LU83886A1 - Nouveaux derives de la furo-(3,4-c)-pyridine leur preparation et leur emploi therapeutique - Google Patents

Nouveaux derives de la furo-(3,4-c)-pyridine leur preparation et leur emploi therapeutique Download PDF

Info

Publication number
LU83886A1
LU83886A1 LU83886A LU83886A LU83886A1 LU 83886 A1 LU83886 A1 LU 83886A1 LU 83886 A LU83886 A LU 83886A LU 83886 A LU83886 A LU 83886A LU 83886 A1 LU83886 A1 LU 83886A1
Authority
LU
Luxembourg
Prior art keywords
radical
carbon atoms
pyridine
furo
alpha
Prior art date
Application number
LU83886A
Other languages
English (en)
French (fr)
Inventor
A Esanu
Original Assignee
Scras
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scras filed Critical Scras
Publication of LU83886A1 publication Critical patent/LU83886A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
LU83886A 1981-02-10 1982-01-21 Nouveaux derives de la furo-(3,4-c)-pyridine leur preparation et leur emploi therapeutique LU83886A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8104072 1981-02-10
GB8104072 1981-02-10

Publications (1)

Publication Number Publication Date
LU83886A1 true LU83886A1 (fr) 1982-06-30

Family

ID=10519587

Family Applications (1)

Application Number Title Priority Date Filing Date
LU83886A LU83886A1 (fr) 1981-02-10 1982-01-21 Nouveaux derives de la furo-(3,4-c)-pyridine leur preparation et leur emploi therapeutique

Country Status (34)

Country Link
US (1) US4383998A (es)
JP (1) JPS57150688A (es)
KR (1) KR870000206B1 (es)
AR (1) AR230284A1 (es)
AU (1) AU545876B2 (es)
BE (1) BE891797A (es)
CA (1) CA1175837A (es)
CH (1) CH649554A5 (es)
DE (1) DE3204596A1 (es)
DK (1) DK157551C (es)
DZ (1) DZ376A1 (es)
ES (1) ES8302714A1 (es)
FI (1) FI75347C (es)
FR (2) FR2499406A1 (es)
GB (1) GB2092586B (es)
GR (1) GR75905B (es)
HK (1) HK22485A (es)
HU (1) HU185088B (es)
IE (1) IE52376B1 (es)
IL (1) IL64759A (es)
IN (1) IN156817B (es)
IT (1) IT1157252B (es)
LU (1) LU83886A1 (es)
MA (1) MA19378A1 (es)
MX (1) MX6983E (es)
NL (1) NL186697C (es)
NO (1) NO156373C (es)
NZ (1) NZ199528A (es)
OA (1) OA07003A (es)
PT (1) PT74408B (es)
SE (1) SE456994B (es)
SG (1) SG85384G (es)
YU (1) YU44000B (es)
ZA (1) ZA82158B (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4735950A (en) * 1983-04-05 1988-04-05 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S) Furo-(3,4-C)-pyridine derivatives and therapeutic composition containing the same
IN160104B (es) * 1983-04-05 1987-06-27 Scras
GB8327817D0 (en) * 1983-10-18 1983-11-16 Scras 4-halo-furo-(3 4-c)-pyridine derivatives
GB8330517D0 (en) * 1983-11-16 1983-12-21 Scras 6-vinyl-furo-(3,4-c)pyridine derivatives
GB8330658D0 (en) * 1983-11-17 1983-12-29 Scras 7-carboxymethoxy-furo-(3,4-c)-pyridine derivatives
GB8402740D0 (en) * 1984-02-02 1984-03-07 Scras Furo-(3 4-c)-pyridine derivatives
GB8414559D0 (en) * 1984-06-07 1984-07-11 Scras Pyridine derivatives
GB8422379D0 (en) * 1984-09-05 1984-10-10 Scras Derivatives
GB8427218D0 (en) * 1984-10-27 1984-12-05 Scras Pyridine derivatives
DE3519693A1 (de) * 1985-06-01 1987-01-02 Basf Ag Pyridin-derivate, ihre herstellung und verwendung
GB8808001D0 (en) * 1988-04-06 1988-05-05 Scras Stereospecific preparative process for furol(3,4-c)pyridine derivatives
DE3990349T1 (de) * 1988-04-06 1990-04-26 Scras Stereospezifisches verfahren zur herstellung von enantiomeren von furo(3,4-c)pyridin, so erhaltene verbindungen und therapeutische zusammensetzungen auf basis dieser verbindungen
GB8907480D0 (en) * 1989-04-03 1989-05-17 Scaras Societe De Conseils De Separation of insomers of furo(3,4-c)pyridine derivatives
GB8917168D0 (en) * 1989-07-27 1989-09-13 Scras Asymmetric synthesis of furo(3,4-c)pyridine derivatives
US5130252A (en) * 1990-05-14 1992-07-14 Synthetech, Inc. Resolution of furopyridine enantiomers and synthetic precursors thereof
GB0221494D0 (en) * 2002-09-16 2002-10-23 Generics Uk Ltd Novel processes for the preparation of 1.3-dihydro-6-methylfuro (3,4-c) pyndin derivatives
HUP0300990A2 (hu) * 2003-04-15 2005-05-30 SynoSens Kutató és Fejlesztő Kft. Szinergista gyógyszer-kombináció a diabetesz megelőzésére vagy kezelésére
US20060089374A1 (en) * 2003-07-17 2006-04-27 Glenn Cornett Enantiomeric compositions of cicletanine, alone and in combination with other agents, for the treatment of disease
WO2005009446A1 (en) * 2003-07-17 2005-02-03 Cotherix, Inc. Combination therapies for treatment of hypertension and complications in patients with diabetes or metabolic syndrome
EP1804795A4 (en) * 2004-09-22 2007-11-07 Cornett Glen ENANTIOMERIC COMPOSITIONS OF CICLETANINE, ALONE OR COMBINED WITH OTHER AGENTS, USED FOR THERAPEUTIC PURPOSES
US20060154959A1 (en) * 2005-01-13 2006-07-13 Navitas Pharma Combination therapies of cicletanine and carvedilol
US20060153934A1 (en) * 2005-01-13 2006-07-13 Navitas Pharma Combination therapies of cicletanine and magnesium
US20080096915A1 (en) * 2005-01-13 2008-04-24 Greenberg Traurig LLP Compositions for the treatment of metabolic disorders
US20070141174A1 (en) * 2005-01-13 2007-06-21 Navitas Pharma, Inc. Enantiomeric compositions of cicletanine, in combination with other agents, for the treatment of hypertension
US20070105817A1 (en) * 2005-11-09 2007-05-10 Jim Page Use of cicletanine and other furopyridines for treatment of systolic-predominant hypertension, isolated systolic hypertension, elevated pulse pressure, and general hypertension
CA2674367A1 (en) * 2007-01-03 2008-07-17 Glenn V. Cornett Cicletanine and pkc inhibitors in the treatment of pulmonary and cardiac disorders
AR073259A1 (es) * 2008-07-29 2010-10-28 Merck & Co Inc Derivados de furosemida utiles como diureticos
US8214941B2 (en) 2008-10-02 2012-07-10 Kohler Co. Slip-fit clamping system for mounting a fitting on a wall
EP2485734B1 (en) * 2009-10-09 2014-07-02 Merck Sharp & Dohme Corp. Diuretics
EP2498605B1 (en) * 2009-10-29 2014-08-27 Merck Sharp & Dohme Corp. Diuretics
WO2015103445A1 (en) * 2013-12-31 2015-07-09 Rockey Don C Systems, methods, techniques, and compounds in research and treatment of portal hypertension and other conditions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA786269B (en) * 1977-11-25 1979-10-31 Scras New pyridine derivative,its preparation and use

Also Published As

Publication number Publication date
NL8200180A (nl) 1982-09-01
NO820253L (no) 1982-08-11
ES509449A0 (es) 1983-01-16
GR75905B (es) 1984-08-02
JPH0261477B2 (es) 1990-12-20
US4383998A (en) 1983-05-17
DE3204596C2 (es) 1991-07-04
FR2499406B1 (es) 1984-03-30
ZA82158B (en) 1982-11-24
BE891797A (fr) 1982-04-30
GB2092586B (en) 1984-09-26
IE820288L (en) 1982-08-10
DK157551C (da) 1990-06-11
IL64759A (en) 1985-09-29
GB2092586A (en) 1982-08-18
IE52376B1 (en) 1987-09-30
HK22485A (en) 1985-03-29
MA19378A1 (fr) 1982-10-01
IN156817B (es) 1985-11-09
PT74408A (en) 1982-03-01
NO156373C (no) 1987-09-09
FI75347B (fi) 1988-02-29
KR870000206B1 (ko) 1987-02-16
AU545876B2 (en) 1985-08-01
SE8200744L (sv) 1982-08-11
AU8029482A (en) 1982-08-19
DZ376A1 (fr) 2004-09-13
AR230284A1 (es) 1984-03-01
HU185088B (en) 1984-11-28
DK157551B (da) 1990-01-22
PT74408B (en) 1983-07-07
SG85384G (en) 1985-06-07
IT1157252B (it) 1987-02-11
NL186697B (nl) 1990-09-03
FR2499574A1 (fr) 1982-08-13
IT8219502A0 (it) 1982-02-08
OA07003A (fr) 1983-08-31
ES8302714A1 (es) 1983-01-16
JPS57150688A (en) 1982-09-17
NO156373B (no) 1987-06-01
CA1175837A (en) 1984-10-09
MX6983E (es) 1987-01-19
CH649554A5 (fr) 1985-05-31
DK54382A (da) 1982-08-11
NL186697C (nl) 1991-02-01
DE3204596A1 (de) 1982-09-09
SE456994B (sv) 1988-11-21
FI820353L (fi) 1982-08-11
YU25382A (en) 1984-08-31
IL64759A0 (en) 1982-03-31
YU44000B (en) 1990-02-28
FR2499574B1 (es) 1984-03-30
FR2499406A1 (fr) 1982-08-13
NZ199528A (en) 1984-02-03
KR830009106A (ko) 1983-12-17
FI75347C (fi) 1988-06-09

Similar Documents

Publication Publication Date Title
LU83886A1 (fr) Nouveaux derives de la furo-(3,4-c)-pyridine leur preparation et leur emploi therapeutique
CH660191A5 (fr) Derives de la furo-(3,4-c)-pyridine, leur preparation et compositions therapeutiques contenant ces derives.
SU1087075A3 (ru) Способ получени производных фталазин-4-ил-уксусной кислоты или их солей
CA1036597A (fr) Pyrimidines utilisables comme medicaments antidiabetiques et hypocholesterolemiants
CH635813A5 (fr) 1,9-dihydroxyoctahydrophenanthrenes et medicament les contenant.
LU85635A1 (fr) Nouveaux derives de la vinyl-6 furo-(3,4-c)-pyridine,leur preparation et compositions pharmaceutiques a base de ces composes
CH653025A5 (fr) Oxazolidine-2,4-diones substituees en position 5 douees d'activite hypoglycemique.
EP0119932B1 (en) New 2-((2,6-dichlorophenyl)amine)phenylacetoxyacetyl derivatives, the process for preparing the same and their use in therapeutics
FR2509734A1 (fr) Thiazolo(3,2-a)pyrimidines substituees et procedes pour leur preparation
FR2551063A1 (fr) Nouveaux dimethyl-2,5 pyrroles, leur procede de preparation et leur application en therapeutique
LU85583A1 (fr) Derives de la chloro-4-furo-(3,4-c)-pyridine,leur procede de preparation et compositions therapeutiques a base de ces derives
FR2572405A1 (fr) Nouveaux derives de la phenethylaminoalcoyle-6 furo-(3,4-c)-pyridine et leur procede de preparation
EP0179428A2 (en) Indoleacetic acid derivative and a pharmaceutical preparation
LU86706A1 (fr) Nouveaux derives du benzo(4,5)cyclohepta(1,2-b)thiophene,leur preparation et leur utilisation comme medicaments
KR950008316B1 (ko) 1-히드록시-5-옥소-5H-피리도[3,2-a]페녹사진-3-카르복실산 에스테르
LU86053A1 (fr) Nouveaux derives de l'aminomethyle-6 furo-(3,4-c)-pyridine,leur preparation et compositions therapeutiques en contenant
EP0445116A1 (fr) [(aryl-4-piperazinyl-1)-2 ethoxy]-3 p-cymene, les derives ortho, meta, para monosubstitues ou disubstitues sur le noyau phenyle dudit produit, le procede de preparation desdits derives, et les medicaments contenant lesdits composes comme principe actif
US4218473A (en) Derivatives of 4-cyclohexyl-1-naphthalene-acetic acid and their use as drugs
US4113960A (en) 3-(4'-Alkoxy-benzoyl)-1,2,2-trimethyl-cyclopentane-carboxylic acids, their optical isomers and drugs containing such compounds
SU1739851A3 (ru) Способ получени производных тиено(3 @ ,4 @ :4,5)имидазо(2,1- @ )тиазола
FR2563520A1 (fr) Nouveaux derives d'apovincaminol, procede pour leur preparation et compositions pharmaceutiques les contenant
LU86052A1 (fr) Nouveau procede de preparation des derives de la furo-(3,4-c)-pyridine substitues en position 6
LU85690A1 (fr) Nouveaux derives de a pyrazolo (1,5-a) pyridine,leur preparation et les compositions therapeutiques qui les contiennent
JPS61129179A (ja) １−ベンズオキセピン−５−オン誘導体
WO1986000069A1 (fr) NOUVEAUX DERIVES DE L'AMINOMETHYL-6 FURO-(3,4-c)-PYRIDINE, LEUR PROCEDE DE PREPARATION ET COMPOSITIONS THERAPEUTIQUES LES CONTENANT