IL76894A0 - Tricyclic pyridine derivatives,their manufacture and pharmaceutical compositions containing them - Google Patents

Tricyclic pyridine derivatives,their manufacture and pharmaceutical compositions containing them

Info

Publication number
IL76894A0
IL76894A0 IL76894A IL7689485A IL76894A0 IL 76894 A0 IL76894 A0 IL 76894A0 IL 76894 A IL76894 A IL 76894A IL 7689485 A IL7689485 A IL 7689485A IL 76894 A0 IL76894 A0 IL 76894A0
Authority
IL
Israel
Prior art keywords
manufacture
pharmaceutical compositions
compositions containing
pyridine derivatives
tricyclic pyridine
Prior art date
Application number
IL76894A
Other versions
IL76894A (en
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority to IL88046A priority Critical patent/IL88046A/en
Publication of IL76894A0 publication Critical patent/IL76894A0/en
Priority to IL88046A priority patent/IL88046A0/en
Publication of IL76894A publication Critical patent/IL76894A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D455/00Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/02Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D455/00Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/03Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/04Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
    • C07D455/06Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine containing benzo [a] quinolizine ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/12Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D513/14Ortho-condensed systems
IL76894A 1984-11-06 1985-10-31 Aryl-substituted tricyclic pyridinone derivatives,their manufacture and pharmaceutical compositions containing them IL76894A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IL88046A IL88046A (en) 1984-11-06 1985-10-31 Aryl-substituted tricyclic thiazolium derivatives
IL88046A IL88046A0 (en) 1984-11-06 1988-10-14 Tricyclic pyridine derivatives

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH530484 1984-11-06
CH383685 1985-09-05

Publications (2)

Publication Number Publication Date
IL76894A0 true IL76894A0 (en) 1986-02-28
IL76894A IL76894A (en) 1989-06-30

Family

ID=25693960

Family Applications (1)

Application Number Title Priority Date Filing Date
IL76894A IL76894A (en) 1984-11-06 1985-10-31 Aryl-substituted tricyclic pyridinone derivatives,their manufacture and pharmaceutical compositions containing them

Country Status (23)

Country Link
US (2) US4735940A (en)
EP (2) EP0183994B1 (en)
JP (1) JPH0692405B2 (en)
CN (1) CN1016871B (en)
AR (1) AR242579A1 (en)
AT (1) ATE51232T1 (en)
AU (1) AU584132B2 (en)
CA (1) CA1277659C (en)
DE (2) DE3576691D1 (en)
DK (1) DK507685A (en)
DO (1) DOP1985004378A (en)
ES (8) ES8705436A1 (en)
FI (1) FI89049C (en)
GB (1) GB2169288B (en)
HU (1) HU205353B (en)
IE (1) IE58850B1 (en)
IL (1) IL76894A (en)
IS (1) IS1469B6 (en)
MC (1) MC1707A1 (en)
MY (1) MY103172A (en)
NO (1) NO171914C (en)
PT (1) PT81431B (en)
ZW (1) ZW17385A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4889848A (en) * 1984-11-06 1989-12-26 Hoffmann-La Roche Inc. Tricyclic pyridine derivatives
NO162285C (en) * 1984-11-23 1989-12-06 Fujisawa Pharmaceutical Co ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE QUINOLIZINON DERIVATIVES.
CA1317945C (en) * 1985-12-13 1993-05-18 Ulf Fischer Tricyclic pyridazopyridone derivatives
EP0294599A3 (en) * 1987-06-12 1990-05-09 F. Hoffmann-La Roche Ag Tricyclic pyridone derivatives
ATE145208T1 (en) * 1990-07-06 1996-11-15 Yoshitomi Pharmaceutical CONDENSED THIOPHENE COMPOUNDS AND THEIR USE
CA2058640A1 (en) * 1991-01-25 1992-07-26 Richard R. Scherschlicht Tricyclic pyridone derivative
US5532240A (en) * 1991-12-26 1996-07-02 Yoshitomi Pharmaceutical Industries, Ltd. Condensed thiophene compound and pharmaceutical use thereof
FR2689129B1 (en) * 1992-03-27 1995-05-12 Atochem Elf Sa New derivatives of 3-mercapto-2-thenoic acid and their preparation processes.
EP0650966A1 (en) * 1993-10-28 1995-05-03 F. Hoffmann-La Roche Ag Process for the preparation of a benzo(a)quinolizinone derivative
US5869500A (en) * 1996-12-13 1999-02-09 Hoffmann-La Roche Inc. Pyridone compounds useful in treating Alzheimer's disease
GB9708945D0 (en) * 1997-05-01 1997-06-25 Merck Sharp & Dohme Therapeutic agents
GB0119828D0 (en) * 2001-08-14 2001-10-10 Merck Sharp & Dohme Therapeutic agents
GB0119803D0 (en) * 2001-08-14 2001-10-10 Merck Sharp & Dohme Therapeutic agents
ES2374458T3 (en) 2006-01-13 2012-02-16 The Trustees Of The University Of Pennsylvania IMMUNOTHERAPEUTIC VACCINES AND AGENTS USING OPTIMIZED IL-15 IN CODONS, AND METHODS FOR USING THEMSELVES.
JP2016531122A (en) 2013-08-08 2016-10-06 ザ スクリップス リサーチ インスティテュートThe Scripps Research Institute Methods for site-specific enzyme labeling of nucleic acids in vitro by incorporation of unnatural nucleotides

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ191763A (en) * 1978-10-13 1984-05-31 Hoffmann La Roche 7-beta-phenyl-quinolidines, intermediates and pharmaceutical compositions
EP0067565A1 (en) * 1981-06-16 1982-12-22 Beecham Group Plc Pharmaceutically active compounds
GB8408292D0 (en) * 1984-03-30 1984-05-10 Fujisawa Pharmaceutical Co Quinolizinone compound
GB8420602D0 (en) * 1984-08-14 1984-09-19 Wyeth John & Brother Ltd Thienoquinolizines
NO162285C (en) * 1984-11-23 1989-12-06 Fujisawa Pharmaceutical Co ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE QUINOLIZINON DERIVATIVES.
GB8509435D0 (en) * 1985-04-12 1985-05-15 Beecham Group Plc Intermediates & process
AU582663B2 (en) * 1985-08-10 1989-04-06 John Wyeth & Brother Limited Sulphonamides
US4686226A (en) * 1985-09-03 1987-08-11 Merck & Co., Inc. Substituted benzo[b]furo- and benzo[b]thieno quinolizines

Also Published As

Publication number Publication date
IL76894A (en) 1989-06-30
ES554430A0 (en) 1987-12-01
ZW17385A1 (en) 1986-02-19
CA1277659C (en) 1990-12-11
EP0183994A1 (en) 1986-06-11
ES8705436A1 (en) 1987-05-01
ES554431A0 (en) 1987-12-01
GB8527196D0 (en) 1985-12-11
DK507685A (en) 1986-05-07
EP0318682B1 (en) 1993-03-31
MY103172A (en) 1993-05-29
GB2169288A (en) 1986-07-09
FI89049B (en) 1993-04-30
MC1707A1 (en) 1986-09-22
IE58850B1 (en) 1993-11-17
GB2169288B (en) 1989-06-01
FI89049C (en) 1993-08-10
DK507685D0 (en) 1985-11-04
NO171914B (en) 1993-02-08
AU4924185A (en) 1986-05-15
FI854211A0 (en) 1985-10-28
DOP1985004378A (en) 1991-04-05
AR242579A1 (en) 1993-04-30
ES8800935A1 (en) 1987-12-01
JPS61115082A (en) 1986-06-02
CN85108120A (en) 1986-11-05
HU205353B (en) 1992-04-28
ES554429A0 (en) 1987-12-01
DE3576691D1 (en) 1990-04-26
ES8800936A1 (en) 1987-12-01
ES8800939A1 (en) 1987-12-01
ES8800933A1 (en) 1987-12-01
ES554428A0 (en) 1987-12-01
IE852751L (en) 1986-05-06
ES8800937A1 (en) 1987-12-01
EP0318682A2 (en) 1989-06-07
ATE51232T1 (en) 1990-04-15
ES8800932A1 (en) 1987-12-01
JPH0692405B2 (en) 1994-11-16
ES8800934A1 (en) 1987-12-01
NO171914C (en) 1993-05-19
PT81431A (en) 1985-12-01
IS1469B6 (en) 1991-09-24
EP0183994B1 (en) 1990-03-21
CN1016871B (en) 1992-06-03
HUT38638A (en) 1986-06-30
ES554427A0 (en) 1987-12-01
AU584132B2 (en) 1989-05-18
EP0318682A3 (en) 1989-08-16
ES554432A0 (en) 1987-12-01
ES548532A0 (en) 1987-05-01
PT81431B (en) 1988-03-03
US5036066A (en) 1991-07-30
DE3587235D1 (en) 1993-05-06
NO854404L (en) 1986-05-07
ES554426A0 (en) 1987-12-01
IS3054A7 (en) 1986-05-07
US4735940A (en) 1988-04-05

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
RH1 Patent not in force