NL8900029A - Isochinoline-derivaten, hun bereiding en hun toepassing. - Google Patents
Isochinoline-derivaten, hun bereiding en hun toepassing. Download PDFInfo
- Publication number
- NL8900029A NL8900029A NL8900029A NL8900029A NL8900029A NL 8900029 A NL8900029 A NL 8900029A NL 8900029 A NL8900029 A NL 8900029A NL 8900029 A NL8900029 A NL 8900029A NL 8900029 A NL8900029 A NL 8900029A
- Authority
- NL
- Netherlands
- Prior art keywords
- dimethoxy
- phenyl
- formula
- isoquinoline
- acid addition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
- C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8800397 | 1988-01-08 | ||
| GB888800397A GB8800397D0 (en) | 1988-01-08 | 1988-01-08 | Improvements in/relating to organic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NL8900029A true NL8900029A (nl) | 1989-08-01 |
Family
ID=10629678
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL8900029A NL8900029A (nl) | 1988-01-08 | 1989-01-06 | Isochinoline-derivaten, hun bereiding en hun toepassing. |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US4980359A (it) |
| JP (1) | JPH0649686B2 (it) |
| KR (1) | KR0142686B1 (it) |
| AT (1) | AT394365B (it) |
| AU (1) | AU622429B2 (it) |
| BE (1) | BE1002730A3 (it) |
| CA (1) | CA1332944C (it) |
| CH (1) | CH678727A5 (it) |
| DE (1) | DE3900233C2 (it) |
| DK (1) | DK5789A (it) |
| ES (1) | ES2010071A6 (it) |
| FI (1) | FI90865C (it) |
| FR (1) | FR2625743B1 (it) |
| GB (2) | GB8800397D0 (it) |
| GR (1) | GR1002750B (it) |
| HU (1) | HU205083B (it) |
| IE (1) | IE61914B1 (it) |
| IL (1) | IL88899A (it) |
| IT (1) | IT1229523B (it) |
| LU (1) | LU87423A1 (it) |
| MY (1) | MY103963A (it) |
| NL (1) | NL8900029A (it) |
| NZ (1) | NZ227561A (it) |
| PH (1) | PH25640A (it) |
| PL (1) | PL156099B1 (it) |
| PT (1) | PT89405B (it) |
| SE (1) | SE501548C2 (it) |
| ZA (1) | ZA89133B (it) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2723674A (en) * | 1951-11-28 | 1955-11-15 | Charles E Harris | Telephone cableman's tent |
| US3007541A (en) * | 1959-02-24 | 1961-11-07 | Jr John B Mast | Temporary covering and support structure therefor |
| GB8807922D0 (en) * | 1988-04-05 | 1988-05-05 | Fujisawa Pharmaceutical Co | Isoquinoline compound & process for preparation thereof |
| US4956371A (en) * | 1989-09-19 | 1990-09-11 | Euroceltique, S.A. | Substituted isoquinolines and methods of using same |
| GB8921304D0 (en) * | 1989-09-20 | 1989-11-08 | Wyeth John & Brother Ltd | New method of treatment and heterocyclic compounds used therein |
| GB9027055D0 (en) * | 1990-12-13 | 1991-02-06 | Sandoz Ltd | Organic compounds |
| KR930703259A (ko) * | 1990-12-17 | 1993-11-29 | 알베르투스 빌헬무스 요아네스 쩨스트라텐 | 살균성 이소퀴놀린 유도체 |
| CA2093577C (en) * | 1992-05-07 | 2006-01-03 | Michael Klaus | Alkyl or alkoxy substituted s-heterocyclic retinoids |
| US5350423A (en) * | 1992-09-23 | 1994-09-27 | Burlington Industries Inc. | Fabric finishing procedure |
| GB9322828D0 (en) * | 1993-11-05 | 1993-12-22 | Sandoz Ltd | Organic compounds |
| US7399837B2 (en) | 1995-12-22 | 2008-07-15 | Smithkline Beecham Corporation | Recombinant IL-5 antagonists useful in treatment of IL-5 mediated disorders |
| US5783184A (en) * | 1994-12-23 | 1998-07-21 | Smithkline Beecham Corporation | Method for treatment and diagnosis of IL-5 mediated disorders |
| US5693323A (en) * | 1994-12-23 | 1997-12-02 | Smithkline Beecham Corporation | Recombinant IL-5 antagonists useful in treatment of IL-5 mediated disorders |
| ATE346867T1 (de) * | 1994-12-23 | 2006-12-15 | Smithkline Beecham Corp | Rekombinante il-5 antagonisten für die behandlung von il-5 bedingten krankheiten |
| GB9622386D0 (en) * | 1996-10-28 | 1997-01-08 | Sandoz Ltd | Organic compounds |
| IT1296985B1 (it) * | 1997-12-19 | 1999-08-03 | Zambon Spa | Derivati benzazinici inibitori della fosfodiesterasi 4 |
| ATE356810T1 (de) * | 1999-01-15 | 2007-04-15 | Altana Pharma Ag | Polysubstituted 6-phenylphenanthridines mit pde- iv hemmender wirkung |
| PT1212089E (pt) | 1999-08-21 | 2006-08-31 | Altana Pharma Ag | Combinacao sinergica de roflumilast e salmeterol |
| JP2006522151A (ja) | 2003-04-01 | 2006-09-28 | アプライド リサーチ システムズ エーアールエス ホールディング ナームロゼ フェンノートシャップ | 不妊症におけるホスホジエステラーゼ阻害剤 |
| US20100086554A1 (en) * | 2007-04-30 | 2010-04-08 | Smithkline Beecham Corporation | Methods for administering anti-il-5 antibodies |
| AU2009228163B2 (en) | 2008-03-28 | 2012-08-30 | Glaxosmithkline Llc | Methods of treatment |
| JP6265583B2 (ja) | 2008-10-17 | 2018-01-24 | ウィスコンシン アルムニ リサーチ ファンデイション | 生理活性アルファベータペプチドを作製する方法 |
| BR112019025736A2 (pt) | 2017-06-06 | 2020-06-30 | Glaxosmithkline Llc | uso de um anticorpo e composições para tratar uma doença e para diminuir uma contagem absoluta de eosinófilo no sangue |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB645139A (en) * | 1946-10-22 | 1950-10-25 | Servita Gyogyszeryar Es Vegyip | Improved process for the production of isoquinoline derivatives |
| DE1184344B (de) * | 1962-06-16 | 1964-12-31 | Orgamol Sa | Verfahren zur Herstellung von Isochinolinderivaten |
| US3878215A (en) * | 1971-12-01 | 1975-04-15 | Sandoz Ag | 2-Alkyl-3-substituted-4-aryl isoquinolines |
| DE2401453A1 (de) * | 1973-01-16 | 1974-07-18 | John James Voorhees | Pharmazeutische zusammensetzung zur behandlung von hautproliferationserkrankungen |
| US4018927A (en) * | 1973-12-17 | 1977-04-19 | The Regents Of The University Of Michigan | Treatment of proliferating skin diseases with papaverine alkaloids |
| FI750205A (it) * | 1974-02-05 | 1975-08-06 | Sandoz Ag | |
| DE2811361A1 (de) * | 1978-03-16 | 1979-09-27 | Hoechst Ag | Neue isochinolinaldehyde und verfahren zu ihrer herstellung |
| DE3244594A1 (de) * | 1982-12-02 | 1984-06-07 | Hoechst Ag, 6230 Frankfurt | 1-phenylisochinolinderivate und verfahren zu ihrer herstellung, diese verbindung enthaltende pharmazeutische praeparate und deren anwendung |
| HU196758B (en) * | 1986-05-21 | 1989-01-30 | Gyogyszerkutato Intezet | Process for production of 3-hidroxi-methil-quinolines and medical compositions containing them |
| CA1330560C (en) * | 1986-05-21 | 1994-07-05 | Maurits E. A. Vandewalle | Di- and tetrahydroisoquinoline derivatives |
-
1988
- 1988-01-08 GB GB888800397A patent/GB8800397D0/en active Pending
-
1989
- 1989-01-03 HU HU8911A patent/HU205083B/hu not_active IP Right Cessation
- 1989-01-04 IT IT8947504A patent/IT1229523B/it active
- 1989-01-04 GB GB8900102A patent/GB2213482B/en not_active Expired - Lifetime
- 1989-01-05 DE DE3900233A patent/DE3900233C2/de not_active Expired - Fee Related
- 1989-01-05 CA CA000587599A patent/CA1332944C/en not_active Expired - Fee Related
- 1989-01-05 ES ES8900053A patent/ES2010071A6/es not_active Expired
- 1989-01-05 SE SE8900039A patent/SE501548C2/sv unknown
- 1989-01-06 FR FR898900128A patent/FR2625743B1/fr not_active Expired - Lifetime
- 1989-01-06 MY MYPI89000013A patent/MY103963A/en unknown
- 1989-01-06 BE BE8900018A patent/BE1002730A3/fr not_active IP Right Cessation
- 1989-01-06 AU AU27795/89A patent/AU622429B2/en not_active Ceased
- 1989-01-06 PH PH38011A patent/PH25640A/en unknown
- 1989-01-06 PT PT89405A patent/PT89405B/pt not_active IP Right Cessation
- 1989-01-06 NL NL8900029A patent/NL8900029A/nl not_active Application Discontinuation
- 1989-01-06 FI FI890072A patent/FI90865C/fi not_active IP Right Cessation
- 1989-01-06 LU LU87423A patent/LU87423A1/fr unknown
- 1989-01-06 PL PL1989277092A patent/PL156099B1/pl unknown
- 1989-01-06 IL IL8889989A patent/IL88899A/en not_active IP Right Cessation
- 1989-01-06 ZA ZA89133A patent/ZA89133B/xx unknown
- 1989-01-06 DK DK005789A patent/DK5789A/da not_active Application Discontinuation
- 1989-01-06 JP JP1001898A patent/JPH0649686B2/ja not_active Expired - Lifetime
- 1989-01-06 IE IE3789A patent/IE61914B1/en not_active IP Right Cessation
- 1989-01-06 NZ NZ227561A patent/NZ227561A/xx unknown
- 1989-01-07 KR KR1019890000151A patent/KR0142686B1/ko not_active IP Right Cessation
- 1989-01-09 GR GR890100008A patent/GR1002750B/el unknown
- 1989-01-09 AT AT0003589A patent/AT394365B/de not_active IP Right Cessation
- 1989-01-09 CH CH59/89A patent/CH678727A5/de not_active IP Right Cessation
-
1990
- 1990-04-10 US US07/507,702 patent/US4980359A/en not_active Expired - Fee Related
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BV | The patent application has lapsed | ||
| BA | A request for search or an international-type search has been filed | ||
| BB | A search report has been drawn up | ||
| BC | A request for examination has been filed | ||
| CNR | Transfer of rights (patent application after its laying open for public inspection) |
Free format text: NOVARTIS AG |
|
| BV | The patent application has lapsed |