ATE482725T1 - Auf stammzellen, vorläuferzellen oder targetzellen basierende behandlung von multiorganversagen. - Google Patents
Auf stammzellen, vorläuferzellen oder targetzellen basierende behandlung von multiorganversagen.Info
- Publication number
- ATE482725T1 ATE482725T1 AT04758676T AT04758676T ATE482725T1 AT E482725 T1 ATE482725 T1 AT E482725T1 AT 04758676 T AT04758676 T AT 04758676T AT 04758676 T AT04758676 T AT 04758676T AT E482725 T1 ATE482725 T1 AT E482725T1
- Authority
- AT
- Austria
- Prior art keywords
- cell
- progressor
- organ failure
- based treatment
- target
- Prior art date
Links
- 210000004027 cell Anatomy 0.000 title abstract 3
- 208000034486 Multi-organ failure Diseases 0.000 title abstract 2
- 208000029744 multiple organ dysfunction syndrome Diseases 0.000 title abstract 2
- 210000000130 stem cell Anatomy 0.000 title 1
- 208000009304 Acute Kidney Injury Diseases 0.000 abstract 1
- 208000033626 Renal failure acute Diseases 0.000 abstract 1
- 201000011040 acute kidney failure Diseases 0.000 abstract 1
- 208000012998 acute renal failure Diseases 0.000 abstract 1
- 208000020832 chronic kidney disease Diseases 0.000 abstract 1
- 208000022831 chronic renal failure syndrome Diseases 0.000 abstract 1
- 230000004064 dysfunction Effects 0.000 abstract 1
- 230000003394 haemopoietic effect Effects 0.000 abstract 1
- 210000003566 hemangioblast Anatomy 0.000 abstract 1
- 210000003958 hematopoietic stem cell Anatomy 0.000 abstract 1
- 210000003734 kidney Anatomy 0.000 abstract 1
- 210000002901 mesenchymal stem cell Anatomy 0.000 abstract 1
- 230000004768 organ dysfunction Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 230000029663 wound healing Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/22—Urine; Urinary tract, e.g. kidney or bladder; Intraglomerular mesangial cells; Renal mesenchymal cells; Adrenal gland
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/44—Vessels; Vascular smooth muscle cells; Endothelial cells; Endothelial progenitor cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/195—Chemokines, e.g. RANTES
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Developmental Biology & Embryology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45955403P | 2003-04-01 | 2003-04-01 | |
| US47517803P | 2003-06-02 | 2003-06-02 | |
| PCT/US2004/009922 WO2004090112A2 (en) | 2003-04-01 | 2004-03-31 | Stem-cell, precursor cell, or target cell-based treatment of multi-organ failure and renal dysfunction |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE482725T1 true ATE482725T1 (de) | 2010-10-15 |
Family
ID=33162210
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04758676T ATE482725T1 (de) | 2003-04-01 | 2004-03-31 | Auf stammzellen, vorläuferzellen oder targetzellen basierende behandlung von multiorganversagen. |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US8603462B2 (de) |
| EP (3) | EP2263698A1 (de) |
| AT (1) | ATE482725T1 (de) |
| AU (2) | AU2004227342B2 (de) |
| CA (3) | CA2809195C (de) |
| DE (1) | DE602004029337D1 (de) |
| WO (1) | WO2004090112A2 (de) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE482725T1 (de) | 2003-04-01 | 2010-10-15 | Us Dept Of Veteran S Affaires | Auf stammzellen, vorläuferzellen oder targetzellen basierende behandlung von multiorganversagen. |
| US20060045872A1 (en) | 2004-08-25 | 2006-03-02 | Universidad Autonoma De Madrid Ciudad Universitaria de Cantoblanco | Use of adipose tissue-derived stromal stem cells in treating fistula |
| BRPI0520280A2 (pt) * | 2005-05-10 | 2009-04-28 | Us Of America Dept Of Veteran | terapia de disfunÇÕes renais e falÊncia méltipla de àrgços com cÉlulas-tronco mesenquimais e meio condicionado por exposiÇço a cÉlulas-tronco mesenquimais |
| MX342474B (es) | 2005-09-23 | 2016-09-30 | Cellerix Sl | Poblaciones celulares con actividad inmunoreguladora, método de aislamiento y usos. |
| WO2008036349A2 (en) | 2006-09-19 | 2008-03-27 | Insugen, Llc | Fused stem cells useful for the treatment of diabetes and methods thereof |
| WO2008060788A2 (en) | 2006-10-11 | 2008-05-22 | The General Hospital Corporation | Compositions, methods, and devices for treating liver disease |
| US20080125490A1 (en) * | 2006-11-03 | 2008-05-29 | My Svensson | Treatment and prevention of cardiovascular disease in patients with chronic kidney disease by administering Omega-3 Fatty Acids |
| WO2008109674A2 (en) | 2007-03-05 | 2008-09-12 | Caridianbct, Inc. | Cell expansion system and methods of use |
| US20110020291A1 (en) * | 2007-11-17 | 2011-01-27 | Debrabrata Banerjee | Use of stem cells for wound healing |
| WO2009085216A2 (en) | 2007-12-20 | 2009-07-09 | Squicor | Compositions and methods for detecting or elimninating senescent cells to diagnose or treat disease |
| US20090291061A1 (en) * | 2008-05-21 | 2009-11-26 | Riordan Neil H | Stem cell therapy for blood vessel degeneration |
| GB0814249D0 (en) * | 2008-08-04 | 2008-09-10 | Cellerix Sa | Uses of mesenchymal stem cells |
| US20100111908A1 (en) * | 2008-11-03 | 2010-05-06 | Fangming Lin | Induction of Renal Cells for Treatment of Kidney Disease |
| JP2013506681A (ja) * | 2009-10-02 | 2013-02-28 | バクスター・インターナショナル・インコーポレイテッド | 腎損傷の処置における使用のための造血幹細胞 |
| US20120269779A1 (en) * | 2009-10-30 | 2012-10-25 | Allocure, Inc. | Mesenchymal stromal cell populations and methods of using same |
| US8822218B2 (en) * | 2009-12-04 | 2014-09-02 | Stem Cell & Regenerative Medicine International, Inc. | Method of generating natural killer cells and dendritic cells from human embryonic stem cell-derived hemangioblasts |
| US9057045B2 (en) | 2009-12-29 | 2015-06-16 | Terumo Bct, Inc. | Method of loading and distributing cells in a bioreactor of a cell expansion system |
| CN103180435A (zh) * | 2010-08-31 | 2013-06-26 | 库克通用生物技术有限责任公司 | 用于治疗动物疾病的全身的同种异体干细胞疗法 |
| WO2012040408A2 (en) * | 2010-09-23 | 2012-03-29 | Children's Medical Center Corporation | Engineered vascular adipose tissue |
| WO2012048275A2 (en) | 2010-10-08 | 2012-04-12 | Caridianbct, Inc. | Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system |
| US20130287747A1 (en) * | 2012-04-30 | 2013-10-31 | Allocure, Inc. | Methods of Treating Acute Kidney Injury Using Mesenchymal Stem Cells |
| CN104540933A (zh) | 2012-08-20 | 2015-04-22 | 泰尔茂比司特公司 | 在细胞扩增系统的生物反应器中加载和分配细胞的方法 |
| CN105793411B (zh) | 2013-11-16 | 2018-04-17 | 泰尔茂比司特公司 | 生物反应器中的细胞扩增 |
| JP2015160820A (ja) * | 2014-02-26 | 2015-09-07 | 株式会社Clio | 慢性腎障害治療のための多能性幹細胞 |
| JP6783143B2 (ja) | 2014-03-25 | 2020-11-11 | テルモ ビーシーティー、インコーポレーテッド | 培地の受動的補充 |
| WO2015164808A1 (en) | 2014-04-24 | 2015-10-29 | Terumo Bct, Inc. | Measuring flow rate |
| JP6779866B2 (ja) | 2014-06-13 | 2020-11-04 | チルドレンズ メディカル センター コーポレイション | ミトコンドリアを単離するための製品および方法 |
| US20160090569A1 (en) | 2014-09-26 | 2016-03-31 | Terumo Bct, Inc. | Scheduled Feed |
| WO2017004592A1 (en) | 2015-07-02 | 2017-01-05 | Terumo Bct, Inc. | Cell growth with mechanical stimuli |
| WO2017095946A1 (en) | 2015-11-30 | 2017-06-08 | Flagship Pioneering, Inc. | Methods and compositions relating to chondrisomes |
| FI4272834T3 (fi) * | 2016-01-15 | 2025-12-05 | Childrens Medical Ct Corp | Mitokondrioiden ja yhdistettyjen mitokondriaalisten aineiden terapeuttinen käyttö |
| KR20180102661A (ko) | 2016-01-21 | 2018-09-17 | 에이비티 홀딩 컴퍼니 | 상처 치유를 위한 줄기 세포 |
| GB201604304D0 (en) | 2016-03-14 | 2016-04-27 | Tigenix S A U | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
| US11965175B2 (en) | 2016-05-25 | 2024-04-23 | Terumo Bct, Inc. | Cell expansion |
| US11685883B2 (en) | 2016-06-07 | 2023-06-27 | Terumo Bct, Inc. | Methods and systems for coating a cell growth surface |
| US11104874B2 (en) | 2016-06-07 | 2021-08-31 | Terumo Bct, Inc. | Coating a bioreactor |
| US11629332B2 (en) | 2017-03-31 | 2023-04-18 | Terumo Bct, Inc. | Cell expansion |
| US12234441B2 (en) | 2017-03-31 | 2025-02-25 | Terumo Bct, Inc. | Cell expansion |
| US11624046B2 (en) | 2017-03-31 | 2023-04-11 | Terumo Bct, Inc. | Cell expansion |
| CN108646035B (zh) * | 2018-05-18 | 2021-06-11 | 北京亦科诺生物科技有限公司 | 胰岛素样生长因子1的新应用 |
| JP2022517531A (ja) * | 2019-01-18 | 2022-03-09 | アブラハム ジェイ アンド フィリス カッツ コード ブラッド ファウンデーション | 神経学的疾患のための二重幹細胞治療 |
| EP4076535A4 (de) * | 2019-12-19 | 2024-04-17 | University of Miami | Verabreichung von stammzellen |
| WO2021226373A2 (en) | 2020-05-08 | 2021-11-11 | Gallant Pet, Inc. | Uterine-derived regenerative cell compositions and uses thereof |
| EP4314244B1 (de) | 2021-03-23 | 2025-07-23 | Terumo BCT, Inc. | Zellerfassung und -erweiterung |
| US12152699B2 (en) | 2022-02-28 | 2024-11-26 | Terumo Bct, Inc. | Multiple-tube pinch valve assembly |
| USD1099116S1 (en) | 2022-09-01 | 2025-10-21 | Terumo Bct, Inc. | Display screen or portion thereof with a graphical user interface for displaying cell culture process steps and measurements of an associated bioreactor device |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US459554A (en) | 1891-09-15 | Fence-wire stretcher | ||
| US475178A (en) | 1892-05-17 | Electrical forge | ||
| US5486359A (en) * | 1990-11-16 | 1996-01-23 | Osiris Therapeutics, Inc. | Human mesenchymal stem cells |
| US5811094A (en) * | 1990-11-16 | 1998-09-22 | Osiris Therapeutics, Inc. | Connective tissue regeneration using human mesenchymal stem cell preparations |
| US5837539A (en) * | 1990-11-16 | 1998-11-17 | Osiris Therapeutics, Inc. | Monoclonal antibodies for human mesenchymal stem cells |
| US5226914A (en) * | 1990-11-16 | 1993-07-13 | Caplan Arnold I | Method for treating connective tissue disorders |
| US5733542A (en) * | 1990-11-16 | 1998-03-31 | Haynesworth; Stephen E. | Enhancing bone marrow engraftment using MSCS |
| US6010696A (en) * | 1990-11-16 | 2000-01-04 | Osiris Therapeutics, Inc. | Enhancing hematopoietic progenitor cell engraftment using mesenchymal stem cells |
| US5197985A (en) * | 1990-11-16 | 1993-03-30 | Caplan Arnold I | Method for enhancing the implantation and differentiation of marrow-derived mesenchymal cells |
| US5876708A (en) * | 1992-02-19 | 1999-03-02 | The General Hospital Corporation | Allogeneic and xenogeneic transplantation |
| US5591625A (en) * | 1993-11-24 | 1997-01-07 | Case Western Reserve University | Transduced mesenchymal stem cells |
| CA2192103C (en) * | 1994-06-06 | 2002-02-05 | Arnold I. Caplan | Biomatrix for tissue regeneration |
| US6174333B1 (en) * | 1994-06-06 | 2001-01-16 | Osiris Therapeutics, Inc. | Biomatrix for soft tissue regeneration using mesenchymal stem cells |
| US5736396A (en) * | 1995-01-24 | 1998-04-07 | Case Western Reserve University | Lineage-directed induction of human mesenchymal stem cell differentiation |
| US5643736A (en) * | 1995-02-06 | 1997-07-01 | Osiris Therapeutics, Inc. | Monoclonal antibodies for human osteogenic cell surface antigens |
| US5908782A (en) * | 1995-06-05 | 1999-06-01 | Osiris Therapeutics, Inc. | Chemically defined medium for human mesenchymal stem cells |
| ATE288480T1 (de) * | 1995-11-16 | 2005-02-15 | Univ Case Western Reserve | Chondrogene in vitro induktion von menschlichen mensenchymalen stammzellen |
| US6482231B1 (en) * | 1995-11-20 | 2002-11-19 | Giovanni Abatangelo | Biological material for the repair of connective tissue defects comprising mesenchymal stem cells and hyaluronic acid derivative |
| CA2251983C (en) * | 1996-04-19 | 2003-12-16 | Sudhakar Kadiyala | Regeneration and augmentation of bone using mesenchymal stem cells |
| US5827740A (en) * | 1996-07-30 | 1998-10-27 | Osiris Therapeutics, Inc. | Adipogenic differentiation of human mesenchymal stem cells |
| CA2271758A1 (en) * | 1996-11-15 | 1998-05-22 | Osiris Therapeutics, Inc. | Msc-megakaryocyte precursor composition and method of isolating mscs associated with isolated megakaryocytes by isolating megakaryocytes |
| ES2285779T3 (es) * | 1997-07-03 | 2007-11-16 | Osiris Therapeutics, Inc. | Celulas madre mesenquimatosas humanas de sangre periferica. |
| ATE307195T1 (de) * | 1997-07-14 | 2005-11-15 | Osiris Therapeutics Inc | Herzmuskelregenerierung unter verwendung mesenchymaler stammzellen |
| AU9127098A (en) * | 1997-09-04 | 1999-03-22 | Osiris Therapeutics, Inc. | Ligands that modulate differentiation of mesenchymal stem cells |
| AU9231998A (en) * | 1997-09-20 | 1999-04-12 | Osiris Therapeutics, Inc. | Antigen presenting mesenchymal stem cells |
| AU9513898A (en) * | 1997-10-03 | 1999-04-27 | Osiris Therapeutics, Inc. | Human hox c10 and polynucleotides encoding |
| US6429012B1 (en) * | 1997-10-06 | 2002-08-06 | Viacell, Inc. | Cell population containing non-fetal hemangioblasts and method for producing same |
| AU1203999A (en) * | 1997-10-31 | 1999-05-24 | Osiris Therapeutics, Inc. | Human slit polypeptide and polynucleotides encoding same |
| PT1062321E (pt) * | 1998-03-13 | 2005-05-31 | Osiris Therapeutics Inc | Utilizacoes para celulas estaminais mesenquimais humanas nao autologas |
| US6368636B1 (en) * | 1998-03-18 | 2002-04-09 | Osiris Therapeutics, Inc. | Mesenchymal stem cells for prevention and treatment of immune responses in transplantation |
| EP1066052B1 (de) * | 1998-03-18 | 2006-02-01 | Osiris Therapeutics, Inc. | Mesenchymale stammzellen für die prävention und behandlung von immunantworten bei transplantationen |
| CA2328425A1 (en) * | 1998-05-22 | 1999-12-02 | Osiris Therapeutics, Inc. | Production of megakaryocytes by co-culturing human mesenchymal stem cells with cd34+ cells |
| ES2292245T3 (es) * | 1998-05-29 | 2008-03-01 | Osiris Therapeutics, Inc. | Celulas madre mesenquimaticas cd45+ y/o fibroblasto+humanas. |
| DK1084230T3 (da) * | 1998-06-08 | 2008-03-03 | Osiris Therapeutics Inc | Regulering af hæmatopoietisk stamcelledifferentiering ved anvendelse af humane mesenkymstamceller |
| JP4526186B2 (ja) * | 1998-06-08 | 2010-08-18 | オシリス セラピューティクス,インコーポレイテッド | 造血幹細胞を試験管内で維持する方法と組成物 |
| US6372494B1 (en) * | 1999-05-14 | 2002-04-16 | Advanced Tissue Sciences, Inc. | Methods of making conditioned cell culture medium compositions |
| US6239157B1 (en) * | 1999-09-10 | 2001-05-29 | Osiris Therapeutics, Inc. | Inhibition of osteoclastogenesis |
| US6685936B2 (en) * | 1999-10-12 | 2004-02-03 | Osiris Therapeutics, Inc. | Suppressor cells induced by culture with mesenchymal stem cells for treatment of immune responses in transplantation |
| US20020151496A1 (en) * | 2000-12-08 | 2002-10-17 | Bringmann Peter W. | Novel fibroblast growth factors |
| JP4358621B2 (ja) * | 2001-08-08 | 2009-11-04 | 泰彦 田畑 | 細胞と細胞増殖因子とからなる腎臓の再生のための材料 |
| AU2003225791A1 (en) * | 2002-03-15 | 2003-09-29 | Department Of Veterans Affairs, Rehabilitation R And D Service | Methods and compositions for directing cells to target organs |
| EP1562636A4 (de) | 2002-11-05 | 2007-01-31 | Brigham & Womens Hospital | Mesenchymale stammzellen und anwendungsverfahren dafür |
| US20040258670A1 (en) * | 2002-12-05 | 2004-12-23 | Case Western Reserve University | Cell-based therapies for ischemia |
| ATE482725T1 (de) | 2003-04-01 | 2010-10-15 | Us Dept Of Veteran S Affaires | Auf stammzellen, vorläuferzellen oder targetzellen basierende behandlung von multiorganversagen. |
-
2004
- 2004-03-31 AT AT04758676T patent/ATE482725T1/de not_active IP Right Cessation
- 2004-03-31 AU AU2004227342A patent/AU2004227342B2/en not_active Ceased
- 2004-03-31 CA CA2809195A patent/CA2809195C/en not_active Expired - Fee Related
- 2004-03-31 WO PCT/US2004/009922 patent/WO2004090112A2/en not_active Ceased
- 2004-03-31 EP EP10173543A patent/EP2263698A1/de not_active Withdrawn
- 2004-03-31 CA CA2784829A patent/CA2784829C/en not_active Expired - Fee Related
- 2004-03-31 DE DE602004029337T patent/DE602004029337D1/de not_active Expired - Lifetime
- 2004-03-31 US US10/551,317 patent/US8603462B2/en not_active Expired - Fee Related
- 2004-03-31 EP EP10181206A patent/EP2335738A1/de not_active Withdrawn
- 2004-03-31 EP EP04758676A patent/EP1608411B1/de not_active Expired - Lifetime
- 2004-03-31 CA CA2521217A patent/CA2521217C/en not_active Expired - Fee Related
-
2011
- 2011-01-04 AU AU2011200017A patent/AU2011200017B2/en not_active Ceased
-
2013
- 2013-09-18 US US14/030,859 patent/US20140086886A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2335738A1 (de) | 2011-06-22 |
| EP1608411A2 (de) | 2005-12-28 |
| CA2521217A1 (en) | 2004-10-21 |
| US8603462B2 (en) | 2013-12-10 |
| EP1608411B1 (de) | 2010-09-29 |
| WO2004090112A3 (en) | 2005-03-10 |
| CA2784829C (en) | 2015-10-06 |
| AU2011200017A1 (en) | 2011-01-27 |
| CA2784829A1 (en) | 2004-10-21 |
| EP1608411A4 (de) | 2007-08-29 |
| CA2809195A1 (en) | 2004-10-21 |
| US20140086886A1 (en) | 2014-03-27 |
| US20070178071A1 (en) | 2007-08-02 |
| EP2263698A1 (de) | 2010-12-22 |
| WO2004090112A2 (en) | 2004-10-21 |
| AU2011200017B2 (en) | 2012-04-19 |
| CA2521217C (en) | 2013-05-14 |
| AU2004227342B2 (en) | 2011-01-20 |
| AU2004227342A1 (en) | 2004-10-21 |
| WO2004090112B1 (en) | 2005-04-21 |
| DE602004029337D1 (de) | 2010-11-11 |
| CA2809195C (en) | 2014-05-20 |
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