ATE128968T1 - 2-cyano-2-hydroxypropenamidederivate, verfahren zu ihrer herstellung ihre verwendung als arzneimittel und diese enthaltende pharmazeutische zusammensetzungen. - Google Patents

2-cyano-2-hydroxypropenamidederivate, verfahren zu ihrer herstellung ihre verwendung als arzneimittel und diese enthaltende pharmazeutische zusammensetzungen.

Info

Publication number
ATE128968T1
ATE128968T1 AT94400009T AT94400009T ATE128968T1 AT E128968 T1 ATE128968 T1 AT E128968T1 AT 94400009 T AT94400009 T AT 94400009T AT 94400009 T AT94400009 T AT 94400009T AT E128968 T1 ATE128968 T1 AT E128968T1
Authority
AT
Austria
Prior art keywords
hydroxypropenamide
cyano
derivatives
production
pharmaceutical compositions
Prior art date
Application number
AT94400009T
Other languages
English (en)
Inventor
Elizabeth Anne Kuo
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Application granted granted Critical
Publication of ATE128968T1 publication Critical patent/ATE128968T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
AT94400009T 1993-01-05 1994-01-04 2-cyano-2-hydroxypropenamidederivate, verfahren zu ihrer herstellung ihre verwendung als arzneimittel und diese enthaltende pharmazeutische zusammensetzungen. ATE128968T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939300083A GB9300083D0 (en) 1993-01-05 1993-01-05 Chemical compounds

Publications (1)

Publication Number Publication Date
ATE128968T1 true ATE128968T1 (de) 1995-10-15

Family

ID=10728304

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94400009T ATE128968T1 (de) 1993-01-05 1994-01-04 2-cyano-2-hydroxypropenamidederivate, verfahren zu ihrer herstellung ihre verwendung als arzneimittel und diese enthaltende pharmazeutische zusammensetzungen.

Country Status (33)

Country Link
US (1) US5346912A (de)
EP (1) EP0606175B1 (de)
JP (1) JP3334988B2 (de)
KR (1) KR100295717B1 (de)
CN (1) CN1042935C (de)
AT (1) ATE128968T1 (de)
AU (1) AU663017B2 (de)
BR (1) BR9400017A (de)
CA (1) CA2112866C (de)
CZ (1) CZ283948B6 (de)
DE (1) DE69400024T2 (de)
DK (1) DK0606175T3 (de)
EE (1) EE03001B1 (de)
ES (1) ES2078130T3 (de)
FI (1) FI106553B (de)
GB (1) GB9300083D0 (de)
GR (1) GR3017723T3 (de)
HR (1) HRP940006B1 (de)
HU (1) HU216835B (de)
IL (1) IL107788A (de)
LT (1) LT3766B (de)
LV (1) LV10712B (de)
MX (1) MX9400274A (de)
NO (1) NO300839B1 (de)
NZ (1) NZ250520A (de)
PL (1) PL175135B1 (de)
RU (1) RU2126387C1 (de)
SI (1) SI9300686A (de)
SK (1) SK280508B6 (de)
TW (1) TW259785B (de)
UA (1) UA40573C2 (de)
YU (1) YU49047B (de)
ZA (1) ZA939118B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1100495A4 (de) * 1998-07-28 2002-09-25 Smithkline Beecham Corp Propenamide als ccr5 modulatoren
EP1768662A2 (de) 2004-06-24 2007-04-04 Novartis Vaccines and Diagnostics, Inc. Immunstimulatoren kleiner moleküle und assays für deren nachweis
TW200917962A (en) 2007-08-27 2009-05-01 Basf Se Pyrazole compounds for controlling invertebrate pests
US8729083B2 (en) 2008-09-24 2014-05-20 Basf Se Pyrazole compounds for controlling invertebrate pests
JP2012532176A (ja) 2009-07-06 2012-12-13 ビーエーエスエフ ソシエタス・ヨーロピア 無脊椎動物系害虫防除用ピリダジン化合物
BR112012000149B8 (pt) 2009-07-06 2021-01-12 Basf Se compostos de piridazina, método para controlar pragas invertebradas e método para proteger material de propagação de planta e/ou as plantas
US9125414B2 (en) 2009-07-24 2015-09-08 Basf Se Pyridine derivatives compounds for controlling invertebrate pests
KR20160079123A (ko) 2013-11-22 2016-07-05 젠자임 코포레이션 신경변성 질병을 치료하기 위한 신규한 방법
CN105693574B (zh) * 2014-11-25 2017-12-19 中国科学院大连化学物理研究所 2‑烷硫基烯酰胺衍生物及其合成方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL186239B (nl) 1975-06-05 Hoechst Ag Werkwijze voor de bereiding van een geneesmiddel met antiflogistische en/of analgetische werking, alsmede werkwijze voor de bereiding van een 2-hydroxyethylideencyaanazijnzuuranilide geschikt voor toepassing bij deze werkwijze.
DE2555789A1 (de) * 1975-12-11 1977-07-07 Hoechst Ag Neue cyanessigsaeureanilid-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel
US4435407A (en) * 1982-01-07 1984-03-06 Ciba-Geigy Corporation Certain substituted β-oxo-α-carbamoylpyrrolepropionitriles
DE3534440A1 (de) 1985-09-27 1987-04-02 Hoechst Ag Arzneimittel gegen chronische graft-versus-host-krankheiten sowie gegen autoimmunerkrankungen, insbesondere systemischen lupus erythematodes
US4888357A (en) 1988-01-26 1989-12-19 Bristol-Myers Company Antiarthritic β-cycloalkyl-β-oxopropionitriles
IL92508A0 (en) * 1988-12-08 1990-08-31 Ciba Geigy Ag Novel alpha-cyano-beta-oxopropionamides
KR100188801B1 (ko) * 1990-05-18 1999-06-01 엥겔하르트 라피체 이속사졸-4카복스아미드 및 하이드록시알킬리덴 시아노아세트아미드 및 이들 화합물을 함유하는 약제학적 조성물
IL99811A (en) * 1990-10-30 1996-03-31 Roussel Uclaf 3-Cycloalkyl-propanamides, tautomeric forms of these, their salts, method of preparation, use as drugs and preparations containing them
IL102790A (en) * 1991-09-17 1996-01-31 Roussel Uclaf History of 3-cycloalkyl-prop-2-anamide

Also Published As

Publication number Publication date
SK280508B6 (sk) 2000-03-13
NO940020D0 (no) 1994-01-04
CA2112866A1 (fr) 1994-07-06
FI940031A (fi) 1994-07-06
IL107788A (en) 1998-08-16
PL175135B1 (pl) 1998-11-30
EE03001B1 (et) 1997-06-16
EP0606175B1 (de) 1995-10-11
LT3766B (en) 1996-03-25
CN1042935C (zh) 1999-04-14
BR9400017A (pt) 1994-08-02
TW259785B (en) 1995-10-11
DE69400024T2 (de) 1996-04-04
CN1097005A (zh) 1995-01-04
HRP940006B1 (en) 1999-12-31
HUT71471A (en) 1995-11-28
MX9400274A (es) 1994-08-31
NZ250520A (en) 1996-08-27
NO300839B1 (no) 1997-08-04
NO940020L (de) 1994-07-06
AU5213093A (en) 1994-07-14
DE69400024D1 (de) 1995-11-16
LV10712A (lv) 1995-06-20
LTIP1634A (en) 1995-02-27
YU49047B (sh) 2003-07-07
YU82593A (sh) 1996-07-24
DK0606175T3 (da) 1996-02-19
LV10712B (en) 1995-12-20
RU2126387C1 (ru) 1999-02-20
HRP940006A2 (en) 1996-10-31
UA40573C2 (uk) 2001-08-15
SI9300686A (en) 1994-09-30
CA2112866C (fr) 2007-03-13
AU663017B2 (en) 1995-09-21
FI940031A0 (fi) 1994-01-04
JPH06211793A (ja) 1994-08-02
KR940018363A (ko) 1994-08-16
JP3334988B2 (ja) 2002-10-15
IL107788A0 (en) 1994-02-27
ZA939118B (en) 1995-01-18
PL301774A1 (en) 1994-07-11
ES2078130T3 (es) 1995-12-01
KR100295717B1 (ko) 2001-11-05
HU216835B (hu) 1999-09-28
CZ283948B6 (cs) 1998-07-15
CZ292193A3 (en) 1994-07-13
FI106553B (fi) 2001-02-28
GR3017723T3 (en) 1996-01-31
SK149593A3 (en) 1994-12-07
GB9300083D0 (en) 1993-03-03
EP0606175A1 (de) 1994-07-13
US5346912A (en) 1994-09-13
RU94000064A (ru) 1996-07-10
HU9400033D0 (en) 1994-05-30

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