BR0008552A - Células tronco e redes derivadas de tecido adiposo - Google Patents
Células tronco e redes derivadas de tecido adiposoInfo
- Publication number
- BR0008552A BR0008552A BR0008552-9A BR0008552A BR0008552A BR 0008552 A BR0008552 A BR 0008552A BR 0008552 A BR0008552 A BR 0008552A BR 0008552 A BR0008552 A BR 0008552A
- Authority
- BR
- Brazil
- Prior art keywords
- cells
- derived
- adipose tissue
- stem cells
- provides
- Prior art date
Links
- 210000000130 stem cell Anatomy 0.000 title abstract 5
- 210000000577 adipose tissue Anatomy 0.000 title abstract 4
- 210000004027 cell Anatomy 0.000 abstract 4
- 238000000338 in vitro Methods 0.000 abstract 2
- 238000001727 in vivo Methods 0.000 abstract 2
- 210000001519 tissue Anatomy 0.000 abstract 2
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 abstract 1
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 abstract 1
- 210000001789 adipocyte Anatomy 0.000 abstract 1
- 230000024245 cell differentiation Effects 0.000 abstract 1
- 230000010261 cell growth Effects 0.000 abstract 1
- 239000003636 conditioned culture medium Substances 0.000 abstract 1
- 210000002808 connective tissue Anatomy 0.000 abstract 1
- 210000003743 erythrocyte Anatomy 0.000 abstract 1
- 210000002744 extracellular matrix Anatomy 0.000 abstract 1
- 230000012010 growth Effects 0.000 abstract 1
- 229940088597 hormone Drugs 0.000 abstract 1
- 239000005556 hormone Substances 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0658—Skeletal muscle cells, e.g. myocytes, myotubes, myoblasts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0068—General culture methods using substrates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0653—Adipocytes; Adipose tissue
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0654—Osteocytes, Osteoblasts, Odontocytes; Bones, Teeth
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0655—Chondrocytes; Cartilage
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
- C12N2500/24—Iron; Fe chelators; Transferrin
- C12N2500/25—Insulin-transferrin; Insulin-transferrin-selenium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/38—Vitamins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/42—Organic phosphate, e.g. beta glycerophosphate
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/01—Modulators of cAMP or cGMP, e.g. non-hydrolysable analogs, phosphodiesterase inhibitors, cholera toxin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/33—Insulin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/38—Hormones with nuclear receptors
- C12N2501/39—Steroid hormones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
- C12N2502/1305—Adipocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
- C12N2506/1346—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells
- C12N2506/1384—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells from adipose-derived stem cells [ADSC], from adipose stromal stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Rheumatology (AREA)
- Developmental Biology & Embryology (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Materials For Medical Uses (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Prostheses (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Abstract
"CéLULAS TRONCO E REDES DERIVADAS DE TECIDO ADIPOSO". A presente invenção fornece células tronco e redes derivadas de tecido adiposo. Em um aspecto, a presente invenção fornece uma célula tronco lipo-derivada substancialmente livre de adipócitos e células vermelhas sang³íneas e populações clonais de células tronco de tecido conectivo. As células podem ser empregadas, isoladas ou em composições biologicamente compatíveis, para gerar tecidos e estruturas diferenciadas, tanto in vivo como in vitro. Adicionalmente, as células podem ser expandidas e cultivadas para produzir hormónios e para fornecer meios de cultura condicionados para suportar o crescimento e expansão de outras populações de células. Em um outro aspecto, a presente invenção fornece uma rede lipo-derivada substancialmente desprovida de células, que inclui material de matriz extracelular de tecido adiposo. A rede pode ser usada como um substrato para facilitar o crescimento e diferenciação de células, seja in vivo ou in vitro, em tecidos ou estruturas primordiais ou mesmo maduros.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12371199P | 1999-03-10 | 1999-03-10 | |
US16246299P | 1999-10-29 | 1999-10-29 | |
PCT/US2000/006232 WO2000053795A1 (en) | 1999-03-10 | 2000-03-10 | Adipose-derived stem cells and lattices |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0008552A true BR0008552A (pt) | 2002-05-07 |
Family
ID=26821819
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0008552-9A BR0008552A (pt) | 1999-03-10 | 2000-03-10 | Células tronco e redes derivadas de tecido adiposo |
Country Status (11)
Country | Link |
---|---|
US (2) | US20020076400A1 (pt) |
EP (1) | EP1165830B1 (pt) |
JP (3) | JP2002537849A (pt) |
KR (4) | KR100968165B1 (pt) |
CN (1) | CN1352696A (pt) |
AU (1) | AU784580B2 (pt) |
BR (1) | BR0008552A (pt) |
CA (1) | CA2366078C (pt) |
IL (1) | IL145002A0 (pt) |
RU (2) | RU2306335C2 (pt) |
WO (1) | WO2000053795A1 (pt) |
Families Citing this family (174)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6670398B2 (en) | 1997-05-14 | 2003-12-30 | Atherogenics, Inc. | Compounds and methods for treating transplant rejection |
ID23877A (id) | 1997-05-14 | 2000-05-25 | Atherogenics Inc | Senyawa-senyawa dan metode-metode untuk penghambatan ekspresi vcam-1 |
DE69841850D1 (de) | 1997-12-02 | 2010-09-30 | Artecel Sciences Inc | Differenzierung in osteoblasten der fettgewebe-stromalen zellen und ihre verwendungen |
US7001746B1 (en) | 1999-01-29 | 2006-02-21 | Artecel Sciences, Inc. | Methods and compositions for the differentiation of human preadipocytes into adipocytes |
US6777231B1 (en) * | 1999-03-10 | 2004-08-17 | The Regents Of The University Of California | Adipose-derived stem cells and lattices |
US20030082152A1 (en) | 1999-03-10 | 2003-05-01 | Hedrick Marc H. | Adipose-derived stem cells and lattices |
US20050153442A1 (en) * | 1999-03-10 | 2005-07-14 | Adam Katz | Adipose-derived stem cells and lattices |
AU2003901668A0 (en) * | 2003-03-28 | 2003-05-01 | Medvet Science Pty. Ltd. | Non-haemopoietic precursor cells |
US6429013B1 (en) | 1999-08-19 | 2002-08-06 | Artecel Science, Inc. | Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair |
US7078232B2 (en) | 1999-08-19 | 2006-07-18 | Artecel, Inc. | Adipose tissue-derived adult stem or stromal cells for the repair of articular cartilage fractures and uses thereof |
US6555374B1 (en) | 1999-08-19 | 2003-04-29 | Artecel Sciences, Inc. | Multiple mesodermal lineage differentiation potentials for adipose tissue-derived stromal cells and uses thereof |
US7582292B2 (en) | 2000-02-26 | 2009-09-01 | Artecel, Inc. | Adipose tissue derived stromal cells for the treatment of neurological disorders |
AU2001238695B2 (en) | 2000-02-26 | 2005-11-24 | Artecel Sciences, Inc. | Pleuripotent stem cells generated from adipose tissue-derived stromal cells and uses thereof |
EP1918366A1 (en) | 2000-02-26 | 2008-05-07 | Artecel, Inc. | Pleuripotent stem cells generated from adipose tissue-derived stromal cells and uses thereof |
FR2819265B1 (fr) * | 2001-01-10 | 2004-01-02 | Centre Nat Rech Scient | Cellules du tissu adipeux extramedullaire et leurs applications dans la reconstitution des lignees hematopoietiques |
US7202080B2 (en) | 2001-03-29 | 2007-04-10 | Ixion Biotechnology, Inc. | Method for transdifferentiation of non-pancreatic stem cells to the pancreatic differentiation pathway |
WO2003008592A1 (fr) * | 2001-07-19 | 2003-01-30 | Yasuhiko Tabata | Cellules embryonnaires polyfonctionnelles provenant de tissus adipeux |
US20030054331A1 (en) * | 2001-09-14 | 2003-03-20 | Stemsource, Inc. | Preservation of non embryonic cells from non hematopoietic tissues |
PL374557A1 (en) * | 2001-11-09 | 2005-10-31 | Artecel Sciences, Inc. | Endocrine pancreas differentiation of adipose tissue-derived stromal cells and uses thereof |
EP1892289A3 (en) * | 2001-11-09 | 2008-03-05 | Artecel Sciences, Inc. | Adipose tissue-derived stromal cells for the repair of corneal and intra-orbital defects and uses thereof |
US7771716B2 (en) | 2001-12-07 | 2010-08-10 | Cytori Therapeutics, Inc. | Methods of using regenerative cells in the treatment of musculoskeletal disorders |
US9597395B2 (en) | 2001-12-07 | 2017-03-21 | Cytori Therapeutics, Inc. | Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions |
US20050048035A1 (en) | 2001-12-07 | 2005-03-03 | Fraser John K. | Methods of using regenerative cells in the treatment of stroke and related diseases and disorders |
US7585670B2 (en) | 2001-12-07 | 2009-09-08 | Cytori Therapeutics, Inc. | Automated methods for isolating and using clinically safe adipose derived regenerative cells |
AU2002357135C1 (en) * | 2001-12-07 | 2009-01-22 | Macropore Biosurgery, Inc. | Systems and methods for treating patients with processed lipoaspirate cells |
US20050095228A1 (en) | 2001-12-07 | 2005-05-05 | Fraser John K. | Methods of using regenerative cells in the treatment of peripheral vascular disease and related disorders |
KR20040094910A (ko) * | 2002-04-03 | 2004-11-10 | 아르테셀 사이언스, 인크. | 개선된 지방세포 분화된 지방 유래 성체 줄기세포 및 이의용도 |
US20030205538A1 (en) | 2002-05-03 | 2003-11-06 | Randel Dorian | Methods and apparatus for isolating platelets from blood |
US7992725B2 (en) * | 2002-05-03 | 2011-08-09 | Biomet Biologics, Llc | Buoy suspension fractionation system |
US7832566B2 (en) | 2002-05-24 | 2010-11-16 | Biomet Biologics, Llc | Method and apparatus for separating and concentrating a component from a multi-component material including macroparticles |
US20060278588A1 (en) | 2002-05-24 | 2006-12-14 | Woodell-May Jennifer E | Apparatus and method for separating and concentrating fluids containing multiple components |
US7845499B2 (en) | 2002-05-24 | 2010-12-07 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
DE10392686T5 (de) | 2002-05-24 | 2005-07-07 | Biomet Mfg. Corp., Warsaw | Vorrichtung und Verfahren zum Trennen und Konzentrieren von Flüssigkeiten, welche mehrere Komponenten enthalten |
AU2003240281A1 (en) | 2002-06-14 | 2003-12-31 | Case Western Reserve University | Cell targeting methods and compositions |
JP4603883B2 (ja) * | 2002-07-31 | 2010-12-22 | サントル・ナショナル・ドゥ・ラ・レシェルシュ・サイエンティフィーク−セ・エン・エール・エス− | 脂肪組織由来の幹細胞および前記細胞から分化した細胞 |
FR2843123B1 (fr) * | 2002-07-31 | 2007-11-02 | Saint Laurent Parfums | Cellules souches issues de tissu adipeux humain |
US20040235121A1 (en) * | 2002-08-29 | 2004-11-25 | Integrigen, Inc. | High copy number plasmids and their derivatives |
KR100539371B1 (ko) * | 2002-10-21 | 2005-12-27 | 메디칸(주) | 인체 세포의 체외배양 방법 |
US7233684B2 (en) * | 2002-11-25 | 2007-06-19 | Eastman Kodak Company | Imaging method and system using affective information |
RU2372924C2 (ru) * | 2003-02-20 | 2009-11-20 | Ситори Терапьютикс,Инк | Применение композиции, состоящей из концентрированной клеточной популяции, представляющей собой стволовые клетки и недифференцированные клетки-предшественники |
US20040193274A1 (en) * | 2003-03-28 | 2004-09-30 | Trieu Hai H. | Materials and methods for augmenting and/or repairing intervertebral discs |
US20080044899A1 (en) * | 2003-06-13 | 2008-02-21 | Koichiro Kano | Differentiated Cells Originating in Precursor Fat Cells and Method of Acquiring the Same |
EP2336298B1 (en) | 2003-06-27 | 2016-02-17 | DePuy Synthes Products, Inc. | Postpartum cells derived from placental tissue and methods of making and using the same |
US20060223177A1 (en) | 2003-06-27 | 2006-10-05 | Ethicon Inc. | Postpartum cells derived from umbilical cord tissue, and methods of making and using the same |
US9592258B2 (en) | 2003-06-27 | 2017-03-14 | DePuy Synthes Products, Inc. | Treatment of neurological injury by administration of human umbilical cord tissue-derived cells |
FR2859381B1 (fr) * | 2003-09-05 | 2008-07-25 | Centre Nat Rech Scient | Utilisaton de cellules issues du tissu adipeux pour induire la formation d'un reseau vasculaire fonctionnel |
AU2004280149A1 (en) * | 2003-09-17 | 2005-04-21 | Macropore Biosurgery Inc. | Methods of using regenerative cells in the treatment of peripheral vascular disease and related disorders |
JP2007508018A (ja) | 2003-10-08 | 2007-04-05 | べト−ステム インコーポレイテッド | 新規の幹細胞組成物の調製法および使用法、ならびにこの組成物を含有するキット |
DE602004030823D1 (de) * | 2003-11-04 | 2011-02-10 | Biomaster Inc | Verfahren und system zur herstellung von stammzellen aus fettgewebe |
AU2003286084A1 (en) * | 2003-12-23 | 2005-07-14 | Carag Ag | Method for isolating cells from mammary secretion |
JP5019883B2 (ja) | 2004-01-16 | 2012-09-05 | カーネギー メロン ユニバーシティ | 核磁気共鳴技術のための細胞標識 |
EP2298862B1 (en) | 2004-03-22 | 2017-08-30 | Mesoblast International Sàrl | Mesenchymal stem cells and uses therefor |
ES2313805B1 (es) | 2004-10-04 | 2009-12-23 | Cellerix, S.L. | Identificacion y aislamiento de celulas multipotentes de tejido mesenquimal no osteocondral. |
US20060045872A1 (en) | 2004-08-25 | 2006-03-02 | Universidad Autonoma De Madrid Ciudad Universitaria de Cantoblanco | Use of adipose tissue-derived stromal stem cells in treating fistula |
EP1805300A4 (en) * | 2004-09-14 | 2009-09-09 | Univ Columbia | DIFFERENTIATION OF MESENCHYMAL STEM CELLS TO THE HEART REPAIR PROMOTING CARDIOVASCULAR CELLS |
US8431397B2 (en) * | 2004-09-14 | 2013-04-30 | The Trustees Of Columbia University In The City Of New York | Differentiation of human mesenchymal stem cells to cardiac progenitor cells that promote cardiac repair |
US20060134781A1 (en) * | 2004-12-07 | 2006-06-22 | Bacterin International, Inc. | Three-dimensional cell culture system |
US20230332095A1 (en) * | 2004-12-23 | 2023-10-19 | Tissue Genesis International Llc | Cell separation apparatus and methods of use |
EP1830862B1 (en) | 2004-12-30 | 2012-12-19 | PrimeGen Biotech LLC | Adipose-derived stem cells for tissue regeneration and wound healing |
EP1848472B1 (en) | 2005-02-07 | 2015-04-01 | Hanuman LLC | Platelet rich plasma concentrate apparatus and method |
US7708152B2 (en) | 2005-02-07 | 2010-05-04 | Hanuman Llc | Method and apparatus for preparing platelet rich plasma and concentrates thereof |
US7866485B2 (en) | 2005-02-07 | 2011-01-11 | Hanuman, Llc | Apparatus and method for preparing platelet rich plasma and concentrates thereof |
WO2006128029A2 (en) * | 2005-05-25 | 2006-11-30 | University Of Virginia Patent Foundation | Production of osteoclasts from adipose tissues |
US8796020B2 (en) * | 2005-06-17 | 2014-08-05 | Inha-Industry Partnership Institute | Manufacturing process for fresh and frozen stem cells |
JP4907908B2 (ja) * | 2005-06-29 | 2012-04-04 | ルネサスエレクトロニクス株式会社 | 駆動回路及び表示装置 |
TW200726474A (en) * | 2005-07-15 | 2007-07-16 | Cognate Therapeutics Inc | The immunophenotype and immunogenicity of human adipose derived cells |
US7531355B2 (en) | 2005-07-29 | 2009-05-12 | The Regents Of The University Of California | Methods and compositions for smooth muscle reconstruction |
WO2007019107A2 (en) * | 2005-07-29 | 2007-02-15 | University Of Virginia Patent Foundation | Adipose tissue stem cells, perivascular cells and pericytes |
CN1912109B (zh) * | 2005-08-09 | 2010-09-15 | 中国人民解放军军事医学科学院野战输血研究所 | 一种组织工程化脂肪组织的构建方法与应用 |
JP2009506769A (ja) * | 2005-09-02 | 2009-02-19 | エージェンシー フォー サイエンス,テクノロジー アンド リサーチ | 間充織幹細胞誘導方法 |
US9029146B2 (en) | 2005-09-02 | 2015-05-12 | Agency For Science, Technology And Research | Mesenchymal stem cell conditioned medium |
WO2007030469A2 (en) * | 2005-09-06 | 2007-03-15 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Transplantable cell growth niche and related compositions and methods |
SI1926813T2 (sl) | 2005-09-23 | 2019-11-29 | Tigenix S A U | Celična populacija z imunoregulatorno aktivnostjo, postopek za izolacijo in uporabe |
KR100679642B1 (ko) * | 2005-11-16 | 2007-02-06 | 주식회사 알앤엘바이오 | 인간 지방조직 유래 다분화능 줄기세포 및 이를 함유하는세포치료제 |
WO2007070870A1 (en) | 2005-12-16 | 2007-06-21 | Ethicon, Inc. | Compositions and methods for inhibiting adverse immune response in histocompatibility-mismatched transplantation |
US9125906B2 (en) | 2005-12-28 | 2015-09-08 | DePuy Synthes Products, Inc. | Treatment of peripheral vascular disease using umbilical cord tissue-derived cells |
JP2009525044A (ja) | 2006-01-30 | 2009-07-09 | ユニバーシティ オブ バージニア パテント ファウンデーション | 間葉系幹細胞集合体を調製および特性評価する方法ならびにそれらの使用 |
US20090175835A1 (en) * | 2006-02-07 | 2009-07-09 | Korea Institute Of Radiological & Medical Sciences | Composition for treating damage of central or peripheral nerve system |
US8163018B2 (en) * | 2006-02-14 | 2012-04-24 | Warsaw Orthopedic, Inc. | Treatment of the vertebral column |
US20070227547A1 (en) * | 2006-02-14 | 2007-10-04 | Sdgi Holdings, Inc. | Treatment of the vertebral column |
US20070213718A1 (en) * | 2006-02-14 | 2007-09-13 | Sdgi Holdings, Inc. | Treatment of the vertebral column |
US20070213717A1 (en) * | 2006-02-14 | 2007-09-13 | Sdgi Holdings, Inc. | Biological fusion in the vertebral column |
CA2646384C (en) * | 2006-03-23 | 2020-03-24 | Pluristem Ltd. | Methods for cell expansion and uses of cells and conditioned media produced thereby for therapy |
US20110171182A1 (en) * | 2006-03-23 | 2011-07-14 | Pluristem Ltd. | Methods for cell expansion and uses of cells and conditioned media produced thereby for therapy |
CN101558151B (zh) * | 2006-03-23 | 2015-10-21 | 普拉里斯坦有限公司 | 细胞扩增方法和藉此产生的细胞和条件培养基用于治疗的用途 |
EP2010646A2 (en) | 2006-04-14 | 2009-01-07 | Carnegie Mellon University | Cellular labeling and quantification for nuclear magnetic resonance techniques |
FR2901136B1 (fr) * | 2006-05-18 | 2010-10-01 | Centre Nat Rech Scient | Utilisation de cellules derivees du tissu adipeux pour la preparation d'un medicament anti-tumoral |
US8567609B2 (en) | 2006-05-25 | 2013-10-29 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
US20100023129A1 (en) * | 2008-07-22 | 2010-01-28 | Guo-Feng Xu | Jawbone prosthesis and method of manufacture |
EP2075329A4 (en) | 2006-09-25 | 2010-10-20 | Univ Osaka | COMPOSITION FOR REGENERATING PERIODONTAL DURUM TISSUE AND METHOD FOR REGENERATING PERIODONTAL DURUM TISSUE |
WO2008060374A2 (en) | 2006-10-06 | 2008-05-22 | University Of Virginia Patent Foundation | Methods and compositions useful for diabetic wound healing |
US8034014B2 (en) | 2007-03-06 | 2011-10-11 | Biomet Biologics, Llc | Angiogenesis initation and growth |
US7806276B2 (en) | 2007-04-12 | 2010-10-05 | Hanuman, Llc | Buoy suspension fractionation system |
US8328024B2 (en) | 2007-04-12 | 2012-12-11 | Hanuman, Llc | Buoy suspension fractionation system |
JP2008278822A (ja) * | 2007-05-11 | 2008-11-20 | Olympus Corp | 生体組織分解方法 |
JP2008278842A (ja) * | 2007-05-14 | 2008-11-20 | Nippon Inst For Biological Science | 脂肪組織間質細胞の神経細胞への分化誘導方法並びに分化誘導された該神経細胞 |
JP5388297B2 (ja) * | 2007-06-08 | 2014-01-15 | 株式会社バイオマスター | アディポクラスター |
JPWO2008153179A1 (ja) * | 2007-06-14 | 2010-08-26 | 財団法人先端医療振興財団 | 脂肪組織由来多系統前駆細胞 |
EP2170975B1 (en) | 2007-07-10 | 2018-05-02 | Carnegie Mellon University | Compositions and methods for producing cellular labels for nuclear magnetic resonance techniques |
PT2200622E (pt) | 2007-09-19 | 2012-11-06 | Pluristem Ltd | Células aderentes provenientes de tecido adiposo ou placentário e respetiva utilização terapêutica |
US20090192528A1 (en) * | 2008-01-29 | 2009-07-30 | Biomet Biologics, Inc. | Method and device for hernia repair |
EP2252686B1 (en) * | 2008-02-11 | 2017-10-11 | The Johns Hopkins University | Compositions and methods for implantation of adipose tissue and adipose tissue products |
PL2259774T3 (pl) | 2008-02-27 | 2013-04-30 | Biomet Biologics Llc | Sposoby i kompozycje dla wprowadzania antagonisty receptora interleukiny-1 |
EP2254991B1 (en) | 2008-02-29 | 2018-08-22 | Biomet Manufacturing, LLC | A system and process for separating a material |
SG188918A1 (pt) | 2008-03-17 | 2013-04-30 | Agency Science Tech & Res | |
US8012077B2 (en) | 2008-05-23 | 2011-09-06 | Biomet Biologics, Llc | Blood separating device |
WO2010021993A1 (en) | 2008-08-19 | 2010-02-25 | Cytori Therapeutics, Inc. | Methods of using adipose tissue-derived cells in the treatment of the lymphatic system and malignant disease |
AU2009201915C1 (en) | 2008-08-22 | 2015-02-26 | Regeneus Ltd | Therapeutic methods |
US8524496B2 (en) | 2008-09-02 | 2013-09-03 | Pluristem Ltd. | Adherent cells from placenta tissue and use thereof in therapy |
JP5518893B2 (ja) | 2008-12-19 | 2014-06-11 | アドバンスト・テクノロジーズ・アンド・リジェネレイティブ・メディスン・エルエルシー | 肺ならびに肺の疾患および障害の治療 |
US10179900B2 (en) | 2008-12-19 | 2019-01-15 | DePuy Synthes Products, Inc. | Conditioned media and methods of making a conditioned media |
US8187475B2 (en) | 2009-03-06 | 2012-05-29 | Biomet Biologics, Llc | Method and apparatus for producing autologous thrombin |
PL2411504T3 (pl) | 2009-03-26 | 2017-10-31 | Depuy Synthes Products Inc | Komórki ludzkiej tkanki pępowinowej jako terapia choroby Alzheimera |
US8313954B2 (en) | 2009-04-03 | 2012-11-20 | Biomet Biologics, Llc | All-in-one means of separating blood components |
KR101738324B1 (ko) | 2009-05-01 | 2017-05-19 | 비미니 테크놀로지스 엘엘씨 | 조직 및 세포 부유화 이식편의 최적화 시스템, 방법 및 조성물 |
US8740383B2 (en) | 2009-05-06 | 2014-06-03 | University Of Virginia Patent Foundation | Self-illuminated handheld lens for retinal examination and photography and related method thereof |
IT1394570B1 (it) * | 2009-07-02 | 2012-07-05 | Fidia Farmaceutici | Materiale biologico adatto per la terapia dell osteoartrosi del danno dei legamenti e per il trattamento delle patologie delle articolazioni. |
US9011800B2 (en) | 2009-07-16 | 2015-04-21 | Biomet Biologics, Llc | Method and apparatus for separating biological materials |
WO2011019822A2 (en) * | 2009-08-11 | 2011-02-17 | The Johns Hopkins University | Compositions and methods for implantation of processed adipose tissue and processed adipose tissue products |
US9034386B2 (en) * | 2009-12-17 | 2015-05-19 | Queen's University At Kingston | Decellularized adipose tissue |
EP2926821B1 (en) | 2010-03-05 | 2019-12-25 | Tissue Genesis, LLC | Compositions to support tissue integration and inosculation of transplanted tissue and transplanted engineered penile tissue with adipose stromal cells |
US8591391B2 (en) | 2010-04-12 | 2013-11-26 | Biomet Biologics, Llc | Method and apparatus for separating a material |
EP3502254B1 (en) | 2010-04-23 | 2024-11-06 | Cold Spring Harbor Laboratory | Novel structurally designed shrnas |
US8883210B1 (en) | 2010-05-14 | 2014-11-11 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
US10130736B1 (en) | 2010-05-14 | 2018-11-20 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
US9352003B1 (en) | 2010-05-14 | 2016-05-31 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
EP2590695A4 (en) | 2010-07-09 | 2017-09-06 | The Gid Group, Inc. | Apparatus and methods relating to collecting and processing human biological material containing adipose |
US9206387B2 (en) | 2010-07-09 | 2015-12-08 | The Gid Group, Inc. | Method and apparatus for processing adipose tissue |
US9296984B2 (en) | 2010-07-09 | 2016-03-29 | The Gid Group, Inc. | Tissue processing apparatus and method for processing adipose tissue |
WO2013106655A1 (en) | 2012-01-11 | 2013-07-18 | The Gid Group, Inc. | Method for processing adipose tissue and processing apparatus |
US9677042B2 (en) | 2010-10-08 | 2017-06-13 | Terumo Bct, Inc. | Customizable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system |
AU2011343513B2 (en) * | 2010-12-16 | 2016-07-14 | Ingeneron, Inc. | Methods and apparatus for enhanced recovery of cells and of cell-enriched matrix from tissue samples |
DK3156060T3 (da) * | 2011-03-15 | 2019-11-25 | Cell Ideas Pty Ltd | Farmaceutiske sammensætninger og topisk anvendelse deraf |
WO2012127320A1 (en) | 2011-03-22 | 2012-09-27 | Pluristem Ltd. | Methods for treating radiation or chemical injury |
US8834928B1 (en) | 2011-05-16 | 2014-09-16 | Musculoskeletal Transplant Foundation | Tissue-derived tissugenic implants, and methods of fabricating and using same |
WO2013192342A1 (en) * | 2012-06-20 | 2013-12-27 | Celula, Inc. | Materials and methods for processing cell populations |
US10206956B2 (en) | 2012-06-26 | 2019-02-19 | Rusty Property Holdings Pty Ltd. | Compositions and methods for reducing frequency and/or severity of headache |
US9642956B2 (en) | 2012-08-27 | 2017-05-09 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
CN102816796B (zh) * | 2012-09-04 | 2013-10-16 | 中国科学院广州生物医药与健康研究院 | c-Jun的N端缺失诱导多能性干细胞的方法和应用 |
EP3896145A1 (en) | 2012-09-06 | 2021-10-20 | GID BIO, Inc. | Tissue processing apparatus and method for processing adipose tissue |
US10143725B2 (en) | 2013-03-15 | 2018-12-04 | Biomet Biologics, Llc | Treatment of pain using protein solutions |
US9895418B2 (en) | 2013-03-15 | 2018-02-20 | Biomet Biologics, Llc | Treatment of peripheral vascular disease using protein solutions |
US9950035B2 (en) | 2013-03-15 | 2018-04-24 | Biomet Biologics, Llc | Methods and non-immunogenic compositions for treating inflammatory disorders |
US10208095B2 (en) | 2013-03-15 | 2019-02-19 | Biomet Manufacturing, Llc | Methods for making cytokine compositions from tissues using non-centrifugal methods |
US20140271589A1 (en) | 2013-03-15 | 2014-09-18 | Biomet Biologics, Llc | Treatment of collagen defects using protein solutions |
CN105531366A (zh) * | 2013-07-10 | 2016-04-27 | 新加坡科技研究局 | 用于分离基质血管组分的方法 |
CA2919374C (en) | 2013-07-30 | 2019-12-03 | Musculoskeletal Transplant Foundation | Acellular soft tissue-derived matrices and methods for preparing same |
US10336980B2 (en) | 2013-09-05 | 2019-07-02 | The Gid Group, Inc. | Tissue processing apparatus and method for processing adipose tissue |
WO2015073913A1 (en) | 2013-11-16 | 2015-05-21 | Terumo Bct, Inc. | Expanding cells in a bioreactor |
JP6783143B2 (ja) | 2014-03-25 | 2020-11-11 | テルモ ビーシーティー、インコーポレーテッド | 培地の受動的補充 |
CA2956681A1 (en) * | 2014-07-30 | 2016-02-04 | Claudia Eder | Transdifferentiated tissue graft |
WO2016049421A1 (en) | 2014-09-26 | 2016-03-31 | Terumo Bct, Inc. | Scheduled feed |
US9238090B1 (en) | 2014-12-24 | 2016-01-19 | Fettech, Llc | Tissue-based compositions |
US9713810B2 (en) | 2015-03-30 | 2017-07-25 | Biomet Biologics, Llc | Cell washing plunger using centrifugal force |
KR101719743B1 (ko) | 2015-04-06 | 2017-03-24 | 박준한 | 지방 조직으로부터 지방줄기세포를 수득하는 방법 |
US9757721B2 (en) | 2015-05-11 | 2017-09-12 | Biomet Biologics, Llc | Cell washing plunger using centrifugal force |
US10531957B2 (en) | 2015-05-21 | 2020-01-14 | Musculoskeletal Transplant Foundation | Modified demineralized cortical bone fibers |
US20160346432A1 (en) * | 2015-05-27 | 2016-12-01 | Cook Regentec Llc | Sheet-form cell growth scaffold particles and grafts, and methods for same |
WO2017004592A1 (en) | 2015-07-02 | 2017-01-05 | Terumo Bct, Inc. | Cell growth with mechanical stimuli |
US10912864B2 (en) | 2015-07-24 | 2021-02-09 | Musculoskeletal Transplant Foundation | Acellular soft tissue-derived matrices and methods for preparing same |
US11052175B2 (en) | 2015-08-19 | 2021-07-06 | Musculoskeletal Transplant Foundation | Cartilage-derived implants and methods of making and using same |
GB201604304D0 (en) | 2016-03-14 | 2016-04-27 | Tigenix S A U | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
US11965175B2 (en) | 2016-05-25 | 2024-04-23 | Terumo Bct, Inc. | Cell expansion |
US11104874B2 (en) | 2016-06-07 | 2021-08-31 | Terumo Bct, Inc. | Coating a bioreactor |
US11685883B2 (en) | 2016-06-07 | 2023-06-27 | Terumo Bct, Inc. | Methods and systems for coating a cell growth surface |
WO2018044791A1 (en) | 2016-08-30 | 2018-03-08 | Lifecell Corporation | Systems and methods for medical device control |
CN106318902A (zh) * | 2016-09-29 | 2017-01-11 | 广州赛莱拉干细胞科技股份有限公司 | 一种软骨细胞的培养方法 |
CN106434522A (zh) * | 2016-09-29 | 2017-02-22 | 广州赛莱拉干细胞科技股份有限公司 | 一种自体软骨细胞的三维培养方法 |
USD851777S1 (en) | 2017-01-30 | 2019-06-18 | Lifecell Corporation | Canister-type device for tissue processing |
US11624046B2 (en) | 2017-03-31 | 2023-04-11 | Terumo Bct, Inc. | Cell expansion |
JP7393945B2 (ja) | 2017-03-31 | 2023-12-07 | テルモ ビーシーティー、インコーポレーテッド | 細胞増殖 |
WO2019018002A1 (en) | 2017-07-18 | 2019-01-24 | The Gid Group, Inc. | ADIPOSE TISSUE DIGESTION SYSTEM AND METHOD FOR TREATING TISSUE |
KR102233530B1 (ko) | 2018-11-22 | 2021-03-31 | (주)프로스테믹스 | 엑소좀 및 이의 다양한 용도 |
US12043823B2 (en) | 2021-03-23 | 2024-07-23 | Terumo Bct, Inc. | Cell capture and expansion |
Family Cites Families (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US76400A (en) * | 1868-04-07 | Joseph collins and john knox | ||
US211602A (en) * | 1879-01-21 | Improvement in towing canal-boats | ||
US161817A (en) * | 1875-04-06 | Improvement in farm-gates | ||
US82152A (en) * | 1868-09-15 | Improvement in hay-knives | ||
US282275A (en) * | 1883-07-31 | Cooke | ||
US171146A (en) * | 1875-12-14 | Improvement in stove-pipe shelves | ||
US76396A (en) * | 1868-04-07 | John burke | ||
US13510A (en) * | 1855-08-28 | Nathan thompson | ||
US153441A (en) * | 1874-07-28 | Improvement in boiler-flue cleaners | ||
US153442A (en) * | 1874-07-28 | Improvement in rosettes | ||
US4438032A (en) * | 1981-01-30 | 1984-03-20 | The Regents Of The University Of California | Unique T-lymphocyte line and products derived therefrom |
DE3171608D1 (en) * | 1981-10-28 | 1985-09-05 | Ibm | Line circuit containing impedance adaptation means |
US5510254A (en) * | 1986-04-18 | 1996-04-23 | Advanced Tissue Sciences, Inc. | Three dimensional cell and tissue culture system |
US5336616A (en) * | 1990-09-12 | 1994-08-09 | Lifecell Corporation | Method for processing and preserving collagen-based tissues for transplantation |
US5811094A (en) * | 1990-11-16 | 1998-09-22 | Osiris Therapeutics, Inc. | Connective tissue regeneration using human mesenchymal stem cell preparations |
US5486359A (en) * | 1990-11-16 | 1996-01-23 | Osiris Therapeutics, Inc. | Human mesenchymal stem cells |
US5226914A (en) * | 1990-11-16 | 1993-07-13 | Caplan Arnold I | Method for treating connective tissue disorders |
WO1994000484A1 (en) | 1992-06-22 | 1994-01-06 | Young Henry E | Scar inhibitory factor and use thereof |
US5591625A (en) | 1993-11-24 | 1997-01-07 | Case Western Reserve University | Transduced mesenchymal stem cells |
FR2723315B1 (fr) * | 1994-08-02 | 1996-10-25 | Cird Galderma | Procede et composition pour stimuler la differenciation des cellules preadipocytaires et traitements therapeutiques associes |
US5688531A (en) * | 1994-12-23 | 1997-11-18 | Ramot University Authority For Applied Research And Industrial Development, Ltd. | Method for regulating bone forming cells |
US5736396A (en) * | 1995-01-24 | 1998-04-07 | Case Western Reserve University | Lineage-directed induction of human mesenchymal stem cell differentiation |
US5906934A (en) | 1995-03-14 | 1999-05-25 | Morphogen Pharmaceuticals, Inc. | Mesenchymal stem cells for cartilage repair |
US5765567A (en) * | 1995-03-22 | 1998-06-16 | Knowlton; Edward W. | Surgical method for breast reconstruction using a tissue flap |
EP0868505B1 (en) | 1995-11-16 | 2005-02-02 | Case Western Reserve University | In vitro chondrogenic induction of human mesenchymal stem cells |
WO1997026326A1 (en) * | 1996-01-16 | 1997-07-24 | Depuy Orthopaedics, Inc. | Isolation of precursor cells from hematopoietic and non-hematopoietic tissues and their use |
US6200606B1 (en) * | 1996-01-16 | 2001-03-13 | Depuy Orthopaedics, Inc. | Isolation of precursor cells from hematopoietic and nonhematopoietic tissues and their use in vivo bone and cartilage regeneration |
US5827740A (en) * | 1996-07-30 | 1998-10-27 | Osiris Therapeutics, Inc. | Adipogenic differentiation of human mesenchymal stem cells |
US5786207A (en) | 1997-05-28 | 1998-07-28 | University Of Pittsburgh | Tissue dissociating system and method |
US5817050A (en) * | 1997-05-29 | 1998-10-06 | Klein; Jeffrey A. | Liposuction cannula |
PT1028737E (pt) * | 1997-07-03 | 2007-07-11 | Osiris Therapeutics Inc | Células estaminais mesenquimatosas humanas de sangue periférico |
WO1999003980A1 (fr) * | 1997-07-16 | 1999-01-28 | Kirin Beer Kabushiki Kaisha | Cellules de stroma derivees d'agm |
FR2771102B1 (fr) * | 1997-11-14 | 2000-12-15 | Biocoral Inc | Procede pour induire la differenciation osteoblastique de cellules de tissu adipeux extramedullaire humain |
DE69841850D1 (de) | 1997-12-02 | 2010-09-30 | Artecel Sciences Inc | Differenzierung in osteoblasten der fettgewebe-stromalen zellen und ihre verwendungen |
CA2311729A1 (en) * | 1998-01-23 | 1999-07-29 | Imclone Systems Incorporated | Purified populations of stem cells |
US6777231B1 (en) * | 1999-03-10 | 2004-08-17 | The Regents Of The University Of California | Adipose-derived stem cells and lattices |
US20030082152A1 (en) * | 1999-03-10 | 2003-05-01 | Hedrick Marc H. | Adipose-derived stem cells and lattices |
US7266457B1 (en) * | 1999-05-21 | 2007-09-04 | Hesperos, Llc | High throughput functional genomics |
AUPQ147799A0 (en) * | 1999-07-07 | 1999-07-29 | Medvet Science Pty. Ltd. | Mesenchymal precursor cell |
US6555374B1 (en) * | 1999-08-19 | 2003-04-29 | Artecel Sciences, Inc. | Multiple mesodermal lineage differentiation potentials for adipose tissue-derived stromal cells and uses thereof |
US7078232B2 (en) * | 1999-08-19 | 2006-07-18 | Artecel, Inc. | Adipose tissue-derived adult stem or stromal cells for the repair of articular cartilage fractures and uses thereof |
US6429013B1 (en) * | 1999-08-19 | 2002-08-06 | Artecel Science, Inc. | Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair |
AU2001238695B2 (en) * | 2000-02-26 | 2005-11-24 | Artecel Sciences, Inc. | Pleuripotent stem cells generated from adipose tissue-derived stromal cells and uses thereof |
FR2819265B1 (fr) * | 2001-01-10 | 2004-01-02 | Centre Nat Rech Scient | Cellules du tissu adipeux extramedullaire et leurs applications dans la reconstitution des lignees hematopoietiques |
-
2000
- 2000-03-10 KR KR1020097007343A patent/KR100968165B1/ko not_active IP Right Cessation
- 2000-03-10 BR BR0008552-9A patent/BR0008552A/pt not_active Application Discontinuation
- 2000-03-10 KR KR1020087014477A patent/KR100968164B1/ko not_active IP Right Cessation
- 2000-03-10 AU AU35223/00A patent/AU784580B2/en not_active Expired
- 2000-03-10 KR KR1020077009385A patent/KR100979664B1/ko not_active IP Right Cessation
- 2000-03-10 KR KR1020017011443A patent/KR100870508B1/ko not_active IP Right Cessation
- 2000-03-10 WO PCT/US2000/006232 patent/WO2000053795A1/en not_active Application Discontinuation
- 2000-03-10 CN CN00807461A patent/CN1352696A/zh active Pending
- 2000-03-10 IL IL14500200A patent/IL145002A0/xx unknown
- 2000-03-10 CA CA2366078A patent/CA2366078C/en not_active Expired - Lifetime
- 2000-03-10 EP EP00913860.3A patent/EP1165830B1/en not_active Expired - Lifetime
- 2000-03-10 JP JP2000603416A patent/JP2002537849A/ja active Pending
- 2000-03-10 RU RU2001127430/13A patent/RU2306335C2/ru not_active IP Right Cessation
-
2001
- 2001-09-06 US US09/947,985 patent/US20020076400A1/en not_active Abandoned
-
2005
- 2005-08-24 US US11/211,114 patent/US20050282275A1/en not_active Abandoned
-
2007
- 2007-04-19 RU RU2007114846/13A patent/RU2007114846A/ru not_active Application Discontinuation
-
2010
- 2010-10-27 JP JP2010241400A patent/JP2011078416A/ja active Pending
-
2014
- 2014-11-20 JP JP2014235177A patent/JP2015109834A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2015109834A (ja) | 2015-06-18 |
US20020076400A1 (en) | 2002-06-20 |
KR20090043612A (ko) | 2009-05-06 |
AU3522300A (en) | 2000-09-28 |
KR20080063426A (ko) | 2008-07-03 |
WO2000053795A1 (en) | 2000-09-14 |
EP1165830B1 (en) | 2017-07-12 |
IL145002A0 (en) | 2002-06-30 |
KR20020013510A (ko) | 2002-02-20 |
RU2007114846A (ru) | 2008-11-27 |
JP2011078416A (ja) | 2011-04-21 |
KR100979664B1 (ko) | 2010-09-02 |
KR100968165B1 (ko) | 2010-07-06 |
CA2366078A1 (en) | 2000-09-14 |
EP1165830A4 (en) | 2003-10-08 |
JP2002537849A (ja) | 2002-11-12 |
EP1165830A1 (en) | 2002-01-02 |
KR20070053359A (ko) | 2007-05-23 |
CA2366078C (en) | 2015-09-01 |
KR100968164B1 (ko) | 2010-07-06 |
CN1352696A (zh) | 2002-06-05 |
KR100870508B1 (ko) | 2008-11-25 |
RU2306335C2 (ru) | 2007-09-20 |
AU784580B2 (en) | 2006-05-04 |
US20050282275A1 (en) | 2005-12-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR0008552A (pt) | Células tronco e redes derivadas de tecido adiposo | |
WO2003022988A3 (en) | Adipose-derived stem cells and lattices | |
Joo et al. | The effect of collagen hydrogel on 3D culture of ovarian follicles | |
Rodeck et al. | Metastatic but not primary melanoma cell lines grow in vitro independently of exogenous growth factors | |
TW200516149A (en) | Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair | |
BRPI0510829A (pt) | uso de células tronco mesenquimáticas humanas, procedimento de capacitação in vitro de células condro-osteogênicas a partir de células tronco mesenquimáticas humanas, células com capacidade condro-osteogênica, uso de células com capacidade condro-osteogênica e composição capaz de induzir osteogênesis | |
DE3751843D1 (de) | Herstellung von körperorganen durch kontroliertes zellwachstum auf künstlicher matrix | |
GB2393734A (en) | Cells of the cardiomyocyte lineage produced from human pluripotent stem cells | |
Seruya et al. | Clonal population of adult stem cells: life span and differentiation potential | |
MXPA04004534A (es) | Aumento de la funcion de un organo. | |
GB2414990A (en) | Biologically active native biomatrix composition | |
O'connor et al. | Extracellular matrix substrata alter adipocyte yield and lipogenesis in primary cultures of stromal-vascular cells from human adipose | |
Munir et al. | Hypoxia enhances chondrogenic differentiation of human adipose tissue-derived stromal cells in scaffold-free and scaffold systems | |
Korurer et al. | Production of a composite hyaluronic acid/gelatin blood plasma gel for hydrogel‐based adipose tissue engineering applications | |
Yoshizato et al. | Collagen-dependent growth suppression and changes in the shape of human dermal fibroblasts | |
Hartrianti et al. | Modulating mesenchymal stem cell behavior using human hair keratin‐coated surfaces | |
Hsu et al. | Bioeffect of ultrasound on endothelial cells in vitro | |
Colley et al. | Culture on fibrin matrices maintains the colony-forming capacity and osteoblastic differentiation of mesenchymal stem cells | |
Ghanavati et al. | Characterization of a three-dimensional organotypic co-culture skin model for epidermal differentiation of rat adipose-derived stem cells | |
Schlabe et al. | Isolation and culture of different epidermal and dermal cell types from human scalp suitable for the development of a therapeutical cell spray | |
CN108753710A (zh) | 一种无血清完全培养基及其应用 | |
Yao et al. | Bioactive sutures for tendon repair: assessment of a method of delivering pluripotential embryonic cells | |
DE69737455D1 (de) | Definierte systeme zur kultivieurng epithelialer zellen und anwendung derselben | |
Chernoff et al. | Organization of the migrating chick epiblast edge: Attachment sites, cytoskeleton, and early developmental changes | |
Wang et al. | Fluorapatite enhances mineralization of mesenchymal/endothelial cocultures |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O, 11, 13, 24 E 25 DA LPI. |
|
B12B | Appeal against refusal [chapter 12.2 patent gazette] | ||
B15K | Others concerning applications: alteration of classification |
Ipc: C12N 5/077 (2010.01), C12N 5/00 (2006.01), C12N 5/ |