CO6160323A2 - Derivados de quinazolinona 5-sustituidos como agentes antitumorales - Google Patents

Derivados de quinazolinona 5-sustituidos como agentes antitumorales

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Publication number
CO6160323A2
CO6160323A2 CO09041135A CO09041135A CO6160323A2 CO 6160323 A2 CO6160323 A2 CO 6160323A2 CO 09041135 A CO09041135 A CO 09041135A CO 09041135 A CO09041135 A CO 09041135A CO 6160323 A2 CO6160323 A2 CO 6160323A2
Authority
CO
Colombia
Prior art keywords
halo
optionally substituted
alkyl
hydrogen
aryl
Prior art date
Application number
CO09041135A
Other languages
English (en)
Spanish (es)
Inventor
George W Muller
Hon-Wah Man
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Corp filed Critical Celgene Corp
Publication of CO6160323A2 publication Critical patent/CO6160323A2/es

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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
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