NO326160B1 - N-(2-aryletyl)benzylaminer som antagonister av 5-HT6-reseptoren - Google Patents

N-(2-aryletyl)benzylaminer som antagonister av 5-HT6-reseptoren Download PDF

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NO326160B1
NO326160B1 NO20034289A NO20034289A NO326160B1 NO 326160 B1 NO326160 B1 NO 326160B1 NO 20034289 A NO20034289 A NO 20034289A NO 20034289 A NO20034289 A NO 20034289A NO 326160 B1 NO326160 B1 NO 326160B1
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group
alkyl
mmol
give
optionally substituted
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NO20034289A
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English (en)
Norwegian (no)
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NO20034289D0 (no
NO20034289L (no
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Jefferson Ray Mccowan
Matthew Joseph Fisher
John Mehnert Schaus
Zhaogen Chen
Michael Philip Cohen
Bruno Giethlen
James Ronald Gillig
Shawn Christopher Miller
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Lilly Co Eli
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Publication of NO20034289D0 publication Critical patent/NO20034289D0/no
Publication of NO20034289L publication Critical patent/NO20034289L/no
Publication of NO326160B1 publication Critical patent/NO326160B1/no

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    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
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    • C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
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    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
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    • C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C317/34—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring
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    • C07C323/32—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to an acyclic carbon atom of the carbon skeleton
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    • C07D209/04—Indoles; Hydrogenated indoles
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JP2004532209A (ja) 2004-10-21
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KR100894189B1 (ko) 2009-04-22
IL185871A0 (en) 2008-01-06
CN1610547A (zh) 2005-04-27
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DE60222396D1 (de) 2007-10-25
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PL364458A1 (en) 2004-12-13
SI1859798T1 (sl) 2016-07-29
US20090306110A1 (en) 2009-12-10
WO2002078693A2 (en) 2002-10-10
CZ20032614A3 (en) 2004-03-17
PL220721B1 (pl) 2015-12-31
KR20030090694A (ko) 2003-11-28
PT1859798E (pt) 2016-03-31
NO20034289D0 (no) 2003-09-25
IL157651A (en) 2010-02-17
DK1859798T3 (en) 2016-03-21
DZ3493A1 (fr) 2002-10-10
NO20034289L (no) 2003-11-28
US7157488B2 (en) 2007-01-02
ES2566056T3 (es) 2016-04-08
US20070099909A1 (en) 2007-05-03
US8044090B2 (en) 2011-10-25
SK12052003A3 (sk) 2004-09-08
ATE372768T1 (de) 2007-09-15
AU2002303094B2 (en) 2006-11-23
HRP20030771A2 (en) 2005-08-31
ZA200306795B (en) 2005-02-23
NZ527815A (en) 2005-05-27
CA2442114C (en) 2011-06-21
HUP0303651A2 (hu) 2004-03-01
DK1379239T3 (da) 2008-01-07
US20040132800A1 (en) 2004-07-08
EP1379239B1 (de) 2007-09-12
EA200301073A1 (ru) 2004-02-26
BR0208179A (pt) 2004-03-02
IL157651A0 (en) 2004-03-28
SK287463B6 (sk) 2010-10-07
MXPA03008726A (es) 2003-12-12
HUP0303651A3 (en) 2004-08-30

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