MX351290B - Combinaciones de un antagonista de los receptores muscarínicos y un agonista del adreno-receptor beta-2. - Google Patents

Combinaciones de un antagonista de los receptores muscarínicos y un agonista del adreno-receptor beta-2.

Info

Publication number
MX351290B
MX351290B MX2012006310A MX2012006310A MX351290B MX 351290 B MX351290 B MX 351290B MX 2012006310 A MX2012006310 A MX 2012006310A MX 2012006310 A MX2012006310 A MX 2012006310A MX 351290 B MX351290 B MX 351290B
Authority
MX
Mexico
Prior art keywords
beta
receptor antagonist
combinations
muscarinic receptor
adrenoreceptor agonist
Prior art date
Application number
MX2012006310A
Other languages
English (en)
Other versions
MX2012006310A (es
Inventor
Baker Darrell
Bruce Mark
Crater Glenn
Noga Brian
Thomas Marian
Wire Patrick
Original Assignee
Glaxo Group Ltd Star
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41573013&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX351290(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxo Group Ltd Star filed Critical Glaxo Group Ltd Star
Publication of MX2012006310A publication Critical patent/MX2012006310A/es
Publication of MX351290B publication Critical patent/MX351290B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D75/36—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet or blank being recessed and the other formed of relatively stiff flat sheet material, e.g. blister packages, the recess or recesses being preformed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Molecular Biology (AREA)
  • Composite Materials (AREA)
  • Mechanical Engineering (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Se proporcionan combinaciones novedosas de un antagonista de los receptores muscarínicos de acetil-colina y un agonista beta-2 para su administración inhalada por medio de la nariz o la boca, y métodos para su uso.
MX2012006310A 2009-12-01 2010-11-29 Combinaciones de un antagonista de los receptores muscarínicos y un agonista del adreno-receptor beta-2. MX351290B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0921075.8A GB0921075D0 (en) 2009-12-01 2009-12-01 Novel combination of the therapeutic agents
PCT/EP2010/068429 WO2011067212A1 (en) 2009-12-01 2010-11-29 Combinations of a muscarinic receptor antagonist and a beta-2 adrenoreceptor agonist

Publications (2)

Publication Number Publication Date
MX2012006310A MX2012006310A (es) 2012-06-19
MX351290B true MX351290B (es) 2017-10-09

Family

ID=41573013

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012006310A MX351290B (es) 2009-12-01 2010-11-29 Combinaciones de un antagonista de los receptores muscarínicos y un agonista del adreno-receptor beta-2.

Country Status (41)

Country Link
US (7) US20120309725A1 (es)
EP (3) EP2506844B1 (es)
JP (1) JP5816631B2 (es)
KR (2) KR101830728B1 (es)
CN (2) CN107412229A (es)
AU (6) AU2010326798B2 (es)
BR (1) BR112012012925A2 (es)
CA (1) CA2781487C (es)
CL (1) CL2012001432A1 (es)
CO (1) CO6541613A2 (es)
CR (1) CR20120265A (es)
CY (2) CY1120058T1 (es)
DK (2) DK2506844T3 (es)
DO (1) DOP2012000148A (es)
EA (1) EA023839B1 (es)
ES (2) ES2659330T3 (es)
FI (1) FI3335707T3 (es)
FR (1) FR18C1022I2 (es)
GB (1) GB0921075D0 (es)
HK (1) HK1249407A1 (es)
HR (2) HRP20240688T1 (es)
HU (3) HUE036216T2 (es)
IL (1) IL219893A (es)
LT (3) LT2506844T (es)
LU (1) LUC00077I2 (es)
MA (1) MA33853B1 (es)
ME (1) ME02965B (es)
MX (1) MX351290B (es)
MY (1) MY184864A (es)
NO (2) NO2506844T3 (es)
NZ (1) NZ600026A (es)
PE (2) PE20130042A1 (es)
PL (2) PL3335707T3 (es)
PT (2) PT2506844T (es)
RS (2) RS56848B1 (es)
SG (2) SG10201407864UA (es)
SI (2) SI2506844T1 (es)
TR (1) TR201802921T4 (es)
UA (1) UA106775C2 (es)
WO (1) WO2011067212A1 (es)
ZA (1) ZA201203890B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR050902A1 (es) 2004-04-27 2006-12-06 Glaxo Group Ltd Compuesto de quinuclidina, composicion farmaceutica que lo comprende y su usopara preparar dicha composicion
LT3578169T (lt) 2009-02-26 2024-08-26 Glaxo Group Limited Farmaciniai preparatai, apimantys 4-{(1r)-2-[(6-{2-[(2,6-dichlorbenzil) oksi]etoksi}heksil)amino]-1-hidroksietil}-2-(hidroksimetil)fenolį
GB0921075D0 (en) * 2009-12-01 2010-01-13 Glaxo Group Ltd Novel combination of the therapeutic agents
WO2012028663A1 (en) * 2010-08-31 2012-03-08 Glaxo Group Limited Dry powder inhalation drug products exhibiting moisture control properties and methods of administering the same
PE20141048A1 (es) * 2011-06-08 2014-09-08 Glaxo Group Ltd Combinacion que comprende umeclidinio y un corticosteroide
RU2013153202A (ru) * 2011-06-08 2015-07-20 Глаксо Груп Лимитед Композиции для ингалятора сухого порошка, содержащие умеклидиний
ES2814336T3 (es) * 2012-04-13 2021-03-26 Glaxosmithkline Ip Dev Ltd Partículas de agregado
GB201222679D0 (en) 2012-12-17 2013-01-30 Glaxo Group Ltd Pharmaceutical combination products
GB201305825D0 (en) 2013-03-28 2013-05-15 Vectura Ltd New use
EP3148521B1 (en) 2014-05-28 2019-12-18 GlaxoSmithKline Intellectual Property Development Limited Fluticasone furoate in the treatment of copd
TR201407010A2 (tr) 2014-06-16 2015-12-21 Arven Ilac Sanayi Ve Ticaret Anonim Sirketi Vilanterol formülasyonları.
EP2957552B1 (en) 2014-06-16 2020-01-22 Arven Ilac Sanayi Ve Ticaret A.S. Vilanterol formulations
CA2952760A1 (en) 2014-06-18 2015-12-23 Cipla Limited Pharmaceutical composition comprising a beta-2-agonist and anticholinergic agent
EP3880169A1 (en) * 2018-11-12 2021-09-22 Kindeva Drug Delivery L.P. Umeclidinium and vilanterol formulation and inhaler
CN111840256A (zh) * 2019-04-29 2020-10-30 上海谷森医药有限公司 一种雾化吸入剂及其制备方法
WO2020237151A1 (en) 2019-05-23 2020-11-26 Huang Cai Gu Inhalable formulation of a solution containing vilanterol trifenatate and umeclidinium bromide
US11304897B2 (en) * 2020-06-09 2022-04-19 Anovent Pharmaceutical (U.S.), Llc Pharmaceutical formulation containing umeclidinium bromide and vilanterol trifenatate

Family Cites Families (181)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB124009A (en) 1918-01-12 1919-03-12 Walter Edward Kimber Improvements in and connected with the Manufacture of Tools for Turning, Planing, Boring and similar purposes.
GB124010A (en) 1919-01-10 1919-03-20 Rene Emile Dior Improved Process for the Manufacture of Synthetic Resins.
GB1242211A (en) 1967-08-08 1971-08-11 Fisons Pharmaceuticals Ltd Pharmaceutical composition
GB1381872A (en) 1971-06-22 1975-01-29 Fisons Ltd Pharmaceutical compositions for inhalation
GB1424432A (en) 1972-03-25 1976-02-11 Degussa Pharmaceutical compositions
CY1308A (en) 1979-12-06 1985-12-06 Glaxo Group Ltd Device for dispensing medicaments
CY1492A (en) 1981-07-08 1990-02-16 Draco Ab Powder inhalator
AT396333B (de) 1982-10-08 1993-08-25 Glaxo Group Ltd Vorrichtung zur verabreichung von medikamenten an patienten, einrichtung mit mehreren solchen vorrichtungen und traeger mit medikamentbehaeltern hiefuer
US4778054A (en) 1982-10-08 1988-10-18 Glaxo Group Limited Pack for administering medicaments to patients
GB2169265B (en) 1982-10-08 1987-08-12 Glaxo Group Ltd Pack for medicament
DK163640C (da) 1985-07-30 1992-08-17 Glaxo Group Ltd Apparat til administrering af medikamenter
GB8530365D0 (en) 1985-12-10 1986-01-22 Univ Bath Manufacture of moulded products
IT1204826B (it) 1986-03-04 1989-03-10 Chiesi Farma Spa Composizioni farmaceutiche per inalazione
CA1329526C (en) 1987-08-20 1994-05-17 Hiroshi Ikura Powdery medicine applicator device
US4994276A (en) 1988-09-19 1991-02-19 Edward Mendell Co., Inc. Directly compressible sustained release excipient
GB8820353D0 (en) 1988-08-26 1988-09-28 Staniforth J N Controlled release tablet
US5135757A (en) 1988-09-19 1992-08-04 Edward Mendell Co., Inc. Compressible sustained release solid dosage forms
US5376386A (en) 1990-01-24 1994-12-27 British Technology Group Limited Aerosol carriers
GB9004781D0 (en) 1990-03-02 1990-04-25 Glaxo Group Ltd Device
HU213221B (en) 1990-03-02 1997-03-28 Glaxo Group Ltd Inhalation device and medicine packet for device
UA26230A (uk) 1990-03-02 1999-07-19 Глексо Груп Лімітед Іhгалятор для спільhого використаhhя з лікувальhим блоком і лікувальhий блок
US6536427B2 (en) 1990-03-02 2003-03-25 Glaxo Group Limited Inhalation device
FR2660634B1 (fr) 1990-04-06 1992-10-16 Airsec Ind Sa Conditionnement pour produits necessitant l'usage d'un agent deshydratant.
JPH0471560A (ja) 1990-07-10 1992-03-06 Mect Corp 包装体
US5145684A (en) 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
DE4140689B4 (de) 1991-12-10 2007-11-22 Boehringer Ingelheim Kg Inhalationspulver und Verfahren zu ihrer Herstellung
ES2177544T3 (es) 1992-06-12 2002-12-16 Teijin Ltd Polvo ultrafinno para inhalar y metodo para su preparacion.
AU660824B2 (en) 1992-06-12 1995-07-06 Teijin Limited Pharmaceutical preparation for intra-airway administration
GB2269992A (en) 1992-08-14 1994-03-02 Rh Ne Poulenc Rorer Limited Powder inhalation formulations
ES2102210T3 (es) 1992-09-09 1997-07-16 Fisons Plc Envase para medicamentos.
SE9203743D0 (sv) 1992-12-11 1992-12-11 Astra Ab Efficient use
AU683036B2 (en) 1992-12-18 1997-10-30 Merck Sharp & Dohme Corp. Inhaler for powdered medications
US5441060A (en) 1993-02-08 1995-08-15 Duke University Dry powder delivery system
KR100321649B1 (ko) 1993-03-17 2002-07-22 미네소타 마이닝 앤드 매뉴팩춰링 캄파니 에스테르,아미드또는머캅토에스테르로부터유도된분산보조제를함유하는에어로졸제제
US5730785A (en) 1993-04-01 1998-03-24 Multisorb Technologies, Inc. Desiccant canister for desiccants and other particulate material
US5506203C1 (en) 1993-06-24 2001-02-06 Astra Ab Systemic administration of a therapeutic preparation
IS1796B (is) 1993-06-24 2001-12-31 Ab Astra Fjölpeptíð lyfjablanda til innöndunar sem einnig inniheldur eykjaefnasamband
DE4323636A1 (de) 1993-07-15 1995-01-19 Hoechst Ag Arzneistoffzubereitungen aus umhüllten, schwerstwasserlöslichen Arzneistoffen für Inhalationsarzneiformen und Verfahren zu ihrer Herstellung
GB9322014D0 (en) 1993-10-26 1993-12-15 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
US5503662A (en) 1994-03-29 1996-04-02 Multiform Desiccants, Inc. Canister with porous plastic ends
FI95441C (fi) 1994-05-31 1996-02-12 Leiras Oy Inhalointilaitteen lääkeainekammio
US5641425A (en) 1994-09-08 1997-06-24 Multiform Desiccants, Inc. Oxygen absorbing composition
US6156231A (en) 1994-09-08 2000-12-05 Multisorb Technologies, Inc. Oxygen absorbing composition with cover layer
SA95160463B1 (ar) 1994-12-22 2005-10-04 استرا أكتيبولاج مساحيق للاستنشاق
GB9501841D0 (en) 1995-01-31 1995-03-22 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
DE69611608T2 (de) 1995-04-19 2001-05-03 Capitol Vial, Inc. Geschlossener behälter mit trockenmittel
US6279736B1 (en) 1995-04-19 2001-08-28 Capitol Specialty Plastics, Inc. Barrier pack having an absorbing agent applied to the interior of the pack
GB9515182D0 (en) 1995-07-24 1995-09-20 Co Ordinated Drug Dev Improvements in and relating to powders for use in dry powder inhalers
GB9700226D0 (en) 1997-01-08 1997-02-26 Glaxo Group Ltd Inhalation device
US6103141A (en) 1997-01-23 2000-08-15 Multisorb Technologies, Inc. Desiccant deposit
US6126919A (en) 1997-02-07 2000-10-03 3M Innovative Properties Company Biocompatible compounds for pharmaceutical drug delivery systems
AU6700998A (en) 1997-03-14 1998-09-29 University Of Houston, The Methods for making fluorinated surface modifying agents, methods of using same and products made using same
US5985415A (en) 1997-11-17 1999-11-16 Reconnx, Inc. Finger joint architecture for wood products, and method and apparatus for formation thereof
US6086376A (en) 1998-01-30 2000-07-11 Rtp Pharma Inc. Dry aerosol suspension of phospholipid-stabilized drug microparticles in a hydrofluoroalkane propellant
DE69921297T2 (de) 1998-02-05 2006-02-02 E.I. du Pont de Nemours & Co., Inc., Wilmington Pflanzenwachstumsmedium mit hydrophilem Membrane und Verwendung der Membrane zur Kontrolle der Feuchtigkeit
PL343491A1 (en) 1998-04-18 2001-08-27 Glaxo Group Ltd Pharmaceutical aerosol formulation
US7521068B2 (en) 1998-11-12 2009-04-21 Elan Pharma International Ltd. Dry powder aerosols of nanoparticulate drugs
US20070212422A1 (en) 1999-11-10 2007-09-13 Manfred Keller Dry powder for inhalation
EP1131059B1 (de) 1998-11-13 2003-03-05 Jago Research Ag Trockenpulver zur inhalation
GB9827145D0 (en) 1998-12-09 1999-02-03 Co Ordinated Drug Dev Improvements in or relating to powders
US6315112B1 (en) 1998-12-18 2001-11-13 Smithkline Beecham Corporation Method and package for storing a pressurized container containing a drug
US6352152B1 (en) 1998-12-18 2002-03-05 Smithkline Beecham Corporation Method and package for storing a pressurized container containing a drug
US6119853A (en) 1998-12-18 2000-09-19 Glaxo Wellcome Inc. Method and package for storing a pressurized container containing a drug
US6390291B1 (en) 1998-12-18 2002-05-21 Smithkline Beecham Corporation Method and package for storing a pressurized container containing a drug
PT1158958E (pt) 1999-03-05 2007-08-13 Chiesi Farma Spa ''composições farmacêuticas em pó, melhoradas, para inalação''
IT1309592B1 (it) 1999-03-05 2002-01-24 Chiesi Farma Spa Particelle veicolo modificate da utilizzarsi nella preparazione diformulazioni farmaceutiche sotto forma di polimeri per inalazione e
USD440874S1 (en) 1999-07-29 2001-04-24 The Gillette Company Container
CZ20021198A3 (cs) 1999-10-11 2002-09-11 Ml Laboratories Plc Zařízení pro podávání léčiva s povrchovou úpravou odolnou proti vlhkosti
DE19957802A1 (de) 1999-12-01 2001-06-07 Trw Repa Gmbh Gurtaufrollersystem
GB0008660D0 (en) 2000-04-07 2000-05-31 Arakis Ltd The treatment of respiratory diseases
EP1274433A1 (en) 2000-04-13 2003-01-15 Innovata Biomed Limited Medicaments for treating respiratory disorders comprising formoterol and fluticasone
PE20011227A1 (es) 2000-04-17 2002-01-07 Chiesi Farma Spa Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros
AU2001264594A1 (en) 2000-05-15 2001-11-26 Glaxo Group Limited Aerosol mdi overcap containing desiccant
GB0015043D0 (en) 2000-06-21 2000-08-09 Glaxo Group Ltd Medicament dispenser
AU2001270074A1 (en) 2000-06-22 2002-01-02 Glaxo Group Limited Method and package for storing a pressurized container containing a drug
US6759398B2 (en) 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
PT2348032E (pt) 2000-08-05 2015-10-14 Glaxo Group Ltd Éster s-fluorometílico do ácido 6.alfa.,9.alfa.-difluoro- 17.alfa.-'(2-furanilcarboxil)oxi]-11.beta.-hidroxi-16.alfa.- metil-3-oxo-androsta-1,4-dieno-17-carbotióico como um agente anti-inflamatório
GB0019172D0 (en) 2000-08-05 2000-09-27 Glaxo Group Ltd Novel compounds
DE10056855A1 (de) 2000-11-16 2002-05-29 Lohmann Therapie Syst Lts Verbundlaminat mit Sauerstoff und Feuchtigkeit absorbierender Schicht und Verfahren zu seiner Herstellung
EP2168571B1 (en) 2000-11-30 2018-08-22 Vectura Limited Particles for use in a Pharmaceutical Composition
EP2283818B1 (en) 2000-11-30 2017-08-02 Vectura Limited Method of making particles for use in a pharmaceutical composition
EP1243524A3 (en) 2001-03-16 2004-04-07 Pfizer Products Inc. Pharmaceutical kit for oxygen-sensitive drugs
EP1241110A1 (en) 2001-03-16 2002-09-18 Pfizer Products Inc. Dispensing unit for oxygen-sensitive drugs
UA77656C2 (en) 2001-04-07 2007-01-15 Glaxo Group Ltd S-fluoromethyl ester of 6-alpha, 9-alpha-difluoro-17-alpha-[(2-furanylcarbonyl)oxy]-11-beta-hydroxy-16- alpha-methyl-3-oxoandrosta-1,4-dien-17-beta-carbothioacid as anti-inflammatory agent
DE10126924A1 (de) 2001-06-01 2002-12-05 Boehringer Ingelheim Pharma Inhalationskapseln
HU228508B1 (en) 2001-09-14 2013-03-28 Glaxo Group Ltd Phenethanolamine derivatives and pharmaceutical composition containing them
JP4739672B2 (ja) 2001-12-21 2011-08-03 ネクター セラピューティクス 湿気のバリアを有するカプセルパッケージ
GB0201677D0 (en) 2002-01-25 2002-03-13 Glaxo Group Ltd Medicament dispenser
GB0208608D0 (en) * 2002-04-13 2002-05-22 Glaxo Group Ltd Composition
US20030203141A1 (en) 2002-04-25 2003-10-30 Blum John B. Blister package
US20060269708A1 (en) 2002-06-20 2006-11-30 Rick Merical Films having a desiccant material incorporated therein and methods of use and manufacture
US20040131805A1 (en) 2002-06-20 2004-07-08 Merical Rick L. Films having a desiccant material incorporated therein and methods of use and manufacture
US8003179B2 (en) 2002-06-20 2011-08-23 Alcan Packaging Flexible France Films having a desiccant material incorporated therein and methods of use and manufacture
US20030235664A1 (en) 2002-06-20 2003-12-25 Rick Merical Films having a desiccant material incorporated therein and methods of use and manufacture
WO2004101390A1 (en) 2003-05-19 2004-11-25 Stopak (Pty) Ltd Dessicant container
GB0312148D0 (en) 2003-05-28 2003-07-02 Aventis Pharma Ltd Stabilized pharmaceutical products
SE527191C2 (sv) 2003-06-19 2006-01-17 Microdrug Ag Inhalatoranordning samt kombinerade doser av tiotropium och fluticason
GB0315889D0 (en) 2003-07-08 2003-08-13 Aventis Pharma Ltd Stable pharmaceutical products
KR100486016B1 (ko) 2003-07-09 2005-04-29 주식회사종근당 타크로리무스의 속용성 고체분산체 및 이의 제조방법
GB0316341D0 (en) 2003-07-11 2003-08-13 Glaxo Group Ltd Pharmaceutical formulations
JP2009513529A (ja) * 2003-07-11 2009-04-02 グラクソ グループ リミテッド ステアリン酸マグネシウムを含む医薬製剤
US20050072958A1 (en) 2003-10-02 2005-04-07 Thomas Powers Oxygen scavenger for low moisture environment and methods of using the same
SG147436A1 (en) 2003-10-14 2008-11-28 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists
WO2005044186A2 (en) 2003-10-28 2005-05-19 Glaxo Group Limited Inhalable pharmaceutical formulations employing desiccating agents and methods of administering the same
GB0326632D0 (en) * 2003-11-14 2003-12-17 Jagotec Ag Dry powder formulations
PL1691783T3 (pl) 2003-12-03 2010-05-31 Boehringer Ingelheim Int Inhalator suchego proszku ze wstępnym odmierzaniem do leków wrażliwych na wilgoć
SE0303570L (sv) 2003-12-03 2005-06-04 Microdrug Ag Fukt-känslig medicinsk produkt
SE0303569L (sv) 2003-12-03 2005-06-04 Microdrug Ag DPI för avlämning av fuktkänsliga medikament
SE0303270L (sv) 2003-12-03 2005-06-04 Microdrug Ag Metod för administration av tiotropium
SE0303269L (sv) 2003-12-03 2005-06-04 Microdrug Ag Medicinsk produkt
AU2004294889B2 (en) 2003-12-03 2010-08-26 Boehringer Ingelheim International Gmbh Medical product containing tiotropium
GB2410192B (en) 2004-01-23 2005-12-07 Eg Technology Ltd An inhaler
AR050902A1 (es) 2004-04-27 2006-12-06 Glaxo Group Ltd Compuesto de quinuclidina, composicion farmaceutica que lo comprende y su usopara preparar dicha composicion
GB0409703D0 (en) 2004-04-30 2004-06-02 Vectura Ltd Pharmaceutical compositions
RS50786B (sr) * 2004-05-31 2010-08-31 Laboratorios Almirall S.A. Kombinacije koje sadrže antimuskarinska sredstva i beta-adrenergične agoniste
ES2257152B1 (es) 2004-05-31 2007-07-01 Laboratorios Almirall S.A. Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos.
SE530006C2 (sv) 2004-06-18 2008-02-05 Mederio Ag Inhalator som använder balja
SE0401654D0 (sv) 2004-06-24 2004-06-24 Astrazeneca Ab A support structure for a medicament
GB0416397D0 (en) 2004-07-22 2004-08-25 Glaxo Group Ltd Pharmaceutical formulations
JP2008510014A (ja) 2004-08-16 2008-04-03 セラヴァンス， インコーポレーテッド β２アドレナリン作用性レセプターアゴニスト活性およびムスカリン性レセプターアンタゴニスト活性を有する化合物
JP5566576B2 (ja) 2004-10-21 2014-08-06 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 吸入器用ブリスタ
US7501011B2 (en) 2004-11-09 2009-03-10 Multisorb Technologies, Inc. Humidity control device
SE0402976L (sv) 2004-12-03 2006-06-04 Mederio Ag Medicinsk produkt
PE20060826A1 (es) 2004-12-06 2006-10-08 Smithkline Beecham Corp Derivado oleofinico de 8-azoniabiciclo[3.2.1]octano y combinacion farmaceutica que lo comprende
PE20061162A1 (es) 2004-12-06 2006-10-14 Smithkline Beecham Corp Compuestos derivados olefinicos de 8-azoniabiciclo[3.2.1]octanos
US7938580B2 (en) 2004-12-08 2011-05-10 Perfecseal, Inc. Sterilizable package with a high barrier to oxygen
US20060183804A1 (en) 2004-12-27 2006-08-17 Brinkman Kyle R Oxygen-impervious packaging with optional oxygen scavenger, stabilized thyroid hormone compositions and methods for storing thyroid hormone pharmaceutical compositions
US20060144733A1 (en) 2004-12-30 2006-07-06 3M Innovative Properties Company Container assembly and method for humidity control
US20090029901A1 (en) 2005-02-10 2009-01-29 Marian Wood-Kaczmar Process for Crystallizing Lactose Particles for Use in Pharmaceutical Formulations
EP1848444B1 (en) 2005-02-10 2016-11-09 Glaxo Group Limited Processes for making lactose utilizing pre-classification techniques and pharmaceutical formulations formed therefrom
DE202005002409U1 (de) 2005-02-15 2005-07-07 Microdrug Ag Inhalierbares Tiotropium und Behälter dafür
DE202005004659U1 (de) 2005-03-22 2005-07-07 Microdrug Ag Vordosierter Trockenpulverinhalator für feuchtigkeitsempfindliche Medikamente
GB0507165D0 (en) 2005-04-08 2005-05-18 Glaxo Group Ltd Novel crystalline pharmaceutical product
JP4659523B2 (ja) 2005-04-26 2011-03-30 共同印刷株式会社 ブリスター用フィルム及びブリスター用包装容器
WO2006124556A2 (en) 2005-05-13 2006-11-23 Glaxo Group Limited Inhalable pharmaceutical formulations employing lactose anhydrate and methods of administering the same
DE102005022862A1 (de) 2005-05-18 2006-12-14 Airsec S.A.S Kapseln für Inhalatoren
GB0523653D0 (en) * 2005-11-21 2005-12-28 Novartis Ag Organic compounds
US20060278965A1 (en) 2005-06-10 2006-12-14 Foust Donald F Hermetically sealed package and methods of making the same
GB0515584D0 (en) 2005-07-28 2005-09-07 Glaxo Group Ltd Medicament dispenser
EP1937341A1 (en) 2005-09-28 2008-07-02 Mederio AG Inhaler device for moisture sensitive drugs and method of operating an inhaler device.
GB0520794D0 (en) 2005-10-12 2005-11-23 Innovata Biomed Ltd Inhaler
PL1780005T3 (pl) 2005-10-18 2009-07-31 Alcan Tech & Management Ltd Laminat formowalny na zimno dla korpusu blistra
EP1787800A1 (de) 2005-11-17 2007-05-23 Alcan Technology & Management Ltd. Kaltverformbares Laminat für Blisterbodenteile
AR058289A1 (es) 2005-12-12 2008-01-30 Glaxo Group Ltd Colector para ser usado en dispensador de medicamento
EP1990052B1 (en) 2006-02-27 2012-05-16 Takeda Pharmaceutical Company Limited Pharmaceutical package comprising 2-ethoxy-1-{[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl}-1h-benzimidazole-7-carboxylic acid (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl or 2-cyclopropyl-1-{[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl}-1h-benzimidazole-7-carboxylic acid (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl and a desiccant.
KR100764640B1 (ko) 2006-03-08 2007-10-10 세원셀론텍(주) 지방조직 수복용 키트
WO2007109606A2 (en) 2006-03-17 2007-09-27 Csp Technologies, Inc. Moisture-tight primary packaging for a dry powder inhaler
AU2007226899A1 (en) 2006-03-22 2007-09-27 3M Innovative Properties Company Novel formulations
WO2007117911A2 (en) 2006-03-22 2007-10-18 3M Innovative Properties Company Novel formulations
WO2007109824A1 (en) 2006-03-24 2007-10-04 Ian Simon Tracton Stable packaged dosage form and process therefor
CA2650813A1 (en) 2006-05-24 2007-11-29 Boehringer Ingelheim International Gmbh New long-acting drug combinations for the treatment of respiratory diseases
GB0615108D0 (en) 2006-07-28 2006-09-06 Glaxo Group Ltd Novel formulations
RU2448026C2 (ru) 2006-08-03 2012-04-20 Мерк Патент Гмбх Упаковка, содержащая фармацевтические лекарственные формы
WO2008021142A2 (en) 2006-08-09 2008-02-21 Glaxo Group Limited Process for manufacturing lactose
JP2010500373A (ja) 2006-08-09 2010-01-07 グラクソ グループ リミテッド ラクトースの製造方法
FI20065636A0 (fi) 2006-10-04 2006-10-04 Lab Pharma Ltd Dessikanttijärjestelmä irtohaloitavien jauheiden kosteuden säätämiseksi
JP2010507617A (ja) 2006-10-26 2010-03-11 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 呼吸器系及び消化器系障害の治療用の新規な医薬組成物
US20080178559A1 (en) 2007-01-26 2008-07-31 Multisorb Technologies, Inc. Sorbent Packaging
KR101358054B1 (ko) 2007-03-29 2014-02-13 멀티서브 테크놀로지스 인코포레이티드 패키징 용도를 위한 흡착성 복합물 장벽을 선택하는 방법
US7549272B2 (en) 2007-04-16 2009-06-23 Multisorb Technologies, Inc. Sorbent canister with beveled edges
US20100319303A1 (en) 2007-05-07 2010-12-23 Airsec Container with moisture control capacity
UY31235A1 (es) 2007-07-21 2009-03-02 Nuevos medicamentos pulverulentos que contienen tiotropio y salmeterol, asi como lactosa como excipiente
UY31233A1 (es) 2007-07-21 2009-03-02 Unidades de envasado con un agente desecante
WO2009029029A1 (en) 2007-08-24 2009-03-05 Astrazeneca Ab Inhaler for powdered substances with desiccant compartment
BRPI0816255A2 (pt) 2007-09-12 2015-03-17 Glaxo Group Ltd Produto farmacêutico, uso do produto, método para a profilaxia ou o tratamento de doenças, e, composição farmaceuticamente aceitável
EP2080523A1 (en) 2008-01-15 2009-07-22 CHIESI FARMACEUTICI S.p.A. Compositions comprising an antimuscarinic and a long-acting beta-agonist
JP2011512209A (ja) 2008-02-20 2011-04-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 粉末吸入器
JP4983657B2 (ja) 2008-03-11 2012-07-25 富士通株式会社 電子メール管理プログラム、該プログラムを記録した記録媒体、通信端末、および電子メール管理方法
EP2127628A1 (en) 2008-05-27 2009-12-02 Ranbaxy Laboratories Limited Unit dose pack
US9095324B2 (en) 2008-06-20 2015-08-04 Boston Scientific Scimed, Inc. Package assembly
MY159230A (en) 2008-10-02 2016-12-30 Respivert Ltd P38 map kinase inhibitors
UY32297A (es) 2008-12-22 2010-05-31 Almirall Sa Sal mesilato de 5-(2-{[6-(2,2-difluoro-2-fenilitoxi) hexil]amino}-1-hidroxietil)-8-hidroxiquinolin-2( 1h)-ona como agonista del receptor b(beta)2 acrenérgico
WO2010097114A1 (en) * 2009-02-26 2010-09-02 Glaxo Group Limited Novel combination of therapeutic agents
LT3578169T (lt) * 2009-02-26 2024-08-26 Glaxo Group Limited Farmaciniai preparatai, apimantys 4-{(1r)-2-[(6-{2-[(2,6-dichlorbenzil) oksi]etoksi}heksil)amino]-1-hidroksietil}-2-(hidroksimetil)fenolį
EP3260152B1 (en) 2009-05-18 2019-12-18 Adamis Pharmaceuticals Corporation Dry powder inhalers
EP2277799B8 (en) 2009-07-23 2012-04-11 Airsec S.A.S. Hydrated humidity control substance and process for its preparation
GB0921075D0 (en) 2009-12-01 2010-01-13 Glaxo Group Ltd Novel combination of the therapeutic agents
WO2012028663A1 (en) 2010-08-31 2012-03-08 Glaxo Group Limited Dry powder inhalation drug products exhibiting moisture control properties and methods of administering the same
PE20141048A1 (es) 2011-06-08 2014-09-08 Glaxo Group Ltd Combinacion que comprende umeclidinio y un corticosteroide
RU2013153202A (ru) 2011-06-08 2015-07-20 Глаксо Груп Лимитед Композиции для ингалятора сухого порошка, содержащие умеклидиний
GB201222679D0 (en) 2012-12-17 2013-01-30 Glaxo Group Ltd Pharmaceutical combination products

Also Published As

Publication number Publication date
AU2014204459A1 (en) 2014-07-31
NO2018018I1 (no) 2018-06-04
US20160095840A1 (en) 2016-04-07
AU2021204302A1 (en) 2021-07-22
PE20170915A1 (es) 2017-07-12
PL3335707T3 (pl) 2024-07-29
AU2023219901A1 (en) 2023-09-14
EP3335707A1 (en) 2018-06-20
EA023839B1 (ru) 2016-07-29
MX2012006310A (es) 2012-06-19
CY2018017I1 (el) 2018-09-05
DK2506844T3 (en) 2018-02-05
FR18C1022I1 (es) 2018-07-13
CO6541613A2 (es) 2012-10-16
HUE036216T2 (hu) 2018-06-28
AU2016262698A1 (en) 2016-12-15
KR101742140B1 (ko) 2017-05-31
US20120309725A1 (en) 2012-12-06
EP3335707B1 (en) 2024-04-17
PE20130042A1 (es) 2013-02-09
KR101830728B1 (ko) 2018-04-04
LTPA2018011I1 (lt) 2018-06-25
UA106775C2 (uk) 2014-10-10
ES2979060T3 (es) 2024-09-24
FI3335707T3 (fi) 2024-07-05
US20180008582A1 (en) 2018-01-11
AU2018282427B2 (en) 2021-04-01
HUS1800027I1 (hu) 2018-08-28
HUE066359T2 (hu) 2024-07-28
CA2781487C (en) 2018-10-16
SI2506844T1 (en) 2018-04-30
ZA201203890B (en) 2013-11-27
FR18C1022I2 (fr) 2020-03-20
PT2506844T (pt) 2018-02-28
IL219893A (en) 2017-01-31
RS56848B1 (sr) 2018-04-30
US9750726B2 (en) 2017-09-05
US20240041846A1 (en) 2024-02-08
CY2018017I2 (el) 2018-09-05
US11090294B2 (en) 2021-08-17
EP4454645A1 (en) 2024-10-30
JP5816631B2 (ja) 2015-11-18
AU2010326798A1 (en) 2012-06-21
CA2781487A1 (en) 2011-06-09
IL219893A0 (en) 2012-07-31
LTC2506844I2 (lt) 2022-10-10
SG10201407864UA (en) 2014-12-30
MY184864A (en) 2021-04-28
HRP20240688T1 (hr) 2024-08-30
KR20170061719A (ko) 2017-06-05
ME02965B (me) 2018-07-20
PL2506844T3 (pl) 2018-06-29
TR201802921T4 (tr) 2018-03-21
NO2506844T3 (es) 2018-05-19
LT2506844T (lt) 2018-03-12
DK3335707T3 (da) 2024-05-21
LT3335707T (lt) 2024-06-10
EA201290266A1 (ru) 2013-02-28
AU2014204459B2 (en) 2016-08-25
LUC00077I2 (en) 2018-08-14
AU2010326798B2 (en) 2014-08-07
CL2012001432A1 (es) 2012-10-05
CN102724974A (zh) 2012-10-10
US20220047565A1 (en) 2022-02-17
RS65494B1 (sr) 2024-05-31
AU2018282427C1 (en) 2022-06-30
ES2659330T3 (es) 2018-03-14
NO2018018I2 (no) 2018-06-04
SG181087A1 (en) 2012-07-30
AU2016262698B2 (en) 2018-10-25
GB0921075D0 (en) 2010-01-13
HRP20180312T1 (hr) 2018-03-23
WO2011067212A1 (en) 2011-06-09
MA33853B1 (fr) 2012-12-03
HK1249407A1 (zh) 2018-11-02
CR20120265A (es) 2012-08-14
EP2506844B1 (en) 2017-12-20
JP2013512270A (ja) 2013-04-11
EP2506844A1 (en) 2012-10-10
SI3335707T1 (sl) 2024-07-31
BR112012012925A2 (pt) 2016-08-16
DOP2012000148A (es) 2012-07-31
KR20120092163A (ko) 2012-08-20
US20220235087A1 (en) 2022-07-28
CN107412229A (zh) 2017-12-01
US20200171009A1 (en) 2020-06-04
NZ600026A (en) 2014-06-27
PT3335707T (pt) 2024-05-29
CY1120058T1 (el) 2018-09-05
AU2018282427A1 (en) 2019-01-17

Similar Documents

Publication Publication Date Title
LUC00077I2 (en) Combinations of a muscarinic receptor antagonist and a beta-2 adrenoreceptor agonist
MX2010002781A (es) Combinacion novedosa de angentes terapeuticos.
JO3346B1 (ar) مواد مضادة C5aR
IN2012DN02735A (es)
IN2012DN02702A (es)
IN2012DN00754A (es)
TN2012000082A1 (en) Use of nicotinic acetylcholine receptor alpha 7 activators
MY163055A (en) Polycyclic antagonists of lysophosphatidic acid receptors
JO2831B1 (en) Quinclidine carbonate derivatives and pharmaceutical compounds
TW200633706A (en) Medical combinations
UA107334C2 (ru) Производные аминоэфиров алкалоидов и их лекарственные композиции
MX2009004662A (es) Compuestos de pirazolina como antagonistas receptores de mineralocorticoides.
UA98839C2 (en) N,n-disubstituted aminoalkylbiphenyl antagonists of prostaglandin d2 receptors
PH12015501398A1 (en) New cyclohexyl and quinuclidinyl carbamate derivatives having beta2 adrenergic agonist and m3 muscarinic antagonist activity
WO2014066799A3 (en) Modulators of resistant androgen receptor
MX2021004883A (es) Metodos y composiciones para tratar apnea del sue?o.
MX2009004866A (es) Vacuna para enfermedad de lyme canina.
WO2008097536A3 (en) Compositions and methods for treating psychiatric diseases and disorders
UA98938C2 (ru) Лечение психологических состояний с применением антагонистов мускариновых рецепторов м1
MX2011008458A (es) Metodos para preparar agonistas y antagonistas del receptor s1p.
GEP20135792B (en) Pharmaceutical compositions based on kinin b2 receptor antagonists and corticosteroids, and use of the same
WO2012012147A3 (en) Methods and compositions for treatment of multiple sclerosis
MX2014014813A (es) Uso de agonistas o antagonistas inversos para el receptor de grelina para tratar trastornos del sueño.
TN2011000063A1 (en) Quinuclidine carbonate derivatives and medicinal composition thereof
WO2008066845A3 (en) Treatment of metabolic syndrome with norfluoxetine

Legal Events

Date Code Title Description
FG Grant or registration
GD Licence granted