NL7710089A - Werkwijze voor de bereiding van veelvoudig gehalogeneerde steroiden. - Google Patents

Werkwijze voor de bereiding van veelvoudig gehalogeneerde steroiden.

Info

Publication number
NL7710089A
NL7710089A NL7710089A NL7710089A NL7710089A NL 7710089 A NL7710089 A NL 7710089A NL 7710089 A NL7710089 A NL 7710089A NL 7710089 A NL7710089 A NL 7710089A NL 7710089 A NL7710089 A NL 7710089A
Authority
NL
Netherlands
Prior art keywords
preparing multiple
multiple halogenated
halogenated steroids
steroids
preparing
Prior art date
Application number
NL7710089A
Other languages
English (en)
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of NL7710089A publication Critical patent/NL7710089A/nl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J31/00Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/001Oxiranes
    • C07J71/0015Oxiranes at position 9(11)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NL7710089A 1976-09-29 1977-09-14 Werkwijze voor de bereiding van veelvoudig gehalogeneerde steroiden. NL7710089A (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU75903A LU75903A1 (nl) 1976-09-29 1976-09-29

Publications (1)

Publication Number Publication Date
NL7710089A true NL7710089A (nl) 1978-03-31

Family

ID=19728370

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7710089A NL7710089A (nl) 1976-09-29 1977-09-14 Werkwijze voor de bereiding van veelvoudig gehalogeneerde steroiden.

Country Status (24)

Country Link
JP (1) JPS5356652A (nl)
AT (3) AT363197B (nl)
AU (1) AU514200B2 (nl)
BE (1) BE859120A (nl)
CA (1) CA1101410A (nl)
CH (9) CH624967A5 (nl)
CY (1) CY1178A (nl)
DD (1) DD133150A5 (nl)
DE (1) DE2743069A1 (nl)
DK (1) DK146017C (nl)
ES (1) ES462763A1 (nl)
FR (1) FR2366311A1 (nl)
GB (1) GB1563638A (nl)
HK (1) HK16683A (nl)
HU (1) HU175218B (nl)
IE (1) IE46047B1 (nl)
IL (1) IL53012A (nl)
KE (1) KE3258A (nl)
LU (1) LU75903A1 (nl)
MY (1) MY8400092A (nl)
NL (1) NL7710089A (nl)
SE (1) SE436751B (nl)
SG (1) SG3383G (nl)
ZA (1) ZA775800B (nl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL187577C (nl) * 1978-04-05 1991-11-18 Sibla Srl 3-acetoxy-9beta,11beta-epoxy-pregna-1,3,5-trienen, werkwijze voor de bereiding daarvan en werkwijze voor de bereiding van 6alfa-halogeen-pregna-1,4-dieen-3-onen.
DE3227312A1 (de) * 1982-07-19 1984-01-19 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 6,16-dimethylkortikoide, ihre herstellung und verwendung
JPH05501115A (ja) * 1990-03-27 1993-03-04 シェリング・コーポレーション 9α―ヒドロキシ ステロイドの脱水法
US5972922A (en) * 1990-06-11 1999-10-26 Alcon Laboratories, Inc. Steroids which inhibit angiogenesis
BR0214520A (pt) 2001-11-29 2006-05-30 Taro Pharmaceuticals Usa Inc método para a preparação de corticosteróides de 6alfa-fluoro
US8809307B2 (en) 2010-11-22 2014-08-19 Dow Pharmaceutical Sciences, Inc. Pharmaceutical formulations containing corticosteroids for topical administration
US11957753B2 (en) 2010-11-22 2024-04-16 Bausch Health Ireland Limited Pharmaceutical formulations containing corticosteroids for topical administration
CA2988577A1 (en) 2015-06-18 2016-12-22 Valeant Pharmaceuticals North America Topical compositions comprising a corticosteroid and a retinoid for treating psoriasis

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB898292A (en) * 1959-03-18 1962-06-06 Upjohn Co Improvements in or relating to steroids and the manufacture thereof
US3644340A (en) * 1970-03-19 1972-02-22 Syntex Corp Preparation of 21-chloro steroids
US3992422A (en) * 1975-08-14 1976-11-16 Schering Corporation Process for the preparation of 21-halogeno-21-desoxy-17α-acyloxy-20-keto-pregnenes

Also Published As

Publication number Publication date
ATA151379A (de) 1980-12-15
GB1563638A (en) 1980-03-26
CH625810A5 (en) 1981-10-15
DK146017B (da) 1983-05-24
CH632279A5 (en) 1982-09-30
AT363203B (de) 1981-07-27
SG3383G (en) 1983-09-09
JPS5356652A (en) 1978-05-23
DD133150A5 (de) 1978-12-13
DK256977A (da) 1978-03-30
AT363197B (de) 1981-07-10
AT363202B (de) 1981-07-27
ES462763A1 (es) 1978-05-16
DE2743069C2 (nl) 1987-03-05
JPS6214557B2 (nl) 1987-04-02
IE46047L (en) 1978-03-29
ZA775800B (en) 1978-08-30
ATA151279A (de) 1980-12-15
IL53012A0 (en) 1977-11-30
BE859120A (fr) 1978-03-28
AU514200B2 (en) 1981-01-29
AU2914877A (en) 1979-04-05
CH631999A5 (en) 1982-09-15
CY1178A (en) 1983-06-10
CH632521A5 (en) 1982-10-15
LU75903A1 (nl) 1978-05-16
DK146017C (da) 1983-10-24
KE3258A (en) 1983-03-04
SE436751B (sv) 1985-01-21
IE46047B1 (en) 1983-02-09
CA1101410A (en) 1981-05-19
DE2743069A1 (de) 1978-03-30
CH625808A5 (en) 1981-10-15
ATA691077A (de) 1980-12-15
CH625809A5 (en) 1981-10-15
FR2366311B1 (nl) 1982-12-03
IL53012A (en) 1982-05-31
CH631998A5 (en) 1982-09-15
CH624967A5 (en) 1981-08-31
FR2366311A1 (fr) 1978-04-28
CH632000A5 (en) 1982-09-15
HK16683A (en) 1983-05-27
SE7706673L (sv) 1978-03-30
HU175218B (hu) 1980-06-28
MY8400092A (en) 1984-12-31

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Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
A85 Still pending on 85-01-01
BC A request for examination has been filed
CNR Transfer of rights (patent application after its laying open for public inspection)

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BV The patent application has lapsed