LU75903A1 - - Google Patents

Info

Publication number
LU75903A1
LU75903A1 LU75903A LU75903A LU75903A1 LU 75903 A1 LU75903 A1 LU 75903A1 LU 75903 A LU75903 A LU 75903A LU 75903 A LU75903 A LU 75903A LU 75903 A1 LU75903 A1 LU 75903A1
Authority
LU
Luxembourg
Application number
LU75903A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to LU75903A priority Critical patent/LU75903A1/xx
Priority to DE19762655570 priority patent/DE2655570A1/de
Priority to NZ182836A priority patent/NZ182836A/xx
Priority to GB51463/76A priority patent/GB1537130A/en
Priority to CH1549976A priority patent/CH624967A5/de
Priority to AU20472/76A priority patent/AU508224B2/en
Priority to FR7637257A priority patent/FR2334363A1/fr
Priority to HU76CI1705A priority patent/HU175583B/hu
Priority to NL7613791A priority patent/NL7613791A/xx
Priority to DK557876A priority patent/DK143708C/da
Priority to IL51087A priority patent/IL51087A/xx
Priority to AT913976A priority patent/AT357703B/de
Priority to IE2700/76A priority patent/IE44473B1/en
Priority to DD7600196266A priority patent/DD128683A5/xx
Priority to CA267,605A priority patent/CA1056371A/en
Priority to ES454120A priority patent/ES454120A1/es
Priority to JP14932676A priority patent/JPS5289662A/ja
Priority to SE7706673A priority patent/SE436751B/xx
Priority to DK256977A priority patent/DK146017C/da
Priority to NL7710089A priority patent/NL7710089A/xx
Priority to DE2743069A priority patent/DE2743069C2/de
Priority to CH1172177A priority patent/CH632279A5/de
Priority to FR7729043A priority patent/FR2366311A1/fr
Priority to AU29148/77A priority patent/AU514200B2/en
Priority to DD7700201226A priority patent/DD133150A5/xx
Priority to CY1178A priority patent/CY1178A/xx
Priority to CA287,560A priority patent/CA1101410A/en
Priority to GB40131/77A priority patent/GB1563638A/en
Priority to HU77CI1774A priority patent/HU175218B/hu
Priority to BE181243A priority patent/BE859120A/xx
Priority to ZA00775800A priority patent/ZA775800B/xx
Priority to IL53012A priority patent/IL53012A/xx
Priority to IE1979/77A priority patent/IE46047B1/en
Priority to AT0691077A priority patent/AT363197B/de
Priority to ES462763A priority patent/ES462763A1/es
Priority to JP11619377A priority patent/JPS5356652A/ja
Publication of LU75903A1 publication Critical patent/LU75903A1/xx
Priority to AT81079A priority patent/AT363199B/de
Priority to AT0081279A priority patent/AT363201B/de
Priority to AT0081179A priority patent/AT363200B/de
Priority to AT0151379A priority patent/AT363203B/de
Priority to AT0151279A priority patent/AT363202B/de
Priority to AT151479A priority patent/AT363204B/de
Priority to CH853980A priority patent/CH625810A5/de
Priority to CH853880A priority patent/CH625809A5/de
Priority to CH853780A priority patent/CH625808A5/de
Priority to CH683081A priority patent/CH631998A5/de
Priority to CH683181A priority patent/CH631999A5/de
Priority to CH683281A priority patent/CH632000A5/de
Priority to CH4682A priority patent/CH632521A5/de
Priority to SG33/83A priority patent/SG3383G/en
Priority to KE3258A priority patent/KE3258A/xx
Priority to HK166/83A priority patent/HK16683A/xx
Priority to US06/601,746 priority patent/US4619921A/en
Priority to MY92/84A priority patent/MY8400092A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C07J71/0015—Oxiranes at position 9(11)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
LU75903A 1916-09-11 1976-09-29 LU75903A1 (ja)

Priority Applications (54)

Application Number Priority Date Filing Date Title
LU75903A LU75903A1 (ja) 1976-09-29 1976-09-29
DE19762655570 DE2655570A1 (de) 1975-12-12 1976-12-08 Neue polyhalogensteroide und verfahren zu ihrer herstellung
NZ182836A NZ182836A (en) 1975-12-12 1976-12-09 9 ,21-dihalo-6 -fluoro-11 ,17 -dihydroxy 16 -methyl-pregna-1,4-diene-3,20-diones
GB51463/76A GB1537130A (en) 1975-12-12 1976-12-09 6,9,21-trihalo-steroids of the pregnane series
CH1549976A CH624967A5 (en) 1976-09-29 1976-12-09 Process for the preparation of polyhalogenated steroids
AU20472/76A AU508224B2 (en) 1975-12-12 1976-12-10 9 21-dihalogeno-11 17 -dihydroxy-6 -fluro-16-methyl-pregna-1,4-diene-3,20-diones
FR7637257A FR2334363A1 (fr) 1975-12-12 1976-12-10 Nouveaux steroides polyhalogenes utiles comme medicaments et procede pour leur preparation
HU76CI1705A HU175583B (hu) 1975-12-12 1976-12-10 Sposob poluchenija novykh poligalosteroidov
NL7613791A NL7613791A (nl) 1975-12-12 1976-12-10 Werkwijze voor de bereiding van polyhalogeen- steroiden.
DK557876A DK143708C (da) 1975-12-12 1976-12-10 Analogifremgangsmaade til fremstilling af 17alfa-acyloxy-9alfa,21-dihalogen-11beta-hydroxy-6alfa-fluor-16alfa-methyl-pregna-1,4-dien-3,20-dion-forbindelser
IL51087A IL51087A (en) 1975-12-12 1976-12-10 6 -fluoro-9 ,21-dihalogeno-11 -hydroxy-17 -(lower alkanoyloxy)-16 -methyl-pregna-184-diene-3,20-dione compounds,their manufacture and pharmaceutical compositions containing them
AT913976A AT357703B (de) 1975-12-12 1976-12-10 Verfahren zur herstellung von neuen 9alpha,21- dihalogen-11beta, 17alfa-dihydroxy-6alfa-fluor- 16alfa-methyl-pregna-1,4-dien-3,20-dion-ver- bindungen
IE2700/76A IE44473B1 (en) 1975-12-12 1976-12-10 6,9,21-trihalo-steroids of the pregnane series
DD7600196266A DD128683A5 (de) 1975-12-12 1976-12-10 Verfahren zur herstellung neuer polyhalogensteroide
CA267,605A CA1056371A (en) 1975-12-12 1976-12-10 Polyhalogeno-steroids and processes for their manufacture
ES454120A ES454120A1 (es) 1975-12-12 1976-12-10 Procedimiento para la obtencion de polihalogenoesteroides.
JP14932676A JPS5289662A (en) 1975-12-12 1976-12-11 Novel polyhalogenoosteroid and preparation thereof
SE7706673A SE436751B (sv) 1976-09-29 1977-06-08 Forfarande enligt krav 1 i patentet 7613920-3 (publ.nr 423903) for framstellning av 17alfa-acyloxi-9alfa, 21-dihalogen-11beta-hydroxi-6alfa-fluor-16beta-metyl-pregna-1,4-dien-3,20-dion-foreningar
DK256977A DK146017C (da) 1976-09-29 1977-06-09 Analogifremgangsmaade til fremstilling af 17alfa-acyloxy-9alfa,21-dihalogen-11beta-hydroxy-6alfa-fluor-16beta-methyl-pregna-1,4-dien-3,20-dion-forbindelser
NL7710089A NL7710089A (nl) 1976-09-29 1977-09-14 Werkwijze voor de bereiding van veelvoudig gehalogeneerde steroiden.
DE2743069A DE2743069C2 (de) 1976-09-29 1977-09-24 21-Chlor-6α-fluor-9α-halogen-11β-hydroxy-16β-methyl-17α-propionyloxy-pregna-1,4-dien-3,20-dion-Verbindungen, Verfahren zu ihrer Herstellung und pharmazeutische Präparate, welche diese Verbindungen enthalten
CH1172177A CH632279A5 (en) 1976-09-29 1977-09-26 Process for the preparation of polyhalogenated steroids
FR7729043A FR2366311A1 (fr) 1976-09-29 1977-09-27 Procede pour la preparation de steroides polyhalogenes utiles comme medicaments
AU29148/77A AU514200B2 (en) 1916-09-11 1977-09-27 9a, 21-dijalogeno-11b, 17a-dihydroxy-6a-fluro-16b-methyl pregna-1, 4-diene-3, 20-diones
DD7700201226A DD133150A5 (de) 1976-09-29 1977-09-27 Verfahren zur herstellung von mehrfach halogenierten steroiden
CY1178A CY1178A (en) 1976-09-29 1977-09-27 21-halogenopregnane compounds
CA287,560A CA1101410A (en) 1976-09-29 1977-09-27 Polyhalogenated steroids
GB40131/77A GB1563638A (en) 1976-09-29 1977-09-27 21-halogenopregnane compounds
HU77CI1774A HU175218B (hu) 1976-09-29 1977-09-28 Sposob poluchenija poligalogeno-steroidov
BE181243A BE859120A (fr) 1976-09-29 1977-09-28 Procede pour la preparation de steroides polyhalogenes utiles comme medicaments
ZA00775800A ZA775800B (en) 1976-09-29 1977-09-28 Polyhalogenated steroids
IL53012A IL53012A (en) 1976-09-29 1977-09-28 Polyhalogenated steroids of the pregnane series,their manufacture and pharmaceutical compositions containing them
IE1979/77A IE46047B1 (en) 1976-09-29 1977-09-28 Polyhalogenated steroids
AT0691077A AT363197B (de) 1976-09-29 1977-09-28 Verfahren zur herstellung von neuen 9alpha,21-dihalogen-11beta, 17alpha-dihydroxy-6alpha-fluor-16beta-methyl-pregna-1,4-dien-3,20-dion-verbindungen
ES462763A ES462763A1 (es) 1976-09-29 1977-09-29 Procedimiento para la obtencion de polihalogeno-esteroides.
JP11619377A JPS5356652A (en) 1976-09-29 1977-09-29 Production of polyhalogenoo steroid
AT81079A AT363199B (de) 1975-12-12 1979-02-02 Verfahren zur herstellung von neuen 9alpha,21-dihalogen-11beta,17alpha-dihydroxy-6alpha-flour-16alpha-methyl-pregna-1,4-dien-3,20-dion-verbindungen
AT0081279A AT363201B (de) 1975-12-12 1979-02-02 Verfahren zur herstellung von neuen 9alpha,21-dihalogen-11beta,17alpha-dihydroxy-6alpha-
AT0081179A AT363200B (de) 1975-12-12 1979-02-02 Verfahren zur herstellung von neuen 9alpha, 21-dihalogen-11beta, 17alpha-dihydroxy-6alpha-
AT0151379A AT363203B (de) 1976-09-29 1979-02-28 Verfahren zur herstellung von neuen 9alpha,21-
AT0151279A AT363202B (de) 1976-09-29 1979-02-28 Verfahren zur herstellung von neuen mehrfach halogenierten steroiden
AT151479A AT363204B (de) 1976-09-29 1979-02-28 Verfahren zur herstellung von mehrfach halogenierten steroiden
CH853980A CH625810A5 (en) 1976-09-29 1980-11-18 Process for the preparation of polyhalogenated steroids
CH853880A CH625809A5 (en) 1976-09-29 1980-11-18 Process for the preparation of polyhalogenated steroids
CH853780A CH625808A5 (en) 1976-09-29 1980-11-18 Process for the preparation of polyhalogenated steroids
CH683081A CH631998A5 (en) 1976-09-29 1981-10-26 Process for the preparation of polyhalogenated steroids
CH683181A CH631999A5 (en) 1976-09-29 1981-10-26 Process for the preparation of polyhalogenated steroids
CH683281A CH632000A5 (en) 1976-09-29 1981-10-26 Process for the preparation of polyhalogenated steroids
CH4682A CH632521A5 (en) 1976-09-29 1982-01-06 Process for the preparation of polyhalogenated steroids
SG33/83A SG3383G (en) 1976-09-29 1983-01-20 21-halogenopregnane compounds
KE3258A KE3258A (en) 1976-09-29 1983-01-21 21-halogenopregnane compounds
HK166/83A HK16683A (en) 1976-09-29 1983-05-19 21-halogenopregnane compounds
US06/601,746 US4619921A (en) 1975-12-12 1984-04-20 Polyhalogeno-steroids
MY92/84A MY8400092A (en) 1976-09-29 1984-12-30 21 halogenopregnane compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU75903A LU75903A1 (ja) 1976-09-29 1976-09-29

Publications (1)

Publication Number Publication Date
LU75903A1 true LU75903A1 (ja) 1978-05-16

Family

ID=19728370

Family Applications (1)

Application Number Title Priority Date Filing Date
LU75903A LU75903A1 (ja) 1916-09-11 1976-09-29

Country Status (24)

Country Link
JP (1) JPS5356652A (ja)
AT (3) AT363197B (ja)
AU (1) AU514200B2 (ja)
BE (1) BE859120A (ja)
CA (1) CA1101410A (ja)
CH (9) CH624967A5 (ja)
CY (1) CY1178A (ja)
DD (1) DD133150A5 (ja)
DE (1) DE2743069C2 (ja)
DK (1) DK146017C (ja)
ES (1) ES462763A1 (ja)
FR (1) FR2366311A1 (ja)
GB (1) GB1563638A (ja)
HK (1) HK16683A (ja)
HU (1) HU175218B (ja)
IE (1) IE46047B1 (ja)
IL (1) IL53012A (ja)
KE (1) KE3258A (ja)
LU (1) LU75903A1 (ja)
MY (1) MY8400092A (ja)
NL (1) NL7710089A (ja)
SE (1) SE436751B (ja)
SG (1) SG3383G (ja)
ZA (1) ZA775800B (ja)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL187577C (nl) * 1978-04-05 1991-11-18 Sibla Srl 3-acetoxy-9beta,11beta-epoxy-pregna-1,3,5-trienen, werkwijze voor de bereiding daarvan en werkwijze voor de bereiding van 6alfa-halogeen-pregna-1,4-dieen-3-onen.
DE3227312A1 (de) * 1982-07-19 1984-01-19 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 6,16-dimethylkortikoide, ihre herstellung und verwendung
EP0523132A1 (en) * 1990-03-27 1993-01-20 Schering Corporation PROCESS FOR 9$g(a)-HYDROXY STEROID DEHYDRATION
US5972922A (en) * 1990-06-11 1999-10-26 Alcon Laboratories, Inc. Steroids which inhibit angiogenesis
CA2473471A1 (en) 2001-11-29 2003-06-12 Taro Pharmaceuticals U.S.A., Inc. Method for the preparation of 6-alpha-fluoro corticosteroids
US8809307B2 (en) 2010-11-22 2014-08-19 Dow Pharmaceutical Sciences, Inc. Pharmaceutical formulations containing corticosteroids for topical administration
US11957753B2 (en) 2010-11-22 2024-04-16 Bausch Health Ireland Limited Pharmaceutical formulations containing corticosteroids for topical administration
AU2016279801B2 (en) 2015-06-18 2021-09-09 Valeant Pharmaceuticals North America Topical compositions comprising a corticosteroid and a retinoid for treating psoriasis

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB898292A (en) * 1959-03-18 1962-06-06 Upjohn Co Improvements in or relating to steroids and the manufacture thereof
US3644340A (en) * 1970-03-19 1972-02-22 Syntex Corp Preparation of 21-chloro steroids
US3992422A (en) * 1975-08-14 1976-11-16 Schering Corporation Process for the preparation of 21-halogeno-21-desoxy-17α-acyloxy-20-keto-pregnenes

Also Published As

Publication number Publication date
AT363197B (de) 1981-07-10
BE859120A (fr) 1978-03-28
CH632521A5 (en) 1982-10-15
ZA775800B (en) 1978-08-30
IE46047L (en) 1978-03-29
FR2366311A1 (fr) 1978-04-28
CA1101410A (en) 1981-05-19
DK146017C (da) 1983-10-24
JPS5356652A (en) 1978-05-23
CH625809A5 (en) 1981-10-15
CY1178A (en) 1983-06-10
DK146017B (da) 1983-05-24
GB1563638A (en) 1980-03-26
HU175218B (hu) 1980-06-28
AU2914877A (en) 1979-04-05
FR2366311B1 (ja) 1982-12-03
DE2743069C2 (de) 1987-03-05
IL53012A (en) 1982-05-31
ES462763A1 (es) 1978-05-16
HK16683A (en) 1983-05-27
AT363203B (de) 1981-07-27
NL7710089A (nl) 1978-03-31
IE46047B1 (en) 1983-02-09
SG3383G (en) 1983-09-09
AT363202B (de) 1981-07-27
CH632279A5 (en) 1982-09-30
CH625808A5 (en) 1981-10-15
ATA691077A (de) 1980-12-15
CH631999A5 (en) 1982-09-15
CH624967A5 (en) 1981-08-31
SE7706673L (sv) 1978-03-30
ATA151379A (de) 1980-12-15
IL53012A0 (en) 1977-11-30
DE2743069A1 (de) 1978-03-30
JPS6214557B2 (ja) 1987-04-02
ATA151279A (de) 1980-12-15
CH631998A5 (en) 1982-09-15
KE3258A (en) 1983-03-04
SE436751B (sv) 1985-01-21
MY8400092A (en) 1984-12-31
CH632000A5 (en) 1982-09-15
DD133150A5 (de) 1978-12-13
DK256977A (da) 1978-03-30
AU514200B2 (en) 1981-01-29
CH625810A5 (en) 1981-10-15

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