LT3219321T - Stromos kamieninės ląstelės, kilusios iš riebalinio audinio, skirtos panaudoti gydant atsparias gydymui kompleksines perianalines fistules krono ligos atveju - Google Patents

Stromos kamieninės ląstelės, kilusios iš riebalinio audinio, skirtos panaudoti gydant atsparias gydymui kompleksines perianalines fistules krono ligos atveju

Info

Publication number
LT3219321T
LT3219321T LTEP17160932.4T LT17160932T LT3219321T LT 3219321 T LT3219321 T LT 3219321T LT 17160932 T LT17160932 T LT 17160932T LT 3219321 T LT3219321 T LT 3219321T
Authority
LT
Lithuania
Prior art keywords
crohn
disease
stem cells
adipose tissue
derived stromal
Prior art date
Application number
LTEP17160932.4T
Other languages
English (en)
Lithuanian (lt)
Inventor
Eduardo BRAVO
Maria PASCUAL
Original Assignee
Takeda Pharmaceutical Company Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical Company Limited filed Critical Takeda Pharmaceutical Company Limited
Publication of LT3219321T publication Critical patent/LT3219321T/lt

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • C12N5/0667Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/35Fat tissue; Adipocytes; Stromal cells; Connective tissues
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0653Adipocytes; Adipose tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
LTEP17160932.4T 2016-03-14 2017-03-14 Stromos kamieninės ląstelės, kilusios iš riebalinio audinio, skirtos panaudoti gydant atsparias gydymui kompleksines perianalines fistules krono ligos atveju LT3219321T (lt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1604304.4A GB201604304D0 (en) 2016-03-14 2016-03-14 Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease

Publications (1)

Publication Number Publication Date
LT3219321T true LT3219321T (lt) 2022-05-10

Family

ID=55952284

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP17160932.4T LT3219321T (lt) 2016-03-14 2017-03-14 Stromos kamieninės ląstelės, kilusios iš riebalinio audinio, skirtos panaudoti gydant atsparias gydymui kompleksines perianalines fistules krono ligos atveju

Country Status (27)

Country Link
US (3) US10357518B2 (enExample)
EP (2) EP3219321B1 (enExample)
JP (2) JP6931656B2 (enExample)
KR (1) KR102277789B1 (enExample)
CN (2) CN108883135B (enExample)
AU (1) AU2017232718B2 (enExample)
BE (1) BE1024781B1 (enExample)
CA (1) CA3017694C (enExample)
CY (1) CY1125513T1 (enExample)
DE (1) DE102017002458B4 (enExample)
DK (1) DK3219321T3 (enExample)
ES (2) ES2911718T3 (enExample)
FR (1) FR3048614B1 (enExample)
GB (2) GB201604304D0 (enExample)
HR (1) HRP20220539T1 (enExample)
HU (1) HUE058739T2 (enExample)
IL (2) IL261730B2 (enExample)
LT (1) LT3219321T (enExample)
MX (1) MX2018010699A (enExample)
NL (1) NL2018512B1 (enExample)
NO (1) NO345415B1 (enExample)
PL (1) PL3219321T3 (enExample)
RS (1) RS63163B1 (enExample)
RU (1) RU2742308C2 (enExample)
SG (2) SG11201807404XA (enExample)
SI (1) SI3219321T1 (enExample)
WO (1) WO2017158509A1 (enExample)

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MX2021010221A (es) * 2019-02-27 2021-09-21 Takeda Pharmaceuticals Co Poblaciones mejoradas de celulas germinales para terapia alogenica.
KR20220152240A (ko) * 2020-03-11 2022-11-15 메조블라스트 인터내셔널 에스에이알엘 염증성 장 질환 ii의 치료 방법
EP4117691A1 (en) * 2020-03-11 2023-01-18 Mesoblast International Sàrl Method for treating inflammatory bowel disease i
CN111481573A (zh) * 2020-03-26 2020-08-04 卡替(上海)生物技术股份有限公司 牙髓间充质干细胞在制备克罗恩病治疗药物中的用途
AU2021388154A1 (en) * 2020-11-25 2023-06-22 Flagship Pioneering Innovations Vi, Llc Adipogenic cell compositions and methods
WO2023230524A1 (en) * 2022-05-25 2023-11-30 Flagship Pioneering Innovations Vi, Llc Compositions of secretory and/or catalytic cells and methods using the same

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US10357518B2 (en) 2019-07-23
EP4074322A1 (en) 2022-10-19
JP2021119789A (ja) 2021-08-19
WO2017158509A1 (en) 2017-09-21
IL298107B2 (en) 2024-02-01
ES2681774B1 (es) 2019-12-26
ES2681774A1 (es) 2018-09-14
HRP20220539T1 (hr) 2022-06-10
GB2548490A (en) 2017-09-20
DK3219321T3 (da) 2022-04-25
IL298107A (en) 2023-01-01
BR112018068493A8 (pt) 2022-06-28
AU2017232718A1 (en) 2018-10-04
RS63163B1 (sr) 2022-05-31
BE1024781A1 (de) 2018-06-27
RU2018131519A3 (enExample) 2020-07-10
DE102017002458A1 (de) 2017-09-14
CY1125513T1 (el) 2024-12-13
GB201704065D0 (en) 2017-04-26
CA3017694C (en) 2024-02-27
RU2018131519A (ru) 2020-04-15
FR3048614B1 (fr) 2020-02-21
CN115569151A (zh) 2023-01-06
NL2018512B1 (en) 2017-09-07
SI3219321T1 (sl) 2022-05-31
EP3219321A1 (en) 2017-09-20
JP2019508455A (ja) 2019-03-28
FR3048614A1 (enExample) 2017-09-15
IL298107B1 (en) 2023-10-01
NO345415B1 (en) 2021-01-18
MX2018010699A (es) 2019-01-14
JP6931656B2 (ja) 2021-09-08
BR112018068493A2 (pt) 2019-01-22
US20220249574A1 (en) 2022-08-11
EP3219321B1 (en) 2022-03-30
GB201604304D0 (en) 2016-04-27
HUE058739T2 (hu) 2022-09-28
CN108883135B (zh) 2022-11-04
SG11201807404XA (en) 2018-09-27
KR20180120261A (ko) 2018-11-05
GB2548490B (en) 2020-09-02
RU2742308C2 (ru) 2021-02-04
US11273182B2 (en) 2022-03-15
US12213998B2 (en) 2025-02-04
PL3219321T3 (pl) 2022-05-30
US20170258851A1 (en) 2017-09-14
IL261730B1 (en) 2024-01-01
NO20170376A1 (en) 2017-09-15
KR102277789B1 (ko) 2021-07-15
IL261730B2 (en) 2024-05-01
AU2017232718B2 (en) 2024-01-18
NL2018512A (en) 2017-03-30
CN108883135A (zh) 2018-11-23
US20190381106A1 (en) 2019-12-19
DE102017002458B4 (de) 2019-04-25
BE1024781B1 (de) 2018-07-02
CA3017694A1 (en) 2017-09-21
IL261730A (en) 2018-10-31
SG10202008992YA (en) 2020-10-29
ES2911718T3 (es) 2022-05-20

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