LT3142B - New sweetening materials and method for the preparing them - Google Patents

New sweetening materials and method for the preparing them Download PDF

Info

Publication number
LT3142B
LT3142B LTIP1457A LTIP1457A LT3142B LT 3142 B LT3142 B LT 3142B LT IP1457 A LTIP1457 A LT IP1457A LT IP1457 A LTIP1457 A LT IP1457A LT 3142 B LT3142 B LT 3142B
Authority
LT
Lithuania
Prior art keywords
compounds
cooh
aspartame
hydroxy
methoxyphenyl
Prior art date
Application number
LTIP1457A
Other languages
English (en)
Lithuanian (lt)
Inventor
Claude Nofre
Jean-Marie Tinti
Original Assignee
Claude Nofre
Tinti Jean Marie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Claude Nofre, Tinti Jean Marie filed Critical Claude Nofre
Publication of LTIP1457A publication Critical patent/LTIP1457A/xx
Publication of LT3142B publication Critical patent/LT3142B/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/31—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives
    • A23L27/32—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives containing dipeptides or derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Seasonings (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Liquid Crystal Substances (AREA)
  • Fats And Perfumes (AREA)
LTIP1457A 1992-11-12 1993-11-10 New sweetening materials and method for the preparing them LT3142B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9213615A FR2697844B1 (fr) 1992-11-12 1992-11-12 Nouveaux composés dérivés de dipeptides ou d'analogues dipeptidiques utiles comme agents édulcorants, leur procédé de préparation.

Publications (2)

Publication Number Publication Date
LTIP1457A LTIP1457A (en) 1994-06-15
LT3142B true LT3142B (en) 1995-01-31

Family

ID=9435473

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP1457A LT3142B (en) 1992-11-12 1993-11-10 New sweetening materials and method for the preparing them

Country Status (32)

Country Link
US (1) US5480668A (ko)
EP (1) EP0669935B1 (ko)
JP (1) JP2818032B2 (ko)
KR (1) KR100254297B1 (ko)
CN (1) CN1038747C (ko)
AT (1) ATE138935T1 (ko)
AU (1) AU664663B2 (ko)
BG (1) BG61609B1 (ko)
CA (1) CA2139233C (ko)
CZ (1) CZ285018B6 (ko)
DE (1) DE69303032T2 (ko)
DK (1) DK0669935T3 (ko)
EC (1) ECSP930999A (ko)
EE (1) EE03194B1 (ko)
ES (1) ES2091114T3 (ko)
FI (1) FI114314B (ko)
FR (1) FR2697844B1 (ko)
GR (1) GR3020164T3 (ko)
HU (1) HU218158B (ko)
IL (1) IL107551A (ko)
LT (1) LT3142B (ko)
MD (1) MD1450G2 (ko)
NO (1) NO309862B1 (ko)
NZ (1) NZ257870A (ko)
PL (1) PL177090B1 (ko)
RO (1) RO112621B1 (ko)
RU (1) RU2107071C1 (ko)
SK (1) SK280180B6 (ko)
TW (1) TW260673B (ko)
UA (1) UA39869C2 (ko)
WO (1) WO1994011391A1 (ko)
ZA (1) ZA938430B (ko)

Families Citing this family (134)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030036980A1 (en) * 2001-08-14 2003-02-20 Wren Stephen C. System for marketing goods and services utilizing computerized central and remote facilities
FR2719590B1 (fr) * 1994-05-09 1996-07-26 Claude Nofre Procédé perfectionné de préparation d'un composé dérivé de l'aspartame utile comme agent édulcorant.
JPH09323966A (ja) 1996-01-12 1997-12-16 Ajinomoto Co Inc 新規アスパルチルアミド誘導体及び甘味剤
FR2744454B1 (fr) * 1996-02-07 1998-04-24 Nofre Claude Acide n-(3,3-dimethylbutyl)-l-aspartyl-d-alpha- aminoalcanoique n-(s)-1-phenyl-1-alcanamide utile comme agent edulcorant
US5728862A (en) * 1997-01-29 1998-03-17 The Nutrasweet Company Method for preparing and purifying an N-alkylated aspartame derivative
US5770775A (en) * 1997-02-10 1998-06-23 The Nutrasweet Company Method for preparing 3,3-dimethylbutyraldehyde
DE69739895D1 (de) * 1997-03-10 2010-07-08 Ajinomoto Kk Süßstoffzusammensetzung mit verbessertem Geschmack, ihre Verwendung und Herstellungsverfahren
JPH10259194A (ja) * 1997-03-18 1998-09-29 Ajinomoto Co Inc 新規ジペプチド誘導体及び甘味剤
US5973209A (en) * 1997-07-11 1999-10-26 The Nutrasweet Company Method for preparing 3, 3-dimethybutyraldehyde
US6291004B1 (en) 1997-09-11 2001-09-18 The Nutrasweet Company Basic salts of n-[n-(3,3-dimethylbutyl)-l-α-aspartyl]-l-phenylalanine 1-methyl ester
US6146680A (en) * 1997-09-11 2000-11-14 The Nutrasweet Company Metal complexes of N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester
US6129942A (en) * 1997-09-11 2000-10-10 The Nutrasweet Company Sweetener salts of N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester
US6180156B1 (en) * 1997-09-11 2001-01-30 The Nutrasweet Company Acid salts of N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester
JPH1180108A (ja) * 1997-09-12 1999-03-26 Ajinomoto Co Inc 甘味料の精製法
JPH11130794A (ja) * 1997-10-23 1999-05-18 Ajinomoto Co Inc アスパルテーム誘導体の精製方法
JPH11171895A (ja) 1997-12-11 1999-06-29 Ajinomoto Co Inc アスパルテームとアスパルテーム誘導体の分離精製方法
JPH11169132A (ja) * 1997-12-15 1999-06-29 Ajinomoto Co Inc アスパルテームとアスパルテーム誘導体の混晶及びその製造方法
JPH11169133A (ja) * 1997-12-15 1999-06-29 Ajinomoto Co Inc アスパルテーム及びアスパルテーム誘導体を含有する甘味料組成物
AU2006599A (en) * 1997-12-17 1999-07-05 Nutrasweet Company, The Use of n-{n-(3,3-dimethylbutyl)-l-alpha-aspartyl}-l-phenylalanine 1-methyl esterin baked goods, frostings and bakery fillings
AU1936499A (en) * 1997-12-17 1999-07-05 Nutrasweet Company, The Use of n-{n-(3,3-dimethylbutyl)-l-alpha-aspartyl}-l-phenylalanine 1-methyl esterin dairy and dairy analogue products
AR015498A1 (es) * 1997-12-17 2001-05-02 Nutrasweet Co Composiciones de edulcorante de mesa.
AR014129A1 (es) * 1997-12-17 2001-02-07 Nutrasweet Co Bebida que comprende fundamentalmente un ester n-[n-(3,3-dimetilbutil)-l- alfa-aspartil]-l-fenilamina 1 - metilico, bebida sin alcohol carbonatada,bebida de jugo, bebida envasada caliente y bebida deportiva de bajas calorias.
CN1181090C (zh) * 1998-04-09 2004-12-22 味之素株式会社 天冬氨酰基二肽酯衍生物及甜味剂
JP2000026496A (ja) * 1998-05-08 2000-01-25 Ajinomoto Co Inc 新規アスパルテーム誘導体結晶及びその製造法
JP3643921B2 (ja) * 1998-05-08 2005-04-27 味の素株式会社 新規甘味料組成物
JP3643922B2 (ja) * 1998-05-08 2005-04-27 味の素株式会社 甘味料組成物
US5905175A (en) * 1998-05-20 1999-05-18 The Nutrasweet Company Synthesis and purification of 3,3-dimethylbutyraldehyde via oxidation of 1-chloro-3,3-dimethylbutane with dimethyl sulfoxide
AU2003213469B2 (en) * 1998-06-05 2005-12-22 Wm. Wrigley Jr. Company Method of Controlling Release of N-substituted Derivatives of Aspartame in Chewing Gum and Gum Produced Thereby
AU2006203624B2 (en) * 1998-06-05 2008-07-10 Wm. Wrigley Jr. Company Method of controlling release of N-substituted derivatives of aspartame in chewing gum and gum produced thereby
DK1083799T3 (da) * 1998-06-05 2011-01-10 Wrigley W M Jun Co Fremgangsmåde til kontrol af frigørelse af N-substituerede derivater af aspartam i tyggegummi og tyggegummi produceret dermed
US6692778B2 (en) 1998-06-05 2004-02-17 Wm. Wrigley Jr. Company Method of controlling release of N-substituted derivatives of aspartame in chewing gum
HUP0103426A3 (en) * 1998-06-26 2004-09-28 Ajinomoto Kk Novel aspartyl dipeptide ester derivatives and sweeteners
US5977415A (en) * 1998-08-20 1999-11-02 The Nutrasweet Company Preparation of 3, 3-dimethylbutyraldehyde from a tert-butyl cation precursor, vinyl chloride and an acidic catalyst
US6214402B1 (en) * 1998-09-17 2001-04-10 The Nutrasweet Company Co-crystallization of sugar and n-[n-(3,3-dimethylbutyl)-l αaspartyl]-l-phenylalanine 1-methyl ester
WO2000015049A1 (en) * 1998-09-17 2000-03-23 The Nutrasweet Company THE USE OF CYCLODEXTRIN TO STABILIZE N-[N- (3,3-DIMETHYLBUTYL) -1-α- ASPARTYL] -L-PHENYLALANINE 1-METHYL ESTER
US5994593A (en) * 1998-09-17 1999-11-30 The Nutrasweet Company Synthesis and purification of 3,3-dimethylbutyraldehyde via hydrolysis of 1,1-dichloro-3,3-dimethylbutane or 1-bromo-1-chloro-3,3-dimethylbutane
HUP0103979A3 (en) * 1998-09-18 2003-05-28 Ajinomoto Kk N-alkylaspartyldipeptide ester derivatives and sweeteners
US6844465B2 (en) * 1998-10-30 2005-01-18 Ajinomoto Co., Inc. Method for preparing highly stable crystals of aspartame derivative
US6465677B1 (en) 1998-11-19 2002-10-15 The Nutrasweet Company Method for the preparation of N-neohexyl-α-aspartyl-L-phenylalanine methyl ester from imidazolidin-4-one intermediates
AU1628700A (en) 1998-11-20 2000-06-13 Nutrasweet Company, The Amorphous N-(N-(3,3-dimethylbutyl)-l-alpha-aspartyl)-l-phenylalanine 1-methyl ester
US6423864B1 (en) 1998-11-25 2002-07-23 The Nutrasweet Company Purification of N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester via crystallization
US20020164397A1 (en) * 1998-12-18 2002-11-07 Subbarao V. Ponakala N-[n-(3, 3-dimethylbutyl)-l-alpha-aspartyl]-l-phenylalanine 1-methyl ester as a sweetener in chewing gum
US20030008046A1 (en) * 1998-12-18 2003-01-09 Paula A. Gerlat Use of n-neohexyl-a-aspartyl-l-phenylalanine methyl ester as a flavor modifier
US6077962A (en) * 1998-12-24 2000-06-20 The Nutrasweet Company N-3, 3-dimethylbutyl-L-aspartic acid and esters thereof, the process of preparing the same, and the process for preparing N-(N-(3,3-dimethylbutyl) -α L-aspartyl)-L- phenylalanine 1-methyl ester therefrom
US6048999A (en) * 1999-01-25 2000-04-11 The Nutrasweet Company N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester synergistic sweetener blends
US6180157B1 (en) * 1999-02-18 2001-01-30 The Nutrasweet Company Process for preparing an N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester agglomerate
WO2000052019A2 (en) * 1999-03-03 2000-09-08 The Nutrasweet Company Crystallization products of neotame and methods for producing same
AU3914200A (en) * 1999-03-25 2000-10-09 Nutrasweet Company, The Edible gels sweetened with n-(n-(3,3-dimethylbutyl)-l-alpha-aspartyl)-l-phenylalanine 1-methyl ester
EP1164872A1 (en) 1999-03-26 2002-01-02 The NutraSweet Company PARTICLES OF N- N-(3,3-DIMETHYLBUTYL)-L-$g(a)-ASPARTYL]-L-PHENYLALANINE 1-METHYL ESTER
WO2000069283A1 (en) * 1999-05-13 2000-11-23 The Nutrasweet Company USE OF ADDITIVES TO MODIFY THE TASTE CHARACTERISTICS OF N-NEOHEXYL-α-ASPARTYL-L-PHENYLALANINE METHYL ESTER
US6573409B1 (en) * 1999-07-02 2003-06-03 The Nutrasweet Company Process for the preparation of 3,3-dimethylbutanal
WO2001009168A1 (en) 1999-07-28 2001-02-08 The Nutrasweet Company A METHOD FOR THE PURIFICATION OF N-[N-(3,3-DIMETHYLBUTYL)-L-α-ASPARTYL]-L-PHENYLALANINE 1-METHYL ESTER
WO2001010241A2 (en) * 1999-08-06 2001-02-15 The Nutrasweet Company PROCESS FOR COATING N-[N-(3,3-DIMETHYLBUTYL)-L-α-ASPARTYL]-L-PHENYLALANINE 1-METHYL ESTER ONTO A CARRIER
AU6238800A (en) * 1999-08-11 2001-03-05 Nutrasweet Company, The Confectionery food products sweetened with n-[n-(3,3-dimethylbutyl)-1-alpha-aspartyl]-l-phenylalanine methyl ester
CA2383137A1 (en) * 1999-09-07 2001-03-15 Ajinomoto Co., Inc. Method for producing aspartame derivative, method for purifying the same, crystals thereof and uses of the same
JP2001097998A (ja) * 1999-10-01 2001-04-10 Ajinomoto Co Inc アスパルチルジペプチドエステル誘導体及び甘味剤
KR20020037065A (ko) * 1999-10-04 2002-05-17 에가시라 구니오 감미질이 개선된 고감미도 감미료 조성물, 미각 교정제 및이들의 용도
RU2002111688A (ru) 1999-10-05 2003-12-10 Адзиномото Ко., Инк. (Jp) Твердые подслащивающие композиции, жидкие подслащивающие композиции и их применение
AU7321800A (en) 1999-10-07 2001-05-10 Ajinomoto Co., Inc. Processes for producing and purifying aspartame derivatives and process for producing production intermediates
US20040176472A1 (en) * 1999-10-07 2004-09-09 Ajinomoto Co., Inc. Process for production of aspartyl dipeptide ester derivative, novel production intermediate therefor, and process for production thereof
EP1231215A4 (en) * 1999-10-07 2004-07-14 Ajinomoto Kk PROCESS FOR PRODUCING ASPARTYLDIPEPTIDE ESTER DERIVATIVES, NOVEL MATCHING INTERMEDIATES AND PROCESS FOR PRODUCING SUCH INTERMEDIATES
AU7556700A (en) * 1999-10-08 2001-04-23 Ajinomoto Co., Inc. Process for producing aspartame derivative, crystals thereof, novel production intermediates therefor and process for producing the intermediate
AU8027700A (en) * 1999-10-19 2001-04-30 Nutrasweet Company, The Use of n-'n-(3,3 dimethylbutyl)-l-alpha-aspartyl-l-phenylalanine 1-methyl ester (neotame) to modify mouthfeel perception
CN1391553A (zh) * 1999-11-18 2003-01-15 味之素株式会社 高甜度甜味剂用的新型中间体以及它的制造方法
WO2001047949A1 (fr) * 1999-12-28 2001-07-05 Ajinomoto Co., Inc. Cristaux de derives d'aspartame
JP2001199930A (ja) * 2000-01-20 2001-07-24 Ajinomoto Co Inc 新規アリ−ルプロピルアルデヒド誘導体、その製造法及びその使用等
US7041277B2 (en) * 2000-03-10 2006-05-09 Cadbury Adams Usa Llc Chewing gum and confectionery compositions with encapsulated stain removing agent compositions, and methods of making and using the same
EP1283213A1 (en) * 2000-05-10 2003-02-12 Ajinomoto Co., Inc. Process for producing aspartyl dipeptide ester derivatives
US6627431B1 (en) 2000-05-12 2003-09-30 The Nutrasweet Company Chemoenzymatic synthesis of neotame
DE60140250D1 (de) * 2000-05-16 2009-12-03 Ajinomoto Kk Verfahren zur herstellung von cinnamylaldehyd-derivaten und ihre verwendung
WO2001087927A2 (en) 2000-05-18 2001-11-22 The Nutrasweet Company gYNTHESIS OF N-[N-(3,3-DIMETHYLBUTYL)-L-α-ASPARTYL]-L-PHENYLALANINE 1-METHYL ESTER USING L-α-ASPARTYL-L-PHENYLALANINE 1-METHYL ESTER PRECURSORS
US6281380B1 (en) * 2000-05-18 2001-08-28 The Nutra Sweet Company Synthesis of N-(N-(3,3-dimethylbutyl)-L-α-aspartyl)L-phenylalanine1-methyl ester by reductive alkylation and crystallization/ isolation in aqueous methanol
DE60108745T2 (de) * 2000-05-19 2005-07-07 The Nutrasweet Co., Chicago Herstellung von N-[N-(3,3-Dimethylbutyl)-L-α-aspartyl]-L-phenylalanin-1-methylester mittels Oxazolidinonderivate
US7326430B2 (en) * 2000-07-18 2008-02-05 The Nutrasweet Company Method of preparing liquid compositions for delivery of N-[N- (3,3-dimethylbutyl-L-α-aspartyl]-L-phenylalanine 1-methyl ester in food and beverage systems
JPWO2002062746A1 (ja) * 2001-02-08 2004-06-03 味の素株式会社 新規ｎ−アルキルアスパルチルアミド誘導体及び甘味剤
US6992069B2 (en) * 2002-04-30 2006-01-31 Yu-Gui Gu Tricyclic macrolide antibacterial compounds
CN101565451B (zh) * 2003-05-06 2013-03-27 纽特拉斯威特公司 N-[N-(3,3-二甲基丁基)-L-α-天冬氨酰基]-L-苯基丙氨酸1-甲酯
JP2004121222A (ja) * 2003-05-29 2004-04-22 Ajinomoto Co Inc 甘味料組成物
US20050112236A1 (en) * 2003-11-21 2005-05-26 Navroz Boghani Delivery system for active components as part of an edible composition having preselected tensile strength
US20060263474A1 (en) * 2005-05-23 2006-11-23 Cadbury Adams Usa Llc. Enhanced flavor-release comestible compositions and methods for same
US8591968B2 (en) * 2005-05-23 2013-11-26 Kraft Foods Global Brands Llc Edible composition including a delivery system for active components
US8591973B2 (en) * 2005-05-23 2013-11-26 Kraft Foods Global Brands Llc Delivery system for active components and a material having preselected hydrophobicity as part of an edible composition
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US8389031B2 (en) * 2005-05-23 2013-03-05 Kraft Foods Global Brands Llc Coated delivery system for active components as part of an edible composition
US20060263473A1 (en) * 2005-05-23 2006-11-23 Cadbury Adams Usa Llc Compressed delivery system for active components as part of an edible composition
US8591972B2 (en) * 2005-05-23 2013-11-26 Kraft Foods Global Brands Llc Delivery system for coated active components as part of an edible composition
US9271904B2 (en) * 2003-11-21 2016-03-01 Intercontinental Great Brands Llc Controlled release oral delivery systems
US8597703B2 (en) * 2005-05-23 2013-12-03 Kraft Foods Global Brands Llc Delivery system for active components as part of an edible composition including a ratio of encapsulating material and active component
US8591974B2 (en) 2003-11-21 2013-11-26 Kraft Foods Global Brands Llc Delivery system for two or more active components as part of an edible composition
CA2558683A1 (en) * 2004-03-05 2005-09-22 Sunil Srivastava High-intensity sweetener-polyol compositions
US20050208190A1 (en) * 2004-03-16 2005-09-22 Kraft Foods Holdings, Inc. Method for drying neotame with co-agents
US20060068058A1 (en) * 2004-09-30 2006-03-30 Cadbury Adams Usa Llc Thermally stable, high tensile strength encapsulation compositions for actives
US7727565B2 (en) 2004-08-25 2010-06-01 Cadbury Adams Usa Llc Liquid-filled chewing gum composition
US7955630B2 (en) * 2004-09-30 2011-06-07 Kraft Foods Global Brands Llc Thermally stable, high tensile strength encapsulated actives
US20060263476A1 (en) * 2004-08-25 2006-11-23 Cadbury Adams Usa, Llc. Center-filled chewing gum with barrier layer
US20060068059A1 (en) * 2004-09-30 2006-03-30 Cadbury Adams Usa Llc Encapsulated compositions and methods of preparation
US9198448B2 (en) * 2005-02-07 2015-12-01 Intercontinental Great Brands Llc Stable tooth whitening gum with reactive ingredients
AR053295A1 (es) * 2005-05-23 2007-04-25 Cadbury Adams Usa Llc Composiciones que potencian el sabor y golosinas comestibles y productos de goma de mascar que los contienen
US7851006B2 (en) * 2005-05-23 2010-12-14 Cadbury Adams Usa Llc Taste potentiator compositions and beverages containing same
US7851005B2 (en) * 2005-05-23 2010-12-14 Cadbury Adams Usa Llc Taste potentiator compositions and beverages containing same
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US9011946B2 (en) 2011-04-29 2015-04-21 Intercontinental Great Brands Llc Encapsulated acid, method for the preparation thereof, and chewing gum comprising same
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US20180116265A1 (en) * 2016-10-31 2018-05-03 Morris IP Holdings LLC Blended high-intensity sweetener composition

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3492131A (en) 1966-04-18 1970-01-27 Searle & Co Peptide sweetening agents
EP0107597B1 (fr) 1982-09-17 1986-02-26 Universite Claude Bernard - Lyon 1 Composés chimiques et utilisation comme édulcorants
EP0338946B1 (fr) 1988-04-22 1992-07-01 NOFRE, Claude Agents édulcorants dérivant des acides L-aspartique et L-glutamique N-hydrocarbonés

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3475403A (en) * 1967-01-20 1969-10-28 Searle & Co Aspartic acid containing dipeptide lower alkyl esters
FR2579202B1 (fr) * 1985-03-19 1988-04-29 Univ Claude Bernard Lyon Nouveaux composes chimiques, utilisation comme agents edulcorants et compositions contenant de tels agents
US4921939A (en) * 1985-03-19 1990-05-01 Universite Claude Bernard -Lyon 1 Sweetening agents
FR2579201B1 (fr) * 1985-03-19 1987-05-07 Bernard Lyon I Universite Clau Composes chimiques perfectionnes, utilisation comme agents edulcorants et compositions contenant de tels agents
FR2624699B1 (fr) * 1987-12-18 1990-04-13 Bernard Lyon I Universite Clau Derives heterocycliques de n-carbamoyl-, n-thiocarbamoyl- ou n-amidino-glycine ou beta-alanine utiles comme agents edulcorants
EP0334236B1 (en) * 1988-03-22 1994-08-31 MITSUI TOATSU CHEMICALS, Inc. Preparation of n-protected alpha-l-aspartyl-l-phenylalanine methyl ester
FR2653303B1 (fr) * 1989-10-24 1992-09-18 Noffre Claude Agents edulcorants de grande stabilite derivant des acides l-aspartique et l-glutamique n-hydrocarbones 1-oxo-2-ramifies.
FR2675667B1 (fr) * 1991-04-23 1993-08-20 Claude Nofre Agent edulcorant derivant a l'acide l-aspartique ou l-glutamique; son procede de preparation.

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3492131A (en) 1966-04-18 1970-01-27 Searle & Co Peptide sweetening agents
EP0107597B1 (fr) 1982-09-17 1986-02-26 Universite Claude Bernard - Lyon 1 Composés chimiques et utilisation comme édulcorants
EP0338946B1 (fr) 1988-04-22 1992-07-01 NOFRE, Claude Agents édulcorants dérivant des acides L-aspartique et L-glutamique N-hydrocarbonés

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
J. M. JANUSZ: "Progress in sweeteners", pages: 46

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