DE69518322T2 - C-4 amid substituierte verbindungen und deren verwendung als therapeutische mittel - Google Patents
C-4 amid substituierte verbindungen und deren verwendung als therapeutische mittelInfo
- Publication number
- DE69518322T2 DE69518322T2 DE69518322T DE69518322T DE69518322T2 DE 69518322 T2 DE69518322 T2 DE 69518322T2 DE 69518322 T DE69518322 T DE 69518322T DE 69518322 T DE69518322 T DE 69518322T DE 69518322 T2 DE69518322 T2 DE 69518322T2
- Authority
- DE
- Germany
- Prior art keywords
- amid
- therapeutic agent
- substituted compounds
- substituted
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9411636A GB9411636D0 (en) | 1994-06-10 | 1994-06-10 | Novel treatment |
GB9411797A GB9411797D0 (en) | 1994-06-13 | 1994-06-13 | Novel compounds |
PCT/EP1995/002249 WO1995034547A1 (en) | 1994-06-10 | 1995-06-09 | C-4 amide substituted compounds and their use as therapeutic agents |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69518322D1 DE69518322D1 (de) | 2000-09-14 |
DE69518322T2 true DE69518322T2 (de) | 2001-02-15 |
Family
ID=26305045
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69518322T Expired - Fee Related DE69518322T2 (de) | 1994-06-10 | 1995-06-09 | C-4 amid substituierte verbindungen und deren verwendung als therapeutische mittel |
Country Status (5)
Country | Link |
---|---|
US (1) | US5843989A (de) |
EP (1) | EP0764159B1 (de) |
JP (1) | JPH10501256A (de) |
DE (1) | DE69518322T2 (de) |
WO (1) | WO1995034547A1 (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9813949D0 (en) * | 1998-06-29 | 1998-08-26 | Smithkline Beecham Plc | Novel compounds |
DE60206505T2 (de) | 2001-06-25 | 2006-07-06 | Nissan Chemical Industries, Ltd. | Substituierte benzopyranderivate gegen arrhytmie |
EP1511734B1 (de) * | 2002-04-17 | 2010-06-23 | Cytokinetics, Inc. | Verbindungen, zusammensetzungen und verfahren |
WO2004006865A2 (en) * | 2002-07-17 | 2004-01-22 | Cytokinetics, Inc. | Compounds, compositions, and methods |
EP1554265A4 (de) * | 2002-09-13 | 2008-05-07 | Cytokinetics Inc | Verbindungen, zusammensetzungen und verfahren |
US20050165089A1 (en) * | 2003-10-06 | 2005-07-28 | Gustave Bergnes | Compounds, compositions and methods |
NZ585606A (en) * | 2004-03-23 | 2011-11-25 | Nissan Chemical Ind Ltd | Tricyclic benzopyran compound as anti-arrhythmic agents |
US7999107B2 (en) | 2007-01-31 | 2011-08-16 | Merck Sharp & Dohme Corp. | Substituted pyrano[2,3-B]pyridine derivatives as cannabinoid-1 receptor modulators |
CA2961894C (en) | 2014-09-19 | 2023-12-12 | Memorial Sloan-Kettering Cancer Center | Methods for treating brain metastatis using gap junction inhibitors |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1319772A (en) * | 1969-06-18 | 1973-06-06 | Geistlich Soehne Ag | Succinimides |
DE3479726D1 (de) * | 1983-05-18 | 1989-10-19 | Beecham Group Plc | Benzopyran derivatives. |
US5021432A (en) * | 1988-04-26 | 1991-06-04 | Yoshitomi Pharmaceutical Industries, Ltd. | Benzopyran compound and its pharmaceutical use |
GB9112721D0 (en) * | 1991-06-13 | 1991-07-31 | Smithkline Beecham Plc | Novel treatment |
US5624954A (en) * | 1991-06-13 | 1997-04-29 | Smithkline Beecham P.L.C. | Benzo- and pyridopyran derivatives having anxiolytic and anti-convulsant activity |
PT673374E (pt) * | 1992-12-11 | 2000-07-31 | Smithkline Beecham Plc | Composicao farmaceutica contendo compostos do tipo biciclico |
KR100326968B1 (ko) * | 1992-12-11 | 2002-07-27 | 스미스클라인비이참피이엘시이 | 약학적 활성을 가진 이환식 화합물 |
-
1995
- 1995-06-09 US US08/750,614 patent/US5843989A/en not_active Expired - Fee Related
- 1995-06-09 WO PCT/EP1995/002249 patent/WO1995034547A1/en active IP Right Grant
- 1995-06-09 JP JP8501606A patent/JPH10501256A/ja not_active Withdrawn
- 1995-06-09 EP EP95923297A patent/EP0764159B1/de not_active Expired - Lifetime
- 1995-06-09 DE DE69518322T patent/DE69518322T2/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO1995034547A1 (en) | 1995-12-21 |
EP0764159A1 (de) | 1997-03-26 |
DE69518322D1 (de) | 2000-09-14 |
EP0764159B1 (de) | 2000-08-09 |
JPH10501256A (ja) | 1998-02-03 |
US5843989A (en) | 1998-12-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |