NO20064819L - Trisyklisk benzopyranforbindelse - Google Patents
Trisyklisk benzopyranforbindelseInfo
- Publication number
- NO20064819L NO20064819L NO20064819A NO20064819A NO20064819L NO 20064819 L NO20064819 L NO 20064819L NO 20064819 A NO20064819 A NO 20064819A NO 20064819 A NO20064819 A NO 20064819A NO 20064819 L NO20064819 L NO 20064819L
- Authority
- NO
- Norway
- Prior art keywords
- group
- hydrogen atom
- ring
- atom
- bond
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D515/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D515/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D515/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrane Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
- Dental Preparations (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Denne oppfinnelsen vedrører benzopyranderivater med formel (I) eller (II), eller farmasøytisk akseptable salter derav hvori R' og R2 uavhengig av hverandre er hydrogenatom, Cl-6 alkylgruppe eller C6-14 arylgruppe, R3 er hydrogenatom eller Cl-6 alkylkarbonyloksygruppe, eller sammen med R4 danner en binding, R4 er hydrogenatom, eller sammen med R3 danner en binding, m er et heltall fra 0 til 4, n er et heltall fra 0 til 4, V er en enkeltbinding, CR7R8, NR9, 0, S, SO eller S02, R5 er hydrogenatom eller Cl-6alkylgruppe, R6 er hydrogenatom, C l-6 alkylgruppe, C3-8 cykloalkylgruppe, C3-8cykloalkenylgruppe, aminogruppe, Cl-6 alkylaminogruppe, diC l-6 alkylaminogruppe, C6-14 arylaminogruppe, C2-9 heteroarylaminogruppe, C6-14 arylgruppe, C2-9 heteroarylgruppe eller C2-9 heterocyklylgruppe, A er 5-, 6- eller 7-leddet ring fusjonert med benzenring, som komponentatomer i ringen kan oksygenatom, nitrogenatom eller svovelatom være inkludert i et antall av 1 til 3 alene eller i kombinasjon derav, antallet av umettede bindinger i ringen er 1, 2 eller 3 inklusive en umettet binding av benzenringen som fusjoneres, karbonatomer som utgjør ringen kan være karbonyl eller tiokarbonyl. Disse forbindelsene er anvendbare som et anti-arytmisk middel.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004084605 | 2004-03-23 | ||
| PCT/JP2005/006004 WO2005090357A1 (en) | 2004-03-23 | 2005-03-23 | Tricyclic benzopyran compound as anti-arrhythmic agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20064819L true NO20064819L (no) | 2006-10-23 |
| NO339495B1 NO339495B1 (no) | 2016-12-19 |
Family
ID=34962589
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20064819A NO339495B1 (no) | 2004-03-23 | 2006-10-23 | Trisyklisk benzopyranforbindelse |
Country Status (31)
| Country | Link |
|---|---|
| US (2) | US7652008B2 (no) |
| EP (1) | EP1732929B1 (no) |
| JP (1) | JP4840594B2 (no) |
| KR (2) | KR101085979B1 (no) |
| CN (3) | CN102190661B (no) |
| AT (1) | ATE485299T1 (no) |
| AU (2) | AU2005223612B2 (no) |
| BR (1) | BRPI0508768A (no) |
| CA (1) | CA2558139C (no) |
| CY (1) | CY1111250T1 (no) |
| CZ (1) | CZ2006598A3 (no) |
| DE (1) | DE602005024245D1 (no) |
| DK (1) | DK1732929T3 (no) |
| EG (1) | EG27163A (no) |
| ES (1) | ES2353021T3 (no) |
| HK (1) | HK1099299A1 (no) |
| HR (1) | HRP20110005T1 (no) |
| IL (1) | IL177950A (no) |
| MX (1) | MXPA06010880A (no) |
| NO (1) | NO339495B1 (no) |
| NZ (2) | NZ585606A (no) |
| PL (1) | PL1732929T3 (no) |
| PT (1) | PT1732929E (no) |
| RS (1) | RS51742B (no) |
| RU (1) | RU2380370C2 (no) |
| SI (1) | SI1732929T1 (no) |
| SK (1) | SK287994B6 (no) |
| TW (1) | TWI352704B (no) |
| UA (1) | UA91189C2 (no) |
| WO (1) | WO2005090357A1 (no) |
| ZA (1) | ZA200607388B (no) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2005223612B2 (en) * | 2004-03-23 | 2010-06-24 | Nissan Chemical Industries, Ltd. | Tricyclic benzopyran compound as anti-arrhythmic agents |
| KR20080112290A (ko) | 2006-03-10 | 2008-12-24 | 닛산 가가쿠 고교 가부시키 가이샤 | 광학 활성 크로멘 옥사이드화합물의 제조 방법 |
| TW201022223A (en) * | 2008-08-14 | 2010-06-16 | Nissan Chemical Ind Ltd | Di-substituted benzopyrane compound |
| JP5664870B2 (ja) * | 2009-04-30 | 2015-02-04 | 日産化学工業株式会社 | ３環性ベンゾピラン化合物の新規な結晶形態及びその製造方法 |
| EP3309151A1 (en) | 2009-06-25 | 2018-04-18 | Alkermes Pharma Ireland Limited | Heterocyclic compounds for the treatment of neurological and psychological disorders |
| CN104507948B (zh) * | 2012-09-27 | 2017-05-03 | 日产化学工业株式会社 | 含氮杂环n‑氧化物化合物的制造方法 |
| IN2015DN03012A (no) * | 2012-09-27 | 2015-10-02 | Nissan Chemical Ind Ltd | |
| JPWO2015012271A1 (ja) * | 2013-07-25 | 2017-03-02 | 日産化学工業株式会社 | 複素環化合物の製造方法 |
| KR102009756B1 (ko) * | 2017-01-06 | 2019-08-12 | 고려대학교 세종산학협력단 | 신규한 퀴놀리논 유도체 및 이를 유효성분으로 포함하는 천식 또는 아토피 등의 알러지성 질환의 예방 또는 치료용 약학 조성물 |
| CA3092335A1 (en) | 2018-03-05 | 2019-09-12 | Alkermes Pharma Ireland Limited | Aripiprazole dosing strategy |
| CN108727261B (zh) * | 2018-06-21 | 2021-09-24 | 济南大学 | 一种硝基取代喹那啶的制备方法 |
| EP3903882A4 (en) | 2018-12-28 | 2022-09-21 | Osaka University | THERAPEUTIC AGENT FOR INHERITED BRADYARRHYTHMIA |
| RU2754610C1 (ru) * | 2020-04-14 | 2021-09-03 | Георгий Викторович ТЕЦ | Препарат для лечения заболеваний, вызванных бактериями |
| JPWO2021261598A1 (no) * | 2020-06-26 | 2021-12-30 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZM7682A1 (en) | 1981-09-25 | 1983-05-23 | Beecham Group Plc | Active compounds |
| JPS5867683U (ja) | 1981-10-28 | 1983-05-09 | 株式会社ナムコ | 歩行ロボツト |
| JPH0699439B2 (ja) * | 1988-02-03 | 1994-12-07 | 日産化学工業株式会社 | ピラノベンゾオキサジアゾール誘導体 |
| JP2658198B2 (ja) * | 1988-06-23 | 1997-09-30 | 日産化学工業株式会社 | ピラノベンゾトリアゾール誘導体 |
| US5097037A (en) | 1989-07-17 | 1992-03-17 | Nissan Chemical Industries, Ltd. | Process for the optical resolution of pyranobenzoxadiazole compounds |
| JP2876712B2 (ja) * | 1989-07-17 | 1999-03-31 | 日産化学工業株式会社 | 光学活性ピラノベンゾオキサジアゾール誘導体 |
| US5164509A (en) * | 1990-11-26 | 1992-11-17 | E. R. Squibb & Sons, Inc. | Benzodiazolo analogs |
| TW384291B (en) | 1993-04-02 | 2000-03-11 | Nissan Chemical Ind Ltd | Compounds for reinforcing the contraction of cardiac muscles and reducing the rate of heart beats |
| JPH07300414A (ja) * | 1993-04-02 | 1995-11-14 | Nissan Chem Ind Ltd | 心不全治療薬 |
| JP2734457B2 (ja) | 1994-02-23 | 1998-03-30 | 日産化学工業株式会社 | 不斉エポキシ化反応 |
| DE69518322T2 (de) * | 1994-06-10 | 2001-02-15 | Smithkline Beecham Plc | C-4 amid substituierte verbindungen und deren verwendung als therapeutische mittel |
| SK283837B6 (sk) * | 1996-05-15 | 2004-03-02 | Hoechst Aktiengesellschaft | Chrómany, spôsob ich prípravy, liečivá, ktoré ich obsahujú, a ich použitie |
| DE69921815T2 (de) | 1998-06-03 | 2005-11-10 | Nissan Chemical Industries, Ltd. | Indanderivate |
| WO2000012492A1 (en) | 1998-09-01 | 2000-03-09 | Nissan Chemical Industries, Ltd. | Benzoxazine derivatives |
| AU2830800A (en) | 1999-03-25 | 2000-10-16 | Nissan Chemical Industries Ltd. | Chroman derivatives |
| CZ2002802A3 (cs) | 1999-09-17 | 2003-02-12 | Nissan Chemical Industries, Ltd. | Benzopyranové deriváty |
| US6555574B1 (en) | 1999-09-24 | 2003-04-29 | Nissan Chemical Industries, Ltd. | 4-oxybenzopyran derivative |
| US6677371B1 (en) | 1999-10-05 | 2004-01-13 | Nissan Chemical Industries, Ltd. | 4-oxybenzopyran derivative |
| TW589305B (en) | 2001-02-14 | 2004-06-01 | Nissan Chemical Ind Ltd | 4-aminobenzopyran derivatives |
| NZ529916A (en) | 2001-06-25 | 2005-04-29 | Nissan Chemical Ind Ltd | Substituted benzopyran derivatives against arrhythmia |
| WO2003014113A1 (en) | 2001-08-06 | 2003-02-20 | Glenmark Pharmaceuticals Limited | Novel benzopyran compounds and process for their preparation and use |
| AU2005223612B2 (en) * | 2004-03-23 | 2010-06-24 | Nissan Chemical Industries, Ltd. | Tricyclic benzopyran compound as anti-arrhythmic agents |
-
2005
- 2005-03-23 AU AU2005223612A patent/AU2005223612B2/en not_active Ceased
- 2005-03-23 EP EP05727581A patent/EP1732929B1/en active Active
- 2005-03-23 MX MXPA06010880A patent/MXPA06010880A/es active IP Right Grant
- 2005-03-23 BR BRPI0508768-6A patent/BRPI0508768A/pt not_active Application Discontinuation
- 2005-03-23 RU RU2006137284/04A patent/RU2380370C2/ru not_active IP Right Cessation
- 2005-03-23 ES ES05727581T patent/ES2353021T3/es active Active
- 2005-03-23 CN CN2011100751168A patent/CN102190661B/zh not_active Expired - Fee Related
- 2005-03-23 CN CN2005800090295A patent/CN1934116B/zh active Active
- 2005-03-23 SK SK5079-2006A patent/SK287994B6/sk not_active IP Right Cessation
- 2005-03-23 CZ CZ20060598A patent/CZ2006598A3/cs unknown
- 2005-03-23 CN CN2008101707921A patent/CN101429200B/zh not_active Expired - Fee Related
- 2005-03-23 WO PCT/JP2005/006004 patent/WO2005090357A1/en active Application Filing
- 2005-03-23 NZ NZ585606A patent/NZ585606A/en unknown
- 2005-03-23 KR KR1020107027058A patent/KR101085979B1/ko active IP Right Grant
- 2005-03-23 US US10/590,975 patent/US7652008B2/en active Active
- 2005-03-23 CA CA2558139A patent/CA2558139C/en not_active Expired - Fee Related
- 2005-03-23 AT AT05727581T patent/ATE485299T1/de active
- 2005-03-23 DE DE602005024245T patent/DE602005024245D1/de active Active
- 2005-03-23 TW TW094108962A patent/TWI352704B/zh active
- 2005-03-23 NZ NZ549570A patent/NZ549570A/en unknown
- 2005-03-23 SI SI200531171T patent/SI1732929T1/sl unknown
- 2005-03-23 UA UAA200611101A patent/UA91189C2/ru unknown
- 2005-03-23 DK DK05727581.0T patent/DK1732929T3/da active
- 2005-03-23 PT PT05727581T patent/PT1732929E/pt unknown
- 2005-03-23 JP JP2006530022A patent/JP4840594B2/ja active Active
- 2005-03-23 RS RS20110028A patent/RS51742B/en unknown
- 2005-03-23 PL PL05727581T patent/PL1732929T3/pl unknown
- 2005-03-23 KR KR1020067021988A patent/KR101019402B1/ko active IP Right Grant
- 2005-03-23 ZA ZA200607388A patent/ZA200607388B/en unknown
-
2006
- 2006-09-02 EG EGNA2006000900 patent/EG27163A/xx active
- 2006-09-07 IL IL177950A patent/IL177950A/en not_active IP Right Cessation
- 2006-10-23 NO NO20064819A patent/NO339495B1/no not_active IP Right Cessation
-
2007
- 2007-06-15 HK HK07106502.1A patent/HK1099299A1/xx unknown
-
2009
- 2009-11-17 US US12/591,353 patent/US7964623B2/en not_active Expired - Fee Related
-
2010
- 2010-07-08 AU AU2010202900A patent/AU2010202900B2/en not_active Ceased
-
2011
- 2011-01-05 HR HR20110005T patent/HRP20110005T1/hr unknown
- 2011-01-19 CY CY20111100060T patent/CY1111250T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |