YU221188A - Process for obtaining crystall acidic additional salts of cephalosporine - Google Patents

Process for obtaining crystall acidic additional salts of cephalosporine

Info

Publication number
YU221188A
YU221188A YU02211/88A YU221188A YU221188A YU 221188 A YU221188 A YU 221188A YU 02211/88 A YU02211/88 A YU 02211/88A YU 221188 A YU221188 A YU 221188A YU 221188 A YU221188 A YU 221188A
Authority
YU
Yugoslavia
Prior art keywords
cephalosporine
crystall
obtaining
salts
additional salts
Prior art date
Application number
YU02211/88A
Other languages
English (en)
Inventor
K A Murray
W T Hudyma
A R Lipper
M K Shin
D S Boettger
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22510643&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=YU221188(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of YU221188A publication Critical patent/YU221188A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
YU02211/88A 1988-01-19 1988-12-06 Process for obtaining crystall acidic additional salts of cephalosporine YU221188A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/144,899 US4910301A (en) 1985-08-05 1988-01-19 Cefepime cephalosporin salts

Publications (1)

Publication Number Publication Date
YU221188A true YU221188A (en) 1990-04-30

Family

ID=22510643

Family Applications (1)

Application Number Title Priority Date Filing Date
YU02211/88A YU221188A (en) 1988-01-19 1988-12-06 Process for obtaining crystall acidic additional salts of cephalosporine

Country Status (32)

Country Link
US (1) US4910301A (xx)
JP (1) JPH0725768B2 (xx)
KR (1) KR950003612B1 (xx)
AT (1) AT399878B (xx)
AU (1) AU615509B2 (xx)
BE (1) BE1002749A5 (xx)
CA (1) CA1298288C (xx)
CY (1) CY1663A (xx)
CZ (1) CZ281602B6 (xx)
DD (2) DD284807A5 (xx)
DE (1) DE3901359A1 (xx)
DK (1) DK162054C (xx)
EG (1) EG18749A (xx)
ES (1) ES2012948A6 (xx)
FI (1) FI86854C (xx)
FR (1) FR2626003B1 (xx)
GB (1) GB2213819B (xx)
GR (1) GR1001218B (xx)
HK (1) HK72292A (xx)
HU (1) HU205940B (xx)
IE (1) IE67447B1 (xx)
IT (1) IT1229528B (xx)
LU (1) LU87432A1 (xx)
NL (1) NL192266C (xx)
NZ (1) NZ227605A (xx)
OA (1) OA09227A (xx)
PT (1) PT89474B (xx)
SE (1) SE505258C2 (xx)
SG (1) SG75492G (xx)
SK (1) SK281768B6 (xx)
YU (1) YU221188A (xx)
ZA (1) ZA89407B (xx)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5244891A (en) * 1985-08-05 1993-09-14 Bristol-Myers Squibb Company Injectable compositions of cefepime dihydrochloride hydrate
EP0376185B1 (en) * 1988-12-27 1994-08-17 Chugai Seiyaku Kabushiki Kaisha Process for purification of 1,2-bis(nicotinamido)propane
CA2011116C (en) * 1989-03-06 1999-11-16 Murray A. Kaplan Lyophilized bmy-28142 dihydrochloride for parenteral use
DE3919259A1 (de) * 1989-06-13 1990-12-20 Hoechst Ag Kristalline cephem-saeureadditionssalze und verfahren zu ihrer herstellung
US5698703A (en) * 1991-09-10 1997-12-16 Bristol-Myers Squibb Company Syn-isomer of thiazolyl intermediate and process for the preparation thereof
IL103110A (en) * 1991-09-10 1997-04-15 Bristol Myers Squibb Co Anhydrous process for preparing cefepime dihydrochloride hydrate
YU81692A (sh) * 1991-09-10 1995-03-27 Bristol-Myers Co. Postupak za proizvodnju cefalosporinskog antibiotika
US5594129A (en) * 1991-09-10 1997-01-14 Bristol-Myers Squibb Company Process for the preparation of a cephalosporin antibiotic
CA2099692C (en) * 1992-07-24 2003-09-30 Gary M. F. Lim Process for preparing cephalosporin intermediates
US5391729A (en) * 1992-09-08 1995-02-21 Bristol-Myers Squibb Company Crystalline dihydrate of a cephalosporin salt
US5401842A (en) * 1992-09-08 1995-03-28 Bristol-Myers Squibb Company Injectable compositions of a cephalosporin dihydrate salt
CA2101571A1 (en) * 1992-09-08 1994-03-09 Elizabeth A. Garofalo Crystalline dihydrate of a cephalosporin dihydrate salt and injectable compositions thereof
JPH0840907A (ja) 1994-08-03 1996-02-13 Meiji Seika Kaisha Ltd セファロスポリン注射剤
WO2005094800A2 (en) * 2004-03-31 2005-10-13 Lupin Ltd. A co-precipitated cefepime composition and process for preparation thereof
US20070111980A1 (en) * 2004-07-16 2007-05-17 Bandi Parthasaradhi Reddy Process for preparing pure cephalosporine intermediates
ITMI20051684A1 (it) * 2005-09-13 2007-03-14 Harvest Lodge Ltd Procedimento per la produzione del dicloridrato di amminoacidi
ITMI20060422A1 (it) * 2006-03-09 2007-09-10 Harvest Lodge Ltd Procedimento diretto per la produzione del dicloridrato di un amminoacido
US8151846B2 (en) * 2006-12-15 2012-04-10 Center Line Wheel Corporation Wheel having inner bead-lock
AR077320A1 (es) * 2009-07-20 2011-08-17 Intervet Int Bv Metodo para la preparacion de particulas de cefquinoma y formulaciones farmaceuticas que las comprenden.
CN103304580B (zh) * 2013-06-09 2014-07-09 四川省惠达药业有限公司 一种盐酸头孢吡肟化合物、其制备方法及其药物组合物
WO2017096472A1 (en) * 2015-12-10 2017-06-15 Naeja-Rgm Pharmaceuticals Inc. Cephem compounds, their production and use

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4029655A (en) * 1975-04-11 1977-06-14 Eli Lilly And Company Method of preparing stable sterile crystalline cephalosporins for parenteral administration
JPS55151588A (en) * 1979-05-14 1980-11-26 Takeda Chem Ind Ltd Preparation of cephalosporin salt crystal
IT1145686B (it) * 1979-05-25 1986-11-05 Glaxo Group Ltd Intermedi per la preparazione di antibiotici cefalosporinici e procedimento per prepararli
US4329453A (en) * 1979-10-02 1982-05-11 Glaxo Group Limited Cephalosporin antibiotic
US4406899A (en) * 1982-03-04 1983-09-27 Bristol-Myers Company Cephalosporins
CA1213882A (en) * 1982-03-04 1986-11-12 Jun Okumura Cephalosporins
US4525473A (en) * 1983-03-30 1985-06-25 Bristol-Myers Company Cephalosporins
US4537959A (en) * 1984-03-26 1985-08-27 Eli Lilly And Company Crystalline cephalosporin antibiotic salt
US4751295A (en) * 1984-04-09 1988-06-14 Bristol-Myers Company Cephalosporin derivatives
US4749694A (en) * 1984-04-26 1988-06-07 Merck & Co., Inc. Novel lysine esters used as absorption
FR2585705B1 (fr) * 1985-08-05 1989-01-13 Bristol Myers Co Sels de cephalosporine et compositions injectables
US4808617A (en) * 1985-12-18 1989-02-28 Bristol-Myers Company Lyophilized or precipitated cephalosporin zwitterion and salt combination
US4791196A (en) * 1986-09-26 1988-12-13 Sankyo Company Limited Crystalline cephem carboxylic acid addition salt

Also Published As

Publication number Publication date
SE505258C2 (sv) 1997-07-21
GB8901073D0 (en) 1989-03-15
HUT50347A (en) 1990-01-29
OA09227A (fr) 1992-06-30
DK20789A (da) 1989-07-20
LU87432A1 (fr) 1989-08-30
FI86854C (fi) 1992-10-26
PT89474B (pt) 1993-12-31
CY1663A (en) 1993-05-14
JPH0725768B2 (ja) 1995-03-22
NZ227605A (en) 1991-06-25
EG18749A (en) 1993-12-30
SK24389A3 (en) 2000-12-11
ATA8589A (de) 1994-12-15
GR1001218B (el) 1993-06-21
AU2862389A (en) 1989-07-20
CZ24389A3 (en) 1996-08-14
US4910301A (en) 1990-03-20
DK20789D0 (da) 1989-01-18
IT8947539A0 (it) 1988-01-17
ZA89407B (en) 1989-09-27
ES2012948A6 (es) 1990-04-16
DK162054C (da) 1992-02-10
IT1229528B (it) 1991-09-04
KR890011895A (ko) 1989-08-23
CA1298288C (en) 1992-03-31
DD284807A5 (de) 1990-11-28
IE890144L (en) 1989-07-19
SE8900173D0 (sv) 1989-01-18
SK281768B6 (sk) 2001-07-10
GB2213819A (en) 1989-08-23
GB2213819B (en) 1991-11-27
BE1002749A5 (fr) 1991-05-28
DD283397A5 (de) 1990-10-10
FI890213A (fi) 1989-07-20
FR2626003B1 (fr) 1992-10-16
HU205940B (en) 1992-07-28
JPH029885A (ja) 1990-01-12
DE3901359A1 (de) 1989-10-05
NL192266B (nl) 1996-12-02
FR2626003A1 (fr) 1989-07-21
IE67447B1 (en) 1996-04-03
FI86854B (fi) 1992-07-15
SE8900173L (en) 1989-01-18
HK72292A (en) 1992-10-02
NL8900111A (nl) 1989-08-16
CZ281602B6 (cs) 1996-11-13
FI890213A0 (fi) 1989-01-16
AT399878B (de) 1995-08-25
AU615509B2 (en) 1991-10-03
DK162054B (da) 1991-09-09
SG75492G (en) 1992-10-02
DE3901359C2 (xx) 1992-04-30
KR950003612B1 (ko) 1995-04-17
NL192266C (nl) 1997-04-03
PT89474A (pt) 1990-02-08

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