OA09227A - "Sels de céphalosporine, mélanges contenant ces sels et procédé de préparation du sel d'addition d'acide sulfurique". - Google Patents

"Sels de céphalosporine, mélanges contenant ces sels et procédé de préparation du sel d'addition d'acide sulfurique".

Info

Publication number
OA09227A
OA09227A OA59509A OA59509A OA09227A OA 09227 A OA09227 A OA 09227A OA 59509 A OA59509 A OA 59509A OA 59509 A OA59509 A OA 59509A OA 09227 A OA09227 A OA 09227A
Authority
OA
OAPI
Prior art keywords
salts
preparing
sulfuric acid
acid addition
addition salt
Prior art date
Application number
OA59509A
Other languages
English (en)
French (fr)
Inventor
Kaplan Murray Arthur
Thomas W Hudyma
Lipper Robert Alan
Shih Kun Mao
Susan D Boettger
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22510643&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=OA09227(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of OA09227A publication Critical patent/OA09227A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
OA59509A 1988-01-19 1989-01-18 "Sels de céphalosporine, mélanges contenant ces sels et procédé de préparation du sel d'addition d'acide sulfurique". OA09227A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/144,899 US4910301A (en) 1985-08-05 1988-01-19 Cefepime cephalosporin salts

Publications (1)

Publication Number Publication Date
OA09227A true OA09227A (fr) 1992-06-30

Family

ID=22510643

Family Applications (1)

Application Number Title Priority Date Filing Date
OA59509A OA09227A (fr) 1988-01-19 1989-01-18 "Sels de céphalosporine, mélanges contenant ces sels et procédé de préparation du sel d'addition d'acide sulfurique".

Country Status (32)

Country Link
US (1) US4910301A (xx)
JP (1) JPH0725768B2 (xx)
KR (1) KR950003612B1 (xx)
AT (1) AT399878B (xx)
AU (1) AU615509B2 (xx)
BE (1) BE1002749A5 (xx)
CA (1) CA1298288C (xx)
CY (1) CY1663A (xx)
CZ (1) CZ281602B6 (xx)
DD (2) DD284807A5 (xx)
DE (1) DE3901359A1 (xx)
DK (1) DK162054C (xx)
EG (1) EG18749A (xx)
ES (1) ES2012948A6 (xx)
FI (1) FI86854C (xx)
FR (1) FR2626003B1 (xx)
GB (1) GB2213819B (xx)
GR (1) GR1001218B (xx)
HK (1) HK72292A (xx)
HU (1) HU205940B (xx)
IE (1) IE67447B1 (xx)
IT (1) IT1229528B (xx)
LU (1) LU87432A1 (xx)
NL (1) NL192266C (xx)
NZ (1) NZ227605A (xx)
OA (1) OA09227A (xx)
PT (1) PT89474B (xx)
SE (1) SE505258C2 (xx)
SG (1) SG75492G (xx)
SK (1) SK281768B6 (xx)
YU (1) YU221188A (xx)
ZA (1) ZA89407B (xx)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5244891A (en) * 1985-08-05 1993-09-14 Bristol-Myers Squibb Company Injectable compositions of cefepime dihydrochloride hydrate
EP0376185B1 (en) * 1988-12-27 1994-08-17 Chugai Seiyaku Kabushiki Kaisha Process for purification of 1,2-bis(nicotinamido)propane
CA2011116C (en) * 1989-03-06 1999-11-16 Murray A. Kaplan Lyophilized bmy-28142 dihydrochloride for parenteral use
DE3919259A1 (de) * 1989-06-13 1990-12-20 Hoechst Ag Kristalline cephem-saeureadditionssalze und verfahren zu ihrer herstellung
US5698703A (en) * 1991-09-10 1997-12-16 Bristol-Myers Squibb Company Syn-isomer of thiazolyl intermediate and process for the preparation thereof
IL103110A (en) * 1991-09-10 1997-04-15 Bristol Myers Squibb Co Anhydrous process for preparing cefepime dihydrochloride hydrate
YU81692A (sh) * 1991-09-10 1995-03-27 Bristol-Myers Co. Postupak za proizvodnju cefalosporinskog antibiotika
US5594129A (en) * 1991-09-10 1997-01-14 Bristol-Myers Squibb Company Process for the preparation of a cephalosporin antibiotic
CA2099692C (en) * 1992-07-24 2003-09-30 Gary M. F. Lim Process for preparing cephalosporin intermediates
US5391729A (en) * 1992-09-08 1995-02-21 Bristol-Myers Squibb Company Crystalline dihydrate of a cephalosporin salt
US5401842A (en) * 1992-09-08 1995-03-28 Bristol-Myers Squibb Company Injectable compositions of a cephalosporin dihydrate salt
CA2101571A1 (en) * 1992-09-08 1994-03-09 Elizabeth A. Garofalo Crystalline dihydrate of a cephalosporin dihydrate salt and injectable compositions thereof
JPH0840907A (ja) 1994-08-03 1996-02-13 Meiji Seika Kaisha Ltd セファロスポリン注射剤
WO2005094800A2 (en) * 2004-03-31 2005-10-13 Lupin Ltd. A co-precipitated cefepime composition and process for preparation thereof
US20070111980A1 (en) * 2004-07-16 2007-05-17 Bandi Parthasaradhi Reddy Process for preparing pure cephalosporine intermediates
ITMI20051684A1 (it) * 2005-09-13 2007-03-14 Harvest Lodge Ltd Procedimento per la produzione del dicloridrato di amminoacidi
ITMI20060422A1 (it) * 2006-03-09 2007-09-10 Harvest Lodge Ltd Procedimento diretto per la produzione del dicloridrato di un amminoacido
US8151846B2 (en) * 2006-12-15 2012-04-10 Center Line Wheel Corporation Wheel having inner bead-lock
AR077320A1 (es) * 2009-07-20 2011-08-17 Intervet Int Bv Metodo para la preparacion de particulas de cefquinoma y formulaciones farmaceuticas que las comprenden.
CN103304580B (zh) * 2013-06-09 2014-07-09 四川省惠达药业有限公司 一种盐酸头孢吡肟化合物、其制备方法及其药物组合物
WO2017096472A1 (en) * 2015-12-10 2017-06-15 Naeja-Rgm Pharmaceuticals Inc. Cephem compounds, their production and use

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4029655A (en) * 1975-04-11 1977-06-14 Eli Lilly And Company Method of preparing stable sterile crystalline cephalosporins for parenteral administration
JPS55151588A (en) * 1979-05-14 1980-11-26 Takeda Chem Ind Ltd Preparation of cephalosporin salt crystal
IT1145686B (it) * 1979-05-25 1986-11-05 Glaxo Group Ltd Intermedi per la preparazione di antibiotici cefalosporinici e procedimento per prepararli
US4329453A (en) * 1979-10-02 1982-05-11 Glaxo Group Limited Cephalosporin antibiotic
US4406899A (en) * 1982-03-04 1983-09-27 Bristol-Myers Company Cephalosporins
CA1213882A (en) * 1982-03-04 1986-11-12 Jun Okumura Cephalosporins
US4525473A (en) * 1983-03-30 1985-06-25 Bristol-Myers Company Cephalosporins
US4537959A (en) * 1984-03-26 1985-08-27 Eli Lilly And Company Crystalline cephalosporin antibiotic salt
US4751295A (en) * 1984-04-09 1988-06-14 Bristol-Myers Company Cephalosporin derivatives
US4749694A (en) * 1984-04-26 1988-06-07 Merck & Co., Inc. Novel lysine esters used as absorption
FR2585705B1 (fr) * 1985-08-05 1989-01-13 Bristol Myers Co Sels de cephalosporine et compositions injectables
US4808617A (en) * 1985-12-18 1989-02-28 Bristol-Myers Company Lyophilized or precipitated cephalosporin zwitterion and salt combination
US4791196A (en) * 1986-09-26 1988-12-13 Sankyo Company Limited Crystalline cephem carboxylic acid addition salt

Also Published As

Publication number Publication date
SE505258C2 (sv) 1997-07-21
GB8901073D0 (en) 1989-03-15
HUT50347A (en) 1990-01-29
DK20789A (da) 1989-07-20
LU87432A1 (fr) 1989-08-30
FI86854C (fi) 1992-10-26
PT89474B (pt) 1993-12-31
CY1663A (en) 1993-05-14
JPH0725768B2 (ja) 1995-03-22
NZ227605A (en) 1991-06-25
EG18749A (en) 1993-12-30
SK24389A3 (en) 2000-12-11
ATA8589A (de) 1994-12-15
GR1001218B (el) 1993-06-21
AU2862389A (en) 1989-07-20
CZ24389A3 (en) 1996-08-14
US4910301A (en) 1990-03-20
DK20789D0 (da) 1989-01-18
IT8947539A0 (it) 1988-01-17
ZA89407B (en) 1989-09-27
ES2012948A6 (es) 1990-04-16
DK162054C (da) 1992-02-10
IT1229528B (it) 1991-09-04
KR890011895A (ko) 1989-08-23
CA1298288C (en) 1992-03-31
DD284807A5 (de) 1990-11-28
IE890144L (en) 1989-07-19
SE8900173D0 (sv) 1989-01-18
YU221188A (en) 1990-04-30
SK281768B6 (sk) 2001-07-10
GB2213819A (en) 1989-08-23
GB2213819B (en) 1991-11-27
BE1002749A5 (fr) 1991-05-28
DD283397A5 (de) 1990-10-10
FI890213A (fi) 1989-07-20
FR2626003B1 (fr) 1992-10-16
HU205940B (en) 1992-07-28
JPH029885A (ja) 1990-01-12
DE3901359A1 (de) 1989-10-05
NL192266B (nl) 1996-12-02
FR2626003A1 (fr) 1989-07-21
IE67447B1 (en) 1996-04-03
FI86854B (fi) 1992-07-15
SE8900173L (en) 1989-01-18
HK72292A (en) 1992-10-02
NL8900111A (nl) 1989-08-16
CZ281602B6 (cs) 1996-11-13
FI890213A0 (fi) 1989-01-16
AT399878B (de) 1995-08-25
AU615509B2 (en) 1991-10-03
DK162054B (da) 1991-09-09
SG75492G (en) 1992-10-02
DE3901359C2 (xx) 1992-04-30
KR950003612B1 (ko) 1995-04-17
NL192266C (nl) 1997-04-03
PT89474A (pt) 1990-02-08

Similar Documents

Publication Publication Date Title
OA09227A (fr) "Sels de céphalosporine, mélanges contenant ces sels et procédé de préparation du sel d'addition d'acide sulfurique".
MA19639A1 (fr) Procede de preparation de derives de l'acide cis, endo-2-azabicyclo- (3,3,0) -octane-3- carboxylique et d'agents contenant ces derives
RO76614A (ro) Procedeu de preparare a unor derivati de 3,4dehidroprolina si deaacid4,5-dehidropipecelic
FR2595089B1 (fr) Procede de purification d'un sel de baryum
MA19990A1 (fr) Procede de preparation de sels cristallises d'addition avec des acides du cepheme
RO86257A (ro) Procedeu pentru prepararea de acid d-lactic
MA21413A1 (fr) Nouveau procede de preparation d'alcoxy-guanine
FI871087A (fi) Menetelmä terapeuttisesti aktiivisten 1,2,3,4-tetrahydro-3-karbamoyyli-2-tiokso/okso-5-pyrimidiinikarboksyylihappojohdannaisten valmistamiseksi
FR2688506B1 (fr) Procede de preparation de sels de l'acide clavulanique.
DZ2024A1 (fr) Préparation de sels d'acide clavulanique.
BE891492A (fr) Procede de cristallisation continue de monohydrate d'alpha-dextrose sous agitation energique
BE850523A (fr) Procede de preparation de sels d'acide 3,3-dimethyl-2-oxobutyrique
FI890477A0 (fi) Menetelmä terapeuttisesti käyttökelpoisen 2,5-diamino-6-fluoriheksaanihapon ja sen suolojen valmistamiseksi
MC1492A1 (fr) Sel d'ammonium d'un acide carboxylide substitue,procede de fabrication de ces sels,utilisation de ces sels et des preparations pharmaceutiques les contenant
RO90109A (ro) Procedeu de preparare a unor saruri de alchilsulfoniu ale n-fosfonometilglicinei
FR2626884B1 (fr) Procede de preparation de n-phosphonomethyl-imino-diacetique et de chlorure d'acide en resultant
FR2619098B1 (fr) Procede de purification de saumures concentrees d'halogenures alcalins
FR2633273B1 (fr) Procede de preparation de tetraflurorure d'uranium
FR2601939B1 (fr) Procede pour la preparation d'acide borique pur
FR2564093B1 (fr) Procede pour la preparation d'adenosine3', 5'-monophosphate cyclique n6-substitue ou des sels correspondants
FR2583419B1 (fr) Procede pour la preparation de 2-bromo-a-ergocryptine et ses sels d'addition d'acides.
FR2536899B1 (fr) Procede pour la denitrification de solutions residuaires aqueuses d'acide nitrique contenant des sels
MA20777A1 (fr) Procede pour la preparation de ranitidine ou des sels d'addition d'acides des memes
DZ2456A1 (fr) Procédé de préparation de sels de l'acide clavulanique.
FR2541993B1 (fr) Procede de preparation d'acide adipique