MY191669A - Pyrazolyl quinoxaline kinase inihibitors - Google Patents

Pyrazolyl quinoxaline kinase inihibitors

Info

Publication number
MY191669A
MY191669A MYPI2016001863A MYPI2016001863A MY191669A MY 191669 A MY191669 A MY 191669A MY PI2016001863 A MYPI2016001863 A MY PI2016001863A MY PI2016001863 A MYPI2016001863 A MY PI2016001863A MY 191669 A MY191669 A MY 191669A
Authority
MY
Malaysia
Prior art keywords
inihibitors
compounds
pyrazolyl
kinase
quinoxaline kinase
Prior art date
Application number
MYPI2016001863A
Other languages
English (en)
Inventor
Lieven Meerpoel
Werner Constant Johan Embrechts
Johan Erwin Edmond Weerts
Jean Fernand Armand Lacrampe
Gordon Saxty
Christopher William Murray
Valerio Berdini
Gilbert Ebai Besong
Christopher Charles Frederick Hamlett
Christopher Norbert Johnson
Steven John Woodhead
Michael Reader
David Charles Rees
Laurence Anne Mevellec
Patrick Rene Angibaud
Eddy Jean Edgard Freyne
Tom Cornelis Hortense Govaerts
Timothy Pietro Suren Perera
Ronaldus Arnodus Hendrika Joseph Gilissen
Berthold Wroblowski
Alexandra Papanikos
Oliver Alexis Georges Querolle
Elisabeth Therese Jeanne Pasquier
Isabelle Noelle Constance Pilatte
Pascal Ghislain Andre Bonnet
Rhalid Akkari
Original Assignee
Astex Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astex Therapeutics Ltd filed Critical Astex Therapeutics Ltd
Publication of MY191669A publication Critical patent/MY191669A/en

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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • C07—ORGANIC CHEMISTRY
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    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C07D491/113—Spiro-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6524—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Immunology (AREA)
  • Psychology (AREA)
  • Otolaryngology (AREA)
  • Psychiatry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hospice & Palliative Care (AREA)
MYPI2016001863A 2010-04-30 2011-04-28 Pyrazolyl quinoxaline kinase inihibitors MY191669A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32988410P 2010-04-30 2010-04-30
GB201007286A GB201007286D0 (en) 2010-04-30 2010-04-30 New compounds

Publications (1)

Publication Number Publication Date
MY191669A true MY191669A (en) 2022-07-06

Family

ID=42289929

Family Applications (2)

Application Number Title Priority Date Filing Date
MYPI2012004699A MY189427A (en) 2010-04-30 2011-04-28 Pyrazolyl quinoxaline kinase inhibitors
MYPI2016001863A MY191669A (en) 2010-04-30 2011-04-28 Pyrazolyl quinoxaline kinase inihibitors

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MYPI2012004699A MY189427A (en) 2010-04-30 2011-04-28 Pyrazolyl quinoxaline kinase inhibitors

Country Status (41)

Country Link
US (6) US8895601B2 (index.php)
EP (3) EP3178818B1 (index.php)
JP (1) JP5639261B2 (index.php)
KR (2) KR101933843B1 (index.php)
CN (2) CN102858765B (index.php)
AP (1) AP3210A (index.php)
AR (1) AR080982A1 (index.php)
AU (2) AU2011247047B2 (index.php)
BR (1) BR112012027509B1 (index.php)
CA (1) CA2796204C (index.php)
CL (1) CL2012003048A1 (index.php)
CR (2) CR20180339A (index.php)
CY (2) CY1121882T1 (index.php)
DK (3) DK2563775T3 (index.php)
EA (2) EA028599B1 (index.php)
EC (1) ECSP12012318A (index.php)
ES (3) ES2621461T3 (index.php)
FI (1) FIC20250009I1 (index.php)
FR (1) FR25C1006I1 (index.php)
GB (1) GB201007286D0 (index.php)
HR (1) HRP20211675T1 (index.php)
HU (4) HUE056999T2 (index.php)
IL (1) IL222600A (index.php)
IN (1) IN2012MN02591A (index.php)
JO (1) JO3366B1 (index.php)
LT (4) LT2563775T (index.php)
ME (1) ME01825B (index.php)
MX (2) MX365702B (index.php)
MY (2) MY189427A (index.php)
NL (1) NL301318I2 (index.php)
NO (1) NO2025011I1 (index.php)
NZ (1) NZ602726A (index.php)
PH (1) PH12012501993A1 (index.php)
PL (3) PL2563775T3 (index.php)
PT (3) PT3590934T (index.php)
RS (3) RS55863B1 (index.php)
SG (2) SG184966A1 (index.php)
SI (3) SI3590934T1 (index.php)
SM (3) SMT201900469T1 (index.php)
TW (1) TWI545122B (index.php)
WO (1) WO2011135376A1 (index.php)

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