DK346783A - Triphenylimidazolyloxyalkansyrer og derivater deraf, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater indeholdende disse forbindelser - Google Patents

Triphenylimidazolyloxyalkansyrer og derivater deraf, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater indeholdende disse forbindelser Download PDF

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Publication number
DK346783A
DK346783A DK346783A DK346783A DK346783A DK 346783 A DK346783 A DK 346783A DK 346783 A DK346783 A DK 346783A DK 346783 A DK346783 A DK 346783A DK 346783 A DK346783 A DK 346783A
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DK
Denmark
Prior art keywords
acids
triphenylimidazolyloxyalkanic
procedures
derivatives
preparing
Prior art date
Application number
DK346783A
Other languages
English (en)
Other versions
DK346783D0 (da
DK158723C (da
DK158723B (da
Inventor
Hans-Heiner Lautenschlaeger
Andre Welter
Gerd Hilboll
Johannes Winkelmann
Gerrit Prop
Axel Brekle
Ottfried Zierenberg
Original Assignee
Nattermann A & Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nattermann A & Cie filed Critical Nattermann A & Cie
Publication of DK346783D0 publication Critical patent/DK346783D0/da
Publication of DK346783A publication Critical patent/DK346783A/da
Publication of DK158723B publication Critical patent/DK158723B/da
Application granted granted Critical
Publication of DK158723C publication Critical patent/DK158723C/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/70One oxygen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
DK346783A 1982-07-29 1983-07-28 Analogifremgangsmaade til fremstilling af triphenylimidazol-2-yloxyalkansyrer og derivater deraf DK158723C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3228271A DE3228271A1 (de) 1982-07-29 1982-07-29 Triphenylimidazolyloxyalkansaeuren und ihre derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3228271 1982-07-29

Publications (4)

Publication Number Publication Date
DK346783D0 DK346783D0 (da) 1983-07-28
DK346783A true DK346783A (da) 1984-01-30
DK158723B DK158723B (da) 1990-07-09
DK158723C DK158723C (da) 1990-12-10

Family

ID=6169571

Family Applications (1)

Application Number Title Priority Date Filing Date
DK346783A DK158723C (da) 1982-07-29 1983-07-28 Analogifremgangsmaade til fremstilling af triphenylimidazol-2-yloxyalkansyrer og derivater deraf

Country Status (13)

Country Link
US (1) US4460598A (da)
EP (1) EP0104342B1 (da)
JP (1) JPS5951269A (da)
AT (1) ATE25246T1 (da)
DE (2) DE3228271A1 (da)
DK (1) DK158723C (da)
ES (1) ES8404332A1 (da)
FI (1) FI79302C (da)
GR (1) GR78654B (da)
IE (1) IE55485B1 (da)
NO (1) NO160579C (da)
PT (1) PT77125B (da)
ZA (1) ZA834648B (da)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3323870A1 (de) * 1983-07-02 1985-01-03 A. Nattermann & Cie GmbH, 5000 Köln Neue imidazol-2-ylthioalkansaeuren und ihre derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
US4598149A (en) * 1984-03-02 1986-07-01 Merck & Co., Inc. 3-amino-2-hydroxypropyl of pyrimidin-4-one useful as antihypertensive, cardioprotective, antiarrythmic, and antianginal agents
DE3504678A1 (de) * 1985-02-12 1986-08-14 A. Nattermann & Cie GmbH, 5000 Köln Neue imidazolyl-oxyalkansaeuren und -thioalkansaeuren, ihre derivate und verfahren zu ihrer herstellung
DE3504680A1 (de) * 1985-02-12 1986-08-14 A. Nattermann & Cie GmbH, 5000 Köln Neue ether des 2-hydroxyimidazols, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3504679A1 (de) * 1985-02-12 1986-08-14 A. Nattermann & Cie GmbH, 5000 Köln Amide der 2-imidazolyloxyalkansaeuren, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3504677A1 (de) * 1985-02-12 1986-08-14 A. Nattermann & Cie GmbH, 5000 Köln Neue imidazol-2-yloxyalkansaeuren und ihre derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
JPH0680057B2 (ja) * 1986-04-28 1994-10-12 保土谷化学工業株式会社 トリフエニルイミダゾ−ル及びその二量体
NO890522L (no) * 1988-02-25 1989-08-28 Bayer Ag Substituerte imidazolinoner og imidazolinthioner.
US4900744A (en) * 1988-09-14 1990-02-13 E. I. Du Pont De Nemours And Company Antihypercholesterolemic 4,5-diaryl-2-substituted thioimidazoles
US5166214A (en) * 1988-12-05 1992-11-24 Du Pont Merck Pharmaceutical Company Use of imidazoles for the treatment of atherosclerosis
CA2014537A1 (en) * 1989-04-26 1990-10-26 Yoshio Hayashi 4-imidazoline derivatives
US4994482A (en) * 1989-07-31 1991-02-19 Bristol-Myers Squibb Company Arylpyrazol derivatives as anti-platelet agents, compositions and use
US5019572A (en) * 1990-02-07 1991-05-28 Merck & Co., Inc. Imidazole compounds and their use as transglutaminase inhibitors
US5262540A (en) * 1989-12-20 1993-11-16 Bristol-Myers Squibb Company [2(4,5-diaryl-2 oxazoyl substituted phenoxy alkanoic acid and esters
US5152988A (en) * 1990-02-07 1992-10-06 Merck & Co., Inc. Imidazole compounds in compositions and methods in thrombolytic therapy
US5011851A (en) * 1990-02-13 1991-04-30 Bristol-Myers Squibb Co. Imidazole carboxylic acids and esters and inhibition of blood platelet aggregation therewith
CA2036192A1 (en) 1990-02-13 1991-08-14 Nicholas Meanwell Heterocyclic carboxylic acids and esters
GB9019838D0 (en) * 1990-09-11 1990-10-24 Smith Kline French Lab Compounds
US5428041A (en) * 1991-05-31 1995-06-27 The Du Pont Merck Pharmaceutical Company Antihypercholesterolemic bis-trifluoromethyl-substituted imidazolines and derivatives thereof
US5179117A (en) * 1991-12-20 1993-01-12 Du Pont Merck Pharmaceutical Company Antihypercholesterolemic 2-substituted imidazoles
PT626969E (pt) * 1992-02-11 2000-11-30 Smithkline Beecham Corp Inibidores de co.a-it e de p.a.f.
US5348969A (en) * 1992-04-03 1994-09-20 Bristol-Myers Squibb Company Diphenyloxazolyl-oxazoles as platelet aggregation inhibitors
US5254576A (en) * 1992-04-03 1993-10-19 Bristol-Myers Squibb Company Diphenyl-heterocyclic-oxazole as platelet aggregation inhibitors
US5187188A (en) * 1992-04-03 1993-02-16 Bristol-Myers Squibb Company Oxazole carboxylic acid derivatives
US5364875A (en) * 1992-05-11 1994-11-15 The Du Pont Merck Pharmaceutical Company Imidazoles linked to bicyclic heterocyclic groups for the treatment of atherosclerosis
US5310748A (en) * 1992-05-11 1994-05-10 The Du Pont Merck Pharmaceutical Company Imidazoles for the treatment of atherosclerosis
US5362879A (en) * 1993-04-15 1994-11-08 Bristol-Myers Squibb Company 4-5-diphenyloxazole derivatives as inhibitors of blood platelet aggregation
SE527381C3 (sv) * 2003-04-14 2006-03-21 Linnman Elektronik Ab Gemensam fältbuss för överföring av data och energi

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3636003A (en) * 1969-11-17 1972-01-18 Geigy Chem Corp Substituted 2-mercaptoimidazole derivatives
DE2934746A1 (de) * 1979-08-28 1981-03-19 A. Nattermann & Cie GmbH, 5000 Köln Oxoimidazolinalkansaeuren, deren salze und ester sowie verfahren zu ihrer herstellung und diese enthaltende arzneimittel
DE2950478A1 (de) * 1979-12-14 1981-06-19 A. Nattermann & Cie GmbH, 5000 Köln 4,5-diaryl-4-imidazolin-2-on-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3042466A1 (de) * 1980-11-11 1982-06-16 A. Nattermann & Cie GmbH, 5000 Köln N-substituierte (omega) -(2-oxo-4-imidazolin-l-yl)-alkansaeure-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate

Also Published As

Publication number Publication date
FI832730A0 (fi) 1983-07-28
JPS5951269A (ja) 1984-03-24
PT77125B (en) 1986-01-24
US4460598A (en) 1984-07-17
GR78654B (da) 1984-09-27
DE3228271A1 (de) 1984-02-02
DK346783D0 (da) 1983-07-28
IE55485B1 (en) 1990-09-26
ATE25246T1 (de) 1987-02-15
ES524512A0 (es) 1984-04-16
NO160579C (no) 1989-05-03
EP0104342B1 (de) 1987-01-28
JPH0456030B2 (da) 1992-09-07
FI79302B (fi) 1989-08-31
DK158723C (da) 1990-12-10
IE831483L (en) 1983-12-29
FI832730A (fi) 1984-01-30
NO160579B (no) 1989-01-23
EP0104342A1 (de) 1984-04-04
ZA834648B (en) 1984-03-28
ES8404332A1 (es) 1984-04-16
PT77125A (en) 1983-08-01
DE3369508D1 (en) 1987-03-05
FI79302C (fi) 1989-12-11
DK158723B (da) 1990-07-09
NO832630L (no) 1984-01-30

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