MEP2208A - Postupak za pripremanje citaloprama - Google Patents

Postupak za pripremanje citaloprama

Info

Publication number
MEP2208A
MEP2208A MEP-22/08A MEP2208A MEP2208A ME P2208 A MEP2208 A ME P2208A ME P2208 A MEP2208 A ME P2208A ME P2208 A MEP2208 A ME P2208A
Authority
ME
Montenegro
Prior art keywords
formula
citalopram
compound
preparation
halo
Prior art date
Application number
MEP-22/08A
Other languages
Bosnian (bs)
English (en)
Inventor
Hans Petersen
Haleh Ahmadian
Robert J M Dancer
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of MEP2208A publication Critical patent/MEP2208A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
MEP-22/08A 2000-08-18 2001-08-14 Postupak za pripremanje citaloprama MEP2208A (xx)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200001231 2000-08-18
PCT/DK2001/000542 WO2002016342A1 (en) 2000-08-18 2001-08-14 Method for the preparation of citalopram

Publications (1)

Publication Number Publication Date
MEP2208A true MEP2208A (xx) 2010-02-10

Family

ID=8159660

Family Applications (2)

Application Number Title Priority Date Filing Date
MEP-22/08A MEP2208A (xx) 2000-08-18 2001-08-14 Postupak za pripremanje citaloprama
MEP-23/08A MEP2308A (xx) 2000-08-18 2001-08-14 Postupak za pripremanje citaloprama

Family Applications After (1)

Application Number Title Priority Date Filing Date
MEP-23/08A MEP2308A (xx) 2000-08-18 2001-08-14 Postupak za pripremanje citaloprama

Country Status (41)

Country Link
US (2) US6426422B1 (no)
EP (2) EP1309582B1 (no)
JP (2) JP2004506730A (no)
KR (2) KR100887206B1 (no)
CN (3) CN1222517C (no)
AR (3) AR029597A1 (no)
AT (4) ATE281448T1 (no)
AU (6) AU7960901A (no)
BE (2) BE1013443A6 (no)
BG (2) BG65964B1 (no)
CA (2) CA2354877C (no)
CH (2) CH691968A5 (no)
CL (2) CL2008002412A1 (no)
CZ (2) CZ294746B6 (no)
DE (4) DE60106932T2 (no)
DK (4) DK200101219A (no)
EA (2) EA005946B1 (no)
ES (4) ES2228920T3 (no)
FI (2) FI20011621A (no)
FR (2) FR2813077B1 (no)
GB (2) GB2365865B (no)
GR (1) GR1004074B (no)
HK (3) HK1044538B (no)
HR (2) HRP20030064A2 (no)
HU (2) HUP0103291A3 (no)
IE (2) IES20010760A2 (no)
IL (2) IL144816A (no)
IS (2) IS2121B (no)
ME (2) MEP2208A (no)
MX (2) MXPA03001329A (no)
NL (2) NL1018776C1 (no)
NO (2) NO326570B1 (no)
NZ (2) NZ523877A (no)
PL (2) PL359825A1 (no)
PT (2) PT1309581E (no)
RS (2) RS50287B (no)
SI (2) SI1309582T1 (no)
SK (2) SK287236B6 (no)
UA (2) UA72340C2 (no)
WO (2) WO2002016342A1 (no)
ZA (1) ZA200106683B (no)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
EP1173431B2 (en) 1999-04-14 2009-08-26 H. Lundbeck A/S Method for the preparation of citalopram
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
PT1228056E (pt) 1999-10-25 2005-02-28 Lundbeck & Co As H Metodo de preparacao de citaloprame
AR026063A1 (es) 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
AU778751B2 (en) 1999-12-28 2004-12-16 H. Lundbeck A/S Method for the preparation of citalopram
DK1246813T3 (da) 1999-12-30 2004-03-01 Lundbeck & Co As H Fremgangsmåde til fremstilling af Citalopram
TR200201783T2 (tr) * 2000-01-14 2002-12-23 H. Lundbeck A/S 5-Siyanofatalid hazırlamak için yöntem
NL1017417C1 (nl) 2000-03-03 2001-03-16 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
IES20010206A2 (en) 2000-03-13 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
JP2003527385A (ja) * 2000-03-13 2003-09-16 ハー・ルンドベック・アクチエゼルスカベット ５−置換された１−（４−フルオロフェニル）−１，３−ジヒドロイソベンゾフランの段階的アルキル化法
IL151490A0 (en) 2000-03-13 2003-04-10 Lundbeck & Co As H Method for the preparation of citalopram
TR200400611T4 (tr) 2000-03-14 2004-04-21 H.Lundbeck A/S Sitalopramın preparasyon metodu
CZ20023406A3 (cs) * 2000-03-16 2003-01-15 H. Lundbeck A/S Způsob výroby 5-kyano-1-(4-fluorfenyl)-1,3-dihydroisobenzofuranu
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
CA2354877C (en) 2000-08-18 2006-05-02 H. Lundbeck A/S Method for the preparation of citalopram
EP1462447A3 (en) 2000-12-22 2004-11-17 H. Lundbeck A/S Method for the preparation of pure citalopram
WO2003057132A2 (en) * 2002-01-07 2003-07-17 Sun Pharmaceutical Industries Limited Process for the preparation of 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)- 1,3-dihydro-5-isobenzofuran carbonitrile
PE20040991A1 (es) * 2002-08-12 2004-12-27 Lundbeck & Co As H Separacion de intermediarios para la preparacion de escitalopram
AU2003223105A1 (en) * 2003-03-24 2004-10-18 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
US20050143350A1 (en) * 2003-11-19 2005-06-30 Seed John C. Combination drug therapy to treat obesity
CN100569765C (zh) 2003-12-19 2009-12-16 杭州民生药业集团有限公司 西酞普兰中间体晶体碱
US9339500B2 (en) * 2008-03-04 2016-05-17 Intra-Cellular Therapies, Inc. Methods of treating vasomotor symptoms
US20100087664A1 (en) * 2008-10-07 2010-04-08 Ravindra Vedantham Preparation of citalopram and salts thereof
JP6222973B2 (ja) * 2013-04-19 2017-11-01 日本テルペン化学株式会社 ジベンジルトリチオカーボネート誘導体
CN103936702A (zh) * 2014-05-07 2014-07-23 成都诺维尔生物医药有限公司 艾司西酞普兰杂质j的合成方法

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143702A (no) 1965-03-18
GB1526331A (en) * 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8419963D0 (en) 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
GB8814057D0 (en) 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
DE3926765A1 (de) 1989-08-12 1991-02-14 Hoechst Ag Verfahren zur verminderung von primaerem und sekundaerem amin in einem tertiaeren amin
US5296507A (en) 1990-09-06 1994-03-22 H.Lundbeck A/S Treatment of cerbrovascular disorders
DK213290D0 (da) 1990-09-06 1990-09-06 Lundbeck & Co As H Treatment of cerebrovascular disorders
DE19626659A1 (de) 1996-07-03 1998-01-08 Basf Ag Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de) 1996-07-10 1998-01-15 Basf Ag Verfahren zur Herstellung von Phthaliden
ZA9711376B (en) 1996-12-20 1998-07-21 Lundbeck & Co As H Indole or dihydroindole derivatives
HU228744B1 (en) * 1997-07-08 2013-05-28 Lundbeck & Co As H Method for preparation of citalopram and intermediates used for them
UA62985C2 (en) 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
EP1042310B1 (en) 1997-11-11 2002-07-31 H. Lundbeck A/S Method for the preparation of citalopram
CN1129592C (zh) 1998-10-20 2003-12-03 H·隆德贝克有限公司 制备西酞普兰的方法
ES2195644T3 (es) 1998-12-23 2003-12-01 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida.
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
EP1173431B2 (en) 1999-04-14 2009-08-26 H. Lundbeck A/S Method for the preparation of citalopram
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991579A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
AU742554B2 (en) 1999-10-25 2002-01-03 H. Lundbeck A/S Method for the preparation of citalopram
US6310222B1 (en) 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
NL1017415C1 (nl) 2000-02-24 2001-05-18 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
IES20010143A2 (en) 2000-02-24 2001-07-25 Lundbeck & Co As H Method for the preparation of citalopram
GB0005477D0 (en) * 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
CA2354877C (en) 2000-08-18 2006-05-02 H. Lundbeck A/S Method for the preparation of citalopram
EP1462447A3 (en) 2000-12-22 2004-11-17 H. Lundbeck A/S Method for the preparation of pure citalopram
AU3920201A (en) 2000-12-28 2001-07-09 H. Lundbeck A/S Process for the preparation of pure citalopram

Also Published As

Publication number Publication date
DE60106932T2 (de) 2005-11-03
ES2170735A1 (es) 2002-08-01
GB0119733D0 (en) 2001-10-03
IES20010760A2 (en) 2002-02-20
KR20030022378A (ko) 2003-03-15
NO20013943D0 (no) 2001-08-14
NO20013943L (no) 2002-02-19
UA71676C2 (en) 2004-12-15
MEP2308A (xx) 2010-02-10
RS50258B (sr) 2009-07-15
NO326570B1 (no) 2009-01-12
ATE281447T1 (de) 2004-11-15
IL144816A (en) 2005-09-25
ES2170735B2 (es) 2003-09-16
FI20011621A0 (fi) 2001-08-09
MXPA03001329A (es) 2003-06-06
IS6047A (is) 2001-10-20
PL359825A1 (en) 2004-09-06
NO20013942D0 (no) 2001-08-14
AU2001279609B2 (en) 2007-09-06
DE10140029A1 (de) 2002-05-02
NZ523877A (en) 2004-08-27
NO20013942L (no) 2002-02-19
DE10140028A1 (de) 2002-04-18
US20020025982A1 (en) 2002-02-28
BE1013444A6 (fr) 2002-01-15
ES2230347T3 (es) 2005-05-01
SI1309581T1 (en) 2005-04-30
CN1515564A (zh) 2004-07-28
BG65965B1 (bg) 2010-07-30
FI20011622A0 (fi) 2001-08-09
PL359969A1 (en) 2004-09-06
AT5026U1 (de) 2002-02-25
NL1018776C1 (nl) 2001-10-24
UA72340C2 (uk) 2005-02-15
KR100887206B1 (ko) 2009-03-06
AT4946U1 (de) 2002-01-25
EP1309582A1 (en) 2003-05-14
HK1047086B (zh) 2005-04-22
CA2354880A1 (en) 2002-01-22
CZ20012958A3 (cs) 2002-04-17
HRP20030065A2 (en) 2005-02-28
WO2002016341A1 (en) 2002-02-28
HUP0103291A3 (en) 2003-02-28
CA2354880C (en) 2003-06-03
AU2001279608B2 (en) 2006-10-05
DK1309582T3 (da) 2005-03-14
MXPA03000913A (es) 2003-06-24
DK1309581T3 (da) 2005-03-14
IS2120B (is) 2006-06-15
FR2813077A1 (fr) 2002-02-22
NO326772B1 (no) 2009-02-16
SK3222003A3 (en) 2003-08-05
GB2365865B (en) 2002-07-17
GB2362647A (en) 2001-11-28
KR100887207B1 (ko) 2009-03-06
HK1068069A1 (en) 2005-04-22
AR066694A2 (es) 2009-09-09
IES20010761A2 (en) 2002-02-20
JP2004506730A (ja) 2004-03-04
EP1309581B1 (en) 2004-11-03
CZ295863B6 (cs) 2005-11-16
BG65964B1 (bg) 2010-07-30
GR20010100398A (el) 2002-05-24
EA200300279A1 (ru) 2003-08-28
PT1309581E (pt) 2005-03-31
ES2228920T3 (es) 2005-04-16
EA005946B1 (ru) 2005-08-25
ES2170734A1 (es) 2002-08-01
GR1004074B (el) 2002-11-26
BG107583A (bg) 2004-01-30
IL144816A0 (en) 2002-06-30
AU2001100278B4 (en) 2001-11-29
YU11503A (sh) 2006-05-25
DK200101219A (da) 2002-02-19
JP2004506729A (ja) 2004-03-04
FR2813077B1 (fr) 2004-08-20
HK1044538B (zh) 2006-07-07
PT1309582E (pt) 2005-03-31
NZ523853A (en) 2004-07-30
US6426422B1 (en) 2002-07-30
BG107584A (bg) 2004-01-30
ES2170734B2 (es) 2003-09-16
AR029598A1 (es) 2003-07-10
CN1239490C (zh) 2006-02-01
SK3202003A3 (en) 2003-08-05
CZ20012959A3 (cs) 2002-04-17
RS50287B (sr) 2009-09-08
YU6903A (sh) 2006-05-25
CN1222517C (zh) 2005-10-12
DE60106932D1 (de) 2004-12-09
KR20030022385A (ko) 2003-03-15
CH691969A5 (de) 2001-12-14
EP1309581A1 (en) 2003-05-14
HU0103291D0 (en) 2001-10-28
CA2354877C (en) 2006-05-02
EP1309582B1 (en) 2004-11-03
EA005811B1 (ru) 2005-06-30
HUP0103295A2 (hu) 2002-05-29
CZ294746B6 (cs) 2005-03-16
CL2008002673A1 (es) 2009-01-02
DE60106933D1 (de) 2004-12-09
GB2362647B (en) 2002-09-18
CL2008002412A1 (es) 2009-01-02
ATE281448T1 (de) 2004-11-15
AU2001100271A4 (en) 2001-09-13
DE60106933T2 (de) 2005-12-01
CN1159307C (zh) 2004-07-28
CH691968A5 (de) 2001-12-14
CN1339436A (zh) 2002-03-13
FR2813078B1 (fr) 2004-04-02
AR029597A1 (es) 2003-07-10
IL144817A0 (en) 2002-06-30
FI20011621A (fi) 2002-02-19
IS6048A (is) 2001-10-19
CN1339435A (zh) 2002-03-13
AU2001100271B4 (en) 2001-11-29
AU2001100278A4 (en) 2001-09-13
SI1309582T1 (en) 2005-06-30
HUP0103291A2 (hu) 2002-05-29
SK287236B6 (sk) 2010-04-07
SK287008B6 (sk) 2009-09-07
FR2813078A1 (fr) 2002-02-22
BE1013443A6 (fr) 2002-01-15
DK200101216A (da) 2002-02-19
FI20011622A (fi) 2002-02-19
HUP0103295A3 (en) 2005-01-28
HK1047086A1 (en) 2003-02-07
AU7960801A (en) 2002-03-04
US6509483B2 (en) 2003-01-21
HRP20030064A2 (en) 2005-02-28
AU7960901A (en) 2002-03-04
EA200300277A1 (ru) 2003-08-28
NL1018775C1 (nl) 2001-10-24
US20020026062A1 (en) 2002-02-28
GB0119734D0 (en) 2001-10-03
ZA200106683B (en) 2002-08-05
CA2354877A1 (en) 2002-02-18
IS2121B (is) 2006-06-15
HK1044538A1 (en) 2002-10-25
GB2365865A (en) 2002-02-27
WO2002016342A1 (en) 2002-02-28

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