BE859120A - Procede pour la preparation de steroides polyhalogenes utiles comme medicaments - Google Patents

Procede pour la preparation de steroides polyhalogenes utiles comme medicaments

Info

Publication number
BE859120A
BE859120A BE181243A BE181243A BE859120A BE 859120 A BE859120 A BE 859120A BE 181243 A BE181243 A BE 181243A BE 181243 A BE181243 A BE 181243A BE 859120 A BE859120 A BE 859120A
Authority
BE
Belgium
Prior art keywords
polyhalogenic
preparation
medicinal products
steroids useful
steroids
Prior art date
Application number
BE181243A
Other languages
English (en)
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of BE859120A publication Critical patent/BE859120A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C07J71/0015—Oxiranes at position 9(11)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BE181243A 1976-09-29 1977-09-28 Procede pour la preparation de steroides polyhalogenes utiles comme medicaments BE859120A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU75903A LU75903A1 (fr) 1976-09-29 1976-09-29

Publications (1)

Publication Number Publication Date
BE859120A true BE859120A (fr) 1978-03-28

Family

ID=19728370

Family Applications (1)

Application Number Title Priority Date Filing Date
BE181243A BE859120A (fr) 1976-09-29 1977-09-28 Procede pour la preparation de steroides polyhalogenes utiles comme medicaments

Country Status (24)

Country Link
JP (1) JPS5356652A (fr)
AT (3) AT363197B (fr)
AU (1) AU514200B2 (fr)
BE (1) BE859120A (fr)
CA (1) CA1101410A (fr)
CH (9) CH624967A5 (fr)
CY (1) CY1178A (fr)
DD (1) DD133150A5 (fr)
DE (1) DE2743069A1 (fr)
DK (1) DK146017C (fr)
ES (1) ES462763A1 (fr)
FR (1) FR2366311A1 (fr)
GB (1) GB1563638A (fr)
HK (1) HK16683A (fr)
HU (1) HU175218B (fr)
IE (1) IE46047B1 (fr)
IL (1) IL53012A (fr)
KE (1) KE3258A (fr)
LU (1) LU75903A1 (fr)
MY (1) MY8400092A (fr)
NL (1) NL7710089A (fr)
SE (1) SE436751B (fr)
SG (1) SG3383G (fr)
ZA (1) ZA775800B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL187577C (nl) * 1978-04-05 1991-11-18 Sibla Srl 3-acetoxy-9beta,11beta-epoxy-pregna-1,3,5-trienen, werkwijze voor de bereiding daarvan en werkwijze voor de bereiding van 6alfa-halogeen-pregna-1,4-dieen-3-onen.
DE3227312A1 (de) * 1982-07-19 1984-01-19 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 6,16-dimethylkortikoide, ihre herstellung und verwendung
WO1991014700A2 (fr) * 1990-03-27 1991-10-03 Schering Corporation PROCEDE DE DESHYDRATATION DE 9α-HYDROXY STEROIDES
US5972922A (en) * 1990-06-11 1999-10-26 Alcon Laboratories, Inc. Steroids which inhibit angiogenesis
CN1596241A (zh) 2001-11-29 2005-03-16 塔罗制药美国公司 6α－氟皮质甾类的制备方法
US8809307B2 (en) 2010-11-22 2014-08-19 Dow Pharmaceutical Sciences, Inc. Pharmaceutical formulations containing corticosteroids for topical administration
US11957753B2 (en) 2010-11-22 2024-04-16 Bausch Health Ireland Limited Pharmaceutical formulations containing corticosteroids for topical administration
ES2812451T3 (es) 2015-06-18 2021-03-17 Bausch Health Ireland Ltd Composiciones tópicas que comprenden un corticosteroide y un retinoide para tratar la psoriasis

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB898292A (en) * 1959-03-18 1962-06-06 Upjohn Co Improvements in or relating to steroids and the manufacture thereof
US3644340A (en) * 1970-03-19 1972-02-22 Syntex Corp Preparation of 21-chloro steroids
US3992422A (en) * 1975-08-14 1976-11-16 Schering Corporation Process for the preparation of 21-halogeno-21-desoxy-17α-acyloxy-20-keto-pregnenes

Also Published As

Publication number Publication date
CH632279A5 (en) 1982-09-30
CH625808A5 (en) 1981-10-15
ATA151279A (de) 1980-12-15
AT363202B (de) 1981-07-27
DE2743069A1 (de) 1978-03-30
DK146017C (da) 1983-10-24
ES462763A1 (es) 1978-05-16
ZA775800B (en) 1978-08-30
LU75903A1 (fr) 1978-05-16
IL53012A (en) 1982-05-31
ATA151379A (de) 1980-12-15
HK16683A (en) 1983-05-27
AU2914877A (en) 1979-04-05
IL53012A0 (en) 1977-11-30
IE46047B1 (en) 1983-02-09
CH624967A5 (en) 1981-08-31
DK146017B (da) 1983-05-24
CH625810A5 (en) 1981-10-15
CH632000A5 (en) 1982-09-15
CH632521A5 (en) 1982-10-15
DE2743069C2 (fr) 1987-03-05
CH631998A5 (en) 1982-09-15
AT363203B (de) 1981-07-27
SG3383G (en) 1983-09-09
SE7706673L (sv) 1978-03-30
CA1101410A (fr) 1981-05-19
KE3258A (en) 1983-03-04
SE436751B (sv) 1985-01-21
CH631999A5 (en) 1982-09-15
MY8400092A (en) 1984-12-31
IE46047L (en) 1978-03-29
HU175218B (hu) 1980-06-28
FR2366311A1 (fr) 1978-04-28
CY1178A (en) 1983-06-10
JPS5356652A (en) 1978-05-23
FR2366311B1 (fr) 1982-12-03
GB1563638A (en) 1980-03-26
AT363197B (de) 1981-07-10
DD133150A5 (de) 1978-12-13
DK256977A (da) 1978-03-30
JPS6214557B2 (fr) 1987-04-02
CH625809A5 (en) 1981-10-15
NL7710089A (nl) 1978-03-31
ATA691077A (de) 1980-12-15
AU514200B2 (en) 1981-01-29

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Legal Events

Date Code Title Description
RE20 Patent expired

Owner name: CIBA-GEIGY A.G.

Effective date: 19970928