MX341825B - Compuestos de heteroarilo y usos de los mismos. - Google Patents

Compuestos de heteroarilo y usos de los mismos.

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Publication number
MX341825B
MX341825B MX2014015883A MX2014015883A MX341825B MX 341825 B MX341825 B MX 341825B MX 2014015883 A MX2014015883 A MX 2014015883A MX 2014015883 A MX2014015883 A MX 2014015883A MX 341825 B MX341825 B MX 341825B
Authority
MX
Mexico
Prior art keywords
heteroaryl compounds
compounds
methods
pharmaceutically acceptable
heteroaryl
Prior art date
Application number
MX2014015883A
Other languages
English (en)
Inventor
F Kluge Arthur
Wayne Tester Richland
Qiao Lixin
Niu Deqiang
Singh Juswinder
Mazdiyasni Hormoz
Petter Russell
Frederick Westlin William Iii
Original Assignee
Avila Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avila Therapeutics Inc filed Critical Avila Therapeutics Inc
Publication of MX341825B publication Critical patent/MX341825B/es

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    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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Abstract

La presente invención se refiere a inhibidores de proteína cinasas de las fórmulas I-a e I-b, composiciones farmacéuticamente aceptables de los mismos, y método para usar los mismos.
MX2014015883A 2009-12-29 2010-12-29 Compuestos de heteroarilo y usos de los mismos. MX341825B (es)

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