LT2420498T - 5-pakeistieji chinazolinono dariniai, kaip priešvėžiniai agentai - Google Patents

5-pakeistieji chinazolinono dariniai, kaip priešvėžiniai agentai

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Publication number
LT2420498T
LT2420498T LTEP11174056.9T LT11174056T LT2420498T LT 2420498 T LT2420498 T LT 2420498T LT 11174056 T LT11174056 T LT 11174056T LT 2420498 T LT2420498 T LT 2420498T
Authority
LT
Lithuania
Prior art keywords
cancer agents
quinazolinone derivatives
substituted quinazolinone
substituted
derivatives
Prior art date
Application number
LTEP11174056.9T
Other languages
English (en)
Lithuanian (lt)
Inventor
George W. Muller
Hon-Wah Man
Original Assignee
Celgene Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Corporation filed Critical Celgene Corporation
Publication of LT2420498T publication Critical patent/LT2420498T/lt

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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
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    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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