NO20025030L - Makrosykliske NS3-serinproteaseinhibitorer for hepatitt C- virus, som omfatter alkyl- og arylalanin-P2-rester - Google Patents

Makrosykliske NS3-serinproteaseinhibitorer for hepatitt C- virus, som omfatter alkyl- og arylalanin-P2-rester

Info

Publication number
NO20025030L
NO20025030L NO20025030A NO20025030A NO20025030L NO 20025030 L NO20025030 L NO 20025030L NO 20025030 A NO20025030 A NO 20025030A NO 20025030 A NO20025030 A NO 20025030A NO 20025030 L NO20025030 L NO 20025030L
Authority
NO
Norway
Prior art keywords
arylalanine
macrocyclic
hepatitis
virus
residues
Prior art date
Application number
NO20025030A
Other languages
English (en)
Norwegian (no)
Other versions
NO20025030D0 (no
Inventor
Srikanth Venkatraman
Kevin X Chen
Ashok Arasappan
F George Njoroge
Viyyoor Moopil Girijavallabhan
Tin-Yau Chan
Brian A Mckittrick
Andrew J Prongay
Vincent Stewart Madison
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of NO20025030D0 publication Critical patent/NO20025030D0/no
Publication of NO20025030L publication Critical patent/NO20025030L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO20025030A 2000-04-19 2002-10-18 Makrosykliske NS3-serinproteaseinhibitorer for hepatitt C- virus, som omfatter alkyl- og arylalanin-P2-rester NO20025030L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19820400P 2000-04-19 2000-04-19
PCT/US2001/012530 WO2001081325A2 (en) 2000-04-19 2001-04-17 Macrocyclic ns3-serine protease inhibitors of hepatitis c virus comprising alkyl and aryl alanine p2 moieties

Publications (2)

Publication Number Publication Date
NO20025030D0 NO20025030D0 (no) 2002-10-18
NO20025030L true NO20025030L (no) 2002-12-18

Family

ID=22732422

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20025030A NO20025030L (no) 2000-04-19 2002-10-18 Makrosykliske NS3-serinproteaseinhibitorer for hepatitt C- virus, som omfatter alkyl- og arylalanin-P2-rester

Country Status (22)

Country Link
US (1) US6914122B2 (ja)
EP (1) EP1274724A2 (ja)
JP (1) JP4748912B2 (ja)
KR (1) KR20020097220A (ja)
CN (3) CN101580536A (ja)
AR (1) AR030558A1 (ja)
AU (1) AU2001253621A1 (ja)
BR (1) BR0110104A (ja)
CA (1) CA2406532A1 (ja)
CZ (1) CZ20023473A3 (ja)
HK (1) HK1048479A1 (ja)
HU (1) HUP0302957A2 (ja)
IL (1) IL151935A0 (ja)
MX (1) MXPA02010375A (ja)
NO (1) NO20025030L (ja)
NZ (1) NZ521456A (ja)
PE (1) PE20011288A1 (ja)
PL (1) PL358591A1 (ja)
RU (1) RU2002131163A (ja)
SK (1) SK14952002A3 (ja)
WO (1) WO2001081325A2 (ja)
ZA (1) ZA200208014B (ja)

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HK1048479A1 (zh) 2003-04-04
SK14952002A3 (sk) 2003-03-04
KR20020097220A (ko) 2002-12-31
NZ521456A (en) 2004-07-30
AU2001253621A1 (en) 2001-11-07
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MXPA02010375A (es) 2003-04-25
BR0110104A (pt) 2003-01-07
CA2406532A1 (en) 2001-11-01
PE20011288A1 (es) 2001-12-12
CN101580536A (zh) 2009-11-18
JP2003531199A (ja) 2003-10-21
CN1432022A (zh) 2003-07-23
IL151935A0 (en) 2003-04-10
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ZA200208014B (en) 2004-02-12
HUP0302957A2 (hu) 2003-12-29
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WO2001081325A2 (en) 2001-11-01
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AR030558A1 (es) 2003-08-27
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