OA09227A - "Sels de céphalosporine, mélanges contenant ces sels et procédé de préparation du sel d'addition d'acide sulfurique". - Google Patents

"Sels de céphalosporine, mélanges contenant ces sels et procédé de préparation du sel d'addition d'acide sulfurique".

Info

Publication number
OA09227A
OA09227A OA59509A OA59509A OA09227A OA 09227 A OA09227 A OA 09227A OA 59509 A OA59509 A OA 59509A OA 59509 A OA59509 A OA 59509A OA 09227 A OA09227 A OA 09227A
Authority
OA
OAPI
Prior art keywords
salts
preparing
sulfuric acid
acid addition
addition salt
Prior art date
Application number
OA59509A
Other languages
English (en)
Inventor
Kaplan Murray Arthur
Thomas W Hudyma
Lipper Robert Alan
Shih Kun Mao
Susan D Boettger
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22510643&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=OA09227(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of OA09227A publication Critical patent/OA09227A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
OA59509A 1988-01-19 1989-01-18 "Sels de céphalosporine, mélanges contenant ces sels et procédé de préparation du sel d'addition d'acide sulfurique". OA09227A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/144,899 US4910301A (en) 1985-08-05 1988-01-19 Cefepime cephalosporin salts

Publications (1)

Publication Number Publication Date
OA09227A true OA09227A (fr) 1992-06-30

Family

ID=22510643

Family Applications (1)

Application Number Title Priority Date Filing Date
OA59509A OA09227A (fr) 1988-01-19 1989-01-18 "Sels de céphalosporine, mélanges contenant ces sels et procédé de préparation du sel d'addition d'acide sulfurique".

Country Status (32)

Country Link
US (1) US4910301A (fr)
JP (1) JPH0725768B2 (fr)
KR (1) KR950003612B1 (fr)
AT (1) AT399878B (fr)
AU (1) AU615509B2 (fr)
BE (1) BE1002749A5 (fr)
CA (1) CA1298288C (fr)
CY (1) CY1663A (fr)
CZ (1) CZ281602B6 (fr)
DD (2) DD283397A5 (fr)
DE (1) DE3901359A1 (fr)
DK (1) DK162054C (fr)
EG (1) EG18749A (fr)
ES (1) ES2012948A6 (fr)
FI (1) FI86854C (fr)
FR (1) FR2626003B1 (fr)
GB (1) GB2213819B (fr)
GR (1) GR1001218B (fr)
HK (1) HK72292A (fr)
HU (1) HU205940B (fr)
IE (1) IE67447B1 (fr)
IT (1) IT1229528B (fr)
LU (1) LU87432A1 (fr)
NL (1) NL192266C (fr)
NZ (1) NZ227605A (fr)
OA (1) OA09227A (fr)
PT (1) PT89474B (fr)
SE (1) SE505258C2 (fr)
SG (1) SG75492G (fr)
SK (1) SK281768B6 (fr)
YU (1) YU221188A (fr)
ZA (1) ZA89407B (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5244891A (en) * 1985-08-05 1993-09-14 Bristol-Myers Squibb Company Injectable compositions of cefepime dihydrochloride hydrate
DE68917574T2 (de) * 1988-12-27 1994-12-15 Chugai Pharmaceutical Co Ltd Reinigungsverfahren für 1,2-Bis(nicotinamido)propan.
CA2011116C (fr) * 1989-03-06 1999-11-16 Murray A. Kaplan Dihydrochlorure de bmy-28142 lyophilise pour usage parenteral
DE3919259A1 (de) * 1989-06-13 1990-12-20 Hoechst Ag Kristalline cephem-saeureadditionssalze und verfahren zu ihrer herstellung
MY108872A (en) * 1991-09-10 1996-11-30 Bristol Myers Squibb Co Preparation of a cephalosporin antibiotic using the syn-isomer of a thiazolyl intermediate.
US5594129A (en) * 1991-09-10 1997-01-14 Bristol-Myers Squibb Company Process for the preparation of a cephalosporin antibiotic
YU81692A (sh) * 1991-09-10 1995-03-27 Bristol-Myers Co. Postupak za proizvodnju cefalosporinskog antibiotika
US5698703A (en) * 1991-09-10 1997-12-16 Bristol-Myers Squibb Company Syn-isomer of thiazolyl intermediate and process for the preparation thereof
CA2099692C (fr) * 1992-07-24 2003-09-30 Gary M. F. Lim Procede de preparation d'intermediaires de la cephalosporine
US5401842A (en) * 1992-09-08 1995-03-28 Bristol-Myers Squibb Company Injectable compositions of a cephalosporin dihydrate salt
CA2101571A1 (fr) * 1992-09-08 1994-03-09 Elizabeth A. Garofalo Dihydrate cristallise d'un sel de cephalosporine dihydrate; compositions injectables a base de ce compose
US5391729A (en) * 1992-09-08 1995-02-21 Bristol-Myers Squibb Company Crystalline dihydrate of a cephalosporin salt
JPH0840907A (ja) 1994-08-03 1996-02-13 Meiji Seika Kaisha Ltd セファロスポリン注射剤
WO2005094800A2 (fr) * 2004-03-31 2005-10-13 Lupin Ltd. Composition de cefepime co-precipite et procede de preparation correspondant
WO2006008749A1 (fr) * 2004-07-16 2006-01-26 Hetero Drugs Limited Procede de preparation d'intermediaires de cephalosporine pures
ITMI20051684A1 (it) * 2005-09-13 2007-03-14 Harvest Lodge Ltd Procedimento per la produzione del dicloridrato di amminoacidi
ITMI20060422A1 (it) * 2006-03-09 2007-09-10 Harvest Lodge Ltd Procedimento diretto per la produzione del dicloridrato di un amminoacido
US8151846B2 (en) * 2006-12-15 2012-04-10 Center Line Wheel Corporation Wheel having inner bead-lock
AR077320A1 (es) * 2009-07-20 2011-08-17 Intervet Int Bv Metodo para la preparacion de particulas de cefquinoma y formulaciones farmaceuticas que las comprenden.
CN103304580B (zh) * 2013-06-09 2014-07-09 四川省惠达药业有限公司 一种盐酸头孢吡肟化合物、其制备方法及其药物组合物
AU2016367284C1 (en) * 2015-12-10 2018-09-20 Naeja-Rgm Pharmaceuticals Ulc Cephem compounds, their production and use

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4029655A (en) * 1975-04-11 1977-06-14 Eli Lilly And Company Method of preparing stable sterile crystalline cephalosporins for parenteral administration
JPS55151588A (en) * 1979-05-14 1980-11-26 Takeda Chem Ind Ltd Preparation of cephalosporin salt crystal
GB2052490B (en) * 1979-05-25 1983-09-07 Glaxo Group Ltd Intermediates for use in the preparation of cephalosporin antibiotics
US4329453A (en) * 1979-10-02 1982-05-11 Glaxo Group Limited Cephalosporin antibiotic
CA1213882A (fr) * 1982-03-04 1986-11-12 Jun Okumura Cephalosporines
US4406899A (en) * 1982-03-04 1983-09-27 Bristol-Myers Company Cephalosporins
US4525473A (en) * 1983-03-30 1985-06-25 Bristol-Myers Company Cephalosporins
US4537959A (en) * 1984-03-26 1985-08-27 Eli Lilly And Company Crystalline cephalosporin antibiotic salt
US4751295A (en) * 1984-04-09 1988-06-14 Bristol-Myers Company Cephalosporin derivatives
US4749694A (en) * 1984-04-26 1988-06-07 Merck & Co., Inc. Novel lysine esters used as absorption
FR2585705B1 (fr) * 1985-08-05 1989-01-13 Bristol Myers Co Sels de cephalosporine et compositions injectables
US4808617A (en) * 1985-12-18 1989-02-28 Bristol-Myers Company Lyophilized or precipitated cephalosporin zwitterion and salt combination
US4791196A (en) * 1986-09-26 1988-12-13 Sankyo Company Limited Crystalline cephem carboxylic acid addition salt

Also Published As

Publication number Publication date
DE3901359A1 (de) 1989-10-05
ATA8589A (de) 1994-12-15
GB2213819A (en) 1989-08-23
HK72292A (en) 1992-10-02
JPH0725768B2 (ja) 1995-03-22
SE505258C2 (sv) 1997-07-21
FI86854C (fi) 1992-10-26
SG75492G (en) 1992-10-02
JPH029885A (ja) 1990-01-12
FI86854B (fi) 1992-07-15
FI890213A0 (fi) 1989-01-16
IT8947539A0 (it) 1988-01-17
CA1298288C (fr) 1992-03-31
FR2626003B1 (fr) 1992-10-16
DK162054C (da) 1992-02-10
GR1001218B (el) 1993-06-21
GB2213819B (en) 1991-11-27
SK24389A3 (en) 2000-12-11
SE8900173D0 (sv) 1989-01-18
NL8900111A (nl) 1989-08-16
SK281768B6 (sk) 2001-07-10
CZ24389A3 (en) 1996-08-14
KR950003612B1 (ko) 1995-04-17
FI890213A (fi) 1989-07-20
ZA89407B (en) 1989-09-27
DK20789A (da) 1989-07-20
BE1002749A5 (fr) 1991-05-28
AT399878B (de) 1995-08-25
SE8900173L (en) 1989-01-18
HU205940B (en) 1992-07-28
EG18749A (en) 1993-12-30
DE3901359C2 (fr) 1992-04-30
PT89474A (pt) 1990-02-08
NL192266B (nl) 1996-12-02
HUT50347A (en) 1990-01-29
YU221188A (en) 1990-04-30
FR2626003A1 (fr) 1989-07-21
DD284807A5 (de) 1990-11-28
NZ227605A (en) 1991-06-25
GB8901073D0 (en) 1989-03-15
DK20789D0 (da) 1989-01-18
IT1229528B (it) 1991-09-04
LU87432A1 (fr) 1989-08-30
NL192266C (nl) 1997-04-03
CZ281602B6 (cs) 1996-11-13
IE890144L (en) 1989-07-19
KR890011895A (ko) 1989-08-23
AU2862389A (en) 1989-07-20
IE67447B1 (en) 1996-04-03
DK162054B (da) 1991-09-09
DD283397A5 (de) 1990-10-10
US4910301A (en) 1990-03-20
PT89474B (pt) 1993-12-31
CY1663A (en) 1993-05-14
ES2012948A6 (es) 1990-04-16
AU615509B2 (en) 1991-10-03

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