DK0418990T3 - 13-brom- og 13,14-dibrom-ergoliner, deres fremstilling og anvendelse i lægemidler - Google Patents
13-brom- og 13,14-dibrom-ergoliner, deres fremstilling og anvendelse i lægemidlerInfo
- Publication number
- DK0418990T3 DK0418990T3 DK90250235.0T DK90250235T DK0418990T3 DK 0418990 T3 DK0418990 T3 DK 0418990T3 DK 90250235 T DK90250235 T DK 90250235T DK 0418990 T3 DK0418990 T3 DK 0418990T3
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- ergolines
- dibromo
- pharmaceuticals
- bromo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
- C07D457/06—Lysergic acid amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
- C07D457/12—Nitrogen atoms
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3931819A DE3931819A1 (de) | 1989-09-20 | 1989-09-20 | 13-brom und 13, 14-dibrom-ergoline, ihre herstellung und verwendung in arzneimitteln |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0418990T3 true DK0418990T3 (da) | 1994-03-14 |
Family
ID=6390055
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK90250235.0T DK0418990T3 (da) | 1989-09-20 | 1990-09-13 | 13-brom- og 13,14-dibrom-ergoliner, deres fremstilling og anvendelse i lægemidler |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0418990B1 (da) |
| JP (1) | JPH03120277A (da) |
| AT (1) | ATE97130T1 (da) |
| CA (1) | CA2025744A1 (da) |
| CZ (1) | CZ278319B6 (da) |
| DD (1) | DD295848A5 (da) |
| DE (2) | DE3931819A1 (da) |
| DK (1) | DK0418990T3 (da) |
| ES (1) | ES2062313T3 (da) |
| HU (1) | HU206346B (da) |
| IE (1) | IE65416B1 (da) |
| PT (1) | PT95350A (da) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4123587A1 (de) * | 1991-07-12 | 1993-01-14 | Schering Ag | 2,14-disubstituierte ergoline, deren herstellung und verwendung in arzneimitteln |
| US9657020B2 (en) | 2015-01-20 | 2017-05-23 | Xoc Pharmaceuticals, Inc. | Ergoline compounds and uses thereof |
| BR112017015510A2 (pt) | 2015-01-20 | 2018-01-30 | Xoc Pharmaceuticals Inc | composto de fórmula estrutural (i), método de tratamento e/ou prevenção, método de agonização do receptor d2 em um indivíduo, método de antagonização do receptor d3 em um indivíduo, método de agonização do receptor 5-ht1d em um indivíduo, método de agonização do receptor 5-ht1a em um indivíduo, método de agonização seletiva do receptor 5-ht1d em vez do receptor 5-ht1b em um indivíduo, método de agonização seletiva do re-ceptor 5-ht2c em vez do receptor 5-ht2a ou 5-ht2b em um indivíduo, método de agonização do receptor 5-ht2c em um indivíduo, método de fornecimento de atividade antagonista funcional no receptor 5-ht2b ou receptor 5-ht7, e, método de fornecimento de atividade antagonista funcional nos receptores adrenérgicos em um indivíduo |
| WO2018223065A1 (en) | 2017-06-01 | 2018-12-06 | Xoc Pharmaceuticals, Inc. | Ergoline derivatives for use in medicine |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1413068A (en) * | 1972-06-22 | 1975-11-05 | Farmaceutici Italia | Bromoergolines |
| DE2802023A1 (de) * | 1977-01-28 | 1978-08-03 | Sandoz Ag | Neue ergotderivate, ihre herstellung und verwendung |
| GB2074566B (en) * | 1980-04-03 | 1983-11-02 | Erba Farmitalia | Ergoline derivatives |
| DE3533675A1 (de) * | 1985-09-19 | 1987-03-26 | Schering Ag | Neue 12- und 13-brom-ergolinderivate |
| DE3730124A1 (de) * | 1987-09-08 | 1989-03-16 | Eich Eckart | Neue festuclavin- und pyroclavin-derivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel |
-
1989
- 1989-09-20 DE DE3931819A patent/DE3931819A1/de not_active Withdrawn
-
1990
- 1990-09-13 ES ES90250235T patent/ES2062313T3/es not_active Expired - Lifetime
- 1990-09-13 DE DE90250235T patent/DE59003446D1/de not_active Expired - Lifetime
- 1990-09-13 AT AT90250235T patent/ATE97130T1/de not_active IP Right Cessation
- 1990-09-13 DK DK90250235.0T patent/DK0418990T3/da active
- 1990-09-13 EP EP90250235A patent/EP0418990B1/de not_active Expired - Lifetime
- 1990-09-18 IE IE336990A patent/IE65416B1/en not_active IP Right Cessation
- 1990-09-19 CA CA002025744A patent/CA2025744A1/en not_active Abandoned
- 1990-09-19 DD DD90344101A patent/DD295848A5/de not_active IP Right Cessation
- 1990-09-19 PT PT95350A patent/PT95350A/pt not_active Application Discontinuation
- 1990-09-19 HU HU905969A patent/HU206346B/hu not_active IP Right Cessation
- 1990-09-20 CZ CS904582A patent/CZ278319B6/cs unknown
- 1990-09-20 JP JP2249012A patent/JPH03120277A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2025744A1 (en) | 1991-03-21 |
| DE3931819A1 (de) | 1991-03-28 |
| EP0418990A3 (en) | 1991-07-03 |
| IE65416B1 (en) | 1995-10-18 |
| DD295848A5 (de) | 1991-11-14 |
| JPH03120277A (ja) | 1991-05-22 |
| HU206346B (en) | 1992-10-28 |
| DE59003446D1 (de) | 1993-12-16 |
| ATE97130T1 (de) | 1993-11-15 |
| PT95350A (pt) | 1991-05-22 |
| IE903369A1 (en) | 1991-04-10 |
| CZ278319B6 (en) | 1993-11-17 |
| ES2062313T3 (es) | 1994-12-16 |
| EP0418990B1 (de) | 1993-11-10 |
| HUT54682A (en) | 1991-03-28 |
| EP0418990A2 (de) | 1991-03-27 |
| CZ458290A3 (en) | 1993-04-14 |
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