MX337589B - Extracto de planta, composiciones que contienen el mismo, metodo de extraccion y usos del mismo. - Google Patents
Extracto de planta, composiciones que contienen el mismo, metodo de extraccion y usos del mismo.Info
- Publication number
- MX337589B MX337589B MX2012003241A MX2012003241A MX337589B MX 337589 B MX337589 B MX 337589B MX 2012003241 A MX2012003241 A MX 2012003241A MX 2012003241 A MX2012003241 A MX 2012003241A MX 337589 B MX337589 B MX 337589B
- Authority
- MX
- Mexico
- Prior art keywords
- extract
- extraction
- plant extract
- containing same
- plant
- Prior art date
Links
- 238000000605 extraction Methods 0.000 title abstract 2
- 239000000419 plant extract Substances 0.000 title abstract 2
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 abstract 2
- 208000003351 Melanosis Diseases 0.000 abstract 2
- 239000000284 extract Substances 0.000 abstract 2
- 206010008570 Chloasma Diseases 0.000 abstract 1
- 241000196324 Embryophyta Species 0.000 abstract 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 241000218213 Morus <angiosperm> Species 0.000 abstract 1
- 240000000249 Morus alba Species 0.000 abstract 1
- 235000008708 Morus alba Nutrition 0.000 abstract 1
- 208000012641 Pigmentation disease Diseases 0.000 abstract 1
- 206010040925 Skin striae Diseases 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- -1 imino sugars Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 201000001441 melanoma Diseases 0.000 abstract 1
- 230000019612 pigmentation Effects 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 235000000346 sugar Nutrition 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/318—Foods, ingredients or supplements having a functional effect on health having an effect on skin health and hair or coat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Abstract
La presente invención se refiere a un extracto vegetal obtenido de las hojas de planta de Morus que tiene valor IC50, de menos de 90 µg/ml con respecto a la inhibición de ?-glucosidasa I, caracterizado porque comprende: 5-40% (peso/peso) de imino azucares totales, cuando es medido por al menos una de cromatografía de líquidos de alto rendimiento (HPLC) cuantitativa y/o cromatografía de líquidos/espectrometría de masas (LC-MS) , incluyendo al menos uno de 1-desoxinojirimicina (DNJ), fagomina, y N-metil-DNJ; y 20-70% (peso/peso) de aminoácidos totales, en donde el extracto es amarillo pálido o casi blanco y es fácilmente soluble en agua; en donde los pasos para preparar el extracto vegetal comprenden: a. someter material de hoja de planta Morus a un paso de extracción acuosa o alcohólica para obtener un extracto crudo; b. someter el extracto crudo un paso de purificación por cromatografía en columna mediante el uso de una resina de intercambio catiónico de ácido fuerte, lavar la columna con agua, eluir la columna con una solución de amoniaco recogiendo después el eluyente y eliminando el amoniaco del mismo.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN200910307065XA CN102018766B (zh) | 2009-09-16 | 2009-09-16 | 一种植物提取物、其提取方法和用途及含有这种提取物的组合物 |
PCT/CN2010/076988 WO2011032502A1 (en) | 2009-09-16 | 2010-09-16 | Plant extract, compositons containing same, method of extraction and uses thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2012003241A MX2012003241A (es) | 2012-08-23 |
MX337589B true MX337589B (es) | 2016-03-11 |
Family
ID=43758116
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2012003241A MX337589B (es) | 2009-09-16 | 2010-09-16 | Extracto de planta, composiciones que contienen el mismo, metodo de extraccion y usos del mismo. |
Country Status (17)
Country | Link |
---|---|
US (5) | US8980343B2 (es) |
EP (1) | EP2477639B1 (es) |
JP (4) | JP2013504607A (es) |
KR (2) | KR20120100918A (es) |
CN (3) | CN102018766B (es) |
AU (1) | AU2010294983B2 (es) |
BR (1) | BR112012006001A2 (es) |
CA (1) | CA2774313C (es) |
DK (1) | DK2477639T3 (es) |
EA (1) | EA027471B1 (es) |
ES (1) | ES2861225T3 (es) |
IN (1) | IN2012DN03153A (es) |
MX (1) | MX337589B (es) |
MY (1) | MY173506A (es) |
PL (1) | PL2477639T3 (es) |
SG (1) | SG179168A1 (es) |
WO (1) | WO2011032502A1 (es) |
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CN102018766B (zh) * | 2009-09-16 | 2013-03-06 | 博仲盛景医药技术(北京)有限公司 | 一种植物提取物、其提取方法和用途及含有这种提取物的组合物 |
CN102735782A (zh) * | 2011-04-12 | 2012-10-17 | 中国科学院长春应用化学研究所 | 一种筛选α-葡萄糖苷酶抑制剂的方法 |
JP5806859B2 (ja) * | 2011-06-08 | 2015-11-10 | ポーラ化成工業株式会社 | スクリーニング方法 |
GB2496388B (en) | 2011-11-08 | 2014-10-08 | Phynova Ltd | Morus extracts rich in n-acids of imino sugars and or pipecolic acids |
CN102600245A (zh) * | 2012-04-20 | 2012-07-25 | 南开大学 | 桑枝皮中具有抑制α-糖苷酶活性的水溶性生物碱纯化方法及应用 |
CN102670437B (zh) * | 2012-04-23 | 2013-07-10 | 浙江省农业科学院 | 一种桑叶清凉痘消液及其制备工艺 |
US9897565B1 (en) | 2012-09-11 | 2018-02-20 | Aseko, Inc. | System and method for optimizing insulin dosages for diabetic subjects |
US9171343B1 (en) | 2012-09-11 | 2015-10-27 | Aseko, Inc. | Means and method for improved glycemic control for diabetic patients |
US9486580B2 (en) | 2014-01-31 | 2016-11-08 | Aseko, Inc. | Insulin management |
US9233204B2 (en) | 2014-01-31 | 2016-01-12 | Aseko, Inc. | Insulin management |
US11081226B2 (en) | 2014-10-27 | 2021-08-03 | Aseko, Inc. | Method and controller for administering recommended insulin dosages to a patient |
EP3050023B1 (en) | 2014-10-27 | 2021-08-25 | Aseko, Inc. | Subcutaneous outpatient management |
CN105055206A (zh) * | 2015-07-28 | 2015-11-18 | 浙江省农业科学院 | 一种桑枝祛黄补水润肤霜及其制备工艺 |
CA2993275C (en) | 2015-08-20 | 2022-06-21 | Aseko, Inc. | Diabetes management therapy advisor |
CN105168262A (zh) * | 2015-10-22 | 2015-12-23 | 河南行知专利服务有限公司 | 一种含糖类化合物的中药免煎剂的制备方法 |
CN105267739A (zh) * | 2015-10-23 | 2016-01-27 | 戚炎月 | 淡斑祛斑胶囊 |
CN105902444A (zh) * | 2016-06-12 | 2016-08-31 | 马殿伟 | 一种含有毗黎勒果的用于化妆品的美白中药组合物 |
CN105919828B (zh) * | 2016-07-07 | 2019-06-21 | 广州莱丽奇生物科技有限公司 | 一种美白淡斑组合物、制备方法及其应用 |
CN109641024B (zh) * | 2016-07-19 | 2022-03-25 | 嘉康利公司 | 具有低含量缩合鞣质分子的麝香葡萄局部组合物 |
CN107192777A (zh) * | 2017-05-24 | 2017-09-22 | 江苏耐雀生物工程技术有限公司 | 一种桑叶提取物中1‑脱氧野尻霉素含量的检测方法 |
CN107281258B (zh) * | 2017-07-19 | 2020-12-11 | 浙江大学 | 一种豆芋叶黄酮类提取物及其制备方法和应用 |
JP2019127439A (ja) * | 2018-01-22 | 2019-08-01 | 株式会社お茶村 | 桑葉を含むサプリメント |
CN108261346B (zh) * | 2018-03-01 | 2020-12-29 | 上海科颜生物科技有限公司 | 一种美白组合物及其制备方法 |
JP6651666B1 (ja) * | 2019-04-04 | 2020-02-19 | サントリーホールディングス株式会社 | 1−デオキシノジリマイシンを含む容器詰飲料 |
CN110393738B (zh) * | 2019-08-27 | 2022-09-20 | 北京五和博澳药业股份有限公司 | 一种植物提取方法 |
WO2021119664A1 (en) | 2019-12-10 | 2021-06-17 | Mary Kay Inc. | Herbal cosmetic composition for treating skin |
CN111024868B (zh) * | 2020-01-02 | 2022-06-03 | 华润三九医药股份有限公司 | 一种白树药材中α-高野尻霉素的含量检测方法 |
CN111812252B (zh) * | 2020-08-25 | 2023-03-31 | 山东省分析测试中心 | 一种对植物中降糖功能化合物的筛选及分离方法 |
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CN115219613B (zh) * | 2022-06-16 | 2023-12-22 | 上海市食品药品检验研究院 | 一种化妆品中壬二酸和壬二酰二甘氨酸钾的检测方法 |
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2009
- 2009-09-16 CN CN200910307065XA patent/CN102018766B/zh active Active
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2010
- 2010-09-16 PL PL10816706T patent/PL2477639T3/pl unknown
- 2010-09-16 ES ES10816706T patent/ES2861225T3/es active Active
- 2010-09-16 MY MYPI2012001118A patent/MY173506A/en unknown
- 2010-09-16 DK DK10816706.5T patent/DK2477639T3/da active
- 2010-09-16 US US13/496,427 patent/US8980343B2/en active Active
- 2010-09-16 KR KR1020127009739A patent/KR20120100918A/ko active Application Filing
- 2010-09-16 JP JP2012529114A patent/JP2013504607A/ja active Pending
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