DK0606175T3 - 2-cyan-3-hydroxypropenamider, fremgangsmåde til deres fremstilling, deres anvendelse som lægemidler samt farmaceutiske præparater med indhold deraf - Google Patents

2-cyan-3-hydroxypropenamider, fremgangsmåde til deres fremstilling, deres anvendelse som lægemidler samt farmaceutiske præparater med indhold deraf

Info

Publication number
DK0606175T3
DK0606175T3 DK94400009.0T DK94400009T DK0606175T3 DK 0606175 T3 DK0606175 T3 DK 0606175T3 DK 94400009 T DK94400009 T DK 94400009T DK 0606175 T3 DK0606175 T3 DK 0606175T3
Authority
DK
Denmark
Prior art keywords
hydroxypropenamides
cyan
pharmaceuticals
preparation
pharmaceutical compositions
Prior art date
Application number
DK94400009.0T
Other languages
Danish (da)
English (en)
Inventor
Elizabeth Anne Kuo
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Application granted granted Critical
Publication of DK0606175T3 publication Critical patent/DK0606175T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DK94400009.0T 1993-01-05 1994-01-04 2-cyan-3-hydroxypropenamider, fremgangsmåde til deres fremstilling, deres anvendelse som lægemidler samt farmaceutiske præparater med indhold deraf DK0606175T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939300083A GB9300083D0 (en) 1993-01-05 1993-01-05 Chemical compounds

Publications (1)

Publication Number Publication Date
DK0606175T3 true DK0606175T3 (da) 1996-02-19

Family

ID=10728304

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94400009.0T DK0606175T3 (da) 1993-01-05 1994-01-04 2-cyan-3-hydroxypropenamider, fremgangsmåde til deres fremstilling, deres anvendelse som lægemidler samt farmaceutiske præparater med indhold deraf

Country Status (33)

Country Link
US (1) US5346912A (de)
EP (1) EP0606175B1 (de)
JP (1) JP3334988B2 (de)
KR (1) KR100295717B1 (de)
CN (1) CN1042935C (de)
AT (1) ATE128968T1 (de)
AU (1) AU663017B2 (de)
BR (1) BR9400017A (de)
CA (1) CA2112866C (de)
CZ (1) CZ283948B6 (de)
DE (1) DE69400024T2 (de)
DK (1) DK0606175T3 (de)
EE (1) EE03001B1 (de)
ES (1) ES2078130T3 (de)
FI (1) FI106553B (de)
GB (1) GB9300083D0 (de)
GR (1) GR3017723T3 (de)
HR (1) HRP940006B1 (de)
HU (1) HU216835B (de)
IL (1) IL107788A (de)
LT (1) LT3766B (de)
LV (1) LV10712B (de)
MX (1) MX9400274A (de)
NO (1) NO300839B1 (de)
NZ (1) NZ250520A (de)
PL (1) PL175135B1 (de)
RU (1) RU2126387C1 (de)
SI (1) SI9300686A (de)
SK (1) SK280508B6 (de)
TW (1) TW259785B (de)
UA (1) UA40573C2 (de)
YU (1) YU49047B (de)
ZA (1) ZA939118B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000006153A1 (en) * 1998-07-28 2000-02-10 Smithkline Beecham Corporation Propenamides as ccr5 modulators
CA2571710A1 (en) 2004-06-24 2006-11-02 Nicholas Valiante Small molecule immunopotentiators and assays for their detection
US8642597B2 (en) 2007-08-27 2014-02-04 Basf Se Pyrazole compounds for controlling invertebrate pests
BRPI0919061B1 (pt) 2008-09-24 2017-07-18 Basf Se Pyrazole compounds, method for controlling invertebrate pests, method of protecting plant and / or plant propagation material, agricultural composition and use of a compound
JP2012532175A (ja) 2009-07-06 2012-12-13 ビーエーエスエフ ソシエタス・ヨーロピア 無脊椎動物系害虫防除用ピリダジン化合物
ES2472918T3 (es) 2009-07-06 2014-07-03 Basf Se Compuestos de piridazina para controlar plagas de invertebrados
EP2456308A2 (de) 2009-07-24 2012-05-30 Basf Se Pyridinderivate zur bekämpfung von wirbellosen schädlingen
EA201691057A1 (ru) 2013-11-22 2016-10-31 Джензим Корпорейшн Новые способы лечения нейродегенеративных заболеваний
CN105693574B (zh) * 2014-11-25 2017-12-19 中国科学院大连化学物理研究所 2‑烷硫基烯酰胺衍生物及其合成方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL186239B (nl) 1975-06-05 Hoechst Ag Werkwijze voor de bereiding van een geneesmiddel met antiflogistische en/of analgetische werking, alsmede werkwijze voor de bereiding van een 2-hydroxyethylideencyaanazijnzuuranilide geschikt voor toepassing bij deze werkwijze.
DE2555789A1 (de) * 1975-12-11 1977-07-07 Hoechst Ag Neue cyanessigsaeureanilid-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel
US4435407A (en) * 1982-01-07 1984-03-06 Ciba-Geigy Corporation Certain substituted β-oxo-α-carbamoylpyrrolepropionitriles
DE3534440A1 (de) 1985-09-27 1987-04-02 Hoechst Ag Arzneimittel gegen chronische graft-versus-host-krankheiten sowie gegen autoimmunerkrankungen, insbesondere systemischen lupus erythematodes
US4888357A (en) 1988-01-26 1989-12-19 Bristol-Myers Company Antiarthritic β-cycloalkyl-β-oxopropionitriles
IL92508A0 (en) * 1988-12-08 1990-08-31 Ciba Geigy Ag Novel alpha-cyano-beta-oxopropionamides
DE59010701D1 (de) * 1990-05-18 1997-05-22 Hoechst Ag Isoxazol-4-carbonsäureamide und hydroxyalkyliden-cyanessigsäureamide, diese verbindungen enthaltende arzneimittel und deren verwendung
IL99811A (en) * 1990-10-30 1996-03-31 Roussel Uclaf 3-Cycloalkyl-propanamides, tautomeric forms of these, their salts, method of preparation, use as drugs and preparations containing them
IL102790A (en) * 1991-09-17 1996-01-31 Roussel Uclaf History of 3-cycloalkyl-prop-2-anamide

Also Published As

Publication number Publication date
FI940031A (fi) 1994-07-06
EP0606175A1 (de) 1994-07-13
KR940018363A (ko) 1994-08-16
YU49047B (sh) 2003-07-07
FI106553B (fi) 2001-02-28
NZ250520A (en) 1996-08-27
CZ283948B6 (cs) 1998-07-15
IL107788A0 (en) 1994-02-27
KR100295717B1 (ko) 2001-11-05
HRP940006B1 (en) 1999-12-31
LTIP1634A (en) 1995-02-27
CN1042935C (zh) 1999-04-14
LV10712A (lv) 1995-06-20
NO300839B1 (no) 1997-08-04
NO940020D0 (no) 1994-01-04
ZA939118B (en) 1995-01-18
UA40573C2 (uk) 2001-08-15
CN1097005A (zh) 1995-01-04
US5346912A (en) 1994-09-13
ATE128968T1 (de) 1995-10-15
CA2112866A1 (fr) 1994-07-06
HRP940006A2 (en) 1996-10-31
HU216835B (hu) 1999-09-28
FI940031A0 (fi) 1994-01-04
CZ292193A3 (en) 1994-07-13
JP3334988B2 (ja) 2002-10-15
JPH06211793A (ja) 1994-08-02
AU663017B2 (en) 1995-09-21
HUT71471A (en) 1995-11-28
SK149593A3 (en) 1994-12-07
ES2078130T3 (es) 1995-12-01
TW259785B (en) 1995-10-11
DE69400024T2 (de) 1996-04-04
RU94000064A (ru) 1996-07-10
HU9400033D0 (en) 1994-05-30
RU2126387C1 (ru) 1999-02-20
IL107788A (en) 1998-08-16
EE03001B1 (et) 1997-06-16
CA2112866C (fr) 2007-03-13
BR9400017A (pt) 1994-08-02
DE69400024D1 (de) 1995-11-16
GB9300083D0 (en) 1993-03-03
NO940020L (de) 1994-07-06
LT3766B (en) 1996-03-25
GR3017723T3 (en) 1996-01-31
SI9300686A (en) 1994-09-30
PL175135B1 (pl) 1998-11-30
AU5213093A (en) 1994-07-14
PL301774A1 (en) 1994-07-11
MX9400274A (es) 1994-08-31
LV10712B (en) 1995-12-20
SK280508B6 (sk) 2000-03-13
EP0606175B1 (de) 1995-10-11
YU82593A (sh) 1996-07-24

Similar Documents

Publication Publication Date Title
DK0778277T3 (da) Substituerede heterocycliske derivater som CRF antagonister
DE69018908D1 (de) N-aryl und N-Heteroarylamide und Harnstoffderivate als Inhibitoren von Acyl-Coenzym A: Cholesterol-Acyl-Transferase.
ES2176204T3 (es) Antidepresivos que contienen un derivado de xantina.
MX9202142A (es) Nuevos derivados de urea, proceso para su preparacion, y composicion farmaceutica que los comprende.
DK0551230T3 (da) 2-cyan-3-hydroxyenamider, fremgangsmåde til deres fremstilling, deres anvendelse som lægemidler samt farmaceutiske præparater med indhold deraf
DK0519327T3 (da) N-Acyl-S-(2-hydroxyalkyl) -cysteiner, deres fremstilling samt deres anvendelse som mellemprodukter til fremstilling af synt
ATE207906T1 (de) Phenylimidazolidine und deren verwendung als anti-androgene mittel
DK0606175T3 (da) 2-cyan-3-hydroxypropenamider, fremgangsmåde til deres fremstilling, deres anvendelse som lægemidler samt farmaceutiske præparater med indhold deraf
DK50086D0 (da) 3-phenyl-tetrahydropyridinderivater
DK0404359T3 (da) Dibenzothiazepin-derivater, der er nyttige som antispasmodiske midler
ATE260252T1 (de) Thiocolchicin-derivate mit entzündungshemmender und muskelrelaxierender wirkung
ES2111871T3 (es) Nuevos derivados de aminoacidos, su procedimiento de preparacion y composiciones farmaceuticas que los contienen.
FI962587A (fi) 1,3-oksatsin-4-onijohdannaiset, menetelmä ja välituotteet niiden valmistamiseksi ja niiden käyttö herbisideinä
BR9400015A (pt) Processo para preparação de compostos e compostos
ATE273979T1 (de) Xanthinderivate, zwischenprodukte und verwendung zur behandlung von osteoporosis
NO180779B (no) Pyridinderivater, fremgangsmåte for deres fremstilling, anvendelse derav, sett omfattende slike, og utgangsforbindelse for fremgangsmåten
ES2143159T3 (es) Nuevos derivados de 2-ciano-3-hidroxi-propenamidas que comprenden un radical trifluorometilsulfonilfenilo/trifluorometilsulfinilfenilo, procedimiento de preparacion, aplicacion como medicamentos y composiciones farmaceuticas que los contienen.
DK0418990T3 (da) 13-brom- og 13,14-dibrom-ergoliner, deres fremstilling og anvendelse i lægemidler
PT90815A (pt) Processo de preparacao de derivados da fenotiazina