IL87385A - Process for isolating basic proteins from protein mixtures containing such basic proteins - Google Patents

Process for isolating basic proteins from protein mixtures containing such basic proteins

Info

Publication number
IL87385A
IL87385A IL87385A IL8738588A IL87385A IL 87385 A IL87385 A IL 87385A IL 87385 A IL87385 A IL 87385A IL 8738588 A IL8738588 A IL 8738588A IL 87385 A IL87385 A IL 87385A
Authority
IL
Israel
Prior art keywords
basic proteins
protein mixtures
mixtures containing
isolating
proteins
Prior art date
Application number
IL87385A
Other languages
English (en)
Other versions
IL87385A0 (en
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IL87385A0 publication Critical patent/IL87385A0/xx
Publication of IL87385A publication Critical patent/IL87385A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL87385A 1987-08-11 1988-08-09 Process for isolating basic proteins from protein mixtures containing such basic proteins IL87385A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873726655 DE3726655A1 (de) 1987-08-11 1987-08-11 Verfahren zur isolierung basischer proteine aus proteingemischen, welche solche basischen proteine enthalten

Publications (2)

Publication Number Publication Date
IL87385A0 IL87385A0 (en) 1989-01-31
IL87385A true IL87385A (en) 1993-08-18

Family

ID=6333496

Family Applications (1)

Application Number Title Priority Date Filing Date
IL87385A IL87385A (en) 1987-08-11 1988-08-09 Process for isolating basic proteins from protein mixtures containing such basic proteins

Country Status (19)

Country Link
US (1) US5101013A (xx)
EP (1) EP0305760B1 (xx)
JP (1) JP2587867B2 (xx)
KR (1) KR0129539B1 (xx)
AT (1) ATE96447T1 (xx)
AU (1) AU609170B2 (xx)
CA (1) CA1340237C (xx)
DE (2) DE3726655A1 (xx)
DK (1) DK173502B1 (xx)
ES (1) ES2047007T3 (xx)
FI (1) FI91875C (xx)
HU (1) HU198218B (xx)
IE (1) IE61557B1 (xx)
IL (1) IL87385A (xx)
NO (1) NO175004C (xx)
NZ (1) NZ225746A (xx)
PH (1) PH26874A (xx)
PT (1) PT88230B (xx)
ZA (1) ZA885871B (xx)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0600372B1 (de) 1992-12-02 1997-02-05 Hoechst Aktiengesellschaft Verfahren zur Gewinnung von Proinsulin mit korrekt verbundenen Cystinbrücken
PT821006E (pt) 1996-07-26 2004-09-30 Aventis Pharma Gmbh Derivados de insulina com ligacao a zinco aumentada
DE19652713C2 (de) * 1996-12-18 2001-11-22 Aventis Pharma Gmbh Verfahren zur Reinigung von Insulin und Insulinderivaten durch Chromatographie an stark saurem Kationenaustauscher
KR100341297B1 (ko) * 1997-03-29 2002-11-16 주식회사종근당 재조합활성형프로인슐린의분리.정제방법
DE19726167B4 (de) 1997-06-20 2008-01-24 Sanofi-Aventis Deutschland Gmbh Insulin, Verfahren zu seiner Herstellung und es enthaltende pharmazeutische Zubereitung
DE19825447A1 (de) 1998-06-06 1999-12-09 Hoechst Marion Roussel De Gmbh Neue Insulinanaloga mit erhöhter Zinkbildung
US6444788B1 (en) 1999-03-15 2002-09-03 Novo Nordisk A/S Ion exchange chromatography of GLP-1, analogs and derivatives thereof
US6451987B1 (en) * 1999-03-15 2002-09-17 Novo Nordisk A/S Ion exchange chromatography of proteins and peptides
JP4732590B2 (ja) * 1999-03-15 2011-07-27 ノボ ノルディスク アクティーゼルスカブ Ｇｌｐ−１及び近縁ペプチドのイオン交換クロマトグラフィー分離
DE10114178A1 (de) 2001-03-23 2002-10-10 Aventis Pharma Gmbh Zinkfreie und zinkarme Insulinzubereitungen mit verbesserter Stabilität
DE10227232A1 (de) 2002-06-18 2004-01-15 Aventis Pharma Deutschland Gmbh Saure Insulinzubereitungen mit verbesserter Stabilität
DE10235168A1 (de) 2002-08-01 2004-02-12 Aventis Pharma Deutschland Gmbh Verfahren zur Reinigung von Preproinsulin
US7193035B2 (en) * 2002-10-29 2007-03-20 Sanofi-Aventis Deutschland Gmbh Crystals of insulin analogs and processes for their preparation
SE0300791D0 (sv) * 2003-03-20 2003-03-20 Amersham Biosciences Ab Use of ph-responsive polymers
DE602004023626D1 (de) * 2003-08-21 2009-11-26 Novo Nordisk As Trennung von polypeptiden mit einer racemisierten aminosäure
JP4984161B2 (ja) * 2005-08-04 2012-07-25 東洋製罐株式会社 プラスチックボトル殺菌方法
CA2740685C (en) 2008-10-17 2018-09-11 Sanofi-Aventis Deutschland Gmbh Combination of an insulin and a glp-1 agonist
FR2947818B1 (fr) * 2009-07-09 2011-07-29 Inst Superieur Des Sciences Agronomiques Agroalimentaires Horticoles Et Du Paysage Agro Campus Ouest Utilisation d'un coproduit issu d'un procede d'extraction du lysozyme a partir de blanc d'oeuf, pour l'obtention d'au moins une proteine basique de blanc d'oeuf
AU2010317995B2 (en) 2009-11-13 2014-04-17 Sanofi-Aventis Deutschland Gmbh Pharmaceutical composition comprising a GLP-1 agonist, an insulin, and methionine
JP5973918B2 (ja) 2009-11-13 2016-08-23 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Ｇｌｐ−１アゴニスト及びメチオニンを含む薬学的組成物
JP6199186B2 (ja) 2010-08-30 2017-09-20 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング ２型糖尿病の治療用の医薬の製造のためのａｖｅ００１０の使用
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
RU2650616C2 (ru) 2011-08-29 2018-04-16 Санофи-Авентис Дойчланд Гмбх Фармацевтическая комбинация для применения при гликемическом контроле у пациентов с сахарным диабетом 2 типа
TWI559929B (en) 2011-09-01 2016-12-01 Sanofi Aventis Deutschland Pharmaceutical composition for use in the treatment of a neurodegenerative disease
EP2748181B1 (en) 2011-09-30 2016-03-30 GE Healthcare BioProcess R&D AB Method for purification of cleaved pro-insulin
WO2014099577A1 (en) 2012-12-17 2014-06-26 Merck Sharp & Dohme Corp. Process for purifying insulin and analogues thereof
EP3116531B1 (en) 2014-03-14 2021-10-20 Merck Sharp & Dohme Corp. Purifying insulin using cation exchange and reverse phase chromatography in the presence of an organic modifier and elevated temperature
HRP20230470T1 (hr) 2014-12-12 2023-07-21 Sanofi-Aventis Deutschland Gmbh Formulacija fiksnog omjera inzulin glargin/liksisenatid
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患之治療
EP3581578A4 (en) * 2017-02-10 2020-04-22 Mitsubishi Chemical Corporation RELEASE AGENT FOR PURIFYING HUMAN INSULIN AND METHOD FOR PURIFYING HUMAN INSULIN

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2629568C3 (de) * 1976-07-01 1981-09-10 Hoechst Ag, 6000 Frankfurt Verfahren zur Reinigung von Insulin, seinen Analogen und Derivaten
NL7713966A (nl) * 1976-12-27 1978-06-29 Univ Minnesota Werkwijze voor het behandelen van insuline.
DK311477A (da) * 1977-07-08 1979-01-09 Leo Lab Fremgangsmaade ved fremstilling af rent insulin
US4459226A (en) * 1982-02-26 1984-07-10 Eli Lilly And Company Process for recovering insulin
DD247684A1 (de) * 1983-04-14 1987-07-15 Ulrich Krabiell Verfahren zur isolierung von insulinderivaten
ATE220101T1 (de) * 1983-04-25 2002-07-15 Chiron Corp Hybrid-dns-synthesis von reifen insulinähnlichen wachstumsfaktoren
DE3440988A1 (de) * 1984-11-09 1986-07-10 Hoechst Ag, 6230 Frankfurt Verfahren zur spaltung von peptiden und proteinen an der methionyl-bindung
DE3511269A1 (de) * 1985-04-12 1986-10-09 Veb Berlin-Chemie, Ddr 1199 Berlin Verfahren zur reinigung von insulin
JPS6379591A (ja) * 1986-09-22 1988-04-09 Mitsui Toatsu Chem Inc ｔＰＡの精製方法
AU607988B2 (en) * 1987-04-21 1991-03-21 Southern Cross Biotech Pty Ltd. Production of proteins in active forms
DE68919647T2 (de) * 1988-10-26 1995-05-11 American Cyanamid Co Verfahren zur Verringerung des Aggregatinhaltes in Wachstumshormonen gleichenden Stoffen.

Also Published As

Publication number Publication date
DK173502B1 (da) 2001-01-08
IL87385A0 (en) 1989-01-31
DK447688D0 (da) 1988-08-10
EP0305760B1 (de) 1993-10-27
FI883708A (fi) 1989-02-12
PT88230A (pt) 1989-06-30
NO175004B (no) 1994-05-09
ATE96447T1 (de) 1993-11-15
CA1340237C (en) 1998-12-15
EP0305760A2 (de) 1989-03-08
DE3726655A1 (de) 1989-02-23
ZA885871B (en) 1989-04-26
AU2059188A (en) 1989-02-16
JPS6486896A (en) 1989-03-31
NO883554D0 (no) 1988-08-10
IE882441L (en) 1989-02-11
IE61557B1 (en) 1994-11-16
FI883708A0 (fi) 1988-08-09
FI91875C (fi) 1994-08-25
NO883554L (no) 1989-02-13
KR890003799A (ko) 1989-04-18
HU198218B (en) 1989-08-28
US5101013A (en) 1992-03-31
AU609170B2 (en) 1991-04-26
DK447688A (da) 1989-02-12
HUT47958A (en) 1989-04-28
PH26874A (en) 1992-11-16
PT88230B (pt) 1995-03-01
FI91875B (fi) 1994-05-13
DE3885214D1 (de) 1993-12-02
NZ225746A (en) 1990-11-27
ES2047007T3 (es) 1994-02-16
JP2587867B2 (ja) 1997-03-05
EP0305760A3 (en) 1990-06-06
NO175004C (no) 1994-08-17
KR0129539B1 (ko) 1998-04-04

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