JPS57150688A - Furo(3,4-c)pyridine derivative, manufacture and medicinal composition containing same - Google Patents

Furo(3,4-c)pyridine derivative, manufacture and medicinal composition containing same

Info

Publication number
JPS57150688A
JPS57150688A JP57019038A JP1903882A JPS57150688A JP S57150688 A JPS57150688 A JP S57150688A JP 57019038 A JP57019038 A JP 57019038A JP 1903882 A JP1903882 A JP 1903882A JP S57150688 A JPS57150688 A JP S57150688A
Authority
JP
Japan
Prior art keywords
furo
manufacture
composition containing
medicinal composition
containing same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP57019038A
Other languages
English (en)
Other versions
JPH0261477B2 (ja
Inventor
Esanu Andore
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DO KONSEIYU DO RUSHIERUSHIE E
DO KONSEIYU DO RUSHIERUSHIE E DAATSUPURIKAASHIYON SHIYANTEIFUITSUKU SOC
Original Assignee
DO KONSEIYU DO RUSHIERUSHIE E
DO KONSEIYU DO RUSHIERUSHIE E DAATSUPURIKAASHIYON SHIYANTEIFUITSUKU SOC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DO KONSEIYU DO RUSHIERUSHIE E, DO KONSEIYU DO RUSHIERUSHIE E DAATSUPURIKAASHIYON SHIYANTEIFUITSUKU SOC filed Critical DO KONSEIYU DO RUSHIERUSHIE E
Publication of JPS57150688A publication Critical patent/JPS57150688A/ja
Publication of JPH0261477B2 publication Critical patent/JPH0261477B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
JP57019038A 1981-02-10 1982-02-10 Furo(3,4-c)pyridine derivative, manufacture and medicinal composition containing same Granted JPS57150688A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8104072 1981-02-10

Publications (2)

Publication Number Publication Date
JPS57150688A true JPS57150688A (en) 1982-09-17
JPH0261477B2 JPH0261477B2 (ja) 1990-12-20

Family

ID=10519587

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57019038A Granted JPS57150688A (en) 1981-02-10 1982-02-10 Furo(3,4-c)pyridine derivative, manufacture and medicinal composition containing same

Country Status (34)

Country Link
US (1) US4383998A (ja)
JP (1) JPS57150688A (ja)
KR (1) KR870000206B1 (ja)
AR (1) AR230284A1 (ja)
AU (1) AU545876B2 (ja)
BE (1) BE891797A (ja)
CA (1) CA1175837A (ja)
CH (1) CH649554A5 (ja)
DE (1) DE3204596A1 (ja)
DK (1) DK157551C (ja)
DZ (1) DZ376A1 (ja)
ES (1) ES8302714A1 (ja)
FI (1) FI75347C (ja)
FR (2) FR2499574A1 (ja)
GB (1) GB2092586B (ja)
GR (1) GR75905B (ja)
HK (1) HK22485A (ja)
HU (1) HU185088B (ja)
IE (1) IE52376B1 (ja)
IL (1) IL64759A (ja)
IN (1) IN156817B (ja)
IT (1) IT1157252B (ja)
LU (1) LU83886A1 (ja)
MA (1) MA19378A1 (ja)
MX (1) MX6983E (ja)
NL (1) NL186697C (ja)
NO (1) NO156373C (ja)
NZ (1) NZ199528A (ja)
OA (1) OA07003A (ja)
PT (1) PT74408B (ja)
SE (1) SE456994B (ja)
SG (1) SG85384G (ja)
YU (1) YU44000B (ja)
ZA (1) ZA82158B (ja)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59193888A (ja) * 1983-04-05 1984-11-02 ソシエテ・ド・コンセイユ・ド・ルシエルシエ・エ・ダアツプリカ−シヨン・シヤンテイフイツク・（エス．セ−．エ−ル．ア−．エス） フロ−（３，４−ｃ）−ピリジン誘導体、その製造法及びそれを含有する医薬
JPS60104090A (ja) * 1983-10-18 1985-06-08 ソシエテ・ド・コンセイユ・ド・ルシエルシエ・エ・ダアツプリカーシヨン・シヤンテイフイツク・（エス．セー．エール．アー．エス） ４―クロロ―フロ―（３，４―ｃ）―ピリジン誘導体、その製造法並びに利尿及び降圧組成物
JPH02504394A (ja) * 1988-04-06 1990-12-13 ソシエテ・ド・コンセイユ・ド・ルシエルシエ・エ・ダアツプリカーシヨン・シヤンテイフイツク・（エス．セー．エール．アー．エス） フロ〔３，４‐ｃ〕ピリジン鏡像体の立体特異的製造方法、かくして得られた化合物及びこれの製薬組成物
JP2011529892A (ja) * 2008-07-29 2011-12-15 メルク・シャープ・エンド・ドーム・コーポレイション フロセミドのニトロ誘導体及び利尿剤としてのその使用

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4735950A (en) * 1983-04-05 1988-04-05 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S) Furo-(3,4-C)-pyridine derivatives and therapeutic composition containing the same
GB8330517D0 (en) * 1983-11-16 1983-12-21 Scras 6-vinyl-furo-(3,4-c)pyridine derivatives
GB8330658D0 (en) * 1983-11-17 1983-12-29 Scras 7-carboxymethoxy-furo-(3,4-c)-pyridine derivatives
GB8402740D0 (en) * 1984-02-02 1984-03-07 Scras Furo-(3 4-c)-pyridine derivatives
GB8414559D0 (en) * 1984-06-07 1984-07-11 Scras Pyridine derivatives
GB8422379D0 (en) * 1984-09-05 1984-10-10 Scras Derivatives
GB8427218D0 (en) * 1984-10-27 1984-12-05 Scras Pyridine derivatives
DE3519693A1 (de) * 1985-06-01 1987-01-02 Basf Ag Pyridin-derivate, ihre herstellung und verwendung
DE3990349T1 (de) * 1988-04-06 1990-04-26 Scras Stereospezifisches verfahren zur herstellung von enantiomeren von furo(3,4-c)pyridin, so erhaltene verbindungen und therapeutische zusammensetzungen auf basis dieser verbindungen
GB8907480D0 (en) * 1989-04-03 1989-05-17 Scaras Societe De Conseils De Separation of insomers of furo(3,4-c)pyridine derivatives
GB8917168D0 (en) * 1989-07-27 1989-09-13 Scras Asymmetric synthesis of furo(3,4-c)pyridine derivatives
US5130252A (en) * 1990-05-14 1992-07-14 Synthetech, Inc. Resolution of furopyridine enantiomers and synthetic precursors thereof
GB0221494D0 (en) * 2002-09-16 2002-10-23 Generics Uk Ltd Novel processes for the preparation of 1.3-dihydro-6-methylfuro (3,4-c) pyndin derivatives
HUP0300990A2 (hu) * 2003-04-15 2005-05-30 SynoSens Kutató és Fejlesztő Kft. Szinergista gyógyszer-kombináció a diabetesz megelőzésére vagy kezelésére
US20060089374A1 (en) * 2003-07-17 2006-04-27 Glenn Cornett Enantiomeric compositions of cicletanine, alone and in combination with other agents, for the treatment of disease
CA2532807A1 (en) * 2003-07-17 2005-02-03 Cotherix, Inc. Combination therapies for treatment of hypertension and complications in patients with diabetes or metabolic syndrome
CA2581337A1 (en) * 2004-09-22 2006-03-30 Glenn Cornett Enantiomeric compositions of cicletanine, alone and in combination with other agents, for the treatment of disease
US20060153934A1 (en) * 2005-01-13 2006-07-13 Navitas Pharma Combination therapies of cicletanine and magnesium
US20060154959A1 (en) * 2005-01-13 2006-07-13 Navitas Pharma Combination therapies of cicletanine and carvedilol
US20070141174A1 (en) * 2005-01-13 2007-06-21 Navitas Pharma, Inc. Enantiomeric compositions of cicletanine, in combination with other agents, for the treatment of hypertension
US20080096915A1 (en) * 2005-01-13 2008-04-24 Greenberg Traurig LLP Compositions for the treatment of metabolic disorders
US20070105817A1 (en) * 2005-11-09 2007-05-10 Jim Page Use of cicletanine and other furopyridines for treatment of systolic-predominant hypertension, isolated systolic hypertension, elevated pulse pressure, and general hypertension
US20080312241A1 (en) * 2007-01-03 2008-12-18 Gilead Sciences, Inc. Cicletanine and PKC inhibitors in the treatment of pulmonary and cardiac disorders
US8214941B2 (en) 2008-10-02 2012-07-10 Kohler Co. Slip-fit clamping system for mounting a fitting on a wall
US8377911B2 (en) * 2009-10-09 2013-02-19 Merck Sharp & Dohme Corp. Diuretics
WO2011053519A1 (en) * 2009-10-29 2011-05-05 Merck Sharp & Dohme Corp. Diuretics
WO2015103445A1 (en) * 2013-12-31 2015-07-09 Rockey Don C Systems, methods, techniques, and compounds in research and treatment of portal hypertension and other conditions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA786269B (en) * 1977-11-25 1979-10-31 Scras New pyridine derivative,its preparation and use

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59193888A (ja) * 1983-04-05 1984-11-02 ソシエテ・ド・コンセイユ・ド・ルシエルシエ・エ・ダアツプリカ−シヨン・シヤンテイフイツク・（エス．セ−．エ−ル．ア−．エス） フロ−（３，４−ｃ）−ピリジン誘導体、その製造法及びそれを含有する医薬
JPH0556353B2 (ja) * 1983-04-05 1993-08-19 Scras
JPS60104090A (ja) * 1983-10-18 1985-06-08 ソシエテ・ド・コンセイユ・ド・ルシエルシエ・エ・ダアツプリカーシヨン・シヤンテイフイツク・（エス．セー．エール．アー．エス） ４―クロロ―フロ―（３，４―ｃ）―ピリジン誘導体、その製造法並びに利尿及び降圧組成物
JPH0339513B2 (ja) * 1983-10-18 1991-06-14 Konseiyu Do Rusherushu E Dapurikashion Shianteifuiiku Scras Soc
JPH02504394A (ja) * 1988-04-06 1990-12-13 ソシエテ・ド・コンセイユ・ド・ルシエルシエ・エ・ダアツプリカーシヨン・シヤンテイフイツク・（エス．セー．エール．アー．エス） フロ〔３，４‐ｃ〕ピリジン鏡像体の立体特異的製造方法、かくして得られた化合物及びこれの製薬組成物
JP2680456B2 (ja) * 1988-04-06 1997-11-19 ソシエテ・ド・コンセイユ・ド・ルシエルシエ・エ・ダアツプリカーシヨン・シヤンテイフイツク・（エス．セー．エール．アー．エス） フロ〔３，４―ｃ〕ピリジン鏡像体の立体特異的製造方法
JP2011529892A (ja) * 2008-07-29 2011-12-15 メルク・シャープ・エンド・ドーム・コーポレイション フロセミドのニトロ誘導体及び利尿剤としてのその使用

Also Published As

Publication number Publication date
FI75347B (fi) 1988-02-29
NO156373C (no) 1987-09-09
GB2092586B (en) 1984-09-26
IL64759A (en) 1985-09-29
FR2499574B1 (ja) 1984-03-30
PT74408B (en) 1983-07-07
HK22485A (en) 1985-03-29
IT8219502A0 (it) 1982-02-08
DK157551B (da) 1990-01-22
DE3204596C2 (ja) 1991-07-04
SE456994B (sv) 1988-11-21
DK54382A (da) 1982-08-11
FI820353L (fi) 1982-08-11
NL186697C (nl) 1991-02-01
DZ376A1 (fr) 2004-09-13
GR75905B (ja) 1984-08-02
IN156817B (ja) 1985-11-09
AR230284A1 (es) 1984-03-01
FR2499406A1 (fr) 1982-08-13
JPH0261477B2 (ja) 1990-12-20
IE52376B1 (en) 1987-09-30
NL186697B (nl) 1990-09-03
US4383998A (en) 1983-05-17
ZA82158B (en) 1982-11-24
MA19378A1 (fr) 1982-10-01
BE891797A (fr) 1982-04-30
KR830009106A (ko) 1983-12-17
DE3204596A1 (de) 1982-09-09
CA1175837A (en) 1984-10-09
GB2092586A (en) 1982-08-18
PT74408A (en) 1982-03-01
NZ199528A (en) 1984-02-03
ES509449A0 (es) 1983-01-16
YU44000B (en) 1990-02-28
IE820288L (en) 1982-08-10
MX6983E (es) 1987-01-19
OA07003A (fr) 1983-08-31
YU25382A (en) 1984-08-31
FI75347C (fi) 1988-06-09
KR870000206B1 (ko) 1987-02-16
SE8200744L (sv) 1982-08-11
NO820253L (no) 1982-08-11
IL64759A0 (en) 1982-03-31
CH649554A5 (fr) 1985-05-31
SG85384G (en) 1985-06-07
NL8200180A (nl) 1982-09-01
NO156373B (no) 1987-06-01
AU545876B2 (en) 1985-08-01
IT1157252B (it) 1987-02-11
FR2499406B1 (ja) 1984-03-30
DK157551C (da) 1990-06-11
FR2499574A1 (fr) 1982-08-13
HU185088B (en) 1984-11-28
AU8029482A (en) 1982-08-19
LU83886A1 (fr) 1982-06-30
ES8302714A1 (es) 1983-01-16

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