NO20023247L - Purinderivater, fremgangsmate for deres fremstilling samt anvendelse derav - Google Patents
Purinderivater, fremgangsmate for deres fremstilling samt anvendelse deravInfo
- Publication number
- NO20023247L NO20023247L NO20023247A NO20023247A NO20023247L NO 20023247 L NO20023247 L NO 20023247L NO 20023247 A NO20023247 A NO 20023247A NO 20023247 A NO20023247 A NO 20023247A NO 20023247 L NO20023247 L NO 20023247L
- Authority
- NO
- Norway
- Prior art keywords
- purine derivatives
- processes
- preparation
- derivatives
- relates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
- C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Virology (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00200070 | 2000-01-07 | ||
PCT/EP2001/000150 WO2001049688A1 (en) | 2000-01-07 | 2001-01-08 | Purine derivatives, process for their preparation and use thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20023247D0 NO20023247D0 (no) | 2002-07-04 |
NO20023247L true NO20023247L (no) | 2002-09-09 |
Family
ID=8170897
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20023247A NO20023247L (no) | 2000-01-07 | 2002-07-04 | Purinderivater, fremgangsmate for deres fremstilling samt anvendelse derav |
Country Status (11)
Country | Link |
---|---|
US (1) | US20030187261A1 (no) |
EP (1) | EP1244668B1 (no) |
JP (1) | JP2003519232A (no) |
AT (1) | ATE322494T1 (no) |
AU (1) | AU3540101A (no) |
CA (1) | CA2396276A1 (no) |
CZ (1) | CZ20022353A3 (no) |
DE (1) | DE60118521T2 (no) |
IL (1) | IL150594A0 (no) |
NO (1) | NO20023247L (no) |
WO (1) | WO2001049688A1 (no) |
Families Citing this family (92)
Publication number | Priority date | Publication date | Assignee | Title |
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CZ27399A3 (cs) * | 1999-01-26 | 2000-08-16 | Ústav Experimentální Botaniky Av Čr | Substituované dusíkaté heterocyklické deriváty, způsob jejich přípravy, tyto deriváty pro použití jako léčiva, farmaceutická kompozice a kombinovaný farmaceutický přípravek tyto deriváty obsahující a použití těchto derivátů pro výrobu léčiv |
IL150062A0 (en) * | 1999-12-17 | 2002-12-01 | Ariad Pharma Inc | Proton pump inhibitors |
DK1377579T3 (da) * | 2000-10-31 | 2009-08-31 | Aventis Pharma Inc | Acyl- og sulfonylderivater af 6,9-disubstitueret-2(trans-1,4-diaminocyklohexyl)puriner og deres anvendelse som antiproliferative midler |
CZ294535B6 (cs) * | 2001-08-02 | 2005-01-12 | Ústav Experimentální Botaniky Avčr | Heterocyklické sloučeniny na bázi N6-substituovaného adeninu, způsoby jejich přípravy, jejich použití pro přípravu léčiv, kosmetických přípravků a růstových regulátorů, farmaceutické přípravky, kosmetické přípravky a růstové regulátory tyto sloučeniny obsahující |
GB0119249D0 (en) | 2001-08-07 | 2001-10-03 | Novartis Ag | Organic compounds |
US7323469B2 (en) | 2001-08-07 | 2008-01-29 | Novartis Ag | 7H-pyrrolo[2,3-d]pyrimidine derivatives |
ATE355291T1 (de) | 2001-12-18 | 2006-03-15 | Cv Therapeutics Inc | A2a adenosinrezeptorantagonisten |
EP1485390B1 (en) | 2002-03-07 | 2008-10-08 | F. Hoffman-la Roche AG | Bicyclic pyridine and pyrimidine p38 kinase inhibitors |
EP1485364B1 (en) | 2002-03-13 | 2009-03-11 | Janssen Pharmaceutica N.V. | Aminocarbonyl-derivatives as novel inhibitors of histone deacetylase |
EP1352910A1 (en) * | 2002-04-10 | 2003-10-15 | Grünenthal GmbH | New analogs of nitrobenzylthioinosine |
DE60304718T2 (de) | 2002-08-06 | 2007-04-26 | Astrazeneca Ab | Kondensierte pyridine und pyrimidine mit tie2 (tek) aktivität |
EP1444982A1 (de) * | 2003-02-06 | 2004-08-11 | Merckle Gmbh | Verwendung von Purinderivaten als selektive Kinase-Inhibitoren |
EP1620437B1 (en) | 2003-04-29 | 2009-06-17 | Pfizer Limited | 5,7-diaminopyrazolo¬4,3-d pyrimidines useful in the traetment of hypertension |
US7148228B2 (en) | 2003-09-18 | 2006-12-12 | Conforma Therapeutics Corporation | Pyrazolopyrimidines and related analogs as HSP90-inhibitors |
CA2535313C (en) * | 2003-09-25 | 2012-07-17 | Janssen Pharmaceutica N.V. | Hiv replication inhibiting purine derivatives |
US7572799B2 (en) * | 2003-11-24 | 2009-08-11 | Pfizer Inc | Pyrazolo[4,3-d]pyrimidines as Phosphodiesterase Inhibitors |
GB0327323D0 (en) * | 2003-11-24 | 2003-12-31 | Pfizer Ltd | Novel pharmaceuticals |
EP1697363A2 (en) * | 2003-12-16 | 2006-09-06 | Ranbaxy Laboratories Limited | Purine compounds which can be used as phosphodiesterase (pde) type iv inhibitors |
ES2350983T3 (es) * | 2003-12-30 | 2011-01-28 | Gilead Sciences, Inc. | Fosfonatos, monofosfonamidatos, bisfosfonamidatos para el tratamiento de enfermedades víricas. |
AU2005226359B2 (en) | 2004-03-26 | 2011-02-03 | Astrazeneca Aktiebolag | 9-substituted 8-oxoadenine compound |
DK1742950T3 (da) * | 2004-04-07 | 2009-03-16 | Pfizer Ltd | Pyrazolo-[4,3-D]-pyrimidiner |
PL1612210T3 (pl) * | 2004-06-29 | 2008-02-29 | Gruenenthal Gmbh | Nowe analogi nitrobenzylotioinozyny |
KR101261305B1 (ko) | 2004-07-28 | 2013-05-08 | 얀센 파마슈티카 엔.브이. | 히스톤 디아세틸라제의 신규한 저해제로의 치환된 인돌릴알킬 아미노 유도체 |
US7723340B2 (en) * | 2005-01-13 | 2010-05-25 | Signal Pharmaceuticals, Llc | Haloaryl substituted aminopurines, compositions thereof, and methods of treatment therewith |
US7759342B2 (en) * | 2005-01-13 | 2010-07-20 | Signal Pharmaceuticals, Llc | Methods of treatment and prevention using haloaryl substituted aminopurines |
US7521446B2 (en) | 2005-01-13 | 2009-04-21 | Signal Pharmaceuticals, Llc | Haloaryl substituted aminopurines, compositions thereof, and methods of treatment therewith |
AU2006205851A1 (en) | 2005-01-14 | 2006-07-20 | Janssen Pharmaceutica N.V. | 5-membered annelated heterocyclic pyrimidines as kinase inhibitors |
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US7538113B2 (en) | 2005-02-18 | 2009-05-26 | Wyeth | 4-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor |
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US7582634B2 (en) | 2005-02-18 | 2009-09-01 | Wyeth | 7-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor |
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KR20090109121A (ko) | 2007-02-07 | 2009-10-19 | 더 리전트 오브 더 유니버시티 오브 캘리포니아 | 합성 tlr 효능제의 접합체 및 그의 용도 |
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CA2713438A1 (en) * | 2008-02-07 | 2009-08-13 | The Regents Of The University Of California | Treatment of bladder diseases with a tlr7 activator |
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US8802684B2 (en) | 2008-08-11 | 2014-08-12 | Glaxosmithkline Llc | Adenine derivatives |
SG193149A1 (en) | 2008-08-11 | 2013-09-30 | Glaxosmithkline Llc | Novel adenine derivatives |
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UA103195C2 (uk) | 2008-08-11 | 2013-09-25 | Глаксосмитклайн Ллк | Похідні пурину для застосування у лікуванні алергій, запальних та інфекційних захворювань |
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US5302585A (en) * | 1990-04-20 | 1994-04-12 | Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic | Use of chiral 2-(phosphonomethoxy)propyl guanines as antiviral agents |
JPH05509307A (ja) * | 1990-07-19 | 1993-12-22 | ビーチャム・グループ・パブリック・リミテッド・カンパニー | プリンの抗ウイルス性ホスホノ―アルケン誘導体 |
US5208221A (en) * | 1990-11-29 | 1993-05-04 | Bristol-Myers Squibb Company | Antiviral (phosphonomethoxy) methoxy purine/pyrimidine derivatives |
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CZ284678B6 (cs) * | 1991-05-20 | 1999-01-13 | Ústav Organické Chemie A Biochemie Avčr | Di(2-propyl)estery 1-fluor-2-fosfonomethoxy-3-p -toluensulfonyloxypropanů, způsob jejich přípravy a použití |
US5849905A (en) * | 1994-11-23 | 1998-12-15 | Centre National De La Recherche Scientifique | Biologically active phosphotriester-type nucleosides and methods for preparing same |
CA2234609C (en) * | 1995-11-01 | 2006-11-28 | Novartis Ag | 2-amino-6-anilino-purine derivatives and processes for their preparation |
FR2741881B1 (fr) * | 1995-12-01 | 1999-07-30 | Centre Nat Rech Scient | Nouveaux derives de purine possedant notamment des prorietes anti-proliferatives et leurs applications biologiques |
CN1066448C (zh) * | 1996-06-06 | 2001-05-30 | 株式会社大塚制药工场 | 酰胺衍生物 |
US5866702A (en) * | 1996-08-02 | 1999-02-02 | Cv Therapeutics, Incorporation | Purine inhibitors of cyclin dependent kinase 2 |
CA2297967A1 (en) * | 1997-08-07 | 1999-02-18 | The Regents Of The University Of California | Purine inhibitor of protein kinases, g proteins and polymerases |
TR200002482T2 (tr) * | 1998-02-26 | 2002-10-21 | Aventis Pharmaceuticals Inc. | 6,9-Diikameli 2-(Trans-(4-Aminosiklohekzil) Amino)Pürinler |
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-
2001
- 2001-01-08 AT AT01907418T patent/ATE322494T1/de not_active IP Right Cessation
- 2001-01-08 JP JP2001550228A patent/JP2003519232A/ja active Pending
- 2001-01-08 WO PCT/EP2001/000150 patent/WO2001049688A1/en active IP Right Grant
- 2001-01-08 CZ CZ20022353A patent/CZ20022353A3/cs unknown
- 2001-01-08 CA CA002396276A patent/CA2396276A1/en not_active Abandoned
- 2001-01-08 US US10/169,592 patent/US20030187261A1/en not_active Abandoned
- 2001-01-08 DE DE60118521T patent/DE60118521T2/de not_active Expired - Lifetime
- 2001-01-08 EP EP01907418A patent/EP1244668B1/en not_active Expired - Lifetime
- 2001-01-08 IL IL15059401A patent/IL150594A0/xx unknown
- 2001-01-08 AU AU35401/01A patent/AU3540101A/en not_active Abandoned
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2002
- 2002-07-04 NO NO20023247A patent/NO20023247L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
JP2003519232A (ja) | 2003-06-17 |
US20030187261A1 (en) | 2003-10-02 |
WO2001049688A1 (en) | 2001-07-12 |
CZ20022353A3 (cs) | 2003-02-12 |
DE60118521D1 (de) | 2006-05-18 |
IL150594A0 (en) | 2003-02-12 |
WO2001049688A8 (en) | 2001-10-04 |
AU3540101A (en) | 2001-07-16 |
ATE322494T1 (de) | 2006-04-15 |
EP1244668A1 (en) | 2002-10-02 |
CA2396276A1 (en) | 2001-07-12 |
NO20023247D0 (no) | 2002-07-04 |
EP1244668B1 (en) | 2006-04-05 |
DE60118521T2 (de) | 2006-10-12 |
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