SE436751B - Forfarande enligt krav 1 i patentet 7613920-3 (publ.nr 423903) for framstellning av 17alfa-acyloxi-9alfa, 21-dihalogen-11beta-hydroxi-6alfa-fluor-16beta-metyl-pregna-1,4-dien-3,20-dion-foreningar - Google Patents

Forfarande enligt krav 1 i patentet 7613920-3 (publ.nr 423903) for framstellning av 17alfa-acyloxi-9alfa, 21-dihalogen-11beta-hydroxi-6alfa-fluor-16beta-metyl-pregna-1,4-dien-3,20-dion-foreningar

Info

Publication number
SE436751B
SE436751B SE7706673A SE7706673A SE436751B SE 436751 B SE436751 B SE 436751B SE 7706673 A SE7706673 A SE 7706673A SE 7706673 A SE7706673 A SE 7706673A SE 436751 B SE436751 B SE 436751B
Authority
SE
Sweden
Prior art keywords
acyloxi
9alfa
6alfa
17alfa
16beta
Prior art date
Application number
SE7706673A
Other languages
English (en)
Swedish (sv)
Other versions
SE7706673L (sv
Inventor
J Kalvoda
G Anner
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of SE7706673L publication Critical patent/SE7706673L/
Publication of SE436751B publication Critical patent/SE436751B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J31/00Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/001Oxiranes
    • C07J71/0015Oxiranes at position 9(11)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SE7706673A 1976-09-29 1977-06-08 Forfarande enligt krav 1 i patentet 7613920-3 (publ.nr 423903) for framstellning av 17alfa-acyloxi-9alfa, 21-dihalogen-11beta-hydroxi-6alfa-fluor-16beta-metyl-pregna-1,4-dien-3,20-dion-foreningar SE436751B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU75903A LU75903A1 (fr) 1976-09-29 1976-09-29

Publications (2)

Publication Number Publication Date
SE7706673L SE7706673L (sv) 1978-03-30
SE436751B true SE436751B (sv) 1985-01-21

Family

ID=19728370

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7706673A SE436751B (sv) 1976-09-29 1977-06-08 Forfarande enligt krav 1 i patentet 7613920-3 (publ.nr 423903) for framstellning av 17alfa-acyloxi-9alfa, 21-dihalogen-11beta-hydroxi-6alfa-fluor-16beta-metyl-pregna-1,4-dien-3,20-dion-foreningar

Country Status (24)

Country Link
JP (1) JPS5356652A (fr)
AT (3) AT363197B (fr)
AU (1) AU514200B2 (fr)
BE (1) BE859120A (fr)
CA (1) CA1101410A (fr)
CH (9) CH624967A5 (fr)
CY (1) CY1178A (fr)
DD (1) DD133150A5 (fr)
DE (1) DE2743069C2 (fr)
DK (1) DK146017C (fr)
ES (1) ES462763A1 (fr)
FR (1) FR2366311A1 (fr)
GB (1) GB1563638A (fr)
HK (1) HK16683A (fr)
HU (1) HU175218B (fr)
IE (1) IE46047B1 (fr)
IL (1) IL53012A (fr)
KE (1) KE3258A (fr)
LU (1) LU75903A1 (fr)
MY (1) MY8400092A (fr)
NL (1) NL7710089A (fr)
SE (1) SE436751B (fr)
SG (1) SG3383G (fr)
ZA (1) ZA775800B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL187577C (nl) * 1978-04-05 1991-11-18 Sibla Srl 3-acetoxy-9beta,11beta-epoxy-pregna-1,3,5-trienen, werkwijze voor de bereiding daarvan en werkwijze voor de bereiding van 6alfa-halogeen-pregna-1,4-dieen-3-onen.
DE3227312A1 (de) * 1982-07-19 1984-01-19 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 6,16-dimethylkortikoide, ihre herstellung und verwendung
EP0523132A1 (fr) * 1990-03-27 1993-01-20 Schering Corporation PROCEDE DE DESHYDRATATION DE 9$g(a)-HYDROXY STEROIDES
US5972922A (en) * 1990-06-11 1999-10-26 Alcon Laboratories, Inc. Steroids which inhibit angiogenesis
CA2473471A1 (fr) 2001-11-29 2003-06-12 Taro Pharmaceuticals U.S.A., Inc. Procede relatif a l'elaboration de 6-alpha-fluorocorticosteroides
US8809307B2 (en) 2010-11-22 2014-08-19 Dow Pharmaceutical Sciences, Inc. Pharmaceutical formulations containing corticosteroids for topical administration
US11957753B2 (en) 2010-11-22 2024-04-16 Bausch Health Ireland Limited Pharmaceutical formulations containing corticosteroids for topical administration
AU2016279801B2 (en) 2015-06-18 2021-09-09 Valeant Pharmaceuticals North America Topical compositions comprising a corticosteroid and a retinoid for treating psoriasis

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB898292A (en) * 1959-03-18 1962-06-06 Upjohn Co Improvements in or relating to steroids and the manufacture thereof
US3644340A (en) * 1970-03-19 1972-02-22 Syntex Corp Preparation of 21-chloro steroids
US3992422A (en) * 1975-08-14 1976-11-16 Schering Corporation Process for the preparation of 21-halogeno-21-desoxy-17α-acyloxy-20-keto-pregnenes

Also Published As

Publication number Publication date
AT363197B (de) 1981-07-10
BE859120A (fr) 1978-03-28
CH632521A5 (en) 1982-10-15
ZA775800B (en) 1978-08-30
IE46047L (en) 1978-03-29
FR2366311A1 (fr) 1978-04-28
CA1101410A (fr) 1981-05-19
DK146017C (da) 1983-10-24
JPS5356652A (en) 1978-05-23
CH625809A5 (en) 1981-10-15
CY1178A (en) 1983-06-10
DK146017B (da) 1983-05-24
GB1563638A (en) 1980-03-26
HU175218B (hu) 1980-06-28
AU2914877A (en) 1979-04-05
FR2366311B1 (fr) 1982-12-03
DE2743069C2 (de) 1987-03-05
IL53012A (en) 1982-05-31
ES462763A1 (es) 1978-05-16
HK16683A (en) 1983-05-27
AT363203B (de) 1981-07-27
NL7710089A (nl) 1978-03-31
IE46047B1 (en) 1983-02-09
SG3383G (en) 1983-09-09
AT363202B (de) 1981-07-27
CH632279A5 (en) 1982-09-30
CH625808A5 (en) 1981-10-15
ATA691077A (de) 1980-12-15
CH631999A5 (en) 1982-09-15
CH624967A5 (en) 1981-08-31
SE7706673L (sv) 1978-03-30
ATA151379A (de) 1980-12-15
IL53012A0 (en) 1977-11-30
DE2743069A1 (de) 1978-03-30
JPS6214557B2 (fr) 1987-04-02
ATA151279A (de) 1980-12-15
CH631998A5 (en) 1982-09-15
KE3258A (en) 1983-03-04
LU75903A1 (fr) 1978-05-16
MY8400092A (en) 1984-12-31
CH632000A5 (en) 1982-09-15
DD133150A5 (de) 1978-12-13
DK256977A (da) 1978-03-30
AU514200B2 (en) 1981-01-29
CH625810A5 (en) 1981-10-15

Similar Documents

Publication Publication Date Title
IT1086515B (it) Composti complessati,procedimento per la loro preparazione e loro impiego
AR224095A1 (es) Procedimiento de preparacion de nuevos derivados de ditiol-1,2 tiona-3
SE431653B (sv) Forfarande for framstellning av 2,3-dihydro-imidazo/2,1-b/tiazolderivat
SE436570B (sv) Forfarande for framstellning av n-(5-tetrazolyl)-4-oxo-4h-pyrimido/2,1-b/-bensotiazol-3-karboxamider med anti-allergisk verkan
NO770366L (no) Fremgangsm}te for fremstilling av meta-aryloksy-benzaldehyder.
DK314677A (da) Fremgangsmade il fremstilling af tic13.
SE7701459L (sv) Forfarande for framstellning av nya derivat av 1,2-ditiol
NO151365C (no) Fremgangsmaate for fremstilling av 4-halogen-dihydropyran-derivater.
NO149428C (no) Fremgangsmaate for fremstilling av fysiologisk aktive prostaglandinderivater.
SE436751B (sv) Forfarande enligt krav 1 i patentet 7613920-3 (publ.nr 423903) for framstellning av 17alfa-acyloxi-9alfa, 21-dihalogen-11beta-hydroxi-6alfa-fluor-16beta-metyl-pregna-1,4-dien-3,20-dion-foreningar
RO78954A (fr) Procede pour la preparation des gamma-pyrones
NL7707086A (nl) Pyrazolo(1,5-c)chinazoline derivaten en werk- wijzen voor hun bereiding en toepassing.
IT1083440B (it) Procedimento per la fabbricazione di cerniere lampo
RO81681A (fr) Procede pour la preparation des 1,2,3-thiadiazole-3-in-5-iyidenuree
DK187577A (da) Fremgangsmade til fremstilling af 1,4-benzodioxsnderivater
AR216558A1 (es) Procedimiento de preparacion de 1,3-dihidro-3-(3',4',5'-trimetoxi-estiril)-6-metil-7-hidroxi-furo-(3,4,c)-piridina
SE436026B (sv) Forfarande for framstellning av 13,14-dehydroprostaglandiner
RO77295A (fr) Procede pour la preparation des oxycarbamates-n-sulphenyles
SE423813B (sv) Forfarande for framstellning av 1,5-disubstituerade pyrrolidoner med terapeutiska egenskaper
RO70629A (fr) Procede pour la preparation du 1,1-dioxyde d'acide 3,4-dihydro-2-methyle-4-oxo-2h-1,2-benzothiazine-3-carboxylique
SE7707125L (sv) Forfarande for framstellning av 7-(alfa-(2,3, - dihydro-2-oxo-1h- bensimidazol -1- ylkarbomyl-amino) arylacetamido ) cefalasporiner
DK131474B (da) Analogifremgangsmåde til fremstilling af 9alfa-halogen-11beta, 17alfa, 21-trihydroxy-16beta-metylpregna-1,4-dien-3,20-dion-21-adamantan-1'-karboxylater.
SE428922B (sv) Forfarande for framstellning av 13, 14-dihydro-11-dioxi-prostaglandiner
DK140728B (da) Fremgangsmåde til fremstilling af pregnanderivater.
SE7613411L (sv) Forfarande vid framstellning av n,n'-bis-tri-metylsilylkarbamid

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 7706673-6

Format of ref document f/p: F

NUG Patent has lapsed

Ref document number: 7706673-6

Format of ref document f/p: F