ZA775800B - Polyhalogenated steroids - Google Patents

Polyhalogenated steroids

Info

Publication number
ZA775800B
ZA775800B ZA00775800A ZA775800A ZA775800B ZA 775800 B ZA775800 B ZA 775800B ZA 00775800 A ZA00775800 A ZA 00775800A ZA 775800 A ZA775800 A ZA 775800A ZA 775800 B ZA775800 B ZA 775800B
Authority
ZA
South Africa
Prior art keywords
polyhalogenated
steroids
polyhalogenated steroids
Prior art date
Application number
ZA00775800A
Other languages
English (en)
Inventor
J Kalvoda
G Anner
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of ZA775800B publication Critical patent/ZA775800B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J31/00Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/001Oxiranes
    • C07J71/0015Oxiranes at position 9(11)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA00775800A 1976-09-29 1977-09-28 Polyhalogenated steroids ZA775800B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU75903A LU75903A1 (fr) 1976-09-29 1976-09-29

Publications (1)

Publication Number Publication Date
ZA775800B true ZA775800B (en) 1978-08-30

Family

ID=19728370

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00775800A ZA775800B (en) 1976-09-29 1977-09-28 Polyhalogenated steroids

Country Status (24)

Country Link
JP (1) JPS5356652A (fr)
AT (3) AT363197B (fr)
AU (1) AU514200B2 (fr)
BE (1) BE859120A (fr)
CA (1) CA1101410A (fr)
CH (9) CH624967A5 (fr)
CY (1) CY1178A (fr)
DD (1) DD133150A5 (fr)
DE (1) DE2743069C2 (fr)
DK (1) DK146017C (fr)
ES (1) ES462763A1 (fr)
FR (1) FR2366311A1 (fr)
GB (1) GB1563638A (fr)
HK (1) HK16683A (fr)
HU (1) HU175218B (fr)
IE (1) IE46047B1 (fr)
IL (1) IL53012A (fr)
KE (1) KE3258A (fr)
LU (1) LU75903A1 (fr)
MY (1) MY8400092A (fr)
NL (1) NL7710089A (fr)
SE (1) SE436751B (fr)
SG (1) SG3383G (fr)
ZA (1) ZA775800B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL187577C (nl) * 1978-04-05 1991-11-18 Sibla Srl 3-acetoxy-9beta,11beta-epoxy-pregna-1,3,5-trienen, werkwijze voor de bereiding daarvan en werkwijze voor de bereiding van 6alfa-halogeen-pregna-1,4-dieen-3-onen.
DE3227312A1 (de) * 1982-07-19 1984-01-19 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 6,16-dimethylkortikoide, ihre herstellung und verwendung
AU7556291A (en) * 1990-03-27 1991-10-21 Schering Corporation Process for 9alpha-hydroxy steroid dehydration
US5972922A (en) * 1990-06-11 1999-10-26 Alcon Laboratories, Inc. Steroids which inhibit angiogenesis
CA2473471A1 (fr) 2001-11-29 2003-06-12 Taro Pharmaceuticals U.S.A., Inc. Procede relatif a l'elaboration de 6-alpha-fluorocorticosteroides
US11957753B2 (en) 2010-11-22 2024-04-16 Bausch Health Ireland Limited Pharmaceutical formulations containing corticosteroids for topical administration
US8809307B2 (en) 2010-11-22 2014-08-19 Dow Pharmaceutical Sciences, Inc. Pharmaceutical formulations containing corticosteroids for topical administration
WO2016205001A1 (fr) 2015-06-18 2016-12-22 Valeant Pharmaceuticals North America Compositions topiques comprenant un corticostéroïde et un rétinoïde pour le traitement du psoriasis
US11311482B2 (en) 2017-05-12 2022-04-26 Bausch Health Us, Llc Topical compositions and methods for treating skin diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB898292A (en) * 1959-03-18 1962-06-06 Upjohn Co Improvements in or relating to steroids and the manufacture thereof
US3644340A (en) * 1970-03-19 1972-02-22 Syntex Corp Preparation of 21-chloro steroids
US3992422A (en) * 1975-08-14 1976-11-16 Schering Corporation Process for the preparation of 21-halogeno-21-desoxy-17α-acyloxy-20-keto-pregnenes

Also Published As

Publication number Publication date
ES462763A1 (es) 1978-05-16
HK16683A (en) 1983-05-27
SG3383G (en) 1983-09-09
CH632279A5 (en) 1982-09-30
DD133150A5 (de) 1978-12-13
DK256977A (da) 1978-03-30
IL53012A (en) 1982-05-31
JPS6214557B2 (fr) 1987-04-02
FR2366311B1 (fr) 1982-12-03
CY1178A (en) 1983-06-10
ATA691077A (de) 1980-12-15
AT363197B (de) 1981-07-10
DE2743069C2 (de) 1987-03-05
MY8400092A (en) 1984-12-31
BE859120A (fr) 1978-03-28
NL7710089A (nl) 1978-03-31
AT363202B (de) 1981-07-27
DE2743069A1 (de) 1978-03-30
CH632521A5 (en) 1982-10-15
KE3258A (en) 1983-03-04
SE436751B (sv) 1985-01-21
FR2366311A1 (fr) 1978-04-28
CH625808A5 (en) 1981-10-15
AT363203B (de) 1981-07-27
ATA151379A (de) 1980-12-15
LU75903A1 (fr) 1978-05-16
AU514200B2 (en) 1981-01-29
CH625809A5 (en) 1981-10-15
IE46047L (en) 1978-03-29
CH631999A5 (en) 1982-09-15
HU175218B (hu) 1980-06-28
ATA151279A (de) 1980-12-15
CH632000A5 (en) 1982-09-15
SE7706673L (sv) 1978-03-30
IE46047B1 (en) 1983-02-09
DK146017B (da) 1983-05-24
CH631998A5 (en) 1982-09-15
IL53012A0 (en) 1977-11-30
AU2914877A (en) 1979-04-05
CH625810A5 (en) 1981-10-15
CH624967A5 (en) 1981-08-31
CA1101410A (fr) 1981-05-19
JPS5356652A (en) 1978-05-23
DK146017C (da) 1983-10-24
GB1563638A (en) 1980-03-26

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