NO324046B1 - Anvendelse av et antistoff mot interleukin-6-reseptor. - Google Patents
Anvendelse av et antistoff mot interleukin-6-reseptor. Download PDFInfo
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- NO324046B1 NO324046B1 NO19971816A NO971816A NO324046B1 NO 324046 B1 NO324046 B1 NO 324046B1 NO 19971816 A NO19971816 A NO 19971816A NO 971816 A NO971816 A NO 971816A NO 324046 B1 NO324046 B1 NO 324046B1
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- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/01—Animal expressing industrially exogenous proteins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C—CHEMISTRY; METALLURGY
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP25701094 | 1994-10-21 | ||
| PCT/JP1995/002169 WO1996012503A1 (fr) | 1994-10-21 | 1995-10-20 | Remede contre des maladies provoquees par la production d'il-6 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO971816D0 NO971816D0 (no) | 1997-04-18 |
| NO971816L NO971816L (no) | 1997-06-18 |
| NO324046B1 true NO324046B1 (no) | 2007-08-06 |
Family
ID=17300476
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19971816A NO324046B1 (no) | 1994-10-21 | 1997-04-18 | Anvendelse av et antistoff mot interleukin-6-reseptor. |
| NO20073429A NO331944B1 (no) | 1994-10-21 | 2007-07-05 | Antistoff mot interleukin-6-reseptor for behandling av sykdom. |
| NO20073431A NO330588B1 (no) | 1994-10-21 | 2007-07-05 | Anvendelse av et antistoff mot IL-6-reseptor som blokkerer signal-transduksjonen til IL-6 for fremstilling av et farmasoytisk preparat for behandling av anemi. |
| NO20073432A NO330589B1 (no) | 1994-10-21 | 2007-07-05 | Anvendelse av et antistoff mot interleukin-6-reseptor som blokkerer IL-6 signal-transduksjon ved a inhibere bindingen av IL-6 til IL-6-reseptoren for fremstilling av et farmasoytisk preparat. |
| NO20073427A NO330615B1 (no) | 1994-10-21 | 2007-07-05 | Anvendelse av et antistoff mot IL-6-reseptor for fremstilling av et farmasoytisk preparat for behandling av kakeksi. |
| NO20073430A NO330582B1 (no) | 1994-10-21 | 2007-07-05 | Anvendelse av et antistoff mot interleukin-6-reseptor som blokkerer signal-transduksjonen til IL-6 for fremstilling av et farmasoytisk preparat for behandling av nefritt. |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20073429A NO331944B1 (no) | 1994-10-21 | 2007-07-05 | Antistoff mot interleukin-6-reseptor for behandling av sykdom. |
| NO20073431A NO330588B1 (no) | 1994-10-21 | 2007-07-05 | Anvendelse av et antistoff mot IL-6-reseptor som blokkerer signal-transduksjonen til IL-6 for fremstilling av et farmasoytisk preparat for behandling av anemi. |
| NO20073432A NO330589B1 (no) | 1994-10-21 | 2007-07-05 | Anvendelse av et antistoff mot interleukin-6-reseptor som blokkerer IL-6 signal-transduksjon ved a inhibere bindingen av IL-6 til IL-6-reseptoren for fremstilling av et farmasoytisk preparat. |
| NO20073427A NO330615B1 (no) | 1994-10-21 | 2007-07-05 | Anvendelse av et antistoff mot IL-6-reseptor for fremstilling av et farmasoytisk preparat for behandling av kakeksi. |
| NO20073430A NO330582B1 (no) | 1994-10-21 | 2007-07-05 | Anvendelse av et antistoff mot interleukin-6-reseptor som blokkerer signal-transduksjonen til IL-6 for fremstilling av et farmasoytisk preparat for behandling av nefritt. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20070036785A1 (fi) |
| EP (3) | EP2319535A3 (fi) |
| JP (1) | JP4896093B2 (fi) |
| CN (4) | CN1306963C (fi) |
| CA (1) | CA2203182C (fi) |
| CZ (3) | CZ296979B6 (fi) |
| FI (3) | FI121455B (fi) |
| HK (1) | HK1067062A1 (fi) |
| HU (2) | HU225392B1 (fi) |
| NO (6) | NO324046B1 (fi) |
| PL (1) | PL182089B1 (fi) |
| RU (1) | RU2147442C1 (fi) |
| WO (1) | WO1996012503A1 (fi) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8017121B2 (en) | 1994-06-30 | 2011-09-13 | Chugai Seiyaku Kabushika Kaisha | Chronic rheumatoid arthritis therapy containing IL-6 antagonist as effective component |
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| US5670373A (en) * | 1988-01-22 | 1997-09-23 | Kishimoto; Tadamitsu | Antibody to human interleukin-6 receptor |
| US5171840A (en) | 1988-01-22 | 1992-12-15 | Tadamitsu Kishimoto | Receptor protein for human B cell stimulatory factor-2 |
| US5814307A (en) * | 1989-04-10 | 1998-09-29 | Bristol-Myers Squibb Company | Method for regulating cell growth, leukocyte differentiation and tumor cell growth using Oncostatin M to stimulate synthesis of IL-6 |
| US5216128A (en) * | 1989-06-01 | 1993-06-01 | Yeda Research And Development Co., Ltd. | IFN-β2/IL-6 receptor its preparation and pharmaceutical compositions containing it |
| ATE144713T1 (de) * | 1989-07-20 | 1996-11-15 | Tadamitsu Kishimoto | Antikörper gegen menschlichen interleukin-6- rezeptor |
| JPH03155795A (ja) * | 1989-11-13 | 1991-07-03 | Chuzo Kishimoto | マウス・インターロイキン―６レセプター蛋白質 |
| JP3045172B2 (ja) * | 1990-05-19 | 2000-05-29 | 岸本 忠三 | Ｉｌ―６レセプターを利用したヒトｉｌ―６の化学的測定法及びそのためのキット |
| JP3212597B2 (ja) * | 1990-08-01 | 2001-09-25 | 忠三 岸本 | ヒトｉｌ―６レセプターの免疫化学的測定法及び測定用キット |
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| WO1994004659A1 (en) * | 1992-08-21 | 1994-03-03 | United States Of America, As Represented By The Secretary, Department Of Health & Human Services | A novel b-lymphoma cell line and antigen |
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| US5759546A (en) * | 1994-02-04 | 1998-06-02 | Weinberg; Andrew D. | Treatment of CD4 T-cell mediated conditions |
| ATE330629T1 (de) * | 1995-02-13 | 2006-07-15 | Chugai Pharmaceutical Co Ltd | Inhibitor des muskelproteinabbaus enthaltend einen il-6 rezeptor antikörper |
| US20020187150A1 (en) * | 1997-08-15 | 2002-12-12 | Chugai Seiyaku Kabushiki Kaisha | Preventive and/or therapeutic agent for systemic lupus erythematosus comprising anti-IL-6 receptor antibody as an active ingredient |
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| JP4889187B2 (ja) * | 2000-10-27 | 2012-03-07 | 中外製薬株式会社 | Ｉｌ−６アンタゴニストを有効成分として含有する血中ｍｍｐ−３濃度低下剤 |
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| GB2401040A (en) * | 2003-04-28 | 2004-11-03 | Chugai Pharmaceutical Co Ltd | Method for treating interleukin-6 related diseases |
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