LU87432A1 - Sels de cephalosporine,melanges contenant ces sels et procede de preparation du sel d'addition d'acide sulfurique - Google Patents

Sels de cephalosporine,melanges contenant ces sels et procede de preparation du sel d'addition d'acide sulfurique Download PDF

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Publication number
LU87432A1
LU87432A1 LU87432A LU87432A LU87432A1 LU 87432 A1 LU87432 A1 LU 87432A1 LU 87432 A LU87432 A LU 87432A LU 87432 A LU87432 A LU 87432A LU 87432 A1 LU87432 A1 LU 87432A1
Authority
LU
Luxembourg
Prior art keywords
salt
salts
crystalline
mixture
methyl
Prior art date
Application number
LU87432A
Other languages
English (en)
French (fr)
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22510643&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LU87432(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of LU87432A1 publication Critical patent/LU87432A1/fr

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
LU87432A 1988-01-19 1989-01-18 Sels de cephalosporine,melanges contenant ces sels et procede de preparation du sel d'addition d'acide sulfurique LU87432A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14489988 1988-01-19
US07/144,899 US4910301A (en) 1985-08-05 1988-01-19 Cefepime cephalosporin salts

Publications (1)

Publication Number Publication Date
LU87432A1 true LU87432A1 (fr) 1989-08-30

Family

ID=22510643

Family Applications (1)

Application Number Title Priority Date Filing Date
LU87432A LU87432A1 (fr) 1988-01-19 1989-01-18 Sels de cephalosporine,melanges contenant ces sels et procede de preparation du sel d'addition d'acide sulfurique

Country Status (32)

Country Link
US (1) US4910301A (de)
JP (1) JPH0725768B2 (de)
KR (1) KR950003612B1 (de)
AT (1) AT399878B (de)
AU (1) AU615509B2 (de)
BE (1) BE1002749A5 (de)
CA (1) CA1298288C (de)
CY (1) CY1663A (de)
CZ (1) CZ281602B6 (de)
DD (2) DD283397A5 (de)
DE (1) DE3901359A1 (de)
DK (1) DK162054C (de)
EG (1) EG18749A (de)
ES (1) ES2012948A6 (de)
FI (1) FI86854C (de)
FR (1) FR2626003B1 (de)
GB (1) GB2213819B (de)
GR (1) GR1001218B (de)
HK (1) HK72292A (de)
HU (1) HU205940B (de)
IE (1) IE67447B1 (de)
IT (1) IT1229528B (de)
LU (1) LU87432A1 (de)
NL (1) NL192266C (de)
NZ (1) NZ227605A (de)
OA (1) OA09227A (de)
PT (1) PT89474B (de)
SE (1) SE505258C2 (de)
SG (1) SG75492G (de)
SK (1) SK281768B6 (de)
YU (1) YU221188A (de)
ZA (1) ZA89407B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5244891A (en) * 1985-08-05 1993-09-14 Bristol-Myers Squibb Company Injectable compositions of cefepime dihydrochloride hydrate
DE68917574T2 (de) * 1988-12-27 1994-12-15 Chugai Pharmaceutical Co Ltd Reinigungsverfahren für 1,2-Bis(nicotinamido)propan.
CA2011116C (en) * 1989-03-06 1999-11-16 Murray A. Kaplan Lyophilized bmy-28142 dihydrochloride for parenteral use
DE3919259A1 (de) * 1989-06-13 1990-12-20 Hoechst Ag Kristalline cephem-saeureadditionssalze und verfahren zu ihrer herstellung
US5698703A (en) * 1991-09-10 1997-12-16 Bristol-Myers Squibb Company Syn-isomer of thiazolyl intermediate and process for the preparation thereof
YU81692A (sh) * 1991-09-10 1995-03-27 Bristol-Myers Co. Postupak za proizvodnju cefalosporinskog antibiotika
US5594129A (en) * 1991-09-10 1997-01-14 Bristol-Myers Squibb Company Process for the preparation of a cephalosporin antibiotic
IL103110A (en) * 1991-09-10 1997-04-15 Bristol Myers Squibb Co Anhydrous process for preparing cefepime dihydrochloride hydrate
CA2099692C (en) * 1992-07-24 2003-09-30 Gary M. F. Lim Process for preparing cephalosporin intermediates
CA2101571A1 (en) * 1992-09-08 1994-03-09 Elizabeth A. Garofalo Crystalline dihydrate of a cephalosporin dihydrate salt and injectable compositions thereof
US5391729A (en) * 1992-09-08 1995-02-21 Bristol-Myers Squibb Company Crystalline dihydrate of a cephalosporin salt
US5401842A (en) * 1992-09-08 1995-03-28 Bristol-Myers Squibb Company Injectable compositions of a cephalosporin dihydrate salt
JPH0840907A (ja) 1994-08-03 1996-02-13 Meiji Seika Kaisha Ltd セファロスポリン注射剤
WO2005094800A2 (en) * 2004-03-31 2005-10-13 Lupin Ltd. A co-precipitated cefepime composition and process for preparation thereof
EP1773845A1 (de) * 2004-07-16 2007-04-18 Hetero Drugs Limited Verfahren zur herstellung reiner cephalosporinzwischenprodukte
ITMI20051684A1 (it) * 2005-09-13 2007-03-14 Harvest Lodge Ltd Procedimento per la produzione del dicloridrato di amminoacidi
ITMI20060422A1 (it) * 2006-03-09 2007-09-10 Harvest Lodge Ltd Procedimento diretto per la produzione del dicloridrato di un amminoacido
US8151846B2 (en) * 2006-12-15 2012-04-10 Center Line Wheel Corporation Wheel having inner bead-lock
TWI400243B (zh) * 2009-07-20 2013-07-01 Intervet Int Bv 製造西喹諾(cefquinome)粒子的方法
CN103304580B (zh) * 2013-06-09 2014-07-09 四川省惠达药业有限公司 一种盐酸头孢吡肟化合物、其制备方法及其药物组合物
CN108463461B (zh) * 2015-12-10 2021-11-19 奈加-Rgm制药有限公司 头孢烯化合物、其制备和用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4029655A (en) * 1975-04-11 1977-06-14 Eli Lilly And Company Method of preparing stable sterile crystalline cephalosporins for parenteral administration
JPS55151588A (en) * 1979-05-14 1980-11-26 Takeda Chem Ind Ltd Preparation of cephalosporin salt crystal
CH654010A5 (de) * 1979-05-25 1986-01-31 Glaxo Group Ltd Zwischenprodukte zur verwendung bei der herstellung von cephalosporin-antibiotika.
US4329453A (en) * 1979-10-02 1982-05-11 Glaxo Group Limited Cephalosporin antibiotic
CA1213882A (en) * 1982-03-04 1986-11-12 Jun Okumura Cephalosporins
US4406899A (en) * 1982-03-04 1983-09-27 Bristol-Myers Company Cephalosporins
US4525473A (en) * 1983-03-30 1985-06-25 Bristol-Myers Company Cephalosporins
US4537959A (en) * 1984-03-26 1985-08-27 Eli Lilly And Company Crystalline cephalosporin antibiotic salt
US4751295A (en) * 1984-04-09 1988-06-14 Bristol-Myers Company Cephalosporin derivatives
US4749694A (en) * 1984-04-26 1988-06-07 Merck & Co., Inc. Novel lysine esters used as absorption
FR2585705B1 (fr) * 1985-08-05 1989-01-13 Bristol Myers Co Sels de cephalosporine et compositions injectables
US4808617A (en) * 1985-12-18 1989-02-28 Bristol-Myers Company Lyophilized or precipitated cephalosporin zwitterion and salt combination
US4791196A (en) * 1986-09-26 1988-12-13 Sankyo Company Limited Crystalline cephem carboxylic acid addition salt

Also Published As

Publication number Publication date
YU221188A (en) 1990-04-30
NL192266C (nl) 1997-04-03
HU205940B (en) 1992-07-28
OA09227A (fr) 1992-06-30
PT89474B (pt) 1993-12-31
EG18749A (en) 1993-12-30
GB2213819B (en) 1991-11-27
JPH029885A (ja) 1990-01-12
SG75492G (en) 1992-10-02
DD284807A5 (de) 1990-11-28
CA1298288C (en) 1992-03-31
DK20789D0 (da) 1989-01-18
SK24389A3 (en) 2000-12-11
DK20789A (da) 1989-07-20
FR2626003A1 (fr) 1989-07-21
AU2862389A (en) 1989-07-20
IT8947539A0 (it) 1988-01-17
US4910301A (en) 1990-03-20
FI86854C (fi) 1992-10-26
IT1229528B (it) 1991-09-04
NZ227605A (en) 1991-06-25
DK162054C (da) 1992-02-10
GB8901073D0 (en) 1989-03-15
FI86854B (fi) 1992-07-15
PT89474A (pt) 1990-02-08
IE67447B1 (en) 1996-04-03
SE8900173D0 (sv) 1989-01-18
GB2213819A (en) 1989-08-23
GR1001218B (el) 1993-06-21
SE8900173L (en) 1989-01-18
CZ281602B6 (cs) 1996-11-13
ATA8589A (de) 1994-12-15
HUT50347A (en) 1990-01-29
AT399878B (de) 1995-08-25
HK72292A (en) 1992-10-02
DK162054B (da) 1991-09-09
ZA89407B (en) 1989-09-27
AU615509B2 (en) 1991-10-03
IE890144L (en) 1989-07-19
CZ24389A3 (en) 1996-08-14
FR2626003B1 (fr) 1992-10-16
SK281768B6 (sk) 2001-07-10
SE505258C2 (sv) 1997-07-21
KR890011895A (ko) 1989-08-23
CY1663A (en) 1993-05-14
NL8900111A (nl) 1989-08-16
ES2012948A6 (es) 1990-04-16
DD283397A5 (de) 1990-10-10
BE1002749A5 (fr) 1991-05-28
DE3901359A1 (de) 1989-10-05
JPH0725768B2 (ja) 1995-03-22
NL192266B (nl) 1996-12-02
FI890213A (fi) 1989-07-20
FI890213A0 (fi) 1989-01-16
DE3901359C2 (de) 1992-04-30
KR950003612B1 (ko) 1995-04-17

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