MX391454B - Compuesto de engarce-fármaco para conjugación a una unidad de ligando. - Google Patents

Compuesto de engarce-fármaco para conjugación a una unidad de ligando.

Info

Publication number
MX391454B
MX391454B MX2016002200A MX2016002200A MX391454B MX 391454 B MX391454 B MX 391454B MX 2016002200 A MX2016002200 A MX 2016002200A MX 2016002200 A MX2016002200 A MX 2016002200A MX 391454 B MX391454 B MX 391454B
Authority
MX
Mexico
Prior art keywords
conjugation
drug
linker compound
ligand unit
pbds
Prior art date
Application number
MX2016002200A
Other languages
English (en)
Spanish (es)
Inventor
Patrick Burke
Peter Senter
Philip Wilson Howard
Scott Jeffrey
Original Assignee
Seagen Inc
Medimmune Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seagen Inc, Medimmune Ltd filed Critical Seagen Inc
Publication of MX391454B publication Critical patent/MX391454B/es

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    • C07D519/06—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00 containing at least one condensed beta-lactam ring system, provided for by groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00, e.g. a penem or a cepham system
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    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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IL252864A0 (en) 2017-08-31
US20160129013A1 (en) 2016-05-12
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