MX348776B - Produccion personalizada de productos biologicos y metodo para reprogramar celulas somaticas. - Google Patents

Produccion personalizada de productos biologicos y metodo para reprogramar celulas somaticas.

Info

Publication number
MX348776B
MX348776B MX2013007633A MX2013007633A MX348776B MX 348776 B MX348776 B MX 348776B MX 2013007633 A MX2013007633 A MX 2013007633A MX 2013007633 A MX2013007633 A MX 2013007633A MX 348776 B MX348776 B MX 348776B
Authority
MX
Mexico
Prior art keywords
treat
animal
nucleic acid
cells
somatic cells
Prior art date
Application number
MX2013007633A
Other languages
English (en)
Other versions
MX2013007633A (es
Inventor
Theresa D Deisher
Original Assignee
Avm Biotechnology Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avm Biotechnology Llc filed Critical Avm Biotechnology Llc
Publication of MX2013007633A publication Critical patent/MX2013007633A/es
Publication of MX348776B publication Critical patent/MX348776B/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
    • A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41—Glycosylation, sialylation, or fucosylation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/04—Immortalised cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2517/00—Cells related to new breeds of animals
    • C12N2517/04—Cells produced using nuclear transfer

Abstract

La presente invención se refiere a un in vitro para producir un polipéptido o proteína biológica terapéutica recombinante aislada para tratar una enfermedad que comprende transfectar una célula madre pluripotente producida sintéticamente (spPSC) con un ácido nucleico que codifica para dicho polipéptido o proteína biológica terapéutica recombinante, en condiciones en las que el polipéptido o proteína es expresada por dicha spPSC, y el polipéptido o proteína después es aislado de la spPSC, y la spPSC se produce a partir de una célula de un animal.
MX2013007633A 2011-01-03 2012-01-03 Produccion personalizada de productos biologicos y metodo para reprogramar celulas somaticas. MX348776B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161429409P 2011-01-03 2011-01-03
US201161431376P 2011-01-10 2011-01-10
PCT/US2012/020084 WO2012094321A1 (en) 2011-01-03 2012-01-03 Personalized production of biologics and method for reprogramming somatic cells

Publications (2)

Publication Number Publication Date
MX2013007633A MX2013007633A (es) 2015-07-14
MX348776B true MX348776B (es) 2017-06-28

Family

ID=45563510

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013007633A MX348776B (es) 2011-01-03 2012-01-03 Produccion personalizada de productos biologicos y metodo para reprogramar celulas somaticas.

Country Status (14)

Country Link
US (2) US9512200B2 (es)
EP (1) EP2661491A1 (es)
JP (2) JP6223829B2 (es)
KR (2) KR20140037036A (es)
CN (2) CN108017692A (es)
AU (1) AU2012204501B2 (es)
BR (1) BR112013018744B1 (es)
IL (1) IL227299B (es)
MX (1) MX348776B (es)
MY (1) MY161859A (es)
RU (1) RU2595390C2 (es)
SG (1) SG191836A1 (es)
WO (1) WO2012094321A1 (es)
ZA (1) ZA201305849B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
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US8916339B1 (en) 2013-10-31 2014-12-23 Vivex Biomedical, Inc. Spinal cord tissue dehydrated and micronized
WO2016088243A1 (ja) * 2014-12-05 2016-06-09 株式会社ニコン 判定装置、観察システム、観察方法、そのプログラム、細胞の製造方法、および細胞
US9402869B1 (en) 2015-03-27 2016-08-02 Vivex Biomedical, Inc. Treated neural tissue composition
US20180271908A1 (en) * 2015-05-01 2018-09-27 Cesca Therapeutics, Inc. Intramuscular administraton of autologous bone marrow for treatment
EP4026563A1 (en) * 2015-06-18 2022-07-13 Yeda Research and Development Co. Ltd Conditioning protocols and use of same for tissue regeneration
CN109563479A (zh) * 2016-05-25 2019-04-02 约翰霍普金斯大学 作为新型生物制剂递送平台的工程化的无核细胞和细胞外囊泡
CN110446638B (zh) 2017-03-24 2022-04-05 本田技研工业株式会社 发动机起动控制装置
US20190100729A1 (en) 2017-10-03 2019-04-04 Wallkill BioPharma, Inc. Treating diabetes with genetically modified beta cells
WO2019173756A1 (en) * 2018-03-09 2019-09-12 Avrobio, Inc. Compositions and methods for treating parkinson's disease
CN111269878B (zh) * 2020-01-19 2022-02-11 深圳市北科生物科技有限公司 一种人多能干细胞转化为扩展多能干细胞的专用培养基及其应用
CN112143697B (zh) * 2020-10-08 2021-08-06 宁波希诺赛生物科技有限公司 一种促进胚胎干细胞增殖和分化的方法
US20220154148A1 (en) * 2020-11-18 2022-05-19 Xingxin Wang Methods for engineering human pluripotent stem cells for diabetes therapy by co-transduction

Family Cites Families (18)

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US5591625A (en) 1993-11-24 1997-01-07 Case Western Reserve University Transduced mesenchymal stem cells
EP1064356A2 (en) 1998-03-23 2001-01-03 ZymoGenetics, Inc. Cardiac-derived stem cells
US6150459A (en) 1998-04-13 2000-11-21 Massachusetts Institute Of Technology Comb polymers for regulating cell surface interactions
WO2004009618A2 (en) 2002-07-18 2004-01-29 Crucell Holland B.V. Recombinant production of mixtures of antibodies
JP4817514B2 (ja) * 2001-03-09 2011-11-16 協和発酵キリン株式会社 新規動物細胞用ベクターおよびその使用
WO2003101202A1 (en) 2002-05-31 2003-12-11 Osiris Therapeutics, Inc. Intraperitoneal delivery of genetically engineered mesenchymal stem cells
FR2878860A1 (fr) * 2004-12-08 2006-06-09 Vivalis Sa Lignees de cellules souches humaines derivees de cellules es et utilisations pour la production de vaccins et de proteines recombinantes
US8278104B2 (en) * 2005-12-13 2012-10-02 Kyoto University Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2
CN101432425A (zh) * 2006-01-04 2009-05-13 环球健康有限公司 通过转染由成体干细胞产生胰岛素分泌细胞的方法
WO2008148105A1 (en) * 2007-05-25 2008-12-04 Medistem Laboratories, Inc. Endometrial stem cells and methods of making and using same
CA2660123C (en) * 2007-10-31 2017-05-09 Kyoto University Nuclear reprogramming method
WO2009091543A1 (en) * 2008-01-14 2009-07-23 Lindner Scott E An efficient orip/ebna-1 plasmid vector
US20090241206A1 (en) 2008-03-04 2009-09-24 University Of Iowa Research Foundation Methods for cloning ferrets and transgenic ferret models for diseases
WO2009151207A1 (ko) * 2008-06-13 2009-12-17 한쎌 주식회사 인간 간성장인자를 발현하는 중간엽 줄기세포, 그의 제조방법 및 그의 간질환 치료제로서의 용도
US20110263015A1 (en) * 2008-08-20 2011-10-27 Virxsys Corporation Compositions and methods for generation of pluripotent stem cells
BRPI1006992B1 (pt) * 2009-01-26 2018-12-18 Pasteuria Bioscience Inc método para controle de nematoides e composição nematicida
JP6215533B2 (ja) * 2009-04-09 2017-10-18 サンガモ セラピューティクス， インコーポレイテッド 幹細胞への標的組込み
JP2010268789A (ja) * 2009-04-24 2010-12-02 Kumamoto Univ 細胞医薬の製造方法

Also Published As

Publication number Publication date
MX2013007633A (es) 2015-07-14
US9512200B2 (en) 2016-12-06
NZ613888A (en) 2015-07-31
US10030230B2 (en) 2018-07-24
US20170081641A1 (en) 2017-03-23
JP6223829B2 (ja) 2017-11-01
BR112013018744B1 (pt) 2022-03-29
CN108017692A (zh) 2018-05-11
ZA201305849B (en) 2014-10-29
RU2595390C2 (ru) 2016-08-27
RU2013136357A (ru) 2015-02-10
AU2012204501A1 (en) 2013-08-22
JP6373459B2 (ja) 2018-08-15
AU2012204501B2 (en) 2016-05-19
CN103403152A (zh) 2013-11-20
JP2018007660A (ja) 2018-01-18
KR20170120726A (ko) 2017-10-31
WO2012094321A4 (en) 2012-09-20
US20120171722A1 (en) 2012-07-05
SG191836A1 (en) 2013-08-30
IL227299B (en) 2020-06-30
JP2014501118A (ja) 2014-01-20
KR20140037036A (ko) 2014-03-26
WO2012094321A1 (en) 2012-07-12
IL227299A0 (en) 2013-09-30
BR112013018744A2 (pt) 2016-09-20
EP2661491A1 (en) 2013-11-13
MY161859A (en) 2017-05-15

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