MX2021011687A - Composiciones inmunogenicas y vacunas que comprenden peptidos y proteinas del virus de la peste porcina africana y usos de las mismas. - Google Patents

Composiciones inmunogenicas y vacunas que comprenden peptidos y proteinas del virus de la peste porcina africana y usos de las mismas.

Info

Publication number
MX2021011687A
MX2021011687A MX2021011687A MX2021011687A MX2021011687A MX 2021011687 A MX2021011687 A MX 2021011687A MX 2021011687 A MX2021011687 A MX 2021011687A MX 2021011687 A MX2021011687 A MX 2021011687A MX 2021011687 A MX2021011687 A MX 2021011687A
Authority
MX
Mexico
Prior art keywords
vaccines
fever virus
swine fever
proteins
african swine
Prior art date
Application number
MX2021011687A
Other languages
English (en)
Inventor
Egbert Siegfried Mundt
Veljko Nikolin
González Fernando Rodriguez
Camós Laia Bosch
Miguens Javier Alonso Collado
Original Assignee
Boehringer Ingelheim Vetmedica Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Vetmedica Gmbh filed Critical Boehringer Ingelheim Vetmedica Gmbh
Publication of MX2021011687A publication Critical patent/MX2021011687A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/01DNA viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/746Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/542Mucosal route oral/gastrointestinal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/543Mucosal route intranasal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/12011Asfarviridae
    • C12N2710/12022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/12011Asfarviridae
    • C12N2710/12034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Abstract

La presente invención se refiere a péptidos y/o polipéptidos del virus de la peste porcina africana (ASFV) así como a fragmentos inmunogénicos de los mismos, oligonucleótidos y/o polinucleótidos de AFSV codificadores correspondientes, así como a fragmentos inmunogénicos de los mismos, composiciones inmunogénicas, vacunas y usos de los mismos.
MX2021011687A 2019-03-27 2020-03-26 Composiciones inmunogenicas y vacunas que comprenden peptidos y proteinas del virus de la peste porcina africana y usos de las mismas. MX2021011687A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP19382216 2019-03-27
PCT/EP2020/058498 WO2020193688A2 (en) 2019-03-27 2020-03-26 Immunogenic compositions and vaccines comprising african swine fever virus peptides and proteins and uses thereof

Publications (1)

Publication Number Publication Date
MX2021011687A true MX2021011687A (es) 2021-10-22

Family

ID=66175370

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2021011687A MX2021011687A (es) 2019-03-27 2020-03-26 Composiciones inmunogenicas y vacunas que comprenden peptidos y proteinas del virus de la peste porcina africana y usos de las mismas.

Country Status (11)

Country Link
US (2) US11628214B2 (es)
EP (1) EP3946445A2 (es)
JP (1) JP2022525920A (es)
KR (1) KR20210145221A (es)
CN (1) CN113543801A (es)
AU (1) AU2020247131A1 (es)
CA (1) CA3130664A1 (es)
EA (1) EA202192570A1 (es)
MX (1) MX2021011687A (es)
TW (1) TW202102258A (es)
WO (1) WO2020193688A2 (es)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202102258A (zh) * 2019-03-27 2021-01-16 德商百靈佳殷格翰維美迪加股份有限公司 含有非洲豬瘟病毒肽及蛋白之免疫原組合物及疫苗以及其用途
CN111499697A (zh) * 2020-04-08 2020-08-07 中国农业科学院哈尔滨兽医研究所(中国动物卫生与流行病学中心哈尔滨分中心) 一种非洲猪瘟病毒p54重组蛋白的间接ELISA抗体检测试剂盒及其制备方法
CN111735943A (zh) * 2020-06-04 2020-10-02 中国热带农业科学院热带作物品种资源研究所 一种能够同步检测猪血中非洲猪瘟病毒抗原和抗体的试剂盒及检测方法
CN112481220B (zh) * 2020-11-03 2021-09-14 中国农业科学院兰州兽医研究所 抗非洲猪瘟病毒解旋酶d1133l单克隆抗体、分泌该单克隆抗体的杂交瘤细胞株及应用
CN112472801A (zh) * 2020-12-22 2021-03-12 华南农业大学 非洲猪瘟p30、p54、p72和B602L的DNA疫苗和亚单位疫苗及其制备方法与应用
MX2023007633A (es) * 2020-12-24 2023-07-14 Intervet Int B V Inmunoensayo diva de la fiebre porcina africana.
CN112704731B (zh) * 2021-01-13 2023-08-25 中国农业科学院哈尔滨兽医研究所(中国动物卫生与流行病学中心哈尔滨分中心) 蛋白酶s273r抑制细胞焦亡的用途及方法
CN112852761B (zh) * 2021-03-08 2022-08-23 中国农业科学院兰州兽医研究所 基因缺失减毒非洲猪瘟病毒株的构建及作为疫苗的应用
CN115074372A (zh) * 2021-03-10 2022-09-20 浙江海隆生物科技有限公司 一种重组的非洲猪瘟病毒j18l亚单位蛋白及其制备方法和应用
CN114392345B (zh) * 2021-03-11 2023-08-25 中国农业科学院哈尔滨兽医研究所(中国动物卫生与流行病学中心哈尔滨分中心) E199l蛋白在促进细胞凋亡中的用途及方法
BR112023019349A2 (pt) * 2021-03-22 2024-02-15 Igy Immune Tech And Life Sciences Inc Método para produzir uma composição oralmente administrável, forma de dosagem unitária, composição de vacina, usos, kit e produto alimentício ou composição alimentícia
CN113122511B (zh) * 2021-04-13 2021-11-19 金宇保灵生物药品有限公司 一种基因缺失的减毒非洲猪瘟病毒毒株及其构建方法和应用
CN113735943A (zh) * 2021-05-13 2021-12-03 浙江海隆生物科技有限公司 一种重组的非洲猪瘟病毒p72亚单位蛋白和制备方法及其应用
CN113061588B (zh) * 2021-05-20 2023-08-01 军事科学院军事医学研究院军事兽医研究所 缺失i226r基因的非洲猪瘟病毒减毒株及其活疫苗
CN113528578A (zh) * 2021-05-25 2021-10-22 华南农业大学 一种表达非洲猪瘟o61r蛋白的重组杆状病毒及其用途
US11801296B2 (en) 2021-06-30 2023-10-31 The United States Of America, As Represented By The Secretary Of Agriculture Development of a novel live attenuated African swine fever vaccine based in the deletion of gene A137R
CN113502352B (zh) * 2021-07-01 2022-02-01 华中农业大学 检测具有感染性ASFV的EMA-ddPCR引物、探针及应用
CN113308422A (zh) * 2021-07-30 2021-08-27 山东格研生物技术有限公司 一种博兹曼军团菌分离培养基及其制备方法
CN113717945B (zh) * 2021-08-02 2023-08-11 河南农业大学 分泌抗非洲猪瘟病毒e165r蛋白单克隆抗体的杂交瘤细胞株、抗体、抗原表位肽及应用
CN114272365B (zh) * 2021-09-15 2024-02-23 中国农业科学院上海兽医研究所(中国动物卫生与流行病学中心上海分中心) 一种基因缺失的减毒非洲猪瘟病毒构建及其作为疫苗的应用
CN113786480B (zh) * 2021-09-16 2023-12-22 福建农林大学 非洲猪瘟病毒a137r和k205r基因的应用
CN114410587A (zh) * 2021-09-23 2022-04-29 中国农业科学院兰州兽医研究所 一种提高非洲猪瘟病毒非靶细胞ma-104细胞系感染滴度的方法
CN114107228B (zh) * 2021-11-11 2023-06-13 中国农业科学院兰州兽医研究所 缺失十二个基因的减毒非洲猪瘟病毒株的构建及其作为疫苗的应用
CN114058642A (zh) * 2021-11-26 2022-02-18 中国农业科学院北京畜牧兽医研究所 表达非洲猪瘟病毒ep153r-ep402r蛋白的重组腺病毒及构建方法
CN113831394B (zh) * 2021-11-29 2022-04-12 中国人民解放军军事科学院军事医学研究院 一种非洲猪瘟病毒asfv基因的重组病毒组合及由其制备的疫苗
CN114164300B (zh) * 2021-12-18 2023-10-31 扬州大学 一种可快速鉴别ASFV基因I型与基因II型的iiPCR试剂盒及其使用方法
CN114409742B (zh) * 2021-12-27 2023-07-21 中国农业科学院兰州兽医研究所 非洲猪瘟病毒p49蛋白抗原表位及其应用
CN114426981B (zh) * 2022-02-21 2022-11-29 吉林农业大学 非洲猪瘟病毒抗原蛋白重组表达载体、重组植物乳酸菌及其制备方法和应用
CN114438051B (zh) * 2022-04-07 2022-06-17 中国科学院天津工业生物技术研究所 磷酸吡哆醇合酶PdxJ突变体及其在制备维生素B6中的应用
CN114989266B (zh) * 2022-06-16 2024-02-13 华中农业大学 一种非洲猪瘟病毒pA104R蛋白免疫抑制相关氨基酸位点及其应用
CN115927460B (zh) * 2022-08-11 2023-08-29 绍兴君斐生物科技有限公司 抗非洲猪瘟病毒转基因的重组载体和猪成纤维细胞系及其构建方法和应用
CN115192599B (zh) * 2022-08-11 2024-01-16 中国农业科学院哈尔滨兽医研究所(中国动物卫生与流行病学中心哈尔滨分中心) 一种加米霉素在制备治疗非洲猪瘟的制剂中的应用
CN116023506B (zh) * 2022-08-31 2024-03-22 广东省农业科学院动物卫生研究所 Asfv非结构蛋白优势抗原表位融合蛋白及其试剂盒与应用
CN115806594B (zh) * 2022-12-08 2023-08-29 江苏农牧科技职业学院 用于检测非洲猪瘟病毒的重组抗原蛋白及其制备方法、检测试剂盒和应用
CN115806595B (zh) * 2022-12-08 2023-07-28 江苏农牧科技职业学院 非洲猪瘟病毒检测用重组抗原蛋白及其制备方法、检测试剂盒和应用
CN116492456B (zh) * 2023-03-31 2024-04-23 中国人民解放军军事科学院军事医学研究院 非洲猪瘟病毒d129l基因及其在制备复制缺陷型非洲猪瘟疫苗中的应用
CN116492455B (zh) * 2023-03-31 2024-04-23 中国人民解放军军事科学院军事医学研究院 非洲猪瘟病毒k421r基因及利用其制备的复制缺陷型非洲猪瘟疫苗
CN116284261B (zh) * 2023-04-04 2024-04-19 中国人民解放军军事科学院军事医学研究院 一种非洲猪瘟病毒结构蛋白组合物及其制备的疫苗
CN116589538B (zh) * 2023-04-10 2023-12-05 中国农业科学院兰州兽医研究所 七组分抗原非洲猪瘟亚单位疫苗
CN116903709A (zh) * 2023-07-03 2023-10-20 华中农业大学 一种非洲猪瘟病毒pK205R蛋白抗原表位肽及其单克隆抗体与应用
CN117106101A (zh) * 2023-10-20 2023-11-24 杭州百裕生物科技有限公司 质粒及asfv蛋白酶抑制剂筛选及药效评价的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2909462A (en) 1955-12-08 1959-10-20 Bristol Myers Co Acrylic acid polymer laxative compositions
US4708871A (en) 1983-03-08 1987-11-24 Commonwealth Serum Laboratories Commission Antigenically active amino acid sequences
WO2015091322A1 (en) 2013-12-18 2015-06-25 Boehringer Ingelheim Vetmedica Gmbh Cd2 deficient african swine fever virus as live attenuated or subsequently inactivated vaccine against african swine fever in mammals
GB201410971D0 (en) * 2014-06-19 2014-08-06 Pirbright Inst The Vaccine
CN104262484A (zh) 2014-10-17 2015-01-07 深圳出入境检验检疫局动植物检验检疫技术中心 一种抗非洲猪瘟病毒的特异性IgY抗体及制备方法和用途
WO2017096341A2 (en) * 2015-12-04 2017-06-08 The Texas A&M University System Adenovirus-vectored multivalent vaccine
CN110904127A (zh) 2018-09-18 2020-03-24 瓦赫宁恩研究基金会 非洲猪瘟病毒疫苗
WO2020102370A1 (en) 2018-11-15 2020-05-22 Kansas State University Research Foundation Immunogenic compositions for african swine fever virus
TW202102258A (zh) * 2019-03-27 2021-01-16 德商百靈佳殷格翰維美迪加股份有限公司 含有非洲豬瘟病毒肽及蛋白之免疫原組合物及疫苗以及其用途

Also Published As

Publication number Publication date
EP3946445A2 (en) 2022-02-09
US20200306360A1 (en) 2020-10-01
EA202192570A1 (ru) 2022-01-20
CA3130664A1 (en) 2020-10-01
AU2020247131A1 (en) 2021-11-11
US11628214B2 (en) 2023-04-18
WO2020193688A3 (en) 2021-04-08
JP2022525920A (ja) 2022-05-20
US20230277648A1 (en) 2023-09-07
CN113543801A (zh) 2021-10-22
TW202102258A (zh) 2021-01-16
WO2020193688A2 (en) 2020-10-01
KR20210145221A (ko) 2021-12-01

Similar Documents

Publication Publication Date Title
MX2021011687A (es) Composiciones inmunogenicas y vacunas que comprenden peptidos y proteinas del virus de la peste porcina africana y usos de las mismas.
EP3424524A3 (en) Cancer rna-vaccine
PH12019500068A1 (en) Novel adeno-associated virus capsid proteins
EA200901060A1 (ru) Новый способ и композиции
NZ730802A (en) Therapeutic hpv16 vaccines
MX2019008303A (es) Ácido ribonucleico modificado con nucleósidos para inducir una respuesta inmune contra el virus zika.
PE20190420A1 (es) Proteinas f de prefusion del virus respiratorio sincicial (vrs) solubles y estabilizadas
WO2016046234A3 (en) Recombinant phe-free proteins for use in the treatment of phenylketonuria
WO2016116905A9 (en) Cmv antigens and uses thereof
EA202090049A1 (ru) Поксвирусные векторы, кодирующие антигены вич, и способы их применения
MX2021015465A (es) Vacuna para fiebre porcina africana.
MX2022005252A (es) Composiciones de escherichia coli y metodos de las mismas.
WO2017214596A8 (en) Compositions and methods for preventing and treating zika virus infection
AR095482A1 (es) Virus del síndrome reproductivo y respiratorio porcino, composiciones, vacuna y métodos de uso
MX2022001028A (es) Vacuna de la fiebre porcina africana.
IN2012DN02692A (es)
MX2019003156A (es) Combinaciones de vacunas novedosas contra el virus del zika y construcciones de anticuerpos de adn para usar contra el virus del zika.
PH12017502380A1 (en) Prrsv minor protein-containing recombinant viral vectors and methods of making and use thereof
MX2022008073A (es) Anticuerpos dirigidos a los huesos.
ATE321853T1 (de) Humanische pellino-polypeptide
MX2018000023A (es) Particulas semejantes a virus recombinantes que utilizan la proteina gag del virus de inmunodeficiencia bovina.
MX2021014856A (es) Vacuna de tgf-beta.
PH12020551944A1 (en) Reverse peptide vaccine
MX2017008087A (es) Virus de la viruela porcina recombinante y vacunas.
EA201390811A1 (ru) Пептиды tomm34 и содержащие их вакцины