MX2021000209A - Metodos y productos para transfeccion de celulas. - Google Patents
Metodos y productos para transfeccion de celulas.Info
- Publication number
- MX2021000209A MX2021000209A MX2021000209A MX2021000209A MX2021000209A MX 2021000209 A MX2021000209 A MX 2021000209A MX 2021000209 A MX2021000209 A MX 2021000209A MX 2021000209 A MX2021000209 A MX 2021000209A MX 2021000209 A MX2021000209 A MX 2021000209A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- cells
- kits
- therapeutics
- nucleic acids
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 8
- 239000003814 drug Substances 0.000 abstract 3
- 102000039446 nucleic acids Human genes 0.000 abstract 3
- 108020004707 nucleic acids Proteins 0.000 abstract 3
- 150000007523 nucleic acids Chemical class 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 102000004169 proteins and genes Human genes 0.000 abstract 3
- 238000010362 genome editing Methods 0.000 abstract 2
- 230000001939 inductive effect Effects 0.000 abstract 2
- 230000008672 reprogramming Effects 0.000 abstract 2
- 125000002680 canonical nucleotide group Chemical group 0.000 abstract 1
- 239000013610 patient sample Substances 0.000 abstract 1
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Abstract
La presente invención se refiere en parte a ácidos nucleicos que codifican proteínas, ácidos nucleicos que contienen nucleótidos no canónicos, compuestos terapéuticos que comprenden ácidos nucleicos, métodos, kits y dispositivos para inducir la expresión de proteínas por parte de las células, métodos, kits y dispositivos para transfectar, editar los genes y reprogramar células, así como células, organismos y compuestos terapéuticos producidos utilizando estos métodos, kits y dispositivos. Se describen métodos para inducir la expresión de proteínas por parte de las células, así como para reprogramar y editar los genes de las células utilizando ARN. También se describen métodos para producir células a partir de muestras de pacientes, células producidas utilizando estos métodos y compuestos terapéuticos que comprenden células que utilizan estos métodos.
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