NO339495B1 - Trisyklisk benzopyranforbindelse - Google Patents

Trisyklisk benzopyranforbindelse Download PDF

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Publication number
NO339495B1
NO339495B1 NO20064819A NO20064819A NO339495B1 NO 339495 B1 NO339495 B1 NO 339495B1 NO 20064819 A NO20064819 A NO 20064819A NO 20064819 A NO20064819 A NO 20064819A NO 339495 B1 NO339495 B1 NO 339495B1
Authority
NO
Norway
Prior art keywords
dihydro
amino
pyrano
group
trimethyl
Prior art date
Application number
NO20064819A
Other languages
English (en)
Norwegian (no)
Other versions
NO20064819L (no
Inventor
Kazuhiko Ohrai
Yukihiro Shigeta
Tomoyuki Matsuda
Osamu Uesugi
Takumi Okada
Original Assignee
Nissan Chemical Ind Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nissan Chemical Ind Ltd filed Critical Nissan Chemical Ind Ltd
Publication of NO20064819L publication Critical patent/NO20064819L/no
Publication of NO339495B1 publication Critical patent/NO339495B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D515/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D515/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D515/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Dental Preparations (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO20064819A 2004-03-23 2006-10-23 Trisyklisk benzopyranforbindelse NO339495B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2004084605 2004-03-23
PCT/JP2005/006004 WO2005090357A1 (en) 2004-03-23 2005-03-23 Tricyclic benzopyran compound as anti-arrhythmic agents

Publications (2)

Publication Number Publication Date
NO20064819L NO20064819L (no) 2006-10-23
NO339495B1 true NO339495B1 (no) 2016-12-19

Family

ID=34962589

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20064819A NO339495B1 (no) 2004-03-23 2006-10-23 Trisyklisk benzopyranforbindelse

Country Status (30)

Country Link
US (2) US7652008B2 (cg-RX-API-DMAC7.html)
EP (1) EP1732929B1 (cg-RX-API-DMAC7.html)
JP (1) JP4840594B2 (cg-RX-API-DMAC7.html)
KR (2) KR101019402B1 (cg-RX-API-DMAC7.html)
CN (3) CN102190661B (cg-RX-API-DMAC7.html)
AT (1) ATE485299T1 (cg-RX-API-DMAC7.html)
AU (2) AU2005223612B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0508768A (cg-RX-API-DMAC7.html)
CA (1) CA2558139C (cg-RX-API-DMAC7.html)
CY (1) CY1111250T1 (cg-RX-API-DMAC7.html)
CZ (1) CZ2006598A3 (cg-RX-API-DMAC7.html)
DE (1) DE602005024245D1 (cg-RX-API-DMAC7.html)
DK (1) DK1732929T3 (cg-RX-API-DMAC7.html)
EG (1) EG27163A (cg-RX-API-DMAC7.html)
ES (1) ES2353021T3 (cg-RX-API-DMAC7.html)
HR (1) HRP20110005T1 (cg-RX-API-DMAC7.html)
IL (1) IL177950A (cg-RX-API-DMAC7.html)
MX (1) MXPA06010880A (cg-RX-API-DMAC7.html)
NO (1) NO339495B1 (cg-RX-API-DMAC7.html)
NZ (2) NZ549570A (cg-RX-API-DMAC7.html)
PL (1) PL1732929T3 (cg-RX-API-DMAC7.html)
PT (1) PT1732929E (cg-RX-API-DMAC7.html)
RS (1) RS51742B (cg-RX-API-DMAC7.html)
RU (1) RU2380370C2 (cg-RX-API-DMAC7.html)
SI (1) SI1732929T1 (cg-RX-API-DMAC7.html)
SK (1) SK287994B6 (cg-RX-API-DMAC7.html)
TW (1) TWI352704B (cg-RX-API-DMAC7.html)
UA (1) UA91189C2 (cg-RX-API-DMAC7.html)
WO (1) WO2005090357A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA200607388B (cg-RX-API-DMAC7.html)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4840594B2 (ja) * 2004-03-23 2011-12-21 日産化学工業株式会社 抗不整脈薬としての３環性ベンゾピラン化合物
US8394974B2 (en) 2006-03-10 2013-03-12 Nissan Chemical Industries, Ltd. Process for producing optically active chromene oxide compound
WO2010018867A1 (ja) * 2008-08-14 2010-02-18 日産化学工業株式会社 ジ置換ベンゾピラン化合物
AR076524A1 (es) * 2009-04-30 2011-06-15 Nissan Chemical Ind Ltd Forma cristalina de un compuesto de benzopirano triciclico y metodo de produccion de la misma
PT2445502T (pt) 2009-06-25 2017-09-22 Alkermes Pharma Ireland Ltd Compostos heterocíclicos para o tratamento de distúrbios neurológicos e psicológicos
US9738654B2 (en) 2012-09-27 2017-08-22 Nissan Chemical Industries, Ltd. Method for producing nitrogen-containing heterocyclic N-oxide compound
CN104507949B (zh) * 2012-09-27 2017-07-28 日产化学工业株式会社 高纯度的含氮杂环化合物的制造方法
CN105377826A (zh) * 2013-07-25 2016-03-02 日产化学工业株式会社 杂环化合物的制造方法
CN110177796B (zh) * 2017-01-06 2022-04-08 阿斯克里斯有限公司 喹啉酮衍生物及其用于预防或治疗变应性疾病的药物组合物
AU2019230014B2 (en) 2018-03-05 2024-11-28 Alkermes Pharma Ireland Limited Aripiprazole dosing strategy
CN108727261B (zh) * 2018-06-21 2021-09-24 济南大学 一种硝基取代喹那啶的制备方法
CN113543849B (zh) * 2018-12-28 2025-03-21 国立大学法人大阪大学 遗传性缓慢性心律失常治疗药
RU2754610C1 (ru) * 2020-04-14 2021-09-03 Георгий Викторович ТЕЦ Препарат для лечения заболеваний, вызванных бактериями
JP7733887B2 (ja) * 2020-06-26 2025-09-04 国立大学法人大阪大学 薬剤誘発性徐脈および徐脈性不整脈治療薬

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0327127A1 (en) * 1988-02-03 1989-08-09 Nissan Chemical Industries Ltd. Pyranobenzoxadiazole derivatives, preparation, use and compositions comprising them
JPH024791A (ja) * 1988-06-23 1990-01-09 Nissan Chem Ind Ltd ピラノベンゾトリアゾール誘導体
EP0409165A2 (en) * 1989-07-17 1991-01-23 Nissan Chemical Industries Ltd. Process for the optical resolution of pyranobenzoxadiazole compounds
EP0488107A2 (en) * 1990-11-26 1992-06-03 E.R. SQUIBB & SONS, INC. Tricyclic benzodiazole analogs and their use in the treatment of cardiovascular disorders
WO1995034547A1 (en) * 1994-06-10 1995-12-21 Smithkline Beecham Plc C-4 amide substituted compounds and their use as therapeutic agents
EP0693283A1 (en) * 1993-04-02 1996-01-24 Nissan Chemical Industries, Limited Heart failure remedy

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZM7682A1 (en) 1981-09-25 1983-05-23 Beecham Group Plc Active compounds
JPS5867683U (ja) 1981-10-28 1983-05-09 株式会社ナムコ 歩行ロボツト
JP2876712B2 (ja) * 1989-07-17 1999-03-31 日産化学工業株式会社 光学活性ピラノベンゾオキサジアゾール誘導体
JPH07300414A (ja) * 1993-04-02 1995-11-14 Nissan Chem Ind Ltd 心不全治療薬
JP2734457B2 (ja) 1994-02-23 1998-03-30 日産化学工業株式会社 不斉エポキシ化反応
TW496866B (en) * 1996-05-15 2002-08-01 Hoechst Ag Sulfonamide-substituted chromans, processes for their preparation, their use as a medicament or a diagnostic, and medicament comprising them
WO1999062867A1 (fr) 1998-06-03 1999-12-09 Nissan Chemical Industries, Ltd. Derives d'indane
AU5444499A (en) 1998-09-01 2000-03-21 Nissan Chemical Industries Ltd. Benzoxazine derivatives
AU2830800A (en) 1999-03-25 2000-10-16 Nissan Chemical Industries Ltd. Chroman derivatives
WO2001021610A1 (en) 1999-09-17 2001-03-29 Nissan Chemical Industries, Ltd. Benzopyran derivative
US6555574B1 (en) 1999-09-24 2003-04-29 Nissan Chemical Industries, Ltd. 4-oxybenzopyran derivative
US6677371B1 (en) 1999-10-05 2004-01-13 Nissan Chemical Industries, Ltd. 4-oxybenzopyran derivative
TW589305B (en) 2001-02-14 2004-06-01 Nissan Chemical Ind Ltd 4-aminobenzopyran derivatives
IL159218A0 (en) 2001-06-25 2004-06-01 Nissan Chemical Ind Ltd Substituted benzopyran derivatives against arrhythmia
WO2003014113A1 (en) 2001-08-06 2003-02-20 Glenmark Pharmaceuticals Limited Novel benzopyran compounds and process for their preparation and use
JP4840594B2 (ja) * 2004-03-23 2011-12-21 日産化学工業株式会社 抗不整脈薬としての３環性ベンゾピラン化合物

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0327127A1 (en) * 1988-02-03 1989-08-09 Nissan Chemical Industries Ltd. Pyranobenzoxadiazole derivatives, preparation, use and compositions comprising them
JPH024791A (ja) * 1988-06-23 1990-01-09 Nissan Chem Ind Ltd ピラノベンゾトリアゾール誘導体
EP0409165A2 (en) * 1989-07-17 1991-01-23 Nissan Chemical Industries Ltd. Process for the optical resolution of pyranobenzoxadiazole compounds
EP0488107A2 (en) * 1990-11-26 1992-06-03 E.R. SQUIBB & SONS, INC. Tricyclic benzodiazole analogs and their use in the treatment of cardiovascular disorders
EP0693283A1 (en) * 1993-04-02 1996-01-24 Nissan Chemical Industries, Limited Heart failure remedy
WO1995034547A1 (en) * 1994-06-10 1995-12-21 Smithkline Beecham Plc C-4 amide substituted compounds and their use as therapeutic agents

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 7, no. 12, 1997, side 1573-1576, Dated: 01.01.0001 *

Also Published As

Publication number Publication date
DK1732929T3 (da) 2010-12-20
US20100069374A1 (en) 2010-03-18
NZ585606A (en) 2011-11-25
UA91189C2 (en) 2010-07-12
SK287994B6 (sk) 2012-09-03
PT1732929E (pt) 2010-12-21
CA2558139C (en) 2012-01-17
NZ549570A (en) 2010-08-27
HRP20110005T1 (hr) 2011-02-28
WO2005090357A1 (en) 2005-09-29
US7964623B2 (en) 2011-06-21
CN1934116B (zh) 2012-10-10
TW200600509A (en) 2006-01-01
ATE485299T1 (de) 2010-11-15
SK50792006A3 (sk) 2007-09-06
RS51742B (sr) 2011-10-31
KR101019402B1 (ko) 2011-03-07
KR20100130249A (ko) 2010-12-10
AU2010202900B2 (en) 2011-10-27
AU2005223612A1 (en) 2005-09-29
IL177950A (en) 2013-04-30
AU2005223612B2 (en) 2010-06-24
KR101085979B1 (ko) 2011-11-22
BRPI0508768A (pt) 2007-02-27
MXPA06010880A (es) 2006-12-15
KR20070009638A (ko) 2007-01-18
CN102190661B (zh) 2013-07-31
CN101429200B (zh) 2012-05-30
CY1111250T1 (el) 2015-06-11
JP2007530436A (ja) 2007-11-01
SI1732929T1 (sl) 2010-12-31
NO20064819L (no) 2006-10-23
EP1732929B1 (en) 2010-10-20
ES2353021T3 (es) 2011-02-24
AU2010202900A1 (en) 2010-07-29
CA2558139A1 (en) 2005-09-29
EP1732929A1 (en) 2006-12-20
CN1934116A (zh) 2007-03-21
IL177950A0 (en) 2006-12-31
EG27163A (en) 2015-08-24
JP4840594B2 (ja) 2011-12-21
PL1732929T3 (pl) 2011-04-29
DE602005024245D1 (de) 2010-12-02
CZ2006598A3 (cs) 2006-11-15
RU2006137284A (ru) 2008-04-27
US7652008B2 (en) 2010-01-26
HK1099299A1 (en) 2007-08-10
TWI352704B (en) 2011-11-21
CN102190661A (zh) 2011-09-21
CN101429200A (zh) 2009-05-13
US20080004262A1 (en) 2008-01-03
RU2380370C2 (ru) 2010-01-27
ZA200607388B (en) 2008-07-30

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