bindung
DE3511269A1 (de) * 1985-04-12 1986-10-09 Veb Berlin-Chemie, Ddr 1199 Berlin Verfahren zur reinigung von insulin
JPS6379591A (ja) * 1986-09-22 1988-04-09 Mitsui Toatsu Chem Inc ｔＰＡの精製方法
AU607988B2 (en) * 1987-04-21 1991-03-21 Southern Cross Biotech Pty Ltd. Production of proteins in active forms
ES2064412T3 (es) * 1988-10-26 1995-02-01 American Cyanamid Co Procedimiento para reducir el contenido de aglomerado de materiales tipo hormona del crecimiento.

Also Published As

Publication number Publication date
CA1340237C (en) 1998-12-15
FI883708A0 (fi) 1988-08-09
FI91875B (fi) 1994-05-13
IL87385A0 (en) 1989-01-31
AU609170B2 (en) 1991-04-26
NO883554L (no) 1989-02-13
PT88230B (pt) 1995-03-01
DK447688A (da) 1989-02-12
JP2587867B2 (ja) 1997-03-05
DE3885214D1 (de) 1993-12-02
FI91875C (fi) 1994-08-25
EP0305760A3 (en) 1990-06-06
HU198218B (en) 1989-08-28
KR0129539B1 (ko) 1998-04-04
DK173502B1 (da) 2001-01-08
NZ225746A (en) 1990-11-27
DK447688D0 (da) 1988-08-10
EP0305760A2 (de) 1989-03-08
FI883708A (fi) 1989-02-12
HUT47958A (en) 1989-04-28
NO175004C (no) 1994-08-17
US5101013A (en) 1992-03-31
NO175004B (no) 1994-05-09
IE61557B1 (en) 1994-11-16
IL87385A (en) 1993-08-18
KR890003799A (ko) 1989-04-18
ATE96447T1 (de) 1993-11-15
ES2047007T3 (es) 1994-02-16
AU2059188A (en) 1989-02-16
PT88230A (pt) 1989-06-30
JPS6486896A (en) 1989-03-31
IE882441L (en) 1989-02-11
ZA885871B (en) 1989-04-26
DE3726655A1 (de) 1989-02-23
EP0305760B1 (de) 1993-10-27
PH26874A (en) 1992-11-16

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