NO300839B1 - Nye 2-cyano-3-hydroksy-propenamider og farmasöytiske preparater inneholdende slike - Google Patents

Nye 2-cyano-3-hydroksy-propenamider og farmasöytiske preparater inneholdende slike Download PDF

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Publication number
NO300839B1
NO300839B1 NO940020A NO940020A NO300839B1 NO 300839 B1 NO300839 B1 NO 300839B1 NO 940020 A NO940020 A NO 940020A NO 940020 A NO940020 A NO 940020A NO 300839 B1 NO300839 B1 NO 300839B1
Authority
NO
Norway
Prior art keywords
cyano
hydroxy
cyclopropyl
propenamide
formula
Prior art date
Application number
NO940020A
Other languages
English (en)
Norwegian (no)
Other versions
NO940020L (cs
NO940020D0 (no
Inventor
Elizabeth Anne Kuo
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of NO940020D0 publication Critical patent/NO940020D0/no
Publication of NO940020L publication Critical patent/NO940020L/no
Publication of NO300839B1 publication Critical patent/NO300839B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
NO940020A 1993-01-05 1994-01-04 Nye 2-cyano-3-hydroksy-propenamider og farmasöytiske preparater inneholdende slike NO300839B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939300083A GB9300083D0 (en) 1993-01-05 1993-01-05 Chemical compounds

Publications (3)

Publication Number Publication Date
NO940020D0 NO940020D0 (no) 1994-01-04
NO940020L NO940020L (cs) 1994-07-06
NO300839B1 true NO300839B1 (no) 1997-08-04

Family

ID=10728304

Family Applications (1)

Application Number Title Priority Date Filing Date
NO940020A NO300839B1 (no) 1993-01-05 1994-01-04 Nye 2-cyano-3-hydroksy-propenamider og farmasöytiske preparater inneholdende slike

Country Status (33)

Country Link
US (1) US5346912A (cs)
EP (1) EP0606175B1 (cs)
JP (1) JP3334988B2 (cs)
KR (1) KR100295717B1 (cs)
CN (1) CN1042935C (cs)
AT (1) ATE128968T1 (cs)
AU (1) AU663017B2 (cs)
BR (1) BR9400017A (cs)
CA (1) CA2112866C (cs)
CZ (1) CZ283948B6 (cs)
DE (1) DE69400024T2 (cs)
DK (1) DK0606175T3 (cs)
EE (1) EE03001B1 (cs)
ES (1) ES2078130T3 (cs)
FI (1) FI106553B (cs)
GB (1) GB9300083D0 (cs)
GR (1) GR3017723T3 (cs)
HR (1) HRP940006B1 (cs)
HU (1) HU216835B (cs)
IL (1) IL107788A (cs)
LT (1) LT3766B (cs)
LV (1) LV10712B (cs)
MX (1) MX9400274A (cs)
NO (1) NO300839B1 (cs)
NZ (1) NZ250520A (cs)
PL (1) PL175135B1 (cs)
RU (1) RU2126387C1 (cs)
SI (1) SI9300686A (cs)
SK (1) SK280508B6 (cs)
TW (1) TW259785B (cs)
UA (1) UA40573C2 (cs)
YU (1) YU49047B (cs)
ZA (1) ZA939118B (cs)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002521441A (ja) * 1998-07-28 2002-07-16 スミスクライン・ビーチャム・コーポレイション Ccr5モジュレーターとしてのプロペンアミド
WO2006115509A2 (en) 2004-06-24 2006-11-02 Novartis Vaccines And Diagnostics Inc. Small molecule immunopotentiators and assays for their detection
AU2008292238B2 (en) 2007-08-27 2014-06-12 Basf Se Pyrazole compounds for controlling invertebrate pests
KR101364869B1 (ko) 2008-09-24 2014-02-21 바스프 에스이 무척추 해충을 방제하기 위한 피라졸 화합물
WO2011003796A1 (en) 2009-07-06 2011-01-13 Basf Se Pyridazine compounds for controlling invertebrate pests
CN102471330A (zh) 2009-07-06 2012-05-23 巴斯夫欧洲公司 用于防治无脊椎动物害虫的哒嗪化合物
BR112012001597A2 (pt) 2009-07-24 2015-09-01 Basf Se Método para controlar e/ou combater pestes de invertebrados, método para a proteção do material de propagação de planta e/ou das plantas que crescem do mesmo, material de propagação de planta e método para tratar ou proteger um animal de infestação ou infecção por parasitas
KR20160079123A (ko) 2013-11-22 2016-07-05 젠자임 코포레이션 신경변성 질병을 치료하기 위한 신규한 방법
CN105693574B (zh) * 2014-11-25 2017-12-19 中国科学院大连化学物理研究所 2‑烷硫基烯酰胺衍生物及其合成方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL186239B (nl) 1975-06-05 Hoechst Ag Werkwijze voor de bereiding van een geneesmiddel met antiflogistische en/of analgetische werking, alsmede werkwijze voor de bereiding van een 2-hydroxyethylideencyaanazijnzuuranilide geschikt voor toepassing bij deze werkwijze.
DE2555789A1 (de) * 1975-12-11 1977-07-07 Hoechst Ag Neue cyanessigsaeureanilid-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel
ES8200663A1 (es) * 1980-06-23 1981-06-01 Made Labor Sa Un metodo para la produccion industrial de n-(4-piridilme- til)-benzamidas
US4435407A (en) * 1982-01-07 1984-03-06 Ciba-Geigy Corporation Certain substituted β-oxo-α-carbamoylpyrrolepropionitriles
DE3534440A1 (de) 1985-09-27 1987-04-02 Hoechst Ag Arzneimittel gegen chronische graft-versus-host-krankheiten sowie gegen autoimmunerkrankungen, insbesondere systemischen lupus erythematodes
US4888357A (en) 1988-01-26 1989-12-19 Bristol-Myers Company Antiarthritic β-cycloalkyl-β-oxopropionitriles
IL92508A0 (en) * 1988-12-08 1990-08-31 Ciba Geigy Ag Novel alpha-cyano-beta-oxopropionamides
BR9008022A (pt) * 1990-05-18 1993-04-06 Hoechst Ag Amida de acido isoxazol-4-carboxilico e amidas de acido hidroxialquilideno-cianoacetico,medicamentos contendo estes compostos e sua aplicacao
IL99811A (en) * 1990-10-30 1996-03-31 Roussel Uclaf 3-cycloalkyl-propanamides their tautomer forms and their salts preparation process and compositions containing them
IL102790A (en) * 1991-09-17 1996-01-31 Roussel Uclaf 3-Cycloalkyl-prop-2- enamide derivatives

Also Published As

Publication number Publication date
SK149593A3 (en) 1994-12-07
GR3017723T3 (en) 1996-01-31
LT3766B (en) 1996-03-25
DE69400024D1 (de) 1995-11-16
NO940020L (cs) 1994-07-06
FI940031A0 (fi) 1994-01-04
ES2078130T3 (es) 1995-12-01
PL175135B1 (pl) 1998-11-30
RU94000064A (ru) 1996-07-10
LTIP1634A (en) 1995-02-27
EE03001B1 (et) 1997-06-16
KR100295717B1 (ko) 2001-11-05
AU663017B2 (en) 1995-09-21
BR9400017A (pt) 1994-08-02
JP3334988B2 (ja) 2002-10-15
GB9300083D0 (en) 1993-03-03
CZ283948B6 (cs) 1998-07-15
DE69400024T2 (de) 1996-04-04
HRP940006B1 (en) 1999-12-31
LV10712A (lv) 1995-06-20
RU2126387C1 (ru) 1999-02-20
YU49047B (sh) 2003-07-07
NZ250520A (en) 1996-08-27
SI9300686A (en) 1994-09-30
US5346912A (en) 1994-09-13
ATE128968T1 (de) 1995-10-15
CN1097005A (zh) 1995-01-04
LV10712B (en) 1995-12-20
CA2112866C (fr) 2007-03-13
SK280508B6 (sk) 2000-03-13
KR940018363A (ko) 1994-08-16
AU5213093A (en) 1994-07-14
UA40573C2 (uk) 2001-08-15
DK0606175T3 (da) 1996-02-19
IL107788A0 (en) 1994-02-27
CA2112866A1 (fr) 1994-07-06
HU216835B (hu) 1999-09-28
NO940020D0 (no) 1994-01-04
HRP940006A2 (en) 1996-10-31
FI940031L (fi) 1994-07-06
HUT71471A (en) 1995-11-28
JPH06211793A (ja) 1994-08-02
MX9400274A (es) 1994-08-31
CN1042935C (zh) 1999-04-14
EP0606175A1 (fr) 1994-07-13
ZA939118B (en) 1995-01-18
TW259785B (en) 1995-10-11
IL107788A (en) 1998-08-16
EP0606175B1 (fr) 1995-10-11
PL301774A1 (en) 1994-07-11
YU82593A (sh) 1996-07-24
FI106553B (fi) 2001-02-28
HU9400033D0 (en) 1994-05-30
CZ292193A3 (en) 1994-07-13

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