GB201604304D0 - Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease - Google Patents
Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's diseaseInfo
- Publication number
- GB201604304D0 GB201604304D0 GBGB1604304.4A GB201604304A GB201604304D0 GB 201604304 D0 GB201604304 D0 GB 201604304D0 GB 201604304 A GB201604304 A GB 201604304A GB 201604304 D0 GB201604304 D0 GB 201604304D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- crohn
- disease
- stem cells
- adipose tissue
- derived stromal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 208000011231 Crohn disease Diseases 0.000 title 1
- 210000000577 adipose tissue Anatomy 0.000 title 1
- 206010002156 anal fistula Diseases 0.000 title 1
- 210000000130 stem cell Anatomy 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/35—Fat tissue; Adipocytes; Stromal cells; Connective tissues
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0653—Adipocytes; Adipose tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Developmental Biology & Embryology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Rheumatology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (37)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1604304.4A GB201604304D0 (en) | 2016-03-14 | 2016-03-14 | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
| LTEP17160932.4T LT3219321T (lt) | 2016-03-14 | 2017-03-14 | Stromos kamieninės ląstelės, kilusios iš riebalinio audinio, skirtos panaudoti gydant atsparias gydymui kompleksines perianalines fistules krono ligos atveju |
| DE102017002458.8A DE102017002458B4 (de) | 2016-03-14 | 2017-03-14 | Von adipösem gewebe stammende stromale stammzellen zur verwendung bei der behandlung behandlungsresistenter komplexer perianalfisteln bei morbus crohn |
| HUE17160932A HUE058739T2 (hu) | 2016-03-14 | 2017-03-14 | Adipóz szövetbõl származó stromális õssejtek refrakter komplex perianális fisztulák kezelésében történõ alkalmazásra Crohn-betegségben |
| HRP20220539TT HRP20220539T1 (hr) | 2016-03-14 | 2017-03-14 | Stromalne matične stanice iz masnog tkiva za uporabu u liječenju refraktornih kompleksnih perianalnih fistula kod crohnove bolesti |
| SG10202008992YA SG10202008992YA (en) | 2016-03-14 | 2017-03-14 | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
| CA3017694A CA3017694C (en) | 2016-03-14 | 2017-03-14 | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
| US15/458,509 US10357518B2 (en) | 2016-03-14 | 2017-03-14 | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in Crohn's disease |
| NO20170376A NO345415B1 (en) | 2016-03-14 | 2017-03-14 | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in Crohn's disease. |
| NL2018512A NL2018512B1 (en) | 2016-03-14 | 2017-03-14 | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn’s disease |
| SI201731122T SI3219321T1 (sl) | 2016-03-14 | 2017-03-14 | Iz adipoznega tkiva izpeljane stromalne matične celice za uporabo pri zdravljenju refraktarnih kompleksnih perianalnih fistul pri Crohnovi bolezni |
| EP22163484.3A EP4074322A1 (en) | 2016-03-14 | 2017-03-14 | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
| IL298107A IL298107B2 (en) | 2016-03-14 | 2017-03-14 | Compounds containing stem cells derived from adipose tissue for use in the treatment of recurrent symptoms of complex rectal abscesses in Crohn's disease |
| DK17160932.4T DK3219321T3 (da) | 2016-03-14 | 2017-03-14 | Fedtvævsafledte stromale stamceller til anvendelse til behandling af refraktære komplekse perianale fistler ved crohns sygdom |
| ES201700204A ES2681774B1 (es) | 2016-03-14 | 2017-03-14 | Células madre estromales derivadas de tejido adiposo para el uso en el tratamiento de fistulas perianales complejas en la enfermedad de Crohn |
| EP17160932.4A EP3219321B1 (en) | 2016-03-14 | 2017-03-14 | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
| CN201780017154.3A CN108883135B (zh) | 2016-03-14 | 2017-03-14 | 用于治疗克罗恩病的难治性、复杂性肛周瘘的脂肪组织来源的基质干细胞 |
| IL261730A IL261730B2 (en) | 2016-03-14 | 2017-03-14 | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn’s disease |
| BE2017/5156A BE1024781B1 (de) | 2016-03-14 | 2017-03-14 | Von adipösem gewebe stammende stromale stammzellen zur verwendung bei der behandlung behandlungsresistenter komplexer perianalfisteln bei morbus crohn |
| BR112018068493-7A BR112018068493B1 (pt) | 2016-03-14 | 2017-03-14 | Uso de células-tronco estromais |
| PL17160932T PL3219321T3 (pl) | 2016-03-14 | 2017-03-14 | Zrębowe komórki macierzyste pochodzące z tkanki tłuszczowej do zastosowania do leczenia opornych złożonych przetok okołoodbytowych w chorobie leśniowskiego-crohna |
| AU2017232718A AU2017232718B2 (en) | 2016-03-14 | 2017-03-14 | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
| MX2018010699A MX2018010699A (es) | 2016-03-14 | 2017-03-14 | Celulas madre estromales derivadas del tejido adiposo para uso en el tratamiento de fistulas perianales complejas resistentes en enfermedad de crohn. |
| RU2018131519A RU2742308C2 (ru) | 2016-03-14 | 2017-03-14 | Стромальные стволовые клетки жировой ткани для использования в лечении рефракторных сложных перианальных фистул при болезни крона |
| RS20220355A RS63163B1 (sr) | 2016-03-14 | 2017-03-14 | Stromalne matične ćelije dobijene iz masnog tkiva za upotrebu u lečenju upornih kompleksnih perianalnih fistula kod kronove bolesti |
| GB1704065.0A GB2548490B (en) | 2016-03-14 | 2017-03-14 | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in Crohn's disease |
| PCT/IB2017/051468 WO2017158509A1 (en) | 2016-03-14 | 2017-03-14 | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
| ES17160932T ES2911718T3 (es) | 2016-03-14 | 2017-03-14 | Células madre estromales derivadas de tejido adiposo para su uso en el tratamiento de fístulas perianales complejas resistentes en enfermedad de Crohn |
| KR1020187029414A KR102277789B1 (ko) | 2016-03-14 | 2017-03-14 | 크론병의 난치성 복합 항문주위 누공 치료용 지방 조직 유래 기질 줄기 세포 |
| FR1752073A FR3048614B1 (fr) | 2016-03-14 | 2017-03-14 | Cellules souches stromales derivees du tissu adipeux pour une utilisation dans le traitement des fistules peri-anales complexes refractaires dans la maladie de crohn |
| SG11201807404XA SG11201807404XA (en) | 2016-03-14 | 2017-03-14 | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
| CN202211257331.4A CN115569151A (zh) | 2016-03-14 | 2017-03-14 | 用于治疗克罗恩病的难治性、复杂性肛周瘘的脂肪组织来源的基质干细胞 |
| JP2018548356A JP6931656B2 (ja) | 2016-03-14 | 2017-03-14 | クローン病における肛囲複雑瘻孔の治療において使用するための脂肪組織由来間質幹細胞 |
| US16/452,321 US11273182B2 (en) | 2016-03-14 | 2019-06-25 | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in Crohn's disease |
| JP2021083406A JP2021119789A (ja) | 2016-03-14 | 2021-05-17 | クローン病における肛囲複雑瘻孔の治療において使用するための脂肪組織由来間質幹細胞 |
| US17/671,479 US12213998B2 (en) | 2016-03-14 | 2022-02-14 | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in Crohn's disease |
| CY20221100296T CY1125513T1 (el) | 2016-03-14 | 2022-04-20 | Προερχομενα απο λιπωδη ιστο στρωματικα αρχεγονα κυτταρα για χρηση σε αγωγη δυσαγωγων περιπλοκων περιπρωκτικων συριγγιων σε νοσο toy crohn |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1604304.4A GB201604304D0 (en) | 2016-03-14 | 2016-03-14 | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB201604304D0 true GB201604304D0 (en) | 2016-04-27 |
Family
ID=55952284
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB1604304.4A Ceased GB201604304D0 (en) | 2016-03-14 | 2016-03-14 | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
| GB1704065.0A Active GB2548490B (en) | 2016-03-14 | 2017-03-14 | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in Crohn's disease |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1704065.0A Active GB2548490B (en) | 2016-03-14 | 2017-03-14 | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in Crohn's disease |
Country Status (27)
| Country | Link |
|---|---|
| US (3) | US10357518B2 (enExample) |
| EP (2) | EP4074322A1 (enExample) |
| JP (2) | JP6931656B2 (enExample) |
| KR (1) | KR102277789B1 (enExample) |
| CN (2) | CN115569151A (enExample) |
| AU (1) | AU2017232718B2 (enExample) |
| BE (1) | BE1024781B1 (enExample) |
| CA (1) | CA3017694C (enExample) |
| CY (1) | CY1125513T1 (enExample) |
| DE (1) | DE102017002458B4 (enExample) |
| DK (1) | DK3219321T3 (enExample) |
| ES (2) | ES2911718T3 (enExample) |
| FR (1) | FR3048614B1 (enExample) |
| GB (2) | GB201604304D0 (enExample) |
| HR (1) | HRP20220539T1 (enExample) |
| HU (1) | HUE058739T2 (enExample) |
| IL (2) | IL298107B2 (enExample) |
| LT (1) | LT3219321T (enExample) |
| MX (1) | MX2018010699A (enExample) |
| NL (1) | NL2018512B1 (enExample) |
| NO (1) | NO345415B1 (enExample) |
| PL (1) | PL3219321T3 (enExample) |
| RS (1) | RS63163B1 (enExample) |
| RU (1) | RU2742308C2 (enExample) |
| SG (2) | SG10202008992YA (enExample) |
| SI (1) | SI3219321T1 (enExample) |
| WO (1) | WO2017158509A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060045872A1 (en) | 2004-08-25 | 2006-03-02 | Universidad Autonoma De Madrid Ciudad Universitaria de Cantoblanco | Use of adipose tissue-derived stromal stem cells in treating fistula |
| GB201604304D0 (en) * | 2016-03-14 | 2016-04-27 | Tigenix S A U | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
| AU2018244922A1 (en) | 2017-03-30 | 2019-09-12 | Biora Therapeutics, Inc. | Treatment of a disease of the gastrointestinal tract with live biotherapeutics |
| CN113544261B (zh) * | 2019-02-27 | 2024-10-01 | 武田药品工业株式会社 | 用于同种异体疗法的改良的干细胞群 |
| WO2021180850A1 (en) * | 2020-03-11 | 2021-09-16 | Mesoblast International Sàrl | Method for treating inflammatory bowel disease i |
| BR112022018022A2 (pt) * | 2020-03-11 | 2022-10-18 | Mesoblast Int Sarl | Método para tratar doença inflamatória intestinal ii |
| CN111481573A (zh) * | 2020-03-26 | 2020-08-04 | 卡替（上海）生物技术股份有限公司 | 牙髓间充质干细胞在制备克罗恩病治疗药物中的用途 |
| CA3200227A1 (en) * | 2020-11-25 | 2022-06-02 | Alexandra Sophie DE BOER | Adipogenic cell compositions and methods |
| WO2023230524A1 (en) * | 2022-05-25 | 2023-11-30 | Flagship Pioneering Innovations Vi, Llc | Compositions of secretory and/or catalytic cells and methods using the same |
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