MC1969A1 - Procedes pour preparer des composes antitumoraux,formulation pharmaceutique contenant ces composes,leurs utilisations en medecine et pharmacie,et composes intermediaires pour leur preparation - Google Patents

Procedes pour preparer des composes antitumoraux,formulation pharmaceutique contenant ces composes,leurs utilisations en medecine et pharmacie,et composes intermediaires pour leur preparation

Info

Publication number
MC1969A1
MC1969A1 MC882000A MC2000A MC1969A1 MC 1969 A1 MC1969 A1 MC 1969A1 MC 882000 A MC882000 A MC 882000A MC 2000 A MC2000 A MC 2000A MC 1969 A1 MC1969 A1 MC 1969A1
Authority
MC
Monaco
Prior art keywords
compounds
pharmacy
medicine
preparation
methods
Prior art date
Application number
MC882000A
Other languages
English (en)
French (fr)
Inventor
Teanby Hodgson Simon
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of MC1969A1 publication Critical patent/MC1969A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
MC882000A 1987-08-15 1988-08-11 Procedes pour preparer des composes antitumoraux,formulation pharmaceutique contenant ces composes,leurs utilisations en medecine et pharmacie,et composes intermediaires pour leur preparation MC1969A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878719368A GB8719368D0 (en) 1987-08-15 1987-08-15 Heterocyclic compounds

Publications (1)

Publication Number Publication Date
MC1969A1 true MC1969A1 (fr) 1989-09-29

Family

ID=10622364

Family Applications (1)

Application Number Title Priority Date Filing Date
MC882000A MC1969A1 (fr) 1987-08-15 1988-08-11 Procedes pour preparer des composes antitumoraux,formulation pharmaceutique contenant ces composes,leurs utilisations en medecine et pharmacie,et composes intermediaires pour leur preparation

Country Status (28)

Country Link
US (5) US5091531A (sh)
EP (1) EP0305093B1 (sh)
JP (1) JPS6468375A (sh)
KR (1) KR890003764A (sh)
CN (2) CN1031532A (sh)
AP (1) AP89A (sh)
AT (1) ATE103919T1 (sh)
AU (1) AU613392B2 (sh)
CA (1) CA1336432C (sh)
DD (1) DD289529A5 (sh)
DE (1) DE3888897T2 (sh)
DK (1) DK168954B1 (sh)
ES (1) ES2063039T3 (sh)
FI (1) FI89600C (sh)
GB (1) GB8719368D0 (sh)
HU (1) HU204052B (sh)
IL (1) IL87435A (sh)
MC (1) MC1969A1 (sh)
MX (1) MX12655A (sh)
MY (1) MY103602A (sh)
NO (1) NO168305C (sh)
NZ (1) NZ225808A (sh)
PH (1) PH25741A (sh)
PL (3) PL159008B1 (sh)
PT (1) PT88260B (sh)
RU (3) RU1769759C (sh)
YU (3) YU47200B (sh)
ZA (1) ZA885996B (sh)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8719368D0 (en) * 1987-08-15 1987-09-23 Wellcome Found Heterocyclic compounds
PH27291A (en) * 1989-01-31 1993-05-04 Takeda Chemical Industries Ltd Imidazolpyrimidazines their production and use
EP0440119A1 (en) * 1990-01-31 1991-08-07 Takeda Chemical Industries, Ltd. Imidazopyridazine compounds, their production and use
EP0444549B1 (en) * 1990-03-01 1995-01-25 Takeda Chemical Industries, Ltd. Imidazopyridazines their production and use
DE69913558T2 (de) * 1998-10-21 2004-11-04 Takeda Chemical Industries, Ltd. Kondensierte pyridazinderivate, verfahren zu ihrer herstellung und ihre anwendung
EP1307200A2 (en) 2000-06-30 2003-05-07 Wyeth Substituted-triazolopyrimidines as anticancer agents
JP3767352B2 (ja) 2000-09-18 2006-04-19 トヨタ自動車株式会社 内燃機関の制御装置
WO2002083675A2 (en) * 2001-04-10 2002-10-24 Merck Sharp & Dohme Limited Inhibitors of akt activity
MX2009001349A (es) * 2006-08-04 2009-04-17 Takeda Pharmaceutical Derivado heterociclico fusionado y su uso.
US7750007B2 (en) * 2006-11-06 2010-07-06 Supergen, Inc. Imidazo[1,2-beta]pyridazine and pyrazolo[1,5-alpha]pyrimidine derivatives and their use as protein kinase inhibitors
JP5463287B2 (ja) * 2007-08-17 2014-04-09 アイカジェン， インコーポレイテッド カリウムチャネル調節物質としての複素環
US8431608B2 (en) 2007-08-17 2013-04-30 Icagen Inc. Heterocycles as potassium channel modulators
MX2010009414A (es) * 2008-02-28 2010-09-24 Novartis Ag Derivados de imidazo-[1,2-b]-piridazina para el tratamiento de enfermedad mediada por cinasa de tirosina c-met.
EP2277881A4 (en) * 2008-04-18 2011-09-07 Shionogi & Co HETEROCYCLIC COMPOUND HAVING INHIBITORY ACTIVITY ON P13K
UY32049A (es) * 2008-08-14 2010-03-26 Takeda Pharmaceutical Inhibidores de cmet
TW201437211A (zh) * 2013-03-01 2014-10-01 Bayer Pharma AG 經取代咪唑并嗒□

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB305093A (en) * 1928-01-30 1929-07-25 British Continental Motors Ltd Improvements relating to induction passages of sleeve-valve internal combustion engines
US3809691A (en) * 1967-10-23 1974-05-07 Eastman Kodak Co Novel cyanine dyes with fused imidazolo nuclei
US3615639A (en) * 1967-10-23 1971-10-26 Eastman Kodak Co Direct positive silver halide emulsions containing dyes as electron acceptors and spectral sensitizers
DE2043811A1 (en) * 1970-09-03 1972-03-09 E.I. du Pont de Nemours and Co., Wilmington, Del. (V.StA.) Fungicidal and acaricidal alkyl 2-benzimi- - dazole carbomate derivs
US3725407A (en) * 1971-04-08 1973-04-03 American Cyanamid Co 6-substituted amino-3-nitroimidazo(1,2-b)pyridazines and methods of preparing the same
FR2315507A1 (fr) * 1975-06-26 1977-01-21 Roussel Uclaf Imidazo /1,2-b/ pyridazines substituees, procede de preparation et compositions pesticides les renfermant
US4105767A (en) * 1977-03-28 1978-08-08 Merck & Co., Inc. Imidazo [1,2-a] pyridines substituted with a thienyl, thiazolyl, or thiadiazolyl group
US4166851A (en) * 1977-05-16 1979-09-04 Merck & Co., Inc. Certain imidazo(1,2a)pyridine derivatives
US4154835A (en) * 1977-10-12 1979-05-15 Merck & Co., Inc. Anthelmintic imidazo [1,2-a] pyridines
US4330543A (en) * 1978-12-14 1982-05-18 Merck & Co., Inc. Imidazoazines and imidazodiazines
US4221796A (en) * 1979-09-19 1980-09-09 E. R. Squibb & Sons, Inc. Substituted imidazolo-pyridines and method
DE3131365A1 (de) * 1981-08-07 1983-02-24 Henkel KGaA, 4000 Düsseldorf Neue diglycidyl-substituierte heterocyclische verbindungen, verfahren zu ihrer herstellung und ihre verwendung in arzneimittelzubereitungen mit cytostatischer wirksamkeit
JPS58126887A (ja) * 1981-09-26 1983-07-28 Takeda Chem Ind Ltd 新規７−デアザプリン誘導体
US4460773A (en) * 1982-02-05 1984-07-17 Lion Corporation 1-Phenyl-1H-pyrazolo [3,4-b]pyrazine derivatives and process for preparing same
US4464372A (en) * 1982-08-16 1984-08-07 Schering Corporation Imidazo[1,2-b]pyridazines
IL69417A (en) * 1982-08-27 1987-12-20 Roussel Uclaf 2-acyl imidazo(1,2-a)pyrimidines,their preparation and pharmaceutical compositions containing them
US4654347A (en) * 1983-06-23 1987-03-31 American Cyanamid Company Aryl and heteroaryl[[7-(3-disubstituted amino)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]methanones
DE3401911A1 (de) * 1984-01-20 1985-08-01 A. Nattermann & Cie GmbH, 5000 Köln Substituierte 4,5-dihydro-6-vinyl-3(2h)-pyridazinone und 6-vinyl-3(2h)-pyridazinone sowie verfahren zu ihrer herstellung
DE3423092A1 (de) * 1984-06-22 1986-01-02 Dr. Karl Thomae Gmbh, 7950 Biberach Neue 8-alkylthio-2-piperazino-pyrimido(5,4-d) pyrimidine, ihre herstellung und diese verbindungen enthaltende arzneimittel
US4569934A (en) * 1984-10-09 1986-02-11 American Cyanamid Company Imidazo[1,2-b]pyridazines
DE3446812A1 (de) * 1984-12-21 1986-06-26 Dr. Karl Thomae Gmbh, 7950 Biberach Neue imidazoderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel
DE3446778A1 (de) * 1984-12-21 1986-07-03 Dr. Karl Thomae Gmbh, 7950 Biberach Neue imidazoderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel
DE3527036A1 (de) * 1985-07-27 1987-02-05 Merck Patent Gmbh 6-arylalkenylpyridazinone
DE3542661A1 (de) * 1985-12-03 1987-06-04 Bayer Ag Imidazopyridazinalkensaeureamide, verfahren zu ihrer herstellung, zwischenprodukte zu ihrer herstellung
WO1989001478A1 (en) * 1987-08-07 1989-02-23 The Australian National University ARYLOXY- AND ARALKYLTHIO-IMIDAZO[1,2-b]PYRIDAZINES
WO1989001333A1 (en) * 1987-08-07 1989-02-23 The Australian National University IMIDAZO[1,2-b]PYRIDAZINES
GB8719368D0 (en) * 1987-08-15 1987-09-23 Wellcome Found Heterocyclic compounds

Also Published As

Publication number Publication date
NO883613D0 (no) 1988-08-12
FI883758A (fi) 1989-02-16
NO883613L (no) 1989-02-16
FI89600C (fi) 1993-10-25
US5371219A (en) 1994-12-06
AU2097988A (en) 1989-02-16
FI89600B (fi) 1993-07-15
PL274216A1 (en) 1989-05-02
DD289529A5 (de) 1991-05-02
PT88260B (pt) 1995-03-01
NO168305C (no) 1992-02-05
IL87435A0 (en) 1989-01-31
YU47212B (sh) 1995-01-31
EP0305093B1 (en) 1994-04-06
US5447956A (en) 1995-09-05
HUT50473A (en) 1990-02-28
GB8719368D0 (en) 1987-09-23
PL159008B1 (pl) 1992-11-30
ATE103919T1 (de) 1994-04-15
ZA885996B (en) 1990-04-25
AP8800098A0 (en) 1988-08-01
PL160044B1 (pl) 1993-02-26
DE3888897D1 (de) 1994-05-11
AU613392B2 (en) 1991-08-01
EP0305093A1 (en) 1989-03-01
MY103602A (en) 1993-08-28
US5380759A (en) 1995-01-10
US5538970A (en) 1996-07-23
FI883758A0 (fi) 1988-08-12
YU47130B (sh) 1994-12-28
DK451588D0 (da) 1988-08-12
NO168305B (no) 1991-10-28
RU1836372C (ru) 1993-08-23
YU156988A (en) 1990-04-30
YU47200B (sh) 1995-01-31
AP89A (en) 1990-06-14
DE3888897T2 (de) 1994-10-20
CA1336432C (en) 1995-07-25
HU204052B (en) 1991-11-28
DK451588A (da) 1989-02-16
KR890003764A (ko) 1989-04-17
YU202889A (en) 1990-04-30
JPS6468375A (en) 1989-03-14
MX12655A (es) 1993-10-01
IL87435A (en) 1993-01-31
PH25741A (en) 1991-10-18
NZ225808A (en) 1991-07-26
US5091531A (en) 1992-02-25
DK168954B1 (da) 1994-07-18
ES2063039T3 (es) 1995-01-01
PT88260A (pt) 1989-09-14
RU1769759C (ru) 1992-10-15
YU202789A (en) 1990-04-30
PL160045B1 (en) 1993-02-26
CN1031532A (zh) 1989-03-08
RU2017741C1 (ru) 1994-08-15
CN1085901A (zh) 1994-04-27

Similar Documents

Publication Publication Date Title
MC1969A1 (fr) Procedes pour preparer des composes antitumoraux,formulation pharmaceutique contenant ces composes,leurs utilisations en medecine et pharmacie,et composes intermediaires pour leur preparation
DE3268533D1 (en) Inhalation drugs, methods for their production and pharmaceutical formulations containing them
IT1178193B (it) Perfezionamento nelle capsule divisibili per la somministrazione dosata di prodotti farmaceutici
PT77503A (en) Process for preparing pharmaceutical compositions for oral and/or enteral administration
IT8721668A0 (it) Insufflatore per la somministrazione di farmaci sottoforma di polvere predosata in opercoli.
AU627845B2 (en) Improvements in or relating to devices for administration of drugs or the like
ES8104720A1 (es) Un procedimiento para la preparacion de composiciones lipo- somicas de substancias activas grasosolubles
IL86877A (en) Carbazole derivatives,their preparation and pharmaceutical compositions containing them
MC2077A1 (fr) Derives benzoiques et phenylacetiques,procedes pour leur preparation et compositions pharmaceutiques en contenant
MA18829A1 (fr) Derives de la pyrimidine,procedes pour leur preparation,compositions pharmaceutiques contenant ces composes et leur utilisation therapeutique
LTIP915A (en) Catehol derivatives,methods for their preparation and pharmaceutical compositions containing them
IL85247A (en) Polyamine derivatives,process for their preparation and pharmaceutical compositions containing them
DE2966142D1 (en) Quinolein-3-carboxylic acid derivatives, process for their preparation, their use in medicines and pharmaceutical compositions containing them
FR2628425B1 (fr) Derives d'isoindolinone, leurs procedes de preparation et les medicaments les contenant
DE3787178D1 (de) Behälter zur Verabreichung eines Heilmittels in einem Zufuhrsystem.
DE3880667D1 (de) Ampulle zur gesteuerten verabreichung eines heilmittels.
GB2190677B (en) 1-(hydroxystyryl)-5h-2,3-benzodiazepine derivatives, process for the preparation thereof and pharmaceutical compositions containing the same
BE878028A (fr) Nouvelles imidazoquinoxalines et leurs sels, leur procede de preparation, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant
BE857289A (fr) 2-benzyl-pyrrolidines, procede pour leur preparation et medicaments contenant ces composes
BE874253A (fr) Nouvelles 2-phenylimino-imidazolidines substituees, leurs sels d'addition avec des acides, medicaments les renfermant et procedes pour leur preparation
FR2668148B1 (fr) Nouveau derive de 5h-benzodiazepine, compositions pharmaceutiques le contenant et procede pour les preparer.
IL88617A0 (en) Quinoline derivatives,the preparation thereof and pharmaceutical compositions containing them
GB2052980B (en) Pharmaceutical composition for oral administration comprising methoxsalen
FR2621918B1 (fr) 2',3'-didesoxy-4-thio-uridines, procede de preparation de ces substances et medicaments qui en contiennent
FR2675144B1 (fr) Nouvelles quinolones difluorees - leur procede de preparation et les compositions pharmaceutiques en renfermant.

Legal Events

Date Code Title Description
YP Annual fee paid