HRP940006B1 - 2-cyano-3-hydroxypropenamide derivatives, process for their preparation, their use as medicaments and pharmaceutical compositions containing them - Google Patents
2-cyano-3-hydroxypropenamide derivatives, process for their preparation, their use as medicaments and pharmaceutical compositions containing themInfo
- Publication number
- HRP940006B1 HRP940006B1 HR9300083.4A HRP940006A HRP940006B1 HR P940006 B1 HRP940006 B1 HR P940006B1 HR P940006 A HRP940006 A HR P940006A HR P940006 B1 HRP940006 B1 HR P940006B1
- Authority
- HR
- Croatia
- Prior art keywords
- hydroxypropenamide
- medicaments
- cyano
- derivatives
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939300083A GB9300083D0 (en) | 1993-01-05 | 1993-01-05 | Chemical compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HRP940006A2 HRP940006A2 (en) | 1996-10-31 |
| HRP940006B1 true HRP940006B1 (en) | 1999-12-31 |
Family
ID=10728304
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR9300083.4A HRP940006B1 (en) | 1993-01-05 | 1994-01-04 | 2-cyano-3-hydroxypropenamide derivatives, process for their preparation, their use as medicaments and pharmaceutical compositions containing them |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US5346912A (de) |
| EP (1) | EP0606175B1 (de) |
| JP (1) | JP3334988B2 (de) |
| KR (1) | KR100295717B1 (de) |
| CN (1) | CN1042935C (de) |
| AT (1) | ATE128968T1 (de) |
| AU (1) | AU663017B2 (de) |
| BR (1) | BR9400017A (de) |
| CA (1) | CA2112866C (de) |
| CZ (1) | CZ283948B6 (de) |
| DE (1) | DE69400024T2 (de) |
| DK (1) | DK0606175T3 (de) |
| EE (1) | EE03001B1 (de) |
| ES (1) | ES2078130T3 (de) |
| FI (1) | FI106553B (de) |
| GB (1) | GB9300083D0 (de) |
| GR (1) | GR3017723T3 (de) |
| HR (1) | HRP940006B1 (de) |
| HU (1) | HU216835B (de) |
| IL (1) | IL107788A (de) |
| LT (1) | LT3766B (de) |
| LV (1) | LV10712B (de) |
| MX (1) | MX9400274A (de) |
| NO (1) | NO300839B1 (de) |
| NZ (1) | NZ250520A (de) |
| PL (1) | PL175135B1 (de) |
| RU (1) | RU2126387C1 (de) |
| SI (1) | SI9300686A (de) |
| SK (1) | SK280508B6 (de) |
| TW (1) | TW259785B (de) |
| UA (1) | UA40573C2 (de) |
| YU (1) | YU49047B (de) |
| ZA (1) | ZA939118B (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000006153A1 (en) * | 1998-07-28 | 2000-02-10 | Smithkline Beecham Corporation | Propenamides as ccr5 modulators |
| CA2571710A1 (en) | 2004-06-24 | 2006-11-02 | Nicholas Valiante | Small molecule immunopotentiators and assays for their detection |
| US8642597B2 (en) | 2007-08-27 | 2014-02-04 | Basf Se | Pyrazole compounds for controlling invertebrate pests |
| BRPI0919061B1 (pt) | 2008-09-24 | 2017-07-18 | Basf Se | Pyrazole compounds, method for controlling invertebrate pests, method of protecting plant and / or plant propagation material, agricultural composition and use of a compound |
| JP2012532175A (ja) | 2009-07-06 | 2012-12-13 | ビーエーエスエフ ソシエタス・ヨーロピア | 無脊椎動物系害虫防除用ピリダジン化合物 |
| ES2472918T3 (es) | 2009-07-06 | 2014-07-03 | Basf Se | Compuestos de piridazina para controlar plagas de invertebrados |
| EP2456308A2 (de) | 2009-07-24 | 2012-05-30 | Basf Se | Pyridinderivate zur bekämpfung von wirbellosen schädlingen |
| EA201691057A1 (ru) | 2013-11-22 | 2016-10-31 | Джензим Корпорейшн | Новые способы лечения нейродегенеративных заболеваний |
| CN105693574B (zh) * | 2014-11-25 | 2017-12-19 | 中国科学院大连化学物理研究所 | 2‑烷硫基烯酰胺衍生物及其合成方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL186239B (nl) | 1975-06-05 | Hoechst Ag | Werkwijze voor de bereiding van een geneesmiddel met antiflogistische en/of analgetische werking, alsmede werkwijze voor de bereiding van een 2-hydroxyethylideencyaanazijnzuuranilide geschikt voor toepassing bij deze werkwijze. | |
| DE2555789A1 (de) * | 1975-12-11 | 1977-07-07 | Hoechst Ag | Neue cyanessigsaeureanilid-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel |
| US4435407A (en) * | 1982-01-07 | 1984-03-06 | Ciba-Geigy Corporation | Certain substituted β-oxo-α-carbamoylpyrrolepropionitriles |
| DE3534440A1 (de) | 1985-09-27 | 1987-04-02 | Hoechst Ag | Arzneimittel gegen chronische graft-versus-host-krankheiten sowie gegen autoimmunerkrankungen, insbesondere systemischen lupus erythematodes |
| US4888357A (en) | 1988-01-26 | 1989-12-19 | Bristol-Myers Company | Antiarthritic β-cycloalkyl-β-oxopropionitriles |
| IL92508A0 (en) * | 1988-12-08 | 1990-08-31 | Ciba Geigy Ag | Novel alpha-cyano-beta-oxopropionamides |
| DE59010701D1 (de) * | 1990-05-18 | 1997-05-22 | Hoechst Ag | Isoxazol-4-carbonsäureamide und hydroxyalkyliden-cyanessigsäureamide, diese verbindungen enthaltende arzneimittel und deren verwendung |
| IL99811A (en) * | 1990-10-30 | 1996-03-31 | Roussel Uclaf | 3-Cycloalkyl-propanamides, tautomeric forms of these, their salts, method of preparation, use as drugs and preparations containing them |
| IL102790A (en) * | 1991-09-17 | 1996-01-31 | Roussel Uclaf | History of 3-cycloalkyl-prop-2-anamide |
-
1993
- 1993-01-05 GB GB939300083A patent/GB9300083D0/en active Pending
- 1993-11-29 IL IL10778893A patent/IL107788A/en not_active IP Right Cessation
- 1993-12-03 AU AU52130/93A patent/AU663017B2/en not_active Expired
- 1993-12-06 ZA ZA939118A patent/ZA939118B/xx unknown
- 1993-12-20 NZ NZ250520A patent/NZ250520A/en not_active IP Right Cessation
- 1993-12-20 LT LTIP1634A patent/LT3766B/lt not_active IP Right Cessation
- 1993-12-20 US US08/170,372 patent/US5346912A/en not_active Expired - Lifetime
- 1993-12-24 SI SI9300686A patent/SI9300686A/sl unknown
- 1993-12-28 JP JP34951193A patent/JP3334988B2/ja not_active Expired - Lifetime
- 1993-12-29 YU YU82593A patent/YU49047B/sh unknown
- 1993-12-29 SK SK1495-93A patent/SK280508B6/sk not_active IP Right Cessation
- 1993-12-30 CZ CZ932921A patent/CZ283948B6/cs not_active IP Right Cessation
-
1994
- 1994-01-03 PL PL94301774A patent/PL175135B1/pl unknown
- 1994-01-04 LV LVP-94-02A patent/LV10712B/en unknown
- 1994-01-04 KR KR1019940000057A patent/KR100295717B1/ko not_active IP Right Cessation
- 1994-01-04 FI FI940031A patent/FI106553B/fi not_active IP Right Cessation
- 1994-01-04 CN CN94100187A patent/CN1042935C/zh not_active Expired - Lifetime
- 1994-01-04 EP EP94400009A patent/EP0606175B1/de not_active Expired - Lifetime
- 1994-01-04 BR BR9400017A patent/BR9400017A/pt not_active Application Discontinuation
- 1994-01-04 HR HR9300083.4A patent/HRP940006B1/xx not_active IP Right Cessation
- 1994-01-04 RU RU94000064A patent/RU2126387C1/ru active
- 1994-01-04 DE DE69400024T patent/DE69400024T2/de not_active Expired - Lifetime
- 1994-01-04 AT AT94400009T patent/ATE128968T1/de active
- 1994-01-04 DK DK94400009.0T patent/DK0606175T3/da active
- 1994-01-04 NO NO940020A patent/NO300839B1/no not_active IP Right Cessation
- 1994-01-04 ES ES94400009T patent/ES2078130T3/es not_active Expired - Lifetime
- 1994-01-04 UA UA94005036A patent/UA40573C2/uk unknown
- 1994-01-05 MX MX9400274A patent/MX9400274A/es unknown
- 1994-01-05 CA CA002112866A patent/CA2112866C/fr not_active Expired - Lifetime
- 1994-01-05 HU HU9400033A patent/HU216835B/hu unknown
- 1994-01-31 TW TW083100783A patent/TW259785B/zh not_active IP Right Cessation
- 1994-11-14 EE EE9400360A patent/EE03001B1/xx unknown
-
1995
- 1995-10-12 GR GR950401071T patent/GR3017723T3/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A1OB | Publication of a patent application | ||
| AIPI | Request for the grant of a patent on the basis of a substantive examination of a patent application | ||
| B1PR | Patent granted | ||
| PNAN | Change of the applicant name, address/residence |
Owner name: HOECHST MARION ROUSSEL, FR Owner name: ROUSSEL UCLAF, FR Owner name: AVENTIS PHARMA S.A., FR |
|
| ODRP | Renewal fee for the maintenance of a patent |
Payment date: 20121205 Year of fee payment: 20 |
|
| PB20 | Patent expired after termination of 20 years |
Effective date: 20140105 |