SI1732929T1 - Tricikliäśna benzopiranska spojina kot antiaritmiäśna sredstva - Google Patents

Tricikliäśna benzopiranska spojina kot antiaritmiäśna sredstva

Info

Publication number
SI1732929T1
SI1732929T1 SI200531171T SI200531171T SI1732929T1 SI 1732929 T1 SI1732929 T1 SI 1732929T1 SI 200531171 T SI200531171 T SI 200531171T SI 200531171 T SI200531171 T SI 200531171T SI 1732929 T1 SI1732929 T1 SI 1732929T1
Authority
SI
Slovenia
Prior art keywords
group
hydrogen atom
ring
atom
bond
Prior art date
Application number
SI200531171T
Other languages
English (en)
Inventor
Kazuhiko Ohrai
Yukihiro Shigeta
Osamu Uesugi
Takumi Okada
Tomoyuki Matsuda
Original Assignee
Nissan Chemical Ind Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nissan Chemical Ind Ltd filed Critical Nissan Chemical Ind Ltd
Publication of SI1732929T1 publication Critical patent/SI1732929T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D515/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D515/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D515/04Ortho-condensed systems
SI200531171T 2004-03-23 2005-03-23 Tricikliäśna benzopiranska spojina kot antiaritmiäśna sredstva SI1732929T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2004084605 2004-03-23
EP05727581A EP1732929B1 (en) 2004-03-23 2005-03-23 Tricyclic benzopyran compound as anti-arrhythmic agents
PCT/JP2005/006004 WO2005090357A1 (en) 2004-03-23 2005-03-23 Tricyclic benzopyran compound as anti-arrhythmic agents

Publications (1)

Publication Number Publication Date
SI1732929T1 true SI1732929T1 (sl) 2010-12-31

Family

ID=34962589

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200531171T SI1732929T1 (sl) 2004-03-23 2005-03-23 Tricikliäśna benzopiranska spojina kot antiaritmiäśna sredstva

Country Status (31)

Country Link
US (2) US7652008B2 (sl)
EP (1) EP1732929B1 (sl)
JP (1) JP4840594B2 (sl)
KR (2) KR101085979B1 (sl)
CN (3) CN1934116B (sl)
AT (1) ATE485299T1 (sl)
AU (2) AU2005223612B2 (sl)
BR (1) BRPI0508768A (sl)
CA (1) CA2558139C (sl)
CY (1) CY1111250T1 (sl)
CZ (1) CZ2006598A3 (sl)
DE (1) DE602005024245D1 (sl)
DK (1) DK1732929T3 (sl)
EG (1) EG27163A (sl)
ES (1) ES2353021T3 (sl)
HK (1) HK1099299A1 (sl)
HR (1) HRP20110005T1 (sl)
IL (1) IL177950A (sl)
MX (1) MXPA06010880A (sl)
NO (1) NO339495B1 (sl)
NZ (2) NZ549570A (sl)
PL (1) PL1732929T3 (sl)
PT (1) PT1732929E (sl)
RS (1) RS51742B (sl)
RU (1) RU2380370C2 (sl)
SI (1) SI1732929T1 (sl)
SK (1) SK287994B6 (sl)
TW (1) TWI352704B (sl)
UA (1) UA91189C2 (sl)
WO (1) WO2005090357A1 (sl)
ZA (1) ZA200607388B (sl)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4840594B2 (ja) * 2004-03-23 2011-12-21 日産化学工業株式会社 抗不整脈薬としての3環性ベンゾピラン化合物
WO2007105658A1 (ja) 2006-03-10 2007-09-20 Nissan Chemical Industries, Ltd. 光学活性クロメンオキシド化合物の製造方法
WO2010018867A1 (ja) * 2008-08-14 2010-02-18 日産化学工業株式会社 ジ置換ベンゾピラン化合物
EP2426133B1 (en) * 2009-04-30 2015-12-16 Nissan Chemical Industries, Ltd. Novel crystal forms of tricyclic benzopyran compound and processes for producing same
LT2445502T (lt) 2009-06-25 2017-09-25 Alkermes Pharma Ireland Limited Heterocikliniai junginiai, skirti neurologinių ir fiziologinių susirgimų gydymui
US9464095B2 (en) 2012-09-27 2016-10-11 Nissan Chemical Industries, Ltd. Production method of high-purity nitrogen-containing heterocyclic compound
CN104507948B (zh) * 2012-09-27 2017-05-03 日产化学工业株式会社 含氮杂环n‑氧化物化合物的制造方法
US20160168161A1 (en) * 2013-07-25 2016-06-16 Nissan Chemical Industies, Ltd. Method for producing heterocyclic compound
EP3567044A4 (en) 2017-01-06 2020-06-10 Korea University Research and Business Foundation, Sejong Campus INNOVATIVE CHINOLINONE DERIVATIVE AND PHARMACEUTICAL COMPOSITION FOR THE PREVENTION OR TREATMENT OF ALLERGIC DISEASES LIKE ASTHMA OR ATOPIA THEREFORE AS AN ACTIVE SUBSTANCE
EP3761983A1 (en) 2018-03-05 2021-01-13 Alkermes Pharma Ireland Limited Aripiprazole dosing strategy
CN108727261B (zh) * 2018-06-21 2021-09-24 济南大学 一种硝基取代喹那啶的制备方法
US20220071951A1 (en) * 2018-12-28 2022-03-10 Osaka University Therapeutic agent for inherited bradyarrhythmia
RU2754610C1 (ru) * 2020-04-14 2021-09-03 Георгий Викторович ТЕЦ Препарат для лечения заболеваний, вызванных бактериями
EP4173623A1 (en) * 2020-06-26 2023-05-03 Osaka University Therapeutic agent for drug-induced bradycardia and bradyarrhythmia

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZM7682A1 (en) 1981-09-25 1983-05-23 Beecham Group Plc Active compounds
JPS5867683U (ja) 1981-10-28 1983-05-09 株式会社ナムコ 歩行ロボツト
JPH0699439B2 (ja) * 1988-02-03 1994-12-07 日産化学工業株式会社 ピラノベンゾオキサジアゾール誘導体
JP2658198B2 (ja) 1988-06-23 1997-09-30 日産化学工業株式会社 ピラノベンゾトリアゾール誘導体
US5097037A (en) * 1989-07-17 1992-03-17 Nissan Chemical Industries, Ltd. Process for the optical resolution of pyranobenzoxadiazole compounds
JP2876712B2 (ja) * 1989-07-17 1999-03-31 日産化学工業株式会社 光学活性ピラノベンゾオキサジアゾール誘導体
US5164509A (en) * 1990-11-26 1992-11-17 E. R. Squibb & Sons, Inc. Benzodiazolo analogs
JPH07300414A (ja) * 1993-04-02 1995-11-14 Nissan Chem Ind Ltd 心不全治療薬
US5919806A (en) * 1993-04-02 1999-07-06 Nissan Chemical Industries, Ltd. Medicines for cardiac insufficiency
JP2734457B2 (ja) 1994-02-23 1998-03-30 日産化学工業株式会社 不斉エポキシ化反応
JPH10501256A (ja) * 1994-06-10 1998-02-03 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー C−4アミド置換化合物およびその治療剤としての使用
EP0807629B1 (de) * 1996-05-15 2004-03-03 Aventis Pharma Deutschland GmbH Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
CA2334412A1 (en) 1998-06-03 1999-12-09 Nissan Chemical Industries, Ltd. Indan derivatives
AU5444499A (en) 1998-09-01 2000-03-21 Nissan Chemical Industries Ltd. Benzoxazine derivatives
WO2000058300A1 (fr) 1999-03-25 2000-10-05 Nissan Chemical Industries, Ltd. Derives du chroman
CZ2002802A3 (cs) 1999-09-17 2003-02-12 Nissan Chemical Industries, Ltd. Benzopyranové deriváty
AU7319800A (en) 1999-09-24 2001-04-24 Nissan Chemical Industries Ltd. 4-oxybenzopyran derivative
EP1218367A1 (en) 1999-10-05 2002-07-03 Nissan Chemical Industries, Ltd. 4-oxybenzopyran derivative
TW589305B (en) 2001-02-14 2004-06-01 Nissan Chemical Ind Ltd 4-aminobenzopyran derivatives
SK15782003A3 (sk) 2001-06-25 2004-05-04 Nissan Chemical Industries, Ltd. Substituované benzopyránové deriváty proti arytmiám
WO2003014113A1 (en) 2001-08-06 2003-02-20 Glenmark Pharmaceuticals Limited Novel benzopyran compounds and process for their preparation and use
JP4840594B2 (ja) * 2004-03-23 2011-12-21 日産化学工業株式会社 抗不整脈薬としての3環性ベンゾピラン化合物

Also Published As

Publication number Publication date
RS51742B (en) 2011-10-31
IL177950A0 (en) 2006-12-31
HK1099299A1 (en) 2007-08-10
KR20100130249A (ko) 2010-12-10
DE602005024245D1 (de) 2010-12-02
KR101085979B1 (ko) 2011-11-22
NO20064819L (no) 2006-10-23
US20100069374A1 (en) 2010-03-18
EG27163A (en) 2015-08-24
US7652008B2 (en) 2010-01-26
SK287994B6 (sk) 2012-09-03
SK50792006A3 (sk) 2007-09-06
KR101019402B1 (ko) 2011-03-07
TWI352704B (en) 2011-11-21
KR20070009638A (ko) 2007-01-18
JP4840594B2 (ja) 2011-12-21
IL177950A (en) 2013-04-30
CZ2006598A3 (cs) 2006-11-15
NZ549570A (en) 2010-08-27
MXPA06010880A (es) 2006-12-15
AU2005223612B2 (en) 2010-06-24
BRPI0508768A (pt) 2007-02-27
CN1934116A (zh) 2007-03-21
HRP20110005T1 (hr) 2011-02-28
PT1732929E (pt) 2010-12-21
CY1111250T1 (el) 2015-06-11
ES2353021T3 (es) 2011-02-24
AU2010202900B2 (en) 2011-10-27
PL1732929T3 (pl) 2011-04-29
ZA200607388B (en) 2008-07-30
AU2005223612A1 (en) 2005-09-29
NO339495B1 (no) 2016-12-19
EP1732929A1 (en) 2006-12-20
EP1732929B1 (en) 2010-10-20
ATE485299T1 (de) 2010-11-15
RU2006137284A (ru) 2008-04-27
WO2005090357A1 (en) 2005-09-29
US20080004262A1 (en) 2008-01-03
UA91189C2 (en) 2010-07-12
AU2010202900A1 (en) 2010-07-29
CA2558139A1 (en) 2005-09-29
CA2558139C (en) 2012-01-17
NZ585606A (en) 2011-11-25
CN1934116B (zh) 2012-10-10
TW200600509A (en) 2006-01-01
DK1732929T3 (da) 2010-12-20
CN102190661B (zh) 2013-07-31
CN101429200A (zh) 2009-05-13
CN102190661A (zh) 2011-09-21
JP2007530436A (ja) 2007-11-01
RU2380370C2 (ru) 2010-01-27
CN101429200B (zh) 2012-05-30
US7964623B2 (en) 2011-06-21

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