DK3219321T3 - Fedtvævsafledte stromale stamceller til anvendelse til behandling af refraktære komplekse perianale fistler ved crohns sygdom - Google Patents

Fedtvævsafledte stromale stamceller til anvendelse til behandling af refraktære komplekse perianale fistler ved crohns sygdom Download PDF

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Publication number
DK3219321T3
DK3219321T3 DK17160932.4T DK17160932T DK3219321T3 DK 3219321 T3 DK3219321 T3 DK 3219321T3 DK 17160932 T DK17160932 T DK 17160932T DK 3219321 T3 DK3219321 T3 DK 3219321T3
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fistles
derivated
crohn
disease
treatment
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DK17160932.4T
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Danish (da)
English (en)
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Eduardo Bravo
Maria Pascual
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Takeda Pharmaceuticals Co
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/35—Fat tissue; Adipocytes; Stromal cells; Connective tissues
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0653—Adipocytes; Adipose tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK17160932.4T 2016-03-14 2017-03-14 Fedtvævsafledte stromale stamceller til anvendelse til behandling af refraktære komplekse perianale fistler ved crohns sygdom DK3219321T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1604304.4A GB201604304D0 (en) 2016-03-14 2016-03-14 Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease

Publications (1)

Publication Number Publication Date
DK3219321T3 true DK3219321T3 (da) 2022-04-25

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DK17160932.4T DK3219321T3 (da) 2016-03-14 2017-03-14 Fedtvævsafledte stromale stamceller til anvendelse til behandling af refraktære komplekse perianale fistler ved crohns sygdom

Country Status (27)

Country Link
US (3) US10357518B2 (enExample)
EP (2) EP3219321B1 (enExample)
JP (2) JP6931656B2 (enExample)
KR (1) KR102277789B1 (enExample)
CN (2) CN115569151A (enExample)
AU (1) AU2017232718B2 (enExample)
BE (1) BE1024781B1 (enExample)
CA (1) CA3017694C (enExample)
CY (1) CY1125513T1 (enExample)
DE (1) DE102017002458B4 (enExample)
DK (1) DK3219321T3 (enExample)
ES (2) ES2681774B1 (enExample)
FR (1) FR3048614B1 (enExample)
GB (2) GB201604304D0 (enExample)
HR (1) HRP20220539T1 (enExample)
HU (1) HUE058739T2 (enExample)
IL (2) IL261730B2 (enExample)
LT (1) LT3219321T (enExample)
MX (1) MX2018010699A (enExample)
NL (1) NL2018512B1 (enExample)
NO (1) NO345415B1 (enExample)
PL (1) PL3219321T3 (enExample)
RS (1) RS63163B1 (enExample)
RU (1) RU2742308C2 (enExample)
SG (2) SG10202008992YA (enExample)
SI (1) SI3219321T1 (enExample)
WO (1) WO2017158509A1 (enExample)

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WO2018183941A2 (en) 2017-03-30 2018-10-04 Progenity Inc. Treatment of a disease of the gastrointestinal tract with live biotherapeutics
JP7628499B2 (ja) * 2019-02-27 2025-02-10 武田薬品工業株式会社 同種異系療法のための改良された幹細胞集団
CN115297875A (zh) * 2020-03-11 2022-11-04 迈索布拉斯特国际有限公司 治疗炎症性肠病的方法ii
BR112022017560A2 (pt) * 2020-03-11 2022-12-27 Mesoblast Int Sarl Método para tratar doença inflamatória intestinal i
CN111481573A (zh) * 2020-03-26 2020-08-04 卡替（上海）生物技术股份有限公司 牙髓间充质干细胞在制备克罗恩病治疗药物中的用途
CN116801892A (zh) * 2020-11-25 2023-09-22 旗舰创业股份有限公司 脂肪生成细胞组合物和方法
CA3200227A1 (en) * 2020-11-25 2022-06-02 Alexandra Sophie DE BOER Adipogenic cell compositions and methods
EP4531879A1 (en) * 2022-05-25 2025-04-09 Flagship Pioneering Innovations VI, LLC Compositions of secretory and/or catalytic cells and methods using the same

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IL261730B2 (en) 2024-05-01
SI3219321T1 (sl) 2022-05-31
NL2018512B1 (en) 2017-09-07
BE1024781B1 (de) 2018-07-02
NL2018512A (en) 2017-03-30
GB2548490B (en) 2020-09-02
KR102277789B1 (ko) 2021-07-15
NO20170376A1 (en) 2017-09-15
KR20180120261A (ko) 2018-11-05
FR3048614A1 (enExample) 2017-09-15
JP2021119789A (ja) 2021-08-19
ES2681774A1 (es) 2018-09-14
IL298107A (en) 2023-01-01
ES2681774B1 (es) 2019-12-26
US20220249574A1 (en) 2022-08-11
HUE058739T2 (hu) 2022-09-28
BE1024781A1 (de) 2018-06-27
CA3017694A1 (en) 2017-09-21
MX2018010699A (es) 2019-01-14
AU2017232718B2 (en) 2024-01-18
GB201604304D0 (en) 2016-04-27
US20170258851A1 (en) 2017-09-14
US11273182B2 (en) 2022-03-15
US12213998B2 (en) 2025-02-04
US10357518B2 (en) 2019-07-23
IL298107B2 (en) 2024-02-01
CN115569151A (zh) 2023-01-06
RU2742308C2 (ru) 2021-02-04
CN108883135A (zh) 2018-11-23
LT3219321T (lt) 2022-05-10
CN108883135B (zh) 2022-11-04
EP4074322A1 (en) 2022-10-19
DE102017002458B4 (de) 2019-04-25
GB2548490A (en) 2017-09-20
GB201704065D0 (en) 2017-04-26
RU2018131519A (ru) 2020-04-15
BR112018068493A8 (pt) 2022-06-28
US20190381106A1 (en) 2019-12-19
IL298107B1 (en) 2023-10-01
SG10202008992YA (en) 2020-10-29
JP6931656B2 (ja) 2021-09-08
SG11201807404XA (en) 2018-09-27
WO2017158509A1 (en) 2017-09-21
IL261730B1 (en) 2024-01-01
IL261730A (en) 2018-10-31
JP2019508455A (ja) 2019-03-28
DE102017002458A1 (de) 2017-09-14
AU2017232718A1 (en) 2018-10-04
RS63163B1 (sr) 2022-05-31
CY1125513T1 (el) 2024-12-13
BR112018068493A2 (pt) 2019-01-22
ES2911718T3 (es) 2022-05-20
RU2018131519A3 (enExample) 2020-07-10
EP3219321A1 (en) 2017-09-20
CA3017694C (en) 2024-02-27
EP3219321B1 (en) 2022-03-30
NO345415B1 (en) 2021-01-18
FR3048614B1 (fr) 2020-02-21
HRP20220539T1 (hr) 2022-06-10
PL3219321T3 (pl) 2022-05-30

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