BE859120A - Procede pour la preparation de steroides polyhalogenes utiles comme medicaments - Google Patents

Procede pour la preparation de steroides polyhalogenes utiles comme medicaments

Info

Publication number
BE859120A
BE859120A BE181243A BE181243A BE859120A BE 859120 A BE859120 A BE 859120A BE 181243 A BE181243 A BE 181243A BE 181243 A BE181243 A BE 181243A BE 859120 A BE859120 A BE 859120A
Authority
BE
Belgium
Prior art keywords
polyhalogenic
preparation
medicinal products
steroids useful
steroids
Prior art date
Application number
BE181243A
Other languages
English (en)
French (fr)
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of BE859120A publication Critical patent/BE859120A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C07J71/0015—Oxiranes at position 9(11)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BE181243A 1976-09-29 1977-09-28 Procede pour la preparation de steroides polyhalogenes utiles comme medicaments BE859120A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU75903A LU75903A1 (ja) 1976-09-29 1976-09-29

Publications (1)

Publication Number Publication Date
BE859120A true BE859120A (fr) 1978-03-28

Family

ID=19728370

Family Applications (1)

Application Number Title Priority Date Filing Date
BE181243A BE859120A (fr) 1976-09-29 1977-09-28 Procede pour la preparation de steroides polyhalogenes utiles comme medicaments

Country Status (24)

Country Link
JP (1) JPS5356652A (ja)
AT (3) AT363197B (ja)
AU (1) AU514200B2 (ja)
BE (1) BE859120A (ja)
CA (1) CA1101410A (ja)
CH (9) CH624967A5 (ja)
CY (1) CY1178A (ja)
DD (1) DD133150A5 (ja)
DE (1) DE2743069C2 (ja)
DK (1) DK146017C (ja)
ES (1) ES462763A1 (ja)
FR (1) FR2366311A1 (ja)
GB (1) GB1563638A (ja)
HK (1) HK16683A (ja)
HU (1) HU175218B (ja)
IE (1) IE46047B1 (ja)
IL (1) IL53012A (ja)
KE (1) KE3258A (ja)
LU (1) LU75903A1 (ja)
MY (1) MY8400092A (ja)
NL (1) NL7710089A (ja)
SE (1) SE436751B (ja)
SG (1) SG3383G (ja)
ZA (1) ZA775800B (ja)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL187577C (nl) * 1978-04-05 1991-11-18 Sibla Srl 3-acetoxy-9beta,11beta-epoxy-pregna-1,3,5-trienen, werkwijze voor de bereiding daarvan en werkwijze voor de bereiding van 6alfa-halogeen-pregna-1,4-dieen-3-onen.
DE3227312A1 (de) * 1982-07-19 1984-01-19 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 6,16-dimethylkortikoide, ihre herstellung und verwendung
EP0523132A1 (en) * 1990-03-27 1993-01-20 Schering Corporation PROCESS FOR 9$g(a)-HYDROXY STEROID DEHYDRATION
US5972922A (en) * 1990-06-11 1999-10-26 Alcon Laboratories, Inc. Steroids which inhibit angiogenesis
CA2473471A1 (en) 2001-11-29 2003-06-12 Taro Pharmaceuticals U.S.A., Inc. Method for the preparation of 6-alpha-fluoro corticosteroids
US8809307B2 (en) 2010-11-22 2014-08-19 Dow Pharmaceutical Sciences, Inc. Pharmaceutical formulations containing corticosteroids for topical administration
US11957753B2 (en) 2010-11-22 2024-04-16 Bausch Health Ireland Limited Pharmaceutical formulations containing corticosteroids for topical administration
AU2016279801B2 (en) 2015-06-18 2021-09-09 Valeant Pharmaceuticals North America Topical compositions comprising a corticosteroid and a retinoid for treating psoriasis

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB898292A (en) * 1959-03-18 1962-06-06 Upjohn Co Improvements in or relating to steroids and the manufacture thereof
US3644340A (en) * 1970-03-19 1972-02-22 Syntex Corp Preparation of 21-chloro steroids
US3992422A (en) * 1975-08-14 1976-11-16 Schering Corporation Process for the preparation of 21-halogeno-21-desoxy-17α-acyloxy-20-keto-pregnenes

Also Published As

Publication number Publication date
AT363197B (de) 1981-07-10
CH632521A5 (en) 1982-10-15
ZA775800B (en) 1978-08-30
IE46047L (en) 1978-03-29
FR2366311A1 (fr) 1978-04-28
CA1101410A (en) 1981-05-19
DK146017C (da) 1983-10-24
JPS5356652A (en) 1978-05-23
CH625809A5 (en) 1981-10-15
CY1178A (en) 1983-06-10
DK146017B (da) 1983-05-24
GB1563638A (en) 1980-03-26
HU175218B (hu) 1980-06-28
AU2914877A (en) 1979-04-05
FR2366311B1 (ja) 1982-12-03
DE2743069C2 (de) 1987-03-05
IL53012A (en) 1982-05-31
ES462763A1 (es) 1978-05-16
HK16683A (en) 1983-05-27
AT363203B (de) 1981-07-27
NL7710089A (nl) 1978-03-31
IE46047B1 (en) 1983-02-09
SG3383G (en) 1983-09-09
AT363202B (de) 1981-07-27
CH632279A5 (en) 1982-09-30
CH625808A5 (en) 1981-10-15
ATA691077A (de) 1980-12-15
CH631999A5 (en) 1982-09-15
CH624967A5 (en) 1981-08-31
SE7706673L (sv) 1978-03-30
ATA151379A (de) 1980-12-15
IL53012A0 (en) 1977-11-30
DE2743069A1 (de) 1978-03-30
JPS6214557B2 (ja) 1987-04-02
ATA151279A (de) 1980-12-15
CH631998A5 (en) 1982-09-15
KE3258A (en) 1983-03-04
SE436751B (sv) 1985-01-21
LU75903A1 (ja) 1978-05-16
MY8400092A (en) 1984-12-31
CH632000A5 (en) 1982-09-15
DD133150A5 (de) 1978-12-13
DK256977A (da) 1978-03-30
AU514200B2 (en) 1981-01-29
CH625810A5 (en) 1981-10-15

Similar Documents

Publication Publication Date Title
MC1336A1 (fr) Procede pour la preparation de compositions pharmaceutiques
BE846555A (fr) Procede pour la preparation de polyurethannes
FI792863A (fi) Foerfarande foer igaongsaettning av aongpanna med tvaongscirkulation
FR2283114A1 (fr) Procede de preparation de butanediols
BE885977A (fr) Procede pour la preparation de dithiazolyldisulfures
PT69132A (fr) Procede pour la preparation de systemes porteurs liposomiqes pour medicaments
BE859120A (fr) Procede pour la preparation de steroides polyhalogenes utiles comme medicaments
BE884153A (fr) Procede de preparation de compositions pharmaceutiques se desagregeant aisement
FR2274686A1 (fr) Procede pour la preparation de cholesterol esterase
BE842584A (fr) Procede pour la preparation de dihalogenures gemines
PT64718A (fr) Procede pour la preparation de phenyalcoylamines
BE880343A (fr) Procede de preparation de steroides
BE869833A (fr) 2,3-polymethylene-4-oxo-4h-pyrido(1,2-a) pyrimidines utiles comme medicaments et procede pour leur preparation
BE861137A (fr) Ortho-aminoacetophenones utiles comme medicaments et procede pour leur preparation
BE866588A (fr) Derives de 2-benzyl-perhydroazepines, procede pour leur preparation et application comme medicaments
BE824730A (fr) Procede pour la preparation de cyclopentandiones
FR2296628A1 (fr) Procede pour la preparation de chloroamino-s-triazines
FR2348174A1 (fr) Procede pour la preparation de dihalogenures gemines
BE830469A (fr) Procede de preparation d'acetoxybutanal
BE880139A (fr) Procede pour la preparation de chloro-amino-s-triazines
FR2378745B1 (fr) Procede pour la preparation de para-nitroso-diphenyl-hydroxylamines
RO79702A (ro) Procedeu pentru prepararea unei 3-di-n-propil-acetoxi-benzodiazepin-2-one
BE833953A (fr) Procede de preparation de pilules medicamenteuses
BE870138A (fr) Procede pour la preparation de 1-anthraquinonylhydrazines
PT66065B (fr) Procede pour la preparation de hydrocarbonetes

Legal Events

Date Code Title Description
RE20 Patent expired

Owner name: CIBA-GEIGY A.G.

Effective date: 19970928