DE102017002458B4 - Von adipösem gewebe stammende stromale stammzellen zur verwendung bei der behandlung behandlungsresistenter komplexer perianalfisteln bei morbus crohn - Google Patents
Von adipösem gewebe stammende stromale stammzellen zur verwendung bei der behandlung behandlungsresistenter komplexer perianalfisteln bei morbus crohn Download PDFInfo
- Publication number
- DE102017002458B4 DE102017002458B4 DE102017002458.8A DE102017002458A DE102017002458B4 DE 102017002458 B4 DE102017002458 B4 DE 102017002458B4 DE 102017002458 A DE102017002458 A DE 102017002458A DE 102017002458 B4 DE102017002458 B4 DE 102017002458B4
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- adipose tissue
- fistula
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- cells
- stromal stem
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/35—Fat tissue; Adipocytes; Stromal cells; Connective tissues
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0653—Adipocytes; Adipose tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Developmental Biology & Embryology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Rheumatology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1604304.4 | 2016-03-14 | ||
| GBGB1604304.4A GB201604304D0 (en) | 2016-03-14 | 2016-03-14 | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE102017002458A1 DE102017002458A1 (de) | 2017-09-14 |
| DE102017002458B4 true DE102017002458B4 (de) | 2019-04-25 |
Family
ID=55952284
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE102017002458.8A Active DE102017002458B4 (de) | 2016-03-14 | 2017-03-14 | Von adipösem gewebe stammende stromale stammzellen zur verwendung bei der behandlung behandlungsresistenter komplexer perianalfisteln bei morbus crohn |
Country Status (27)
| Country | Link |
|---|---|
| US (3) | US10357518B2 (enExample) |
| EP (2) | EP4074322A1 (enExample) |
| JP (2) | JP6931656B2 (enExample) |
| KR (1) | KR102277789B1 (enExample) |
| CN (2) | CN108883135B (enExample) |
| AU (1) | AU2017232718B2 (enExample) |
| BE (1) | BE1024781B1 (enExample) |
| CA (1) | CA3017694C (enExample) |
| CY (1) | CY1125513T1 (enExample) |
| DE (1) | DE102017002458B4 (enExample) |
| DK (1) | DK3219321T3 (enExample) |
| ES (2) | ES2681774B1 (enExample) |
| FR (1) | FR3048614B1 (enExample) |
| GB (2) | GB201604304D0 (enExample) |
| HR (1) | HRP20220539T1 (enExample) |
| HU (1) | HUE058739T2 (enExample) |
| IL (2) | IL298107B2 (enExample) |
| LT (1) | LT3219321T (enExample) |
| MX (1) | MX2018010699A (enExample) |
| NL (1) | NL2018512B1 (enExample) |
| NO (1) | NO345415B1 (enExample) |
| PL (1) | PL3219321T3 (enExample) |
| RS (1) | RS63163B1 (enExample) |
| RU (1) | RU2742308C2 (enExample) |
| SG (2) | SG11201807404XA (enExample) |
| SI (1) | SI3219321T1 (enExample) |
| WO (1) | WO2017158509A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060045872A1 (en) | 2004-08-25 | 2006-03-02 | Universidad Autonoma De Madrid Ciudad Universitaria de Cantoblanco | Use of adipose tissue-derived stromal stem cells in treating fistula |
| GB201604304D0 (en) * | 2016-03-14 | 2016-04-27 | Tigenix S A U | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
| AU2018244922A1 (en) | 2017-03-30 | 2019-09-12 | Biora Therapeutics, Inc. | Treatment of a disease of the gastrointestinal tract with live biotherapeutics |
| MX2021010221A (es) * | 2019-02-27 | 2021-09-21 | Takeda Pharmaceuticals Co | Poblaciones mejoradas de celulas germinales para terapia alogenica. |
| AU2021234104A1 (en) * | 2020-03-11 | 2022-09-29 | Mesoblast International Sàrl | Method for treating inflammatory bowel disease I |
| US20230104108A1 (en) * | 2020-03-11 | 2023-04-06 | Mesoblast International Sárl | Method for treating inflammatory bowel disease ii |
| CN111481573A (zh) * | 2020-03-26 | 2020-08-04 | 卡替(上海)生物技术股份有限公司 | 牙髓间充质干细胞在制备克罗恩病治疗药物中的用途 |
| WO2022115609A1 (en) * | 2020-11-25 | 2022-06-02 | Flagship Pioneering, Inc. | Adipogenic cell compositions and methods |
| WO2023230524A1 (en) * | 2022-05-25 | 2023-11-30 | Flagship Pioneering Innovations Vi, Llc | Compositions of secretory and/or catalytic cells and methods using the same |
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2016
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2017
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- 2017-03-14 RU RU2018131519A patent/RU2742308C2/ru active
- 2017-03-14 BE BE2017/5156A patent/BE1024781B1/de active IP Right Grant
- 2017-03-14 SG SG10202008992YA patent/SG10202008992YA/en unknown
- 2017-03-14 SI SI201731122T patent/SI3219321T1/sl unknown
- 2017-03-14 RS RS20220355A patent/RS63163B1/sr unknown
- 2017-03-14 HU HUE17160932A patent/HUE058739T2/hu unknown
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- 2017-03-14 MX MX2018010699A patent/MX2018010699A/es unknown
- 2017-03-14 AU AU2017232718A patent/AU2017232718B2/en active Active
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- 2017-03-14 NO NO20170376A patent/NO345415B1/en unknown
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2019
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2021
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