ME02965B - Kombinacije antagonista muskarinskog receptora i agonista вета - 2 adrenoreceptora - Google Patents

Kombinacije antagonista muskarinskog receptora i agonista вета - 2 adrenoreceptora

Info

Publication number
ME02965B
ME02965B MEP-2018-45A MEP4518A ME02965B ME 02965 B ME02965 B ME 02965B ME P4518 A MEP4518 A ME P4518A ME 02965 B ME02965 B ME 02965B
Authority
ME
Montenegro
Prior art keywords
adrenoreceptors
vet
agonists
combinations
receptor antagonists
Prior art date
Application number
MEP-2018-45A
Other languages
German (de)
English (en)
French (fr)
Inventor
Darrell Baker
Mark Bruce
Glenn Crater
Brian Noga
Marian Thomas
Patrick Wire
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41573013&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ME02965(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ME02965B publication Critical patent/ME02965B/me

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D75/36Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet or blank being recessed and the other formed of relatively stiff flat sheet material, e.g. blister packages, the recess or recesses being preformed
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/203Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26Acyclic or carbocyclic radicals, substituted by hetero rings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Otolaryngology (AREA)
  • Mechanical Engineering (AREA)
  • Composite Materials (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
MEP-2018-45A 2009-12-01 2010-11-29 Kombinacije antagonista muskarinskog receptora i agonista вета - 2 adrenoreceptora ME02965B (me)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0921075.8A GB0921075D0 (en) 2009-12-01 2009-12-01 Novel combination of the therapeutic agents
PCT/EP2010/068429 WO2011067212A1 (en) 2009-12-01 2010-11-29 Combinations of a muscarinic receptor antagonist and a beta-2 adrenoreceptor agonist
EP10781527.6A EP2506844B1 (en) 2009-12-01 2010-11-29 Combinations of a muscarinic receptor antagonist and a beta-2 adrenoreceptor agonist

Publications (1)

Publication Number Publication Date
ME02965B true ME02965B (me) 2018-07-20

Family

ID=41573013

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-2018-45A ME02965B (me) 2009-12-01 2010-11-29 Kombinacije antagonista muskarinskog receptora i agonista вета - 2 adrenoreceptora

Country Status (42)

Country Link
US (8) US20120309725A1 (me)
EP (3) EP2506844B1 (me)
JP (1) JP5816631B2 (me)
KR (2) KR101742140B1 (me)
CN (2) CN102724974A (me)
AU (6) AU2010326798B2 (me)
BR (1) BR112012012925A2 (me)
CA (1) CA2781487C (me)
CL (1) CL2012001432A1 (me)
CO (1) CO6541613A2 (me)
CR (1) CR20120265A (me)
CY (2) CY1120058T1 (me)
DK (2) DK2506844T3 (me)
DO (1) DOP2012000148A (me)
EA (1) EA023839B1 (me)
ES (2) ES2979060T3 (me)
FI (2) FI3335707T3 (me)
FR (1) FR18C1022I2 (me)
GB (1) GB0921075D0 (me)
HR (2) HRP20180312T1 (me)
HU (3) HUE036216T2 (me)
IL (1) IL219893A (me)
LT (3) LT3335707T (me)
LU (1) LUC00077I2 (me)
MA (1) MA33853B1 (me)
ME (1) ME02965B (me)
MX (1) MX351290B (me)
MY (2) MY207466A (me)
NO (2) NO2506844T3 (me)
NZ (1) NZ600026A (me)
PE (2) PE20170915A1 (me)
PH (1) PH12012501083A1 (me)
PL (2) PL3335707T3 (me)
PT (2) PT3335707T (me)
RS (2) RS65494B1 (me)
SG (2) SG10201407864UA (me)
SI (2) SI3335707T1 (me)
SM (2) SMT201800129T1 (me)
TR (1) TR201802921T4 (me)
UA (1) UA106775C2 (me)
WO (1) WO2011067212A1 (me)
ZA (1) ZA201203890B (me)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR050902A1 (es) 2004-04-27 2006-12-06 Glaxo Group Ltd Compuesto de quinuclidina, composicion farmaceutica que lo comprende y su usopara preparar dicha composicion
PL3578169T3 (pl) 2009-02-26 2024-09-02 Glaxo Group Limited Preparaty farmaceutyczne zawierające 4-{(1r)-2-[(6-{2-[(2,6-dichlorobenzylo)oksy]etoksy}heksylo)amino]-1-hydroksyetylo}-2-(hydroksymetylo)fenol
GB0921075D0 (en) 2009-12-01 2010-01-13 Glaxo Group Ltd Novel combination of the therapeutic agents
AU2011298315B2 (en) * 2010-08-31 2014-08-28 Glaxo Group Limited Dry powder inhalation drug products exhibiting moisture control properties and methods of administering the same
BR112013031570A2 (pt) * 2011-06-08 2017-03-21 Glaxo Group Ltd inalador de pó seco.
WO2012168161A1 (en) * 2011-06-08 2012-12-13 Glaxo Group Limited Combination comprising umeclidinium and a corticosteroid
BR112014025518B1 (pt) 2012-04-13 2022-05-24 Glaxosmithkline Intellectual Property Development Limited Partículas agregadas de umeclidinium, vilanterol e fluticasona, composição em pó, inalador, processo para a preparação de partículas agregadas, e, uso de estearato de magnésio em partículas agregadas
GB201222679D0 (en) 2012-12-17 2013-01-30 Glaxo Group Ltd Pharmaceutical combination products
GB201305825D0 (en) 2013-03-28 2013-05-15 Vectura Ltd New use
US10987363B2 (en) * 2014-05-28 2021-04-27 Glaxosmithkline Intellectual Property Development Limited Fluticasone furoate in the treatment of COPD
TR201407010A2 (tr) 2014-06-16 2015-12-21 Arven Ilac Sanayi Ve Ticaret Anonim Sirketi Vilanterol formülasyonları.
EP2957552B1 (en) 2014-06-16 2020-01-22 Arven Ilac Sanayi Ve Ticaret A.S. Vilanterol formulations
CA2952760A1 (en) 2014-06-18 2015-12-23 Cipla Limited Pharmaceutical composition comprising a beta-2-agonist and anticholinergic agent
EP3880169B1 (en) * 2018-11-12 2025-07-23 Kindeva Drug Delivery L.P. Umeclidinium and vilanterol formulation and inhaler
CN111840256A (zh) * 2019-04-29 2020-10-30 上海谷森医药有限公司 一种雾化吸入剂及其制备方法
WO2020237151A1 (en) 2019-05-23 2020-11-26 Huang Cai Gu Inhalable formulation of a solution containing vilanterol trifenatate and umeclidinium bromide
WO2021009573A1 (en) * 2019-07-12 2021-01-21 Kindeva Drug Delivery L.P. Aerosol formulation, canister and inhaler containing the formulation, and method of use
CN115768404B (zh) * 2020-06-09 2024-11-08 广州谷森制药有限公司 含乌美溴铵和三苯乙酸维兰特罗的药物制剂
EP4706711A2 (en) 2021-08-13 2026-03-11 Norton (Waterford) Limited Dry powder medicament inhaler
EP4221792B1 (en) 2021-09-29 2025-05-14 Norton (Waterford) Limited Dry powder medicament inhaler

Family Cites Families (182)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB124009A (en) 1918-01-12 1919-03-12 Walter Edward Kimber Improvements in and connected with the Manufacture of Tools for Turning, Planing, Boring and similar purposes.
GB124010A (en) 1919-01-10 1919-03-20 Rene Emile Dior Improved Process for the Manufacture of Synthetic Resins.
GB1242211A (en) 1967-08-08 1971-08-11 Fisons Pharmaceuticals Ltd Pharmaceutical composition
GB1381872A (en) 1971-06-22 1975-01-29 Fisons Ltd Pharmaceutical compositions for inhalation
FR2182892B1 (me) 1972-03-25 1976-11-05 Degussa
CY1308A (en) 1979-12-06 1985-12-06 Glaxo Group Ltd Device for dispensing medicaments
ATE23272T1 (de) 1981-07-08 1986-11-15 Draco Ab Pulverinhalator.
ES286422Y (es) 1982-10-08 1986-09-16 Glaxo Group Limited Dispositivo para administrar medicamentos a pacientes
US4778054A (en) 1982-10-08 1988-10-18 Glaxo Group Limited Pack for administering medicaments to patients
GB2169265B (en) 1982-10-08 1987-08-12 Glaxo Group Ltd Pack for medicament
PT83094B (pt) 1985-07-30 1993-07-30 Glaxo Group Ltd Dispositivos proprios para a administracao de medicamentos a pacientes
GB8530365D0 (en) 1985-12-10 1986-01-22 Univ Bath Manufacture of moulded products
IT1204826B (it) 1986-03-04 1989-03-10 Chiesi Farma Spa Composizioni farmaceutiche per inalazione
CA1329526C (en) 1987-08-20 1994-05-17 Hiroshi Ikura Powdery medicine applicator device
US4994276A (en) 1988-09-19 1991-02-19 Edward Mendell Co., Inc. Directly compressible sustained release excipient
GB8820353D0 (en) 1988-08-26 1988-09-28 Staniforth J N Controlled release tablet
US5135757A (en) 1988-09-19 1992-08-04 Edward Mendell Co., Inc. Compressible sustained release solid dosage forms
US5376386A (en) 1990-01-24 1994-12-27 British Technology Group Limited Aerosol carriers
GB9004781D0 (en) 1990-03-02 1990-04-25 Glaxo Group Ltd Device
US6536427B2 (en) 1990-03-02 2003-03-25 Glaxo Group Limited Inhalation device
SK280968B6 (sk) 1990-03-02 2000-10-09 Glaxo Group Limited Balenie medikamentu na použite v inhalačnom prístroji
UA26230A (uk) 1990-03-02 1999-07-19 Глексо Груп Лімітед Іhгалятор для спільhого використаhhя з лікувальhим блоком і лікувальhий блок
FR2660634B1 (fr) 1990-04-06 1992-10-16 Airsec Ind Sa Conditionnement pour produits necessitant l'usage d'un agent deshydratant.
JPH0471560A (ja) 1990-07-10 1992-03-06 Mect Corp 包装体
US5145684A (en) 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
DE4140689B4 (de) 1991-12-10 2007-11-22 Boehringer Ingelheim Kg Inhalationspulver und Verfahren zu ihrer Herstellung
DE69330672T2 (de) 1992-06-12 2002-06-27 Teijin Ltd., Osaka Pharmazeutische zubereitung zur anwendung in den atemwegen
WO1993025198A1 (fr) 1992-06-12 1993-12-23 Teijin Limited Poudre ultra-fine pour inhalation et production de cette poudre
GB2269992A (en) 1992-08-14 1994-03-02 Rh Ne Poulenc Rorer Limited Powder inhalation formulations
ATE153299T1 (de) 1992-09-09 1997-06-15 Fisons Plc Pharmazeutisches verpacken
SE9203743D0 (sv) 1992-12-11 1992-12-11 Astra Ab Efficient use
PL173090B1 (pl) 1992-12-18 1998-01-30 Schering Corp Inhalator do sproszkowanych lekarstw
US5441060A (en) 1993-02-08 1995-08-15 Duke University Dry powder delivery system
AU679511B2 (en) 1993-03-17 1997-07-03 Minnesota Mining And Manufacturing Company Aerosol formulation containing an ester-, amide-, or mercaptoester-derived dispersing aid
US5730785A (en) 1993-04-01 1998-03-24 Multisorb Technologies, Inc. Desiccant canister for desiccants and other particulate material
IS1796B (is) 1993-06-24 2001-12-31 Ab Astra Fjölpeptíð lyfjablanda til innöndunar sem einnig inniheldur eykjaefnasamband
US5506203C1 (en) 1993-06-24 2001-02-06 Astra Ab Systemic administration of a therapeutic preparation
DE4323636A1 (de) 1993-07-15 1995-01-19 Hoechst Ag Arzneistoffzubereitungen aus umhüllten, schwerstwasserlöslichen Arzneistoffen für Inhalationsarzneiformen und Verfahren zu ihrer Herstellung
GB9322014D0 (en) 1993-10-26 1993-12-15 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
US5503662A (en) 1994-03-29 1996-04-02 Multiform Desiccants, Inc. Canister with porous plastic ends
FI95441C (fi) 1994-05-31 1996-02-12 Leiras Oy Inhalointilaitteen lääkeainekammio
US6156231A (en) 1994-09-08 2000-12-05 Multisorb Technologies, Inc. Oxygen absorbing composition with cover layer
US5641425A (en) 1994-09-08 1997-06-24 Multiform Desiccants, Inc. Oxygen absorbing composition
SA95160463B1 (ar) 1994-12-22 2005-10-04 استرا أكتيبولاج مساحيق للاستنشاق
GB9501841D0 (en) 1995-01-31 1995-03-22 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
US6279736B1 (en) 1995-04-19 2001-08-28 Capitol Specialty Plastics, Inc. Barrier pack having an absorbing agent applied to the interior of the pack
CA2218559C (en) 1995-04-19 2006-08-15 Capitol Vial, Inc. Desiccant material included in a closed container
GB9515182D0 (en) 1995-07-24 1995-09-20 Co Ordinated Drug Dev Improvements in and relating to powders for use in dry powder inhalers
GB9700226D0 (en) 1997-01-08 1997-02-26 Glaxo Group Ltd Inhalation device
US6103141A (en) 1997-01-23 2000-08-15 Multisorb Technologies, Inc. Desiccant deposit
US6126919A (en) 1997-02-07 2000-10-03 3M Innovative Properties Company Biocompatible compounds for pharmaceutical drug delivery systems
AU6700998A (en) 1997-03-14 1998-09-29 University Of Houston, The Methods for making fluorinated surface modifying agents, methods of using same and products made using same
US5985415A (en) 1997-11-17 1999-11-16 Reconnx, Inc. Finger joint architecture for wood products, and method and apparatus for formation thereof
US6086376A (en) 1998-01-30 2000-07-11 Rtp Pharma Inc. Dry aerosol suspension of phospholipid-stabilized drug microparticles in a hydrofluoroalkane propellant
PT1291322E (pt) 1998-02-05 2005-07-29 Du Pont Processo para aumentar o teor em humidade numa materia desidratada
JP2002512183A (ja) 1998-04-18 2002-04-23 グラクソ グループ リミテッド 医薬用エアゾール製剤
US7521068B2 (en) 1998-11-12 2009-04-21 Elan Pharma International Ltd. Dry powder aerosols of nanoparticulate drugs
CA2347856C (en) 1998-11-13 2009-02-17 Jagotec Ag Dry powder for inhalation
US20070212422A1 (en) 1999-11-10 2007-09-13 Manfred Keller Dry powder for inhalation
GB9827145D0 (en) 1998-12-09 1999-02-03 Co Ordinated Drug Dev Improvements in or relating to powders
US6390291B1 (en) 1998-12-18 2002-05-21 Smithkline Beecham Corporation Method and package for storing a pressurized container containing a drug
US6119853A (en) 1998-12-18 2000-09-19 Glaxo Wellcome Inc. Method and package for storing a pressurized container containing a drug
US6352152B1 (en) 1998-12-18 2002-03-05 Smithkline Beecham Corporation Method and package for storing a pressurized container containing a drug
US6315112B1 (en) 1998-12-18 2001-11-13 Smithkline Beecham Corporation Method and package for storing a pressurized container containing a drug
WO2001097888A2 (en) 2000-06-22 2001-12-27 Glaxo Group Limited Method and package for storing a pressurized container containing a drug
IT1309592B1 (it) 1999-03-05 2002-01-24 Chiesi Farma Spa Particelle veicolo modificate da utilizzarsi nella preparazione diformulazioni farmaceutiche sotto forma di polimeri per inalazione e
PL196951B1 (pl) 1999-03-05 2008-02-29 Chiesi Farma Spa Proszek do stosowania w inhalatorze suchego proszku, cząsteczki nośnika i sposób wytwarzania nośnika
USD440874S1 (en) 1999-07-29 2001-04-24 The Gillette Company Container
HUP0203626A2 (en) 1999-10-11 2003-02-28 Ml Lab Plc Medicament delivery device with moisture resistant coating
DE19957802A1 (de) 1999-12-01 2001-06-07 Trw Repa Gmbh Gurtaufrollersystem
GB0008660D0 (en) 2000-04-07 2000-05-31 Arakis Ltd The treatment of respiratory diseases
AU2001252350A1 (en) 2000-04-13 2001-10-30 Innovata Biomed Limited Medicaments for treating respiratory disorders comprising formoterol and fluticasone
PE20011227A1 (es) 2000-04-17 2002-01-07 Chiesi Farma Spa Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros
EP1353854A2 (en) 2000-05-15 2003-10-22 Glaxo Group Limited Aerosol mdi overcap containing desiccant
GB0015043D0 (en) 2000-06-21 2000-08-09 Glaxo Group Ltd Medicament dispenser
PT1305329E (pt) 2000-08-05 2007-12-24 Glaxo Group Ltd Éster s-fluorometílico do ácido 6.alfa.,9.alfa.-difluoro- 17.alfa.-(2-furanilcarboxil)oxi-11.beta.-hidroxi-16.alfa.-metil- 3-oxo-androsta-1,4-dieno-17-carbotióico como um agente antiinflamatório
GB0019172D0 (en) 2000-08-05 2000-09-27 Glaxo Group Ltd Novel compounds
US6759398B2 (en) 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
DE10056855A1 (de) 2000-11-16 2002-05-29 Lohmann Therapie Syst Lts Verbundlaminat mit Sauerstoff und Feuchtigkeit absorbierender Schicht und Verfahren zu seiner Herstellung
ES2587135T3 (es) 2000-11-30 2016-10-20 Vectura Limited Procedimiento de fabricación de partículas para su uso en una composición farmacéutica
EP1337239B2 (en) 2000-11-30 2015-11-25 Vectura Limited Particles for use in a pharmaceutical composition
EP1243524A3 (en) 2001-03-16 2004-04-07 Pfizer Products Inc. Pharmaceutical kit for oxygen-sensitive drugs
EP1241110A1 (en) 2001-03-16 2002-09-18 Pfizer Products Inc. Dispensing unit for oxygen-sensitive drugs
UA77656C2 (en) 2001-04-07 2007-01-15 Glaxo Group Ltd S-fluoromethyl ester of 6-alpha, 9-alpha-difluoro-17-alpha-[(2-furanylcarbonyl)oxy]-11-beta-hydroxy-16- alpha-methyl-3-oxoandrosta-1,4-dien-17-beta-carbothioacid as anti-inflammatory agent
DE10126924A1 (de) 2001-06-01 2002-12-05 Boehringer Ingelheim Pharma Inhalationskapseln
RU2312854C2 (ru) * 2001-09-14 2007-12-20 Глаксо Груп Лимитед Производные фенэтаноламина для лечения респираторных заболеваний
JP4739672B2 (ja) 2001-12-21 2011-08-03 ネクター セラピューティクス 湿気のバリアを有するカプセルパッケージ
GB0201677D0 (en) 2002-01-25 2002-03-13 Glaxo Group Ltd Medicament dispenser
GB0208608D0 (en) * 2002-04-13 2002-05-22 Glaxo Group Ltd Composition
US20030203141A1 (en) 2002-04-25 2003-10-30 Blum John B. Blister package
US20030235664A1 (en) 2002-06-20 2003-12-25 Rick Merical Films having a desiccant material incorporated therein and methods of use and manufacture
US8003179B2 (en) 2002-06-20 2011-08-23 Alcan Packaging Flexible France Films having a desiccant material incorporated therein and methods of use and manufacture
US20040131805A1 (en) 2002-06-20 2004-07-08 Merical Rick L. Films having a desiccant material incorporated therein and methods of use and manufacture
US20060269708A1 (en) 2002-06-20 2006-11-30 Rick Merical Films having a desiccant material incorporated therein and methods of use and manufacture
US20060236868A1 (en) 2003-05-19 2006-10-26 Bester Pansegrouw Dessicant container
GB0312148D0 (en) 2003-05-28 2003-07-02 Aventis Pharma Ltd Stabilized pharmaceutical products
SE527191C2 (sv) 2003-06-19 2006-01-17 Microdrug Ag Inhalatoranordning samt kombinerade doser av tiotropium och fluticason
GB0315889D0 (en) 2003-07-08 2003-08-13 Aventis Pharma Ltd Stable pharmaceutical products
BRPI0412329A (pt) 2003-07-09 2006-09-05 Chong Kun Dang Pharm Corp dispersão sólida de tacrolimus e método de processar a mesma
JP2009513529A (ja) * 2003-07-11 2009-04-02 グラクソ グループ リミテッド ステアリン酸マグネシウムを含む医薬製剤
GB0316341D0 (en) 2003-07-11 2003-08-13 Glaxo Group Ltd Pharmaceutical formulations
US20050072958A1 (en) 2003-10-02 2005-04-07 Thomas Powers Oxygen scavenger for low moisture environment and methods of using the same
DE602004030930D1 (de) * 2003-10-14 2011-02-17 Glaxo Group Ltd Muscarinische acetylcholin-rezeptor-antagonisten
WO2005044186A2 (en) 2003-10-28 2005-05-19 Glaxo Group Limited Inhalable pharmaceutical formulations employing desiccating agents and methods of administering the same
GB0326632D0 (en) * 2003-11-14 2003-12-17 Jagotec Ag Dry powder formulations
SE0303570L (sv) 2003-12-03 2005-06-04 Microdrug Ag Fukt-känslig medicinsk produkt
WO2005053647A1 (en) 2003-12-03 2005-06-16 Microdrug Ag Medical product containing tiotropium
CA2547245A1 (en) 2003-12-03 2005-06-16 Microdrug Ag Pre-metered dry powder inhaler for moisture-sensitive medicaments
SE0303270L (sv) 2003-12-03 2005-06-04 Microdrug Ag Metod för administration av tiotropium
SE0303569L (sv) 2003-12-03 2005-06-04 Microdrug Ag DPI för avlämning av fuktkänsliga medikament
SE0303269L (sv) 2003-12-03 2005-06-04 Microdrug Ag Medicinsk produkt
GB2410192B (en) 2004-01-23 2005-12-07 Eg Technology Ltd An inhaler
AR050902A1 (es) 2004-04-27 2006-12-06 Glaxo Group Ltd Compuesto de quinuclidina, composicion farmaceutica que lo comprende y su usopara preparar dicha composicion
GB0409703D0 (en) 2004-04-30 2004-06-02 Vectura Ltd Pharmaceutical compositions
RU2379033C2 (ru) * 2004-05-31 2010-01-20 Лабораториос Альмираль, С.А. Комбинации, содержащие антимускариновые средства и бета-адренергические агонисты
ES2257152B1 (es) 2004-05-31 2007-07-01 Laboratorios Almirall S.A. Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos.
SE530006C2 (sv) 2004-06-18 2008-02-05 Mederio Ag Inhalator som använder balja
SE0401654D0 (sv) 2004-06-24 2004-06-24 Astrazeneca Ab A support structure for a medicament
GB0416397D0 (en) 2004-07-22 2004-08-25 Glaxo Group Ltd Pharmaceutical formulations
EP1778626A1 (en) 2004-08-16 2007-05-02 Theravance, Inc. Compounds having beta2 adrenergic receptor agonist and muscarinic receptor antagonist activity
EA013776B1 (ru) 2004-10-21 2010-06-30 Бёрингер Ингельхайм Интернациональ Гмбх Блистерная упаковка для применения в ингаляторах
US7501011B2 (en) 2004-11-09 2009-03-10 Multisorb Technologies, Inc. Humidity control device
SE0402976L (sv) 2004-12-03 2006-06-04 Mederio Ag Medicinsk produkt
PE20061162A1 (es) 2004-12-06 2006-10-14 Smithkline Beecham Corp Compuestos derivados olefinicos de 8-azoniabiciclo[3.2.1]octanos
PE20060826A1 (es) 2004-12-06 2006-10-08 Smithkline Beecham Corp Derivado oleofinico de 8-azoniabiciclo[3.2.1]octano y combinacion farmaceutica que lo comprende
US7938580B2 (en) 2004-12-08 2011-05-10 Perfecseal, Inc. Sterilizable package with a high barrier to oxygen
JP2008525527A (ja) 2004-12-27 2008-07-17 キング・ファーマシューティカルズ・リサーチ・アンド・デベロプメント・インコーポレイティッド 脱酸素剤を有していてもよい酸素不浸透性包装の安定化甲状腺ホルモン組成物及び甲状腺ホルモン医薬組成物保管のためのその方法
US20060144733A1 (en) 2004-12-30 2006-07-06 3M Innovative Properties Company Container assembly and method for humidity control
EP1858528A2 (en) 2005-02-10 2007-11-28 Glaxo Group Limited Process for crystallizing lactose particles for use in pharmaceutical formulations
JP5156397B2 (ja) 2005-02-10 2013-03-06 グラクソ グループ リミテッド 予備分級技術を用いて乳糖を製造する方法及びその乳糖から形成させた医薬製剤
DE202005002409U1 (de) 2005-02-15 2005-07-07 Microdrug Ag Inhalierbares Tiotropium und Behälter dafür
DE202005004659U1 (de) 2005-03-22 2005-07-07 Microdrug Ag Vordosierter Trockenpulverinhalator für feuchtigkeitsempfindliche Medikamente
GB0507165D0 (en) 2005-04-08 2005-05-18 Glaxo Group Ltd Novel crystalline pharmaceutical product
JP4659523B2 (ja) 2005-04-26 2011-03-30 共同印刷株式会社 ブリスター用フィルム及びブリスター用包装容器
WO2006124556A2 (en) 2005-05-13 2006-11-23 Glaxo Group Limited Inhalable pharmaceutical formulations employing lactose anhydrate and methods of administering the same
DE102005022862A1 (de) 2005-05-18 2006-12-14 Airsec S.A.S Kapseln für Inhalatoren
GB0523653D0 (en) * 2005-11-21 2005-12-28 Novartis Ag Organic compounds
US20060278965A1 (en) 2005-06-10 2006-12-14 Foust Donald F Hermetically sealed package and methods of making the same
GB0515584D0 (en) 2005-07-28 2005-09-07 Glaxo Group Ltd Medicament dispenser
WO2007037748A1 (en) 2005-09-28 2007-04-05 Mederio Ag Inhaler device for moisture sensitive drugs and method of operating an inhaler device.
TWI389692B (zh) 2005-10-10 2013-03-21 Boehringer Ingelheim Int 用以吸入β-共效劑的氣溶膠調配物
GB0520794D0 (en) 2005-10-12 2005-11-23 Innovata Biomed Ltd Inhaler
DE502005006831D1 (de) 2005-10-18 2009-04-23 Alcan Tech & Man Ltd Kaltverformbares Laminat für Blisterbodenteile
EP1787800A1 (de) 2005-11-17 2007-05-23 Alcan Technology & Management Ltd. Kaltverformbares Laminat für Blisterbodenteile
AR058289A1 (es) 2005-12-12 2008-01-30 Glaxo Group Ltd Colector para ser usado en dispensador de medicamento
CA2642988C (en) 2006-02-27 2015-10-27 Takeda Pharmaceutical Company Limited Pharmaceutical product comprising a benzimidazole in combination with a desiccant
KR100764640B1 (ko) 2006-03-08 2007-10-10 세원셀론텍(주) 지방조직 수복용 키트
WO2007109606A2 (en) 2006-03-17 2007-09-27 Csp Technologies, Inc. Moisture-tight primary packaging for a dry powder inhaler
US20090123391A1 (en) 2006-03-22 2009-05-14 3M Innovative Properties Company Novel Formulations
CN101415428A (zh) 2006-03-22 2009-04-22 葛兰素集团有限公司 新型制剂
WO2007109824A1 (en) 2006-03-24 2007-10-04 Ian Simon Tracton Stable packaged dosage form and process therefor
CA2650813A1 (en) 2006-05-24 2007-11-29 Boehringer Ingelheim International Gmbh New long-acting drug combinations for the treatment of respiratory diseases
GB0615108D0 (en) 2006-07-28 2006-09-06 Glaxo Group Ltd Novel formulations
EP2046662A1 (de) 2006-08-03 2009-04-15 Merck Patent GmbH Packung enthaltend pharmazeutische darreichungsformen
JP2010500356A (ja) 2006-08-09 2010-01-07 グラクソ グループ リミテッド ラクトースの製造方法
US20090298742A1 (en) 2006-08-09 2009-12-03 Glaxo Group Limited Process for manufacturing lactose
FI20065636A0 (fi) 2006-10-04 2006-10-04 Lab Pharma Ltd Dessikanttijärjestelmä irtohaloitavien jauheiden kosteuden säätämiseksi
CA2667543A1 (en) 2006-10-26 2008-05-02 Boehringer Ingelheim International Gmbh New pharmaceutical combinations for treatment of respiratory and gastrointestinal disorders
US20080178559A1 (en) 2007-01-26 2008-07-31 Multisorb Technologies, Inc. Sorbent Packaging
CN101711184B (zh) 2007-03-29 2013-10-30 穆尔蒂索伯技术有限公司 选择供包装应用的吸附性复合材料屏障的方法
US7549272B2 (en) 2007-04-16 2009-06-23 Multisorb Technologies, Inc. Sorbent canister with beveled edges
WO2008135570A1 (en) 2007-05-07 2008-11-13 Airsec Container with moisture control capacity
UY31233A1 (es) 2007-07-21 2009-03-02 Unidades de envasado con un agente desecante
UY31235A1 (es) 2007-07-21 2009-03-02 Nuevos medicamentos pulverulentos que contienen tiotropio y salmeterol, asi como lactosa como excipiente
WO2009029029A1 (en) 2007-08-24 2009-03-05 Astrazeneca Ab Inhaler for powdered substances with desiccant compartment
KR20100063116A (ko) 2007-09-12 2010-06-10 글락소 그룹 리미티드 치료제들의 복합제
EP2080523A1 (en) 2008-01-15 2009-07-22 CHIESI FARMACEUTICI S.p.A. Compositions comprising an antimuscarinic and a long-acting beta-agonist
EP2254630A1 (de) 2008-02-20 2010-12-01 Boehringer Ingelheim International GmbH Pulverinhalatoren
JP4983657B2 (ja) 2008-03-11 2012-07-25 富士通株式会社 電子メール管理プログラム、該プログラムを記録した記録媒体、通信端末、および電子メール管理方法
EP2127628A1 (en) 2008-05-27 2009-12-02 Ranbaxy Laboratories Limited Unit dose pack
US9095324B2 (en) 2008-06-20 2015-08-04 Boston Scientific Scimed, Inc. Package assembly
BRPI0920707A2 (pt) 2008-10-02 2015-12-29 Respivert Ltd compostos
UY32297A (es) 2008-12-22 2010-05-31 Almirall Sa Sal mesilato de 5-(2-{[6-(2,2-difluoro-2-fenilitoxi) hexil]amino}-1-hidroxietil)-8-hidroxiquinolin-2( 1h)-ona como agonista del receptor b(beta)2 acrenérgico
PL3578169T3 (pl) * 2009-02-26 2024-09-02 Glaxo Group Limited Preparaty farmaceutyczne zawierające 4-{(1r)-2-[(6-{2-[(2,6-dichlorobenzylo)oksy]etoksy}heksylo)amino]-1-hydroksyetylo}-2-(hydroksymetylo)fenol
WO2010097114A1 (en) * 2009-02-26 2010-09-02 Glaxo Group Limited Novel combination of therapeutic agents
BRPI1009072B1 (pt) 2009-05-18 2021-06-22 Adamis Pharmaceuticals Corporation Dispositivo para inalação de pó seco e dispositivo para armazenamento de pó seco
EP2277799B8 (en) 2009-07-23 2012-04-11 Airsec S.A.S. Hydrated humidity control substance and process for its preparation
GB0921075D0 (en) 2009-12-01 2010-01-13 Glaxo Group Ltd Novel combination of the therapeutic agents
AU2011298315B2 (en) 2010-08-31 2014-08-28 Glaxo Group Limited Dry powder inhalation drug products exhibiting moisture control properties and methods of administering the same
WO2012168161A1 (en) 2011-06-08 2012-12-13 Glaxo Group Limited Combination comprising umeclidinium and a corticosteroid
BR112013031570A2 (pt) 2011-06-08 2017-03-21 Glaxo Group Ltd inalador de pó seco.
GB201222679D0 (en) 2012-12-17 2013-01-30 Glaxo Group Ltd Pharmaceutical combination products

Also Published As

Publication number Publication date
ES2979060T3 (es) 2024-09-24
MX351290B (es) 2017-10-09
GB0921075D0 (en) 2010-01-13
HUE066359T2 (hu) 2024-07-28
US12396986B2 (en) 2025-08-26
UA106775C2 (uk) 2014-10-10
AU2014204459A1 (en) 2014-07-31
US20180008582A1 (en) 2018-01-11
EA201290266A1 (ru) 2013-02-28
HUE036216T2 (hu) 2018-06-28
US20160095840A1 (en) 2016-04-07
US20120309725A1 (en) 2012-12-06
CL2012001432A1 (es) 2012-10-05
JP5816631B2 (ja) 2015-11-18
PT3335707T (pt) 2024-05-29
MY207466A (en) 2025-02-27
CY1120058T1 (el) 2018-09-05
US20200171009A1 (en) 2020-06-04
EP2506844A1 (en) 2012-10-10
CA2781487C (en) 2018-10-16
AU2018282427C1 (en) 2022-06-30
CN102724974A (zh) 2012-10-10
AU2016262698B2 (en) 2018-10-25
SI3335707T1 (sl) 2024-07-31
AU2010326798B2 (en) 2014-08-07
KR101830728B1 (ko) 2018-04-04
AU2016262698A1 (en) 2016-12-15
EP3335707B1 (en) 2024-04-17
US11090294B2 (en) 2021-08-17
EP4454645A1 (en) 2024-10-30
AU2018282427A1 (en) 2019-01-17
MA33853B1 (fr) 2012-12-03
HUS1800027I1 (hu) 2018-08-28
FR18C1022I1 (me) 2018-07-13
US20220235087A1 (en) 2022-07-28
CN107412229A (zh) 2017-12-01
US20220047565A1 (en) 2022-02-17
DK3335707T3 (da) 2024-05-21
AU2014204459B2 (en) 2016-08-25
PH12012501083A1 (en) 2016-12-23
RS56848B1 (sr) 2018-04-30
DK2506844T3 (en) 2018-02-05
LTC2506844I2 (lt) 2022-10-10
CA2781487A1 (en) 2011-06-09
MY184864A (en) 2021-04-28
TR201802921T4 (tr) 2018-03-21
EP3335707A1 (en) 2018-06-20
PT2506844T (pt) 2018-02-28
SG10201407864UA (en) 2014-12-30
KR20170061719A (ko) 2017-06-05
BR112012012925A2 (pt) 2016-08-16
SG181087A1 (en) 2012-07-30
SMT201800129T1 (it) 2018-05-02
MX2012006310A (es) 2012-06-19
CY2018017I2 (el) 2018-09-05
SI2506844T1 (en) 2018-04-30
AU2018282427B2 (en) 2021-04-01
JP2013512270A (ja) 2013-04-11
KR20120092163A (ko) 2012-08-20
SMT202400176T1 (it) 2024-07-09
PL3335707T3 (pl) 2024-07-29
NO2018018I2 (no) 2018-06-04
CY2018017I1 (el) 2018-09-05
CO6541613A2 (es) 2012-10-16
AU2023219901A1 (en) 2023-09-14
FIC20180019I1 (fi) 2018-05-30
AU2010326798A1 (en) 2012-06-21
CR20120265A (es) 2012-08-14
PE20130042A1 (es) 2013-02-09
US20250339413A1 (en) 2025-11-06
NZ600026A (en) 2014-06-27
HRP20180312T1 (hr) 2018-03-23
KR101742140B1 (ko) 2017-05-31
NO2506844T3 (me) 2018-05-19
LT3335707T (lt) 2024-06-10
ZA201203890B (en) 2013-11-27
HK1249407A1 (en) 2018-11-02
PL2506844T3 (pl) 2018-06-29
EA023839B1 (ru) 2016-07-29
HRP20240688T1 (hr) 2024-08-30
LUC00077I2 (en) 2018-08-14
US20240041846A1 (en) 2024-02-08
EP2506844B1 (en) 2017-12-20
LT2506844T (lt) 2018-03-12
WO2011067212A1 (en) 2011-06-09
AU2021204302A1 (en) 2021-07-22
DOP2012000148A (es) 2012-07-31
NO2018018I1 (no) 2018-06-04
LTPA2018011I1 (lt) 2018-06-25
RS65494B1 (sr) 2024-05-31
ES2659330T3 (es) 2018-03-14
IL219893A (en) 2017-01-31
PE20170915A1 (es) 2017-07-12
FI3335707T3 (fi) 2024-07-05
US9750726B2 (en) 2017-09-05
FR18C1022I2 (fr) 2020-03-20
IL219893A0 (en) 2012-07-31

Similar Documents

Publication Publication Date Title
ME02965B (me) Kombinacije antagonista muskarinskog receptora i agonista вета - 2 adrenoreceptora
HUS2200033I1 (hu) CGRP receptor antagonisták
CY2023022I1 (el) Ανταγωνιστες υποδοχεων cgrp αζαϊνδανιου καρβοξαμιδιου πιπεριδινονης
PL2513093T3 (pl) Nowi antagoniści receptora CCR2 i ich zastosowanie
EP2150115A4 (en) CYCLOPROPYLPYRROLIDINOREXIN Receptor Antagonists
DK2443104T3 (da) Disubstituerede phthalazin-hedgehog-sti-antagonister
EP2480576A4 (en) PCSK9 ANTAGONISTS
EP2427430A4 (en) 5-OXO-ETE RECEPTOR ANTAGONIST COMPOUNDS
EP2381778A4 (en) C5aR Antagonist
BRPI0910118A2 (pt) antagonistas de receptores do glucagon
EP2350060A4 (en) Melanocortin receptor AGONISTS
EP2485737A4 (en) NEW TRPA1 ANTAGONISTS
BRPI0815658A2 (pt) Aril-éter pirrolidina como antagonistas do receptor nk3
BRPI0913057A2 (pt) azetidinas e ciclobutanos como antagonistas de receptor de histamina h3
ATE519738T1 (de) Pyrrolidinarylether als nk3-rezeptorantagonisten
EP2254413A4 (en) IMIDAZOBENZAZEPIN-CGRP receptor antagonists
EP2480247A4 (en) NEW NPR-B AGONISTS
BRPI0806966A2 (pt) Combinação de um antagonista de receptor muscarínico e um agonista beta-2-adrenoceptor
BR112012003976A2 (pt) antagonistas de receptor glyt1 carbocíclico
EP2654421A4 (en) CONDENSED HETEROCYCLIC INDAN CARBOXAMIDE CGRP RECEPTOR ANTAGONISTS
BRPI0915834A2 (pt) 6-(1-piperazinil)-piridazinas substituídas como antagonistas do receptor de 5-ht6
BRPI1008008A2 (pt) usos de antagonistas do receptor de nk
EP2219660A4 (en) MODIFIED IL-4 MUTEIN RECEPTOR ANTAGONISTS
EP2271346A4 (en) MONOCYCLIC CGRP RECEPTOR ANTAGONISTS
EP2365748A4 (en) IMIDAZOISOINDOL neuropeptide S RECEPTOR ANTAGONISTS